Peptidomics analysis reveals changes in small urinary peptides in patients with interstitial cystitis/bladder pain syndrome

Author

Md Shadman Ridwan Abid, Haowen Qiu3, Bridget A. Tripp, Aline de Lima Leite, Heidi E. Roth, Jiri Adamec, Robert Powers & James W. Checco

Published

May 18, 2022

Doi
Abstract
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic and debilitating pain disorder of the bladder and urinary tract with poorly understood etiology. A definitive diagnosis of IC/BPS can be challenging because many symptoms are shared with other urological disorders. An analysis of urine presents an attractive and non-invasive resource for monitoring and diagnosing IC/BPS. The antiproliferative factor (APF) peptide has been previously identified in the urine of IC/BPS patients and is a proposed biomarker for the disorder. Nevertheless, other small urinary peptides have remained uninvestigated in IC/BPS primarily because protein biomarker discovery efforts employ protocols that remove small endogenous peptides. The purpose of this study is to investigate the profile of endogenous peptides in IC/BPS patient urine, with the goal of identifying putative peptide biomarkers. Here, a non-targeted peptidomics analysis of urine samples collected from IC/BPS patients were compared to urine samples from asymptomatic controls. Our results show a general increase in the abundance of urinary peptides in IC/BPS patients, which is consistent with an increase in inflammation and protease activity characteristic of this disorder. In total, 71 peptides generated from 39 different proteins were found to be significantly altered in IC/BPS. Five urinary peptides with high variable importance in projection (VIP) coefficients were found to reliably differentiate IC/BPS from healthy controls by receiver operating characteristic (ROC) analysis. In parallel, we also developed a targeted multiple reaction monitoring method to quantify the relative abundance of the APF peptide from patient urine samples. Although the APF peptide was found in moderately higher abundance in IC/BPS relative to control urine, our results show that the APF peptide was inconsistently present in urine, suggesting that its utility as a sole biomarker of IC/BPS may be limited. Overall, our results revealed new insights into the profile of urinary peptides in IC/BPS that will aid in future biomarker discovery and validation efforts.
Code
suppressPackageStartupMessages(c(
  library(tidyverse),
  library(openxlsx),
  library(janitor),
  library(knitr),
  library(impute),
  library(cowplot),
  library(proBatch),
  library(pcaMethods),
  library(pROC)
  ))
# get start time
start_time <- Sys.time()

Project and data background

In this study, we applied a non-targeted LC–MS and LC–MS/MS-based peptidomics approach to urine collected from IC/BPS patients and asymptomatic controls to explore differences in the profile of small urinary peptides in this disorder (a). These experiments identified several peptides that can be used to differentiate IC/BPS urine from controls. In parallel, we also developed and applied a targeted LC-multiple reaction monitoring (MRM) method to compare the relative quantities of the APF peptide present in urine from both IC/BPS patients and asymptomatic controls (b).

(a) Non-targeted LC–MS and LC–MS/MS peptidomics analysis used to identify urinary peptides that differ between IC/BPS patients and healthy controls. (b) Targeted LC-MRM analysis used to determine the relative quantities of the APF peptide in urine from both IC/BPS patients and healthy controls.

Label-free peptidomics

A total of 995 individual peptides were identified (fragments from 149 different proteins) from the LC–MS and LC–MS/MS datasets using PEAKS Studio proteomics software with a 1% false discovery rate (FDR) threshold. Only 212 peptides with unambiguous sequence assignments were detected in at least 50% of the samples.

Code
FDR <- 0.05
LOG2FC <- 0.6

fh <- openxlsx::read.xlsx("https://static-content.springer.com/esm/art%3A10.1038%2Fs41598-022-12197-2/MediaObjects/41598_2022_12197_MOESM1_ESM.xlsx", sheet = 2, colNames = FALSE) %>%
        as_tibble() %>%
        select(-c(2:8))

df = fh %>%
        janitor::row_to_names(row_number = 2, remove_rows_above = FALSE) %>%
        janitor::clean_names() %>%
        as.data.frame() 

labels_d1 <- as.matrix(df[1,-1]) %>%
        `rownames<-`("Label")

d1 = df[-1,] %>%
        as_tibble() %>%
        column_to_rownames(., var = "peptide_sequence") %>%
        mutate(across(everything(), as.numeric))
anno = data.frame(Label = as.factor(t(df)[-1, 1]))
#sum(d1==0) ## Total missing values
d1[d1 == 0] <- NA ## Change zeros to NA
#sum(is.na(d1))

Data preview

Code
# display table
d1 %>% 
        knitr::kable(., digits = 3, "html") %>%
        kableExtra::kable_styling(bootstrap_options = c("striped", "hover", "condensed", "responsive")) %>%
        kableExtra::scroll_box(width = "100%", height = "500px")
sample_1 sample_2 sample_3 sample_4 sample_5 sample_6 sample_7 sample_8 sample_17 sample_18 sample_19 sample_20 sample_21 sample_22 sample_23 sample_24 sample_33 sample_34 sample_35 sample_36 sample_37 sample_38 sample_39 sample_40 sample_49 sample_50 sample_51 sample_52 sample_56 sample_57 sample_58 sample_59 sample_60 sample_61 sample_62 sample_63 sample_72 sample_73 sample_74 sample_75 sample_76 sample_77 sample_78 sample_79 sample_9 sample_10 sample_11 sample_12 sample_13 sample_14 sample_15 sample_16 sample_25 sample_26 sample_27 sample_28 sample_29 sample_30 sample_31 sample_32 sample_41 sample_42 sample_43 sample_44 sample_45 sample_46 sample_47 sample_48 sample_53 sample_54 sample_55 sample_64 sample_65 sample_66 sample_67 sample_68 sample_69 sample_70 sample_71 sample_80 sample_81 sample_82 sample_83 sample_84 sample_85 sample_86 sample_87
FAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 483240.0 14458.00 46750.00 3488.60 NA 6250.80 74812.00 6132.80 NA 29991.00 3.4595e+05 37796.00 NA NA 201720.0 3.1276e+05 NA NA 25432.00 46964.00 76000.00 107360.00 115930.00 34030.000 20274.000 21931.000 NA NA 169930.00 137850.0 224500.00 533940.00 437090.00 153480.00 2492.600 NA NA 122430.00 172800.00 745840.00 214210.00 85190.00 43582.0 1447.800 8141.60 1305900.0 4392.40 13656.00 67628.0 8.9270e+05 1.2815e+05 382360.00 1.2577e+05 137080.00 3.5806e+05 8615.70 NA 54956.0 23324.00 216380.0 26390.00 NA NA 3.8299e+04 232130.00 53144.00 NA 18799.000 206990.00 82943.00 25704.00 1447600.0 6.1788e+05 614880.00 223370.00 214660.00 551090.00 69041.00 74080.000 13228.000 27664.00 331980.00 1.6386e+05 50360.00 135290.00 74274.00 277090.00
EEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 1255400.0 145990.00 90310.00 37466.00 2.6938e+04 60068.00 149180.00 24655.00 49614.00 76387.00 6.7041e+05 110000.00 48824.00 55031.00 744170.0 7.3271e+05 380.07 13421.000 464110.00 241140.00 334850.00 381640.00 365090.00 120720.000 53057.000 112520.000 70435.00 22982.000 871540.00 559960.0 685890.00 990340.00 990250.00 468510.00 63299.000 46406.00 85306.000 486830.00 926780.00 3474100.00 943040.00 365080.00 905110.0 106810.000 85074.00 2463400.0 26885.00 140620.00 455020.0 1.3549e+06 4.5913e+05 677250.00 8.1170e+05 362390.00 6.6260e+05 75015.00 98377.00 328500.0 144150.00 615380.0 188980.00 48212.000 26970.00 3.1313e+05 331160.00 69911.00 3.2006e+04 112270.000 879620.00 192100.00 17151.00 2318400.0 1.7746e+06 1746900.00 897280.00 883530.00 2470600.00 259760.00 514100.000 104960.000 265070.00 1755500.00 7.5738e+05 200010.00 846780.00 1000900.00 1072400.00
DADLADGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 475550.0 39349.00 154050.00 32269.00 NA 18440.00 87989.00 4186.50 72688.00 47825.00 7.6113e+05 67119.00 34071.00 63557.00 2863.1 2.4407e+05 2391.10 1968.000 122350.00 120780.00 84461.00 168570.00 169100.00 23135.000 17783.000 41359.000 54557.00 12171.000 217650.00 152380.0 285950.00 238130.00 183380.00 113680.00 4568.600 711.97 2891.900 250010.00 418490.00 471470.00 247220.00 39796.00 278730.0 NA 13893.00 821460.0 17866.00 26987.00 416790.0 4.6808e+05 2.8858e+05 509650.00 6.9628e+05 457580.00 5.2203e+05 48496.00 87373.00 144560.0 70492.00 290520.0 92256.00 14349.000 60574.00 8.3094e+04 476450.00 51337.00 8.5890e+04 21829.000 154700.00 131800.00 35931.00 773120.0 5.0577e+05 729260.00 129400.00 360700.00 321570.00 72187.00 67172.000 37038.000 64878.00 382250.00 1.9950e+05 50882.00 214700.00 233300.00 329830.00
GRPEAQPPPLSSEHKEPVAGDAVPGPKDGSAPEVRGA 96938.0 27788.00 60790.00 NA NA NA 14040.00 NA NA NA 2.0918e+05 NA NA NA NA NA NA NA NA 18301.00 63114.00 118490.00 131350.00 4512.800 5004.800 NA 39029.00 7674.300 NA 42664.0 111580.00 93482.00 89619.00 12231.00 NA NA NA 30418.00 NA 84759.00 NA NA NA NA NA 435320.0 5085.50 NA NA 2.2448e+05 3.7438e+04 60763.00 NA 64480.00 1.3280e+05 NA 49289.00 20263.0 NA NA 21503.00 NA 26819.00 1.5285e+04 525040.00 NA 3.1445e+04 NA 118330.00 427560.00 94752.00 326630.0 3.3148e+05 214250.00 27255.00 51064.00 33444.00 NA NA NA NA 157090.00 1.6969e+05 NA 33959.00 7688.40 172900.00
DLADGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 112590.0 NA NA NA NA NA 17513.00 NA NA NA 1.3451e+05 15472.00 NA NA 76195.0 8.7795e+04 NA NA 33852.00 30866.00 42195.00 74231.00 66745.00 8067.400 NA 24882.000 20762.00 NA 89401.00 63264.0 101560.00 76107.00 57732.00 53199.00 NA NA NA 64715.00 175430.00 238020.00 91637.00 17691.00 167890.0 NA NA 191460.0 NA NA 97988.0 9.2197e+04 5.7254e+04 96635.00 NA 77389.00 8.3941e+04 NA 20618.00 41671.0 NA 84361.0 38583.00 NA 34207.00 3.1003e+04 224720.00 19864.00 2.9547e+04 9823.000 83684.00 73138.00 8164.60 393550.0 2.5551e+05 321070.00 67772.00 NA 138480.00 22596.00 17841.000 NA 23039.00 207250.00 6.0810e+04 22577.00 95629.00 98758.00 159400.00
FAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRA 479520.0 148240.00 166170.00 195500.00 4.4661e+04 78972.00 232960.00 43156.00 NA NA 1.0879e+06 28640.00 NA 58462.00 690780.0 1.8480e+05 NA 7450.100 258950.00 78386.00 277830.00 595790.00 387760.00 208660.000 175800.000 64810.000 197410.00 96851.000 366540.00 458840.0 903150.00 1342700.00 1269300.00 813740.00 68584.000 30911.00 56711.000 700830.00 628250.00 1091800.00 526120.00 214840.00 335530.0 67119.000 81558.00 1512700.0 77323.00 150450.00 414010.0 8.8899e+05 4.1616e+05 439640.00 2.1031e+05 236140.00 5.7426e+05 NA 37666.00 118070.0 NA 596030.0 165850.00 42145.000 151730.00 1.3814e+05 468700.00 160620.00 1.0173e+05 104290.000 561420.00 530940.00 99848.00 2104700.0 1.1274e+06 648420.00 342220.00 178310.00 447640.00 270830.00 293310.000 150570.000 331210.00 239920.00 2.5045e+05 101370.00 197580.00 138040.00 870120.00
AVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 52685.0 NA NA NA NA NA NA NA NA NA 1.7235e+05 NA NA NA NA 1.0165e+04 NA NA 34147.00 26156.00 18034.00 20309.00 65791.00 NA NA 14050.000 NA NA 89616.00 29445.0 167620.00 28557.00 79555.00 5675.90 NA 3425.50 NA 36918.00 157230.00 107850.00 25613.00 7744.20 34675.0 NA NA 140740.0 NA 12398.00 NA 1.0664e+05 NA 33690.00 3.6008e+04 NA 1.1598e+05 NA NA NA NA 34856.0 4612.90 NA NA 3.4403e+04 31990.00 NA NA NA NA 22340.00 4892.60 572550.0 8.5131e+04 62183.00 24517.00 15536.00 58951.00 14681.00 NA 6286.400 3957.40 47279.00 3.3055e+04 8513.80 92048.00 39240.00 43756.00
VADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 58668.0 15961.00 NA NA NA 5408.20 NA NA NA NA NA NA 3263.20 NA NA NA NA 2713.000 10185.00 NA 5078.50 5444.10 10872.00 3166.800 15835.000 4318.600 NA NA 29462.00 22713.0 39179.00 79083.00 54462.00 24652.00 5314.700 NA NA 8292.40 33767.00 52515.00 8937.30 21283.00 NA 5982.500 7567.40 150880.0 NA 23230.00 26074.0 1.3530e+05 NA 30378.00 NA NA NA NA NA 5917.2 NA NA 4310.10 6502.300 1925.90 2.1532e+03 2014.30 1377.20 NA 3611.500 49482.00 3620.70 2474.00 213590.0 3.1288e+04 38323.00 28180.00 NA 113640.00 2468.90 32687.000 NA 9720.40 32067.00 3.7849e+04 2168.80 NA 33679.00 36233.00
EEKAVADTRDQADGSRASVDSGSSEEQGGSSRA 639940.0 246620.00 117160.00 152360.00 NA 123140.00 384790.00 78864.00 NA 84357.00 1.2707e+06 NA 111430.00 49529.00 481760.0 NA 27170.00 40668.000 589920.00 391400.00 824830.00 758880.00 207650.00 145980.000 71754.000 144870.000 503590.00 80706.000 289870.00 322800.0 555360.00 736220.00 603610.00 596930.00 40460.000 157780.00 NA 337600.00 432510.00 1733700.00 903250.00 104460.00 982030.0 131570.000 89422.00 1406300.0 78202.00 198070.00 747840.0 4.7782e+05 4.0592e+05 251780.00 NA 216590.00 NA NA NA 261840.0 NA NA 272640.00 56254.000 222270.00 3.3441e+05 175760.00 334730.00 3.7756e+05 248440.000 241220.00 256020.00 68482.00 1204400.0 1.1143e+06 779040.00 242100.00 715000.00 1027400.00 165040.00 153320.000 335010.000 439310.00 392870.00 4.2183e+05 244440.00 252800.00 316730.00 442890.00
DGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG NA NA NA 60236.00 1.0177e+04 20193.00 103680.00 3439.20 74165.00 47811.00 5.6014e+05 61946.00 43165.00 108230.00 325320.0 2.7237e+05 3737.30 NA 90300.00 151630.00 148350.00 319690.00 301630.00 27446.000 26996.000 60467.000 86409.00 14268.000 421390.00 315160.0 510580.00 403860.00 345740.00 204600.00 NA NA 7294.000 378350.00 772830.00 1009700.00 354830.00 95038.00 699070.0 16606.000 23002.00 NA 38437.00 61491.00 331100.0 NA 3.1253e+05 442610.00 3.0857e+05 316680.00 5.3518e+05 53627.00 123090.00 176920.0 69436.00 260570.0 147570.00 NA 67093.00 6.1363e+04 806010.00 46250.00 8.4007e+04 22956.000 343900.00 249400.00 34181.00 1318500.0 8.9169e+05 766890.00 254030.00 884670.00 690090.00 109210.00 117320.000 69395.000 131130.00 553310.00 3.2032e+05 116840.00 452910.00 404930.00 690390.00
IAVEWESNGQPENNYKTTPPVLDSDGSF NA 1612.90 706330.00 5460.30 NA 1738.80 25158.00 NA 36994.00 NA 1.9649e+05 22533.00 NA 26121.00 65156.0 6.4973e+04 NA NA 31702.00 38025.00 131520.00 169820.00 45198.00 4904.600 537.620 57.819 34451.00 NA NA NA 22456.00 19487.00 13721.00 4174.30 NA NA NA 26824.00 NA 14822.00 52387.00 NA NA NA NA NA NA NA 218230.0 1.3368e+03 8.0936e+04 43985.00 NA 25258.00 4.8256e+04 NA 25290.00 46491.0 64744.00 NA 22841.00 1609.600 NA 1.1080e+05 6099.30 NA 4.2471e+04 1636.700 11648.00 64834.00 15246.00 11951.0 1.0351e+04 7778.30 247.77 17349.00 NA 3731.90 NA 6216.600 117.91 13856.00 1.7343e+04 1445.90 NA NA 21458.00
EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ 49479.0 9550.60 19817.00 3132.00 6.8650e+02 6064.20 36140.00 NA 2076.90 132060.00 1.8128e+05 67387.00 31808.00 55704.00 494800.0 1.0423e+06 4491.00 1933.300 111210.00 54551.00 270840.00 1007000.00 401250.00 87408.000 26245.000 188040.000 390170.00 114660.000 26776.00 89434.0 19467.00 157190.00 58027.00 33439.00 433.920 2769.50 NA 21119.00 33443.00 9822.30 22982.00 11918.00 NA NA 7401.40 32626.0 15938.00 NA 242760.0 5.5175e+04 4.8702e+05 4169.40 7.0330e+04 51454.00 6.4450e+05 84908.00 64621.00 80336.0 26899.00 43574.0 112360.00 19320.000 24622.00 1.3043e+05 40572.00 232910.00 9.6903e+05 67745.000 122970.00 534110.00 125920.00 8551.8 2.9502e+04 9752.30 4222.30 21472.00 3690.70 54740.00 2722.200 20800.000 11881.00 28151.00 2.1751e+04 36730.00 53707.00 11255.00 73631.00
TWLNPDPSQKQNLLAPQNAVSSEETND 422950.0 NA NA NA 4.6695e+01 NA 32434.00 NA 219.07 NA 6.5198e+04 NA 1611.70 2592.70 15335.0 1.6563e+04 NA 49.858 6608.80 6470.60 19975.00 51261.00 25187.00 4190.400 106.880 696.880 3039.50 1694.400 1915.20 5225.7 17979.00 11243.00 23824.00 1548.00 NA NA NA 38609.00 13170.00 2007.10 12094.00 NA NA NA 694.96 205500.0 598.60 NA 3504.1 2.7849e+04 5.0011e+04 59464.00 4.4431e+04 56037.00 1.3640e+04 15418.00 5904.70 17147.0 NA 42014.0 17332.00 NA 6514.80 NA 6954.60 4368.10 NA 21.686 18709.00 12979.00 5583.10 4121.3 2.1902e+04 9649.30 8770.50 NA 12349.00 2277.50 NA 3020.900 773.87 12739.00 1.5989e+04 682.40 8531.10 26667.00 3030.50
AIPVAQDLNAPSDWDSRGKDSYETSQL 532970.0 4691.80 NA 1732.00 3.4301e+03 1788.90 NA NA 3258.50 NA NA NA 11412.00 4588.70 NA 2.4902e+04 NA 31.486 9642.70 16461.00 11908.00 5855.10 3800.10 2276.700 1248.300 5772.900 1663.90 775.090 NA 6133.8 NA 133930.00 83748.00 NA NA 131.19 NA NA NA 3886.80 17991.00 2525.40 13593.0 NA 1246.20 279230.0 NA 222.62 71155.0 3.3286e+04 2.7833e+04 59450.00 1.4722e+04 39043.00 2.4531e+03 37473.00 14171.00 30060.0 NA 37526.0 6776.40 NA 590.16 5.8061e+03 NA 6494.60 5.7223e+03 1941.100 24740.00 NA 803.31 NA 7.6156e+01 75777.00 3195.70 5722.50 31557.00 NA 690.180 4676.100 1218.20 13509.00 2.4585e+04 155.32 4104.50 10432.00 18349.00
LAQELPQQLTSPGYPEPYGKGQESSTD 63376.0 9439.70 NA 2403.30 NA 531.47 15521.00 NA 5249.20 355.25 2.9661e+04 9643.70 5100.60 11877.00 NA 1.0394e+04 163.62 NA 14925.00 NA 6492.30 7223.90 3902.00 4990.000 1538.000 10385.000 NA 1019.700 5566.70 6930.2 10219.00 16101.00 5069.40 3282.20 NA NA NA 7837.40 3501.10 NA NA 9247.50 16735.0 NA NA 87286.0 NA 5677.80 33778.0 8.1066e+04 3.2113e+04 NA 1.8615e+04 10606.00 1.7181e+04 18212.00 8395.00 13747.0 NA 18077.0 13735.00 1195.200 2720.20 1.0102e+04 NA 2978.00 5.2744e+03 1639.900 20520.00 7467.40 4051.00 6663.6 1.3300e+04 9071.90 12809.00 NA 14615.00 1971.50 2128.800 NA NA 11058.00 1.2658e+04 NA 9900.10 13221.00 7978.60
WLNPDPSQKQNLLAPQNAVSSEETND 268170.0 13497.00 2499.60 NA NA NA 21050.00 NA 33982.00 NA 3.4439e+04 NA 307.98 19002.00 11287.0 9.7101e+03 NA NA 5726.60 9216.30 19105.00 31519.00 16915.00 3073.800 702.530 7096.800 2995.20 1698.800 NA 4897.7 9415.30 7396.50 9670.20 NA NA NA NA 26304.00 9886.90 3299.80 9269.20 1629.40 4520.8 NA NA 140570.0 NA NA NA 1.2450e+03 3.3397e+04 23933.00 1.4177e+04 24294.00 3.2222e+03 8022.50 4377.40 17446.0 2348.10 29489.0 14390.00 NA 3015.70 1.7935e+03 3120.40 2413.10 1.2883e+04 NA 30138.00 9505.40 3956.40 2642.8 1.2666e+04 7964.90 18630.00 NA 9609.00 3413.90 NA 1767.400 1866.70 7606.90 1.3701e+04 NA 4006.00 25719.00 1618.60
IPVKQADSGSSEEKQLYNKYPDAVAT 4505100.0 563290.00 971940.00 53583.00 2.3723e+04 26014.00 141150.00 9955.00 626320.00 132100.00 1.9837e+06 88683.00 50270.00 353560.00 761380.0 5.8922e+05 12525.00 204.440 188590.00 540440.00 583310.00 1053100.00 1160000.00 75998.000 56057.000 355240.000 157370.00 22492.000 313710.00 256150.0 434470.00 504490.00 663110.00 100060.00 8579.200 19136.00 10210.000 945560.00 1264600.00 1191200.00 1217200.00 84262.00 783170.0 24108.000 37764.00 2602900.0 127350.00 77541.00 3695200.0 9.0746e+05 5.5225e+05 919710.00 7.4763e+05 1526400.00 6.3143e+05 340120.00 151020.00 448850.0 151780.00 1198600.0 337930.00 17739.000 62951.00 4.8183e+05 657460.00 92653.00 1.1934e+06 22792.000 638270.00 289860.00 97248.00 638020.0 1.1937e+06 1776500.00 765590.00 1137600.00 1109000.00 178170.00 128520.000 187930.000 149790.00 682940.00 9.4547e+05 69765.00 813570.00 1013600.00 374150.00
EAEDLQVGQVELGGGPGAGSLQPLALEGS NA NA NA NA NA NA 4065.80 NA NA 22069.00 9.5287e+03 7451.30 1843.40 10028.00 33851.0 3.8873e+04 2250.80 387.510 16121.00 2288.90 34814.00 120400.00 29482.00 15176.000 2645.200 30528.000 54024.00 22780.000 2222.40 5361.9 NA 10540.00 3355.30 2071.40 NA 624.69 NA 1270.60 NA NA 726.76 1817.00 NA NA NA NA NA NA NA NA 3.7418e+04 NA NA 1173.00 5.5005e+04 16603.00 10444.00 11621.0 NA NA 19993.00 4526.800 4758.10 1.8293e+04 NA 35069.00 9.1871e+04 12630.000 12627.00 49310.00 15098.00 NA NA NA NA NA NA 9575.70 NA 4596.600 2079.90 NA NA 6430.30 3183.40 NA 4232.70
TAQLDEELGGTPVQSRVVQGKEPAHL NA NA NA 1913.00 NA NA 7994.10 NA NA NA 3.2317e+05 NA NA 16226.00 56349.0 6.0369e+04 NA NA 22892.00 25794.00 46198.00 49372.00 19184.00 4151.900 7149.700 15556.000 NA 1117.900 1445.60 25003.0 105700.00 256800.00 140170.00 49608.00 NA NA NA 51953.00 59546.00 50029.00 NA NA NA NA NA NA NA NA 119280.0 2.1995e+05 8.0709e+04 8862.80 NA 45767.00 1.2331e+05 NA 37464.00 50914.0 NA 118580.0 50538.00 NA 4665.30 NA 8917.60 1658.80 1.6251e+04 NA 86545.00 76806.00 44741.00 614320.0 8.0947e+04 72560.00 NA 10821.00 56599.00 4168.50 NA NA 6620.40 52963.00 8.4062e+04 3338.10 NA 10301.00 51117.00
IPVKQADSGSSEEKQLYNKYPDAVA 7514600.0 22117.00 14934.00 25199.00 1.2838e+04 18009.00 487970.00 3961.40 5050.90 60239.00 4.3524e+06 258300.00 28341.00 107310.00 1036100.0 1.0612e+06 670.04 NA 307380.00 357380.00 863890.00 1641200.00 1656900.00 102030.000 46785.000 42342.000 173430.00 3121.800 469820.00 512550.0 1187800.00 1016900.00 1741500.00 209380.00 770.970 2342.80 1909.500 1993300.00 2346900.00 1058900.00 2054000.00 140160.00 346000.0 757.300 18983.00 4623900.0 21065.00 33531.00 33003.0 1.8040e+06 9.3925e+05 1680700.00 1.7239e+06 2565900.00 1.1807e+06 553690.00 63478.00 562800.0 232460.00 1552100.0 501900.00 38070.000 146420.00 1.2178e+03 1208600.00 240270.00 2.9646e+03 25291.000 705790.00 650190.00 227650.00 1323000.0 2.4252e+06 2929700.00 825940.00 3459600.00 2000900.00 262250.00 250320.000 469180.000 189510.00 1415200.00 1.6106e+06 107540.00 1386000.00 2204700.00 575020.00
AQLDEELGGTPVQSRVVQGKEPAHL 73334.0 NA NA NA NA NA 5813.70 NA NA NA 1.7702e+05 NA NA NA 33716.0 2.3829e+04 NA NA 7764.00 8684.90 21934.00 22826.00 6738.40 2417.500 2539.600 8076.000 NA NA NA 16097.0 60084.00 162510.00 67830.00 30088.00 NA NA NA 25459.00 24730.00 28670.00 NA NA NA NA NA 97249.0 NA NA 98414.0 1.1899e+05 3.6504e+04 11450.00 NA 27957.00 7.7247e+04 NA NA 40972.0 NA 72159.0 28545.00 NA NA 2.2088e+04 1059.00 960.44 1.0511e+04 NA 44778.00 38813.00 21646.00 361890.0 4.1848e+04 47456.00 13766.00 NA 52294.00 NA NA 3868.900 3283.20 18569.00 4.4682e+04 NA NA 9385.70 32188.00
VKQADSGSSEEKQLYNKYPDAVAT 736380.0 160940.00 140870.00 13578.00 1.4067e+04 4992.60 166710.00 10182.00 239020.00 57940.00 1.8406e+05 16923.00 28304.00 181830.00 104720.0 2.6092e+05 2640.60 409.780 86855.00 136270.00 181010.00 559030.00 312810.00 24271.000 18567.000 75211.000 66881.00 21450.000 73543.00 215150.0 179370.00 218160.00 360130.00 60871.00 9861.900 5495.80 6385.800 507650.00 270510.00 269790.00 299860.00 37824.00 219820.0 13232.000 7296.60 407990.0 12137.00 72407.00 469190.0 9.2291e+04 2.4114e+05 244990.00 5.7227e+04 269490.00 1.2098e+04 82781.00 26256.00 172120.0 57982.00 323970.0 179930.00 13299.000 32737.00 1.4015e+05 70348.00 18664.00 2.7961e+05 9716.300 189140.00 63817.00 20285.00 193040.0 4.2983e+05 246150.00 125380.00 76219.00 313730.00 57845.00 96821.000 31323.000 74473.00 316920.00 3.7573e+05 24742.00 178400.00 414160.00 148100.00
LSDPEQGVEVTGQYEREKAGFSW 281250.0 NA 159270.00 544.30 NA 4632.50 39793.00 3479.20 4089.40 NA 6.6311e+05 721.16 NA NA NA 4.8386e+04 NA NA 62062.00 25958.00 19850.00 45619.00 17939.00 1610.200 NA 6179.400 NA NA 9346.50 68874.0 58496.00 109510.00 113710.00 9754.00 NA NA NA 85552.00 182460.00 528670.00 68041.00 9975.30 21491.0 NA 3254.40 509590.0 1096.10 NA 194870.0 2.5873e+05 1.3611e+05 266330.00 8.0843e+04 121780.00 2.3968e+05 NA NA 36428.0 NA 221180.0 24017.00 NA NA 5.0366e+04 27973.00 4810.40 4.9934e+03 NA 85799.00 11394.00 3488.30 222530.0 6.2831e+04 235990.00 21970.00 108470.00 130480.00 NA 455.590 NA 329.17 91657.00 1.5095e+05 10819.00 46640.00 42701.00 85641.00
MVEHTPDEESIDWTKIEPSVNF 140340.0 NA 34786.00 NA NA NA 2023.10 NA 2073.30 NA 2.2961e+05 NA NA NA 56784.0 8.9351e+03 NA NA 11394.00 50361.00 28747.00 37017.00 64411.00 16841.000 NA 8877.100 NA NA 10782.00 13292.0 28321.00 29802.00 48797.00 NA NA NA NA 19676.00 55620.00 84311.00 11432.00 4210.00 10324.0 NA NA 189440.0 NA NA 147860.0 9.3172e+04 5.7480e+04 75165.00 2.1156e+04 61763.00 9.7586e+04 1332.90 NA 35940.0 NA 15825.0 14030.00 NA 12100.00 2.8118e+04 189250.00 2516.20 4.0187e+03 NA 58572.00 32348.00 6108.00 186300.0 3.9987e+04 101480.00 9795.60 41966.00 48609.00 NA NA NA 687.03 37034.00 1.8152e+04 214.15 759.15 9761.10 27098.00
AQDLNAPSDWDSRGKDSYETSQL 6317.4 158540.00 174660.00 8319.90 3.6268e+03 1561.20 NA 1073.50 121530.00 NA 5.4623e+03 NA 1801.20 94819.00 1103.8 6.3677e+03 1873.70 NA 10938.00 58833.00 NA 4405.60 1058.40 NA 10068.000 72435.000 4634.90 NA 21306.00 57120.0 3547.00 147180.00 NA 10698.00 1673.000 908.63 3208.300 5388.40 111050.00 9113.40 2489.20 NA 1358200.0 13338.000 1010.80 75996.0 NA 5293.60 886330.0 2.2466e+04 7.5703e+02 44268.00 NA 15057.00 9.8764e+03 NA NA NA NA NA 42744.00 NA 2640.20 1.3319e+05 NA NA 9.5171e+04 5163.000 25299.00 NA NA 5177.3 NA 6917.70 26832.00 NA 10587.00 NA 8535.500 NA 28664.00 NA 1.0791e+05 8042.10 5481.00 13647.00 75896.00
EDPQGDAAQKTDTSHHDQDHPTF 366970.0 25768.00 63950.00 NA NA NA 10234.00 NA NA NA 1.6735e+05 NA NA NA 67816.0 NA NA NA NA 39455.00 27192.00 10064.00 15882.00 NA 7462.900 27052.000 NA NA 43676.00 79965.0 102350.00 173550.00 119800.00 NA 8443.300 NA NA 42244.00 101500.00 116930.00 92631.00 51624.00 211790.0 8578.800 NA 189110.0 NA NA 256350.0 1.6899e+05 3.9119e+04 267900.00 8.1199e+04 73548.00 NA NA NA NA NA NA 14948.00 NA NA 1.4788e+05 52499.00 5747.80 4.1486e+04 2990.200 26130.00 20495.00 6534.60 171770.0 1.8255e+05 219640.00 123820.00 163270.00 405110.00 16139.00 53472.000 55569.000 NA 223550.00 1.5447e+05 7926.80 136000.00 119160.00 68179.00
IPVKQADSGSSEEKQLYNKYPDA 727430.0 59315.00 NA 11472.00 2.3960e+04 28403.00 88182.00 13291.00 13125.00 12113.00 2.7261e+05 49574.00 NA 5731.10 NA NA NA 2600.900 44672.00 75582.00 93961.00 174740.00 213660.00 23754.000 29696.000 19160.000 17198.00 NA 71078.00 47595.0 196860.00 170420.00 132180.00 38890.00 5358.100 11589.00 NA 331810.00 262260.00 106130.00 252280.00 NA 937750.0 NA 44302.00 502180.0 5619.30 37649.00 116720.0 2.1193e+05 5.0512e+04 350000.00 1.6647e+05 159530.00 6.1674e+04 23468.00 7803.20 43430.0 14227.00 53318.0 69477.00 33429.000 29965.00 3.6910e+03 113810.00 59761.00 1.4723e+04 11381.000 98933.00 76032.00 29490.00 138690.0 1.7768e+05 294050.00 190180.00 414270.00 270350.00 55228.00 65140.000 140300.000 32601.00 120180.00 1.6012e+05 25123.00 213550.00 433430.00 54926.00
LSRQELFPFGPGQGDLELEDGDD 45855.0 NA 13455.00 NA NA NA 4259.50 NA 3763.00 NA 8.2795e+04 NA NA 5284.60 50966.0 2.2824e+04 612.67 NA 16057.00 15511.00 26407.00 34791.00 16132.00 4931.400 NA 9153.300 3481.70 2758.200 1722.70 5062.4 3792.70 17274.00 14807.00 NA NA NA NA 11622.00 12441.00 12840.00 9966.10 NA NA NA NA 26998.0 NA NA 50741.0 3.6383e+04 3.1253e+04 18782.00 1.2704e+04 24770.00 5.1639e+04 NA 4697.80 17557.0 10121.00 42523.0 14400.00 NA 6325.70 1.4252e+04 3119.20 3305.40 2.7979e+04 130.780 5862.60 23436.00 15033.00 32924.0 1.5964e+04 15016.00 NA NA 17634.00 NA NA 1912.100 NA 21568.00 1.0796e+04 367.66 6498.70 NA 25748.00
VKQADSGSSEEKQLYNKYPDAVA 956690.0 8073.40 NA 30033.00 2.1157e+04 10132.00 184690.00 5533.50 NA 58733.00 3.9313e+05 25220.00 29819.00 23250.00 124130.0 2.0072e+05 NA 375.550 89165.00 77320.00 207030.00 746260.00 416230.00 37975.000 13066.000 10109.000 57405.00 35133.000 119150.00 340190.0 418160.00 357200.00 743180.00 142850.00 1259.600 8797.00 4125.000 883230.00 606180.00 183380.00 404420.00 67158.00 63383.0 3302.400 16622.00 505290.0 NA 38252.00 NA 2.0900e+05 2.9197e+05 307740.00 2.2166e+05 326300.00 4.2080e+04 57930.00 12132.00 138720.0 46594.00 188390.0 154030.00 15138.000 72676.00 NA 110190.00 38776.00 2.6304e+03 14065.000 207140.00 69298.00 36129.00 317570.0 7.0823e+05 273960.00 152750.00 206250.00 373690.00 111730.00 142650.000 64783.000 94326.00 498620.00 5.4976e+05 33953.00 335810.00 660610.00 199800.00
EAEDLQVGQVELGGGPGAGSLQPLAL 427710.0 9952.60 21411.00 NA NA 1138.20 6492.00 554.52 214.01 23918.00 1.5282e+05 17874.00 25569.00 22866.00 379490.0 5.1203e+05 517.69 1838.700 210340.00 13161.00 111210.00 322650.00 304480.00 39383.000 12464.000 120960.000 27990.00 12533.000 84178.00 221670.0 45337.00 404000.00 97788.00 18753.00 1792.400 1007.70 2885.000 24906.00 48148.00 101630.00 24812.00 74163.00 NA 4732.500 6225.50 230240.0 NA 2548.30 193240.0 4.6565e+05 2.6664e+05 18363.00 3.6548e+05 122650.00 8.8443e+05 34682.00 45163.00 148620.0 1215.80 48038.0 72996.00 11591.000 2029.60 1.6346e+05 14389.00 21103.00 5.2469e+04 40878.000 636850.00 96411.00 30544.00 55824.0 2.9074e+04 65323.00 94689.00 10372.00 102700.00 28855.00 30873.000 10681.000 13398.00 81388.00 6.8748e+04 23915.00 152300.00 239940.00 158400.00
IAVEWESNGQPENNYKTTPPVL 728840.0 12751.00 980920.00 7978.10 NA 2410.80 21584.00 NA 44277.00 4046.50 4.9533e+05 NA 6255.90 27955.00 186470.0 1.5275e+05 NA NA 224550.00 63245.00 126790.00 215530.00 185450.00 5624.800 3094.900 29311.000 14958.00 168.740 54709.00 86396.0 182330.00 191530.00 146730.00 12568.00 NA NA NA 76291.00 128930.00 282180.00 267790.00 35506.00 53039.0 463.710 1459.20 694710.0 NA 5738.20 528720.0 5.1166e+05 1.8280e+05 290580.00 2.1542e+05 24560.00 1.6930e+05 14947.00 5678.40 200040.0 95320.00 149280.0 56749.00 NA NA 3.9439e+05 15650.00 1475.90 1.1852e+04 4132.000 175470.00 41245.00 13797.00 129760.0 8.0537e+04 185280.00 45060.00 34876.00 299080.00 556.24 4457.200 10184.000 2468.90 310540.00 3.3169e+05 264.77 64374.00 49562.00 246330.00
AKADAAPDEKVLDSGFREIENK 93540.0 NA NA NA NA NA NA NA NA NA 8.9283e+04 NA NA NA NA 4.6485e+04 NA NA 23485.00 25290.00 24519.00 NA NA 3876.500 NA 13796.000 NA NA 25429.00 71211.0 13306.00 68906.00 41970.00 NA NA NA NA 42454.00 44046.00 NA 45664.00 11649.00 NA NA NA 143580.0 NA NA 223790.0 8.7325e+04 5.4980e+04 194080.00 NA NA 3.8266e+04 NA NA 24882.0 NA 97184.0 NA NA NA 3.9066e+04 85727.00 5342.00 1.0366e+04 NA 20824.00 10171.00 1371.40 114370.0 1.2114e+05 183270.00 NA 157570.00 76350.00 5671.10 5788.700 NA NA 90584.00 5.4200e+04 NA 62956.00 50658.00 68824.00
FKQETLPSKSNESHDHMDDM 310380.0 NA NA NA NA NA 65476.00 NA 18767.00 26117.00 1.3477e+05 6904.70 22125.00 46455.00 NA NA NA NA NA 39000.00 38084.00 111960.00 71342.00 27357.000 12807.000 25786.000 39731.00 4294.300 57343.00 35950.0 142300.00 92480.00 62809.00 34323.00 NA 6639.90 NA 124110.00 188170.00 274730.00 175070.00 18527.00 453910.0 NA 13814.00 235740.0 NA 28943.00 NA 1.7247e+05 9.0478e+04 147590.00 6.0693e+04 92931.00 6.2072e+04 84476.00 20551.00 63163.0 42986.00 NA 39906.00 12805.000 32734.00 NA 39182.00 21082.00 2.8509e+03 NA 101960.00 37708.00 17996.00 123450.0 1.4425e+05 78734.00 199830.00 278730.00 186320.00 22302.00 53710.000 40393.000 15602.00 38070.00 2.0893e+05 17006.00 NA 392790.00 7297.80
DEELGGTPVQSRVVQGKEPAHL 706130.0 46434.00 129270.00 49938.00 2.0876e+04 849.10 32110.00 NA 83014.00 NA 5.5288e+05 39691.00 18246.00 48162.00 62122.0 1.1053e+05 NA NA 84305.00 56539.00 84175.00 73835.00 39623.00 18306.000 56726.000 41965.000 NA 5409.300 47893.00 177040.0 614550.00 1213000.00 500680.00 228230.00 6322.000 NA 3196.000 187450.00 295940.00 313170.00 83143.00 71405.00 1118500.0 12032.000 NA 679450.0 NA 23568.00 173740.0 1.1789e+06 1.6595e+05 NA NA 200270.00 3.1506e+05 14537.00 58144.00 112590.0 22976.00 369110.0 121940.00 NA 10666.00 1.1870e+05 NA 7641.60 3.0803e+04 6852.800 412400.00 106000.00 55513.00 2382500.0 2.5334e+05 391750.00 171720.00 59392.00 826340.00 24799.00 65973.000 29537.000 43200.00 148790.00 3.6660e+05 25072.00 78202.00 159180.00 201450.00
LSDPEQGVEVTGQYEREKAGF 579860.0 15392.00 262550.00 NA NA NA 45950.00 928.45 12890.00 13590.00 9.0362e+05 864.90 1455.50 NA 167100.0 4.4835e+04 NA NA 255550.00 48927.00 26694.00 44677.00 21560.00 2172.900 1956.800 26830.000 NA NA 124620.00 760570.0 568380.00 773180.00 740290.00 75303.00 1563.600 NA 5030.700 281130.00 911890.00 449480.00 218700.00 92010.00 417230.0 7700.600 NA 1467600.0 NA 4032.90 366400.0 1.1325e+06 1.8133e+05 147660.00 2.6394e+05 147020.00 3.1606e+05 6632.20 32596.00 68290.0 24423.00 502190.0 80336.00 10922.000 2487.80 2.0242e+05 NA NA 2.4494e+04 2367.300 495810.00 16292.00 9182.10 626550.0 8.0992e+04 184650.00 89524.00 33418.00 580250.00 36513.00 80628.000 27706.000 23461.00 137010.00 1.4387e+06 19113.00 609820.00 611560.00 265520.00
LNAPSDWDSRGKDSYETSQL 211730.0 14355.00 NA 7874.30 8.6207e+03 8452.50 49981.00 NA NA 24556.00 3.1788e+04 23067.00 25489.00 25047.00 13325.0 5.3239e+04 NA 1511.300 21306.00 24548.00 20955.00 16760.00 28833.00 11365.000 8599.900 12652.000 8423.10 4826.500 28554.00 37672.0 75408.00 58531.00 41575.00 16113.00 2472.700 NA NA 139920.00 90812.00 98046.00 65162.00 15767.00 92930.0 NA 8334.90 157120.0 NA 22096.00 NA 7.6804e+04 6.2586e+04 104920.00 4.6646e+04 37527.00 2.4292e+04 162760.00 18513.00 30836.0 27646.00 33634.0 21399.00 10470.000 13014.00 NA 7828.20 18165.00 NA 8299.500 71975.00 15959.00 11494.00 53502.0 6.7868e+04 87598.00 48009.00 95732.00 180080.00 15877.00 36459.000 32864.000 13519.00 54045.00 5.8833e+04 9355.20 66342.00 198900.00 32050.00
FKQETLPSKSNESHDHMDD 186640.0 NA NA 27978.00 NA NA 26043.00 NA NA NA NA NA NA NA NA 8.6073e+04 NA NA NA 34883.00 NA 54316.00 48329.00 17052.000 9700.600 20205.000 NA NA 32574.00 29627.0 87320.00 38538.00 14602.00 21203.00 NA NA NA 86658.00 113710.00 190890.00 95732.00 10203.00 255120.0 NA 8081.60 182530.0 NA NA 95750.0 1.2480e+05 7.6016e+04 103200.00 NA 142820.00 NA NA NA 46499.0 NA NA 28023.00 5598.900 11493.00 NA 20960.00 14929.00 5.1372e+03 NA 79084.00 19737.00 5028.20 43243.0 6.2233e+04 46033.00 156960.00 91073.00 93081.00 NA NA 17164.000 11081.00 29335.00 7.5043e+04 NA 91088.00 200600.00 NA
EAEDLQVGQVELGGGPGAGSLQP NA 14692.00 NA NA NA NA 23003.00 732.93 NA 4114.70 NA 4577.50 20014.00 17506.00 NA 3.1139e+03 10147.00 4745.100 18174.00 NA 3796.10 8935.60 2450.20 12850.000 14329.000 27079.000 10168.00 21938.000 13270.00 34417.0 13336.00 67201.00 3791.30 4223.40 2233.300 2349.00 7947.600 1062.60 6719.10 NA 2430.60 NA NA 3369.100 9496.00 NA 4841.30 1910.20 NA 1.9829e+04 NA NA 1.9546e+04 NA NA 1245.10 40822.00 NA NA NA 28462.00 22021.000 1090.20 6.8771e+03 NA 21369.00 6.5092e+04 14151.000 32107.00 4691.30 9978.00 NA NA NA 7530.20 NA NA 13208.00 5510.100 2630.300 9119.20 NA NA 16253.00 6894.10 15382.00 3295.80
LVLTGYQVDKNKDDELTGF 139770.0 27115.00 1270100.00 21318.00 5.7324e+03 6058.10 89395.00 NA 332930.00 1984.00 2.7709e+05 19160.00 12347.00 47625.00 83025.0 5.2862e+04 NA 905.750 73709.00 26658.00 10807.00 23866.00 55736.00 21593.000 13572.000 12268.000 11033.00 30958.000 49107.00 37155.0 97065.00 173750.00 56470.00 14991.00 1387.000 3617.10 NA 64313.00 69104.00 48533.00 21365.00 24603.00 56008.0 NA 4092.50 173810.0 14739.00 1342.70 224660.0 3.2117e+05 7.3838e+04 84294.00 NA 75264.00 NA 30719.00 91147.00 38806.0 9272.90 210470.0 68399.00 7851.300 26734.00 6.2733e+04 11655.00 145450.00 1.3402e+04 11607.000 42016.00 25134.00 19474.00 48070.0 6.0022e+04 3017.90 114560.00 5921.90 56016.00 20509.00 11818.000 53631.000 15808.00 37818.00 2.0632e+04 22433.00 16822.00 28034.00 14875.00
VQVFAPANALPARSEAAAVQP 50972.0 22034.00 18122.00 7161.70 2.2804e+02 8166.80 61027.00 568.33 70501.00 47477.00 6.1074e+04 18154.00 26793.00 39274.00 17174.0 2.3182e+04 349.87 NA 74302.00 42753.00 41961.00 39554.00 30191.00 35292.000 4451.300 141860.000 30750.00 11809.000 18710.00 12416.0 986.14 1883.20 2763.50 3902.30 NA 1898.80 3127.600 9109.70 12499.00 8866.70 17549.00 10518.00 NA 2063.500 5257.80 76239.0 57239.00 26325.00 69303.0 7.7898e+04 8.4458e+04 6275.30 3.5548e+04 16232.00 1.3253e+05 109050.00 66720.00 171840.0 19826.00 150740.0 46940.00 163.670 23747.00 7.4380e+04 13112.00 21215.00 1.7143e+04 11978.000 86910.00 29606.00 31097.00 10790.0 2.7863e+04 8430.30 22958.00 NA 1743.70 9696.40 4376.200 13571.000 7661.90 26201.00 2.1425e+04 7949.00 27728.00 9322.80 10186.00
DGQPGAKGEPGDAGAKGDAGPPGP 44355.0 NA NA 14054.00 3.9307e+02 39535.00 4572.80 2341.70 35866.00 24706.00 2.9086e+04 NA 4045.80 5418.60 NA 4.7078e+03 3732.10 NA NA NA 68687.00 63837.00 23716.00 2847.800 NA NA 75456.00 21739.000 NA 107250.0 NA 59332.00 1306.40 29916.00 2335.700 28624.00 622.680 NA NA 70741.00 NA NA NA 544.420 7292.80 81660.0 NA 7555.00 NA NA 1.0117e+05 9085.50 NA NA NA NA NA 5060.4 NA NA 17155.00 26513.000 77491.00 3.3656e+04 NA NA 2.3680e+04 NA 65937.00 51570.00 6922.00 NA 1.3931e+05 NA 37630.00 NA NA 18904.00 NA 13756.000 30096.00 90447.00 8.0538e+04 24971.00 1459.70 56144.00 87525.00
IILEHHVAQEPSPGQPSTF 123960.0 7302.40 NA 2619.60 NA NA 13025.00 NA 7973.90 NA NA 4522.50 NA 3606.90 NA NA NA NA 24221.00 7539.30 26436.00 23321.00 8490.60 62.161 1367.700 14357.000 603.39 NA 18672.00 23053.0 17035.00 36104.00 12428.00 9285.80 NA NA NA 19511.00 38415.00 38020.00 41066.00 8383.50 53440.0 NA NA 134310.0 NA NA 111510.0 5.7474e+04 4.7575e+04 8970.10 NA NA 1.1894e+05 5679.40 12970.00 30126.0 NA 83185.0 17861.00 NA 3842.30 1.3583e+04 NA NA 8.2002e+03 1917.200 22523.00 22735.00 8505.60 61066.0 3.8456e+04 44151.00 31378.00 6998.80 50421.00 NA 12391.000 12815.000 4757.80 39414.00 4.3275e+04 NA 21720.00 25805.00 27209.00
DAHKSEVAHRFKDLGEEN 1524300.0 63262.00 2830200.00 104440.00 7.4449e+04 49226.00 2879.20 NA NA NA 2.3056e+06 NA 22456.00 NA 2079800.0 2.8772e+05 NA NA 670780.00 NA 232150.00 59687.00 1724.40 1397.800 NA 70654.000 NA 239.910 270330.00 288950.0 1029600.00 377160.00 1005000.00 42136.00 39161.000 48596.00 NA 73570.00 992410.00 1998900.00 203700.00 39334.00 9415800.0 178900.000 9156.00 437450.0 970.85 75092.00 3430200.0 7.9168e+05 4.9062e+05 844880.00 6.9124e+05 160300.00 1.4001e+06 NA 616880.00 2454500.0 NA 1796000.0 NA NA NA 7.9055e+06 143370.00 32026.00 8.4083e+04 1488.300 264140.00 5981.40 NA 1765400.0 7.0611e+05 2653300.00 551790.00 507850.00 701590.00 53112.00 266440.000 73076.000 NA 2072700.00 1.4585e+06 54112.00 556310.00 921200.00 83201.00
S(+42.01)ETAPAAPAAPAPAEKTPVKK 115300.0 21713.00 NA 29536.00 6.0271e+03 14315.00 51065.00 3126.30 31603.00 45983.00 1.2527e+05 NA 6543.00 24224.00 84364.0 NA 4471.60 774.380 50652.00 45367.00 81514.00 108930.00 50855.00 19625.000 9745.500 37572.000 40826.00 16138.000 62205.00 74010.0 45152.00 112540.00 58429.00 23533.00 5568.900 15773.00 1974.100 60628.00 138110.00 54841.00 57255.00 27214.00 132220.0 8035.300 5547.70 87860.0 22292.00 10670.00 89368.0 1.0002e+05 6.6935e+04 23576.00 7.1948e+04 72693.00 8.0015e+04 NA 19549.00 35592.0 NA NA 35478.00 6126.100 22009.00 2.7400e+04 93813.00 18691.00 4.7770e+04 8750.300 63033.00 74741.00 11759.00 158940.0 1.0446e+05 154880.00 24270.00 91999.00 74074.00 28960.00 11739.000 19688.000 36436.00 96739.00 5.5263e+04 26968.00 53695.00 NA 130810.00
VVVKLFDSDPITVTVPVEV 130880.0 242.08 3273.20 NA NA 826.57 6542.70 931.95 4207.20 37029.00 1.8425e+04 13069.00 121.49 NA 181340.0 1.4833e+05 NA NA 18508.00 58260.00 72560.00 27206.00 8017.40 2760.400 98.329 5321.700 8268.80 511.460 NA NA NA 405.36 1267.40 295.40 NA NA NA NA NA 4166.00 2453.50 373.56 NA NA 386.67 99468.0 NA NA 47036.0 4.1038e+04 5.4619e+04 44124.00 4.9396e+04 188160.00 1.2184e+04 2898.70 52261.00 17635.0 52629.00 84631.0 2233.30 55.058 1747.40 1.3429e+03 50285.00 11404.00 2.4751e+04 1242.600 25671.00 21821.00 10536.00 6572.1 5.4765e+03 2004.70 179.24 3456.60 5461.30 NA NA NA NA 23114.00 5.5545e+03 272.29 838.49 2323.30 3345.90
S(+42.01)ETAPAAPAAAPPAEKAPVKK 86906.0 18072.00 NA 22565.00 4.0217e+03 5116.80 38989.00 1689.80 15612.00 40878.00 1.1325e+05 40893.00 5610.50 5647.70 NA NA 4218.90 989.280 15633.00 31069.00 53390.00 68191.00 45160.00 14565.000 5611.900 28648.000 28267.00 10466.000 41770.00 53217.0 39148.00 NA 20059.00 18911.00 3868.700 11505.00 1737.200 39996.00 89792.00 48795.00 38636.00 17995.00 60991.0 6186.900 2700.70 57519.0 16493.00 7228.70 54077.0 9.1392e+04 4.5768e+04 17142.00 6.8093e+04 62624.00 NA NA NA 25890.0 NA NA 24008.00 4140.300 15569.00 1.6866e+04 47434.00 14522.00 3.4615e+04 6383.900 39875.00 48663.00 7327.20 123550.0 7.6463e+04 112950.00 15318.00 82520.00 50430.00 17310.00 10713.000 15688.000 22762.00 64938.00 3.6936e+04 17561.00 40192.00 30112.00 85701.00
VLTGYQVDKNKDDELTGF 191260.0 163600.00 1368300.00 68147.00 2.8647e+04 12947.00 76884.00 6113.00 457820.00 42300.00 2.0835e+05 14483.00 48547.00 106680.00 112090.0 4.9812e+04 5805.40 16028.000 233040.00 52336.00 6303.60 31589.00 76671.00 47586.000 55537.000 60935.000 24429.00 37795.000 225110.00 109980.0 121900.00 173770.00 109350.00 32962.00 43211.000 61484.00 13210.000 70787.00 139710.00 62875.00 53031.00 124360.00 245380.0 34016.000 27409.00 215520.0 43270.00 36551.00 191690.0 4.4945e+05 1.0063e+05 17129.00 2.4174e+03 NA NA 94727.00 207400.00 127520.0 59502.00 286430.0 106560.00 75277.000 47993.00 1.2537e+05 12117.00 262370.00 4.5186e+03 51933.000 100690.00 15829.00 37800.00 90756.0 9.9084e+04 2804.70 418780.00 1008.00 115820.00 62466.00 158630.000 132450.000 76450.00 45298.00 7.5111e+04 53518.00 67636.00 119350.00 25545.00
KANDESNEHSDVIDSQEL 242990.0 22290.00 NA 4327.20 5.4218e+03 NA 14927.00 2497.20 5655.80 NA NA 2288.40 NA NA NA 8.3126e+03 NA 3890.900 20143.00 13622.00 6997.40 21652.00 23161.00 12392.000 9026.100 16939.000 NA NA 40750.00 33622.0 53992.00 54032.00 59128.00 12688.00 NA NA 2498.700 28161.00 49420.00 NA 59907.00 16112.00 66622.0 3913.900 7051.20 103620.0 NA 7263.90 29404.0 2.7679e+04 1.2944e+04 14314.00 NA 8301.00 NA 21655.00 7231.60 10693.0 1676.20 NA 24060.00 9025.900 NA 8.3740e+03 NA 7930.80 NA 8259.000 51955.00 5739.50 7089.50 18191.0 2.0662e+04 33072.00 61773.00 2996.00 53910.00 10160.00 41652.000 21121.000 12146.00 NA 7.6548e+04 6588.00 86662.00 251870.00 NA
ASHTSDSDVPSGVTEVVVKL 11270.0 NA NA NA NA NA 5700.80 NA NA NA NA NA NA 17643.00 22996.0 2.0477e+04 NA NA 13554.00 29504.00 40403.00 32844.00 8961.20 5466.800 NA 8837.200 17478.00 5213.400 3340.00 4890.3 10009.00 NA NA 2764.60 NA NA NA NA 11869.00 NA 8279.50 3363.30 NA NA NA 12889.0 NA NA 26884.0 NA 1.2266e+04 NA NA NA NA NA 14349.00 14909.0 NA NA 4174.60 913.580 10006.00 2.3298e+04 2597.30 9438.20 3.5875e+04 3065.200 19750.00 22902.00 8660.30 5183.7 NA NA NA NA NA 1475.80 NA 6729.700 710.35 NA 1.1709e+04 2415.90 2064.30 6760.00 2438.60
AKVQWKVDNALQSGNSQE 1083500.0 41445.00 111090.00 41204.00 1.9998e+04 37350.00 156150.00 10837.00 37057.00 59272.00 1.0761e+05 27823.00 9245.20 10330.00 2985.4 1.9892e+05 NA NA NA 5017.70 NA NA 7788.00 NA NA NA NA 129.310 795.51 4695.0 67010.00 242780.00 40557.00 8991.00 2134.100 1396.30 6363.500 21705.00 9895.20 46223.00 10608.00 10392.00 2862800.0 200360.000 69231.00 717770.0 8982.50 39738.00 186640.0 1.5758e+06 5.9436e+03 152490.00 NA 6390.00 5.9372e+04 NA 14700.00 53241.0 NA 155430.0 3797.90 NA NA NA NA NA NA 513.960 26100.00 1898.00 NA 403380.0 2.6230e+05 299900.00 94112.00 218090.00 458700.00 51688.00 12539.000 42731.000 15888.00 32013.00 4.3574e+04 13164.00 16214.00 67601.00 21232.00
VFEIGSPATTNGVVPADVIL 34847.0 NA 217.78 112.83 NA NA 668.09 NA NA NA 1.4896e+04 NA NA 345.39 4352.3 1.4291e+03 NA NA 10677.00 NA 434.71 2084.10 2791.60 1334.300 230.130 NA NA NA 533.93 1191.7 1255.30 8496.40 3869.80 NA NA NA NA 1016.90 1967.30 610.77 NA 1734.20 3118.6 NA NA 50685.0 NA NA 7093.7 6.6435e+04 4.0369e+03 12159.00 1.3592e+04 12414.00 2.1140e+04 2156.70 1196.00 7018.0 NA 9627.3 5044.00 NA NA NA NA NA NA NA 16190.00 961.93 1825.90 7811.9 NA NA 1224.70 NA 8953.60 NA NA NA NA 2635.40 3.0445e+03 NA 1687.50 6157.70 7290.10
PSDWDSRGKDSYETSQL 180360.0 14124.00 NA 9220.80 8.6345e+03 8257.10 16477.00 3153.60 NA NA NA NA 18144.00 14222.00 NA 1.3583e+04 NA 1048.200 6582.00 10186.00 NA 12000.00 20198.00 NA 5899.000 8051.200 3755.20 1877.500 33251.00 24323.0 15890.00 9164.10 20313.00 6670.90 NA 3893.90 569.320 37017.00 64331.00 34835.00 39423.00 14118.00 196440.0 1127.900 NA 133830.0 NA 23407.00 7396.5 8.9491e+04 1.8370e+04 57460.00 3.5920e+04 8830.90 1.0965e+04 30553.00 5303.90 13767.0 NA 10681.0 11203.00 8949.400 4347.90 NA NA 2423.40 1.0528e+03 3204.400 35746.00 2905.20 1437.30 50165.0 1.5375e+04 47116.00 25994.00 22350.00 158200.00 10057.00 37588.000 8698.900 4488.10 17401.00 6.5990e+04 2665.00 69669.00 177530.00 8231.40
FAEEKAVADTRDQADGSR 252750.0 41399.00 94262.00 22491.00 NA 22184.00 35159.00 3911.70 42269.00 26206.00 1.7057e+05 NA 9828.30 56055.00 121950.0 1.0226e+05 5493.20 NA 57040.00 80693.00 88673.00 119290.00 19833.00 51874.000 6906.300 17043.000 NA 863.000 86085.00 124690.0 66206.00 153070.00 100170.00 46315.00 2032.200 NA NA 134100.00 61237.00 NA 120100.00 44991.00 NA 9791.700 13351.00 147580.0 29438.00 25205.00 254530.0 NA 1.3604e+05 97235.00 3.1493e+04 31956.00 6.5282e+04 29188.00 NA 83476.0 NA 160380.0 16581.00 NA 37733.00 7.3437e+04 NA 68883.00 3.8547e+04 4734.200 74337.00 24397.00 8887.90 54557.0 1.5346e+05 NA 137090.00 54606.00 149920.00 56358.00 9699.200 44328.000 37397.00 NA 9.8578e+04 NA 46053.00 28936.00 NA
VVKLFDSDPITVTVPVEV 29172.0 NA NA NA NA NA NA NA 508.34 6829.40 8.2668e+03 NA NA NA 32952.0 2.4451e+04 NA NA 9655.20 17727.00 16755.00 17429.00 4591.40 634.470 169.350 1286.100 2250.40 NA NA NA NA NA NA NA NA NA NA 506.35 NA NA NA NA NA NA NA 36673.0 NA NA 33073.0 1.9887e+04 1.5375e+04 11390.00 2.3185e+04 38560.00 5.5095e+03 607.97 5915.60 8567.2 NA 25488.0 1604.60 NA 1017.90 3.0682e+03 7251.10 1091.70 6.8740e+03 NA 6248.50 4183.80 2888.80 4847.9 1.6881e+03 NA 366.02 NA 2882.90 NA NA NA NA 5630.70 1.3095e+03 NA 1069.60 628.75 1493.80
QVGQVELGGGPGAGSLQPLAL 36525.0 3791.40 NA NA 3.9226e+02 131.25 1535.10 NA NA NA NA NA 6637.10 NA 4938.9 1.4849e+03 NA 277.550 10286.00 NA 265.53 2098.40 3023.60 1328.400 1601.100 3107.100 NA 227.610 912.74 2833.1 NA 8680.20 NA NA NA NA NA NA NA 3818.20 NA 2251.60 16990.0 NA NA 25683.0 NA 2903.30 6628.6 1.0320e+05 NA NA 2.4306e+04 NA 3.3518e+04 NA 4934.00 11335.0 NA NA NA 701.570 NA 2.2897e+03 NA 167.08 NA 617.210 37266.00 110.41 NA 2347.5 NA 1529.50 5088.20 NA 9513.20 NA 829.490 NA NA 992.19 3.3007e+02 NA 974.59 8540.20 2098.90
S(+42.01)ETAPAAPAAPAPAEKTPVK 1725.6 NA NA NA NA 1140.20 NA NA NA NA NA NA NA 398.99 1394.8 NA 2482.80 1353.700 5903.20 9605.40 12411.00 13455.00 2002.00 4459.900 4534.200 16428.000 11844.00 15594.000 10583.00 12149.0 4160.90 13220.00 5760.20 8351.00 2630.200 5907.40 2161.000 6385.70 9606.10 4486.40 6135.90 7500.30 NA 3805.600 NA NA NA NA NA NA NA NA NA 7694.70 3.8564e+03 9407.10 11873.00 10753.0 NA NA 16098.00 7997.300 12514.00 8.0944e+03 NA 10304.00 2.4394e+04 5251.300 8575.00 10539.00 6269.60 1685.7 NA 4163.40 13423.00 2459.70 4026.90 9253.60 6159.800 6972.000 6101.80 3846.60 6.9334e+03 8419.90 9736.10 5448.60 NA
VSEDPINDGEWHRVTAL 240700.0 NA 50336.00 NA NA NA NA NA NA NA 1.7696e+04 NA NA NA 12389.0 9.5520e+03 NA NA 18162.00 22522.00 17593.00 6000.00 8515.90 939.930 1998.300 NA NA NA 12613.00 19393.0 18398.00 86221.00 45403.00 7310.10 NA NA NA 26660.00 38368.00 156640.00 21465.00 14887.00 288890.0 NA NA 295590.0 NA 872.78 22055.0 8.5882e+04 1.2129e+04 9152.20 5.4244e+03 NA 3.9968e+03 NA NA 5471.7 NA 27495.0 4811.70 NA NA 1.1270e+04 23596.00 NA NA 220.340 81938.00 6199.70 331.22 63777.0 2.1945e+04 94980.00 29440.00 11856.00 256710.00 NA 32409.000 NA NA 30361.00 3.2955e+04 NA 11492.00 25530.00 35997.00
FRTQTAPGGQGAPWAEEL 243150.0 2776.90 126750.00 2325.50 NA NA 2397.70 NA NA 657.14 2.6767e+05 NA NA 12626.00 20299.0 1.4917e+05 NA NA 68423.00 32707.00 88473.00 75295.00 39068.00 4298.700 956.590 5846.500 NA 68.441 15353.00 49134.0 44999.00 89070.00 29904.00 9384.40 NA 907.65 97.276 65153.00 109300.00 122220.00 90435.00 16661.00 203280.0 NA NA 449490.0 NA 3615.60 269410.0 2.2154e+05 1.5919e+05 201050.00 1.1252e+03 5658.00 1.2556e+04 NA 423.20 17272.0 2197.30 166620.0 35196.00 436.010 3575.10 5.6742e+04 70499.00 893.56 5.0376e+03 NA 37767.00 31093.00 1242.50 118290.0 8.2230e+04 202710.00 32183.00 62293.00 220070.00 1356.00 2743.300 2884.000 1413.30 100570.00 1.0700e+05 3080.60 37090.00 49224.00 98370.00
SGSVIDQSRVLNLGPITR 7197300.0 277630.00 3308000.00 92411.00 8.8040e+04 56884.00 592740.00 27623.00 815310.00 2567100.00 8.5654e+06 1293700.00 331490.00 570000.00 21320000.0 9.5266e+06 1063.00 1398.200 190110.00 499680.00 1433500.00 2290500.00 3083600.00 19231.000 971.670 43854.000 767200.00 26428.000 308090.00 459940.0 1185600.00 1827800.00 531430.00 118170.00 NA NA NA 2575200.00 1481500.00 1475000.00 1099600.00 32868.00 NA NA 155010.00 7971000.0 346210.00 177010.00 9972900.0 5.6481e+06 6.8850e+06 5336500.00 1.7052e+07 7688700.00 2.1374e+07 1753800.00 3794500.00 2815700.0 5164000.00 24578000.0 43033.00 NA 114870.00 2.5240e+05 4150900.00 37197.00 1.2492e+05 NA 135430.00 1958100.00 59323.00 878140.0 2.5178e+06 978050.00 449580.00 906160.00 663760.00 259340.00 NA 33264.000 100060.00 1784200.00 1.3811e+06 103160.00 1087400.00 1134200.00 654980.00
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IPGGLSEAKPATPEIQE NA 35536.00 103710.00 10760.00 1.6772e+04 2468.10 5142.20 2381.20 42183.00 NA NA 26905.00 7415.10 6451.20 NA NA 1208.20 4938.800 887.84 NA NA NA NA 3715.000 7257.600 2067.600 NA 2535.100 12095.00 3297.2 NA 4042.90 2064.10 826.33 5153.200 1978.90 1385.600 2457.70 NA NA NA 6074.70 9520.0 5056.000 15707.00 NA NA 3241.10 NA 6.7089e+03 NA NA 8.5350e+03 NA NA 13030.00 47476.00 NA NA 6471.4 2984.40 2664.600 1684.70 NA NA 6756.90 1.7199e+03 3888.000 NA NA 1075.30 NA 1.1939e+04 NA 57161.00 NA 6356.20 NA 5674.600 11749.000 2788.70 NA NA 3037.80 2364.70 8285.40 NA
FRVVAQGVGIPEDSIF 309970.0 NA 228880.00 5356.90 2.0884e+03 2693.20 19517.00 NA 40646.00 13311.00 2.9158e+06 57698.00 13928.00 21594.00 130280.0 7.6027e+04 NA NA 114020.00 10292.00 9583.30 8635.20 24628.00 4342.200 304.650 4684.300 NA NA 1397.20 17642.0 154860.00 168670.00 80758.00 6057.70 NA NA NA 67260.00 61714.00 60329.00 4159.50 11150.00 79053.0 NA NA 668490.0 NA 1849.70 202020.0 5.4780e+05 9.6553e+04 127680.00 3.5914e+05 357790.00 3.9708e+05 41224.00 37975.00 166020.0 157160.00 365480.0 3164.40 NA 1108.30 2.5913e+04 557.18 259.59 2.4527e+03 NA 62655.00 16032.00 22162.00 191600.0 3.6387e+04 27105.00 30158.00 44613.00 78652.00 4501.50 58.858 NA NA 69357.00 6.0550e+04 3060.50 28886.00 43196.00 18055.00
VDISQDNALRDEMRA 101170.0 58322.00 NA 37590.00 1.1535e+04 11740.00 34065.00 NA 59887.00 NA 1.1406e+05 NA 23495.00 39222.00 NA NA NA 267.940 17825.00 13968.00 7701.70 12770.00 9326.90 32130.000 36174.000 42879.000 NA 3295.800 49173.00 87171.0 218190.00 217820.00 156890.00 38422.00 12069.000 1942.60 12525.000 55415.00 53954.00 50266.00 13831.00 58595.00 197740.0 12910.000 4095.00 177310.0 NA 46407.00 47093.0 5.9339e+05 3.8426e+04 NA NA NA 5.9364e+04 22199.00 NA 83627.0 NA 33373.0 70966.00 15267.000 10610.00 NA 2006.20 5501.30 1.0467e+04 20698.000 178320.00 16705.00 23077.00 172980.0 3.7444e+04 NA 80149.00 NA 113220.00 9029.60 70916.000 22160.000 30592.00 12141.00 9.6467e+04 11459.00 13246.00 69629.00 29950.00
SEDPINDGEWHRVTA 48802.0 675.24 NA 1142.20 NA NA NA NA NA NA 2.4440e+04 1523.30 1228.40 NA NA 1.0326e+04 613.97 NA 6766.30 14949.00 NA NA 7002.70 1416.600 2522.400 NA 390.63 151.940 6680.90 25296.0 61323.00 129160.00 58028.00 23045.00 93.923 NA 1203.200 25749.00 21946.00 30726.00 14441.00 12650.00 80303.0 NA NA 138490.0 NA NA 9526.7 5.6739e+04 1.4080e+04 NA NA 7579.20 NA NA 919.22 NA NA NA 13294.00 4410.600 3244.90 NA NA NA 8.4038e+02 NA 14462.00 383.70 6356.80 13398.0 NA 22275.00 16066.00 NA 63258.00 4808.40 8394.200 2315.200 5928.50 9927.30 3.4267e+04 2677.20 NA 16643.00 17368.00
LWQGVEVGEAGQGKDF 64695.0 NA 141750.00 NA NA NA NA 695.72 4151.10 12208.00 NA NA NA NA 27243.0 2.4248e+04 NA NA 30813.00 12054.00 4639.10 5478.80 5068.70 3874.200 2477.800 4645.000 NA NA 8273.60 29396.0 42393.00 100640.00 73641.00 17913.00 NA 292.03 NA 25669.00 24263.00 34675.00 12855.00 6442.20 7672.0 390.760 NA 229570.0 NA 132.47 75486.0 9.8844e+04 4.3332e+04 NA 1.5763e+04 NA 3.3442e+04 NA 14841.00 30530.0 6445.90 28948.0 26957.00 903.210 NA 3.3713e+04 NA NA NA NA 41177.00 4154.90 5800.20 21571.0 1.9595e+03 10777.00 8469.60 NA 35197.00 1610.30 5507.100 NA 7642.60 10287.00 3.1913e+04 2296.60 7372.80 15587.00 18573.00
IPVKQADSGSSEEKQL 127040.0 19146.00 20914.00 NA 1.5968e+04 17391.00 NA 10778.00 NA 6716.40 4.4676e+03 NA 14722.00 11350.00 NA NA NA 6969.000 14118.00 NA 8410.10 15190.00 8114.80 11776.000 15178.000 8060.100 1779.30 3481.600 6632.10 23407.0 27006.00 19390.00 NA NA 8730.800 12244.00 10737.000 7836.50 13218.00 NA 35764.00 12738.00 214810.0 NA 17321.00 105190.0 1970.30 24552.00 NA 5.8936e+04 NA NA NA 6307.10 NA NA 24466.00 35341.0 NA NA 17174.00 16865.000 2877.70 2.7206e+03 3373.30 9148.10 NA 8027.200 42872.00 2088.20 6301.60 NA NA 17033.00 156240.00 NA 73213.00 NA 49600.000 29704.000 5268.80 NA 3.3430e+04 5784.00 35824.00 113800.00 NA
VQVFAPANALPARSEAA 19987.0 68188.00 28887.00 41086.00 1.8544e+04 31516.00 36297.00 11776.00 37262.00 30826.00 9.2540e+03 21025.00 40599.00 29094.00 NA NA 14009.00 31163.000 44098.00 16858.00 3555.70 2406.30 NA 23584.000 28291.000 65608.000 5792.60 12994.000 31380.00 25015.0 13185.00 10181.00 8089.10 4355.70 7439.700 6129.90 6746.000 5642.00 14631.00 7292.30 19035.00 18271.00 26226.0 7203.500 31161.00 49356.0 20968.00 75468.00 17097.0 5.8114e+04 1.0738e+04 NA NA NA 2.7165e+04 52820.00 63416.00 114560.0 69258.00 29161.0 35014.00 50988.000 12133.00 2.1134e+04 338.44 15277.00 7.8284e+03 37554.000 41480.00 2021.10 7859.00 15960.0 1.1050e+04 NA 26969.00 1786.30 29879.00 9696.40 25494.000 8517.900 11997.00 12147.00 1.4632e+04 5752.90 14356.00 48664.00 7402.90
DHDVGSELPPEGVLGAL 53829.0 22727.00 223660.00 21632.00 NA 8550.90 143080.00 877.55 98474.00 NA 3.0218e+05 45663.00 37970.00 86872.00 317800.0 7.7995e+04 7095.70 NA 122840.00 290040.00 285520.00 369320.00 124700.00 129400.000 30644.000 105550.000 124710.00 31650.000 59908.00 28208.0 189880.00 66405.00 105950.00 80929.00 4796.600 7374.00 5357.100 127280.00 58674.00 58111.00 61468.00 28845.00 10214.0 10762.000 6082.40 78316.0 37564.00 11772.00 182270.0 7.9519e+04 3.2825e+05 26250.00 5.6864e+04 81883.00 1.4909e+05 48686.00 111550.00 97826.0 67503.00 181770.0 184910.00 13939.000 168060.00 1.1544e+05 33664.00 44419.00 9.1798e+04 32825.000 49907.00 157440.00 140090.00 10080.0 5.1580e+04 548.62 20966.00 NA 16197.00 55175.00 16460.000 176920.000 53502.00 NA 3.3614e+04 54719.00 40461.00 3092.30 80114.00
SQDASDGLQRLHMLQ 566670.0 43182.00 200790.00 29064.00 6.2278e+03 1456.00 49331.00 147.98 NA 20021.00 1.9611e+05 16168.00 57588.00 29064.00 228250.0 4.6028e+04 NA 466.090 96861.00 79309.00 154020.00 125360.00 53288.00 20198.000 21543.000 57347.000 6746.80 4275.600 85303.00 105130.0 55860.00 103890.00 138590.00 36372.00 8508.300 NA 3114.700 55792.00 127950.00 54051.00 157040.00 54010.00 223870.0 2710.400 2756.60 597930.0 NA 28501.00 409060.0 5.0668e+05 1.7699e+05 84180.00 4.6555e+05 123090.00 2.9744e+05 41811.00 64339.00 149470.0 35079.00 33452.0 78571.00 9779.500 10454.00 1.0371e+05 11151.00 18455.00 9.5836e+03 30599.000 354790.00 30332.00 6540.60 129920.0 1.1344e+05 148460.00 156030.00 41758.00 283880.00 4321.20 165590.000 33008.000 25356.00 75706.00 1.8394e+05 4784.40 24896.00 210750.00 100360.00
YRITEATKTVGSDTF 330080.0 11216.00 19985.00 828.55 2.2248e+02 10397.00 19814.00 8397.90 64481.00 NA 1.8945e+05 11986.00 NA NA 220350.0 4.6291e+04 NA NA 38222.00 24640.00 18312.00 27240.00 10911.00 2822.100 NA 9801.100 NA NA 18872.00 64202.0 42358.00 89943.00 48720.00 16343.00 NA NA 3483.400 28283.00 71258.00 87945.00 69415.00 41885.00 53160.0 6383.800 15060.00 611790.0 3627.70 12089.00 235800.0 3.5235e+05 1.1790e+05 108850.00 5.8197e+05 55423.00 1.7674e+05 31562.00 8989.40 120290.0 20051.00 166940.0 25445.00 1722.200 NA 2.7839e+04 NA NA NA NA 116500.00 13437.00 3366.70 115370.0 9.4792e+04 76913.00 93532.00 19754.00 192030.00 19555.00 32939.000 10861.000 5423.30 76181.00 2.0988e+05 32048.00 81520.00 211690.00 86562.00
NKEIPAWVPFDPAAQ 1016900.0 5434.30 52942.00 NA 1.8687e+04 1025.30 16834.00 NA 13160.00 NA 6.2495e+04 40282.00 8269.80 15314.00 64423.0 1.1084e+04 NA NA 26224.00 4372.60 2377.50 2095.00 2450.60 7586.600 1829.200 1754.600 NA NA 3355.60 10635.0 285910.00 1017700.00 116310.00 6174.90 1746.900 NA 2827.600 23690.00 20819.00 62764.00 5258.00 16533.00 570340.0 825.080 652.57 240700.0 NA 9902.10 136600.0 3.5630e+05 2.0009e+04 54694.00 9.9737e+04 93203.00 2.6738e+04 13385.00 15373.00 16070.0 58243.00 52682.0 19103.00 NA 227.57 7.0717e+03 NA 1065.20 1.5835e+03 1520.400 30096.00 2465.70 1027.90 279520.0 7.1818e+04 42058.00 52662.00 27141.00 291980.00 1423.60 8239.900 9487.100 296.61 28044.00 2.4464e+04 NA 25209.00 86898.00 14023.00
VIDQSRVLNLGPITR 296860.0 NA 333260.00 NA NA NA 1533.20 NA 40615.00 110780.00 1.9184e+06 9663.00 NA NA 1052200.0 1.5737e+05 NA NA NA 82902.00 79058.00 134080.00 486210.00 NA NA 8460.200 65492.00 1403.400 26697.00 NA 271490.00 10107.00 39767.00 NA NA NA NA 248190.00 363200.00 91378.00 17991.00 NA NA NA NA 267130.0 NA NA 221100.0 6.1668e+05 1.1509e+05 573310.00 1.2135e+06 494580.00 3.2850e+06 32068.00 33005.00 75545.0 63637.00 1183000.0 NA NA 24497.00 1.8334e+04 773940.00 NA NA NA NA 318290.00 8434.60 597830.0 1.5351e+05 36212.00 8925.00 38959.00 7795.90 17539.00 NA NA NA 109400.00 1.4316e+04 1663.80 142830.00 41188.00 50005.00
DEAGSEADHEGTHSTK NA 60437.00 75398.00 101440.00 NA NA 54470.00 12110.00 23131.00 66172.00 3.0662e+05 37705.00 24711.00 90965.00 188780.0 NA 17236.00 542.730 67232.00 NA NA 7312.90 2563.70 3994.700 6300.000 9344.900 15752.00 1979.400 NA 11876.0 NA 13486.00 NA NA NA NA NA NA 11104.00 NA NA NA NA NA NA NA 139900.00 110280.00 197570.0 NA 6.7266e+04 NA NA NA 4.0432e+04 112950.00 72588.00 155630.0 28664.00 49839.0 17401.00 NA 11630.00 NA NA 2836.20 NA NA NA NA NA NA 1.3246e+04 NA NA NA 4024.20 NA NA NA NA 11355.00 1.3976e+04 NA 3269.60 2671.30 NA
DAPGQYGAYFHDDGF 540180.0 86436.00 328100.00 133510.00 3.7194e+04 16473.00 106670.00 NA 116700.00 37967.00 7.2366e+05 47724.00 76342.00 236790.00 266640.0 4.3706e+05 1230.30 NA 378660.00 508650.00 338690.00 348110.00 152750.00 96985.000 124470.000 57940.000 10535.00 22193.000 134240.00 369850.0 556490.00 779980.00 680850.00 440830.00 9993.900 2683.50 NA 393610.00 255250.00 193310.00 145780.00 93600.00 74117.0 15907.000 18507.00 2008700.0 14245.00 56840.00 667560.0 7.6542e+05 5.7562e+05 43640.00 1.7504e+05 154010.00 3.8844e+05 47429.00 166680.00 298950.0 73492.00 333900.0 309980.00 14647.000 67805.00 1.8816e+05 14228.00 26268.00 2.1374e+05 36161.000 365460.00 247120.00 161680.00 278490.0 5.7665e+04 86687.00 97131.00 7180.60 416010.00 53985.00 115210.000 77425.000 142730.00 112370.00 2.7548e+05 50197.00 91096.00 65429.00 169760.00
SGSVIDQSRVLNLGPI 1164100.0 11031.00 709640.00 5959.40 NA NA 30872.00 NA 85976.00 174320.00 1.8006e+05 23028.00 NA 304590.00 1083700.0 8.3578e+04 NA NA 226190.00 207350.00 663040.00 768610.00 90423.00 11363.000 2286.800 64107.000 185610.00 34075.000 1310.90 12759.0 6901.10 NA 48675.00 NA NA 1415.10 NA 24246.00 NA 17394.00 8341.20 NA NA NA 3629.20 681680.0 50460.00 51345.00 990900.0 5.0663e+05 1.6786e+05 45453.00 7.1179e+02 1787500.00 2.1070e+05 48522.00 NA 315440.0 NA 1110800.0 75428.00 16140.000 412220.00 4.1678e+04 6721.20 13820.00 3.5034e+05 NA 209850.00 78826.00 49353.00 3658.6 1.0922e+04 19466.00 8567.10 NA 37661.00 1371.60 NA 15289.000 1624.60 152970.00 8.4984e+03 4355.10 3040.80 24229.00 60512.00
VKVWPQQPSGELFE 141590.0 NA 216880.00 NA NA NA NA NA NA 3131.40 6.4394e+04 NA NA 3993.10 10433.0 5.3139e+03 NA NA 11765.00 1865.20 4823.30 NA 796.80 165.670 599.310 NA NA NA NA 40678.0 36733.00 456120.00 175030.00 13769.00 NA NA NA 4115.20 3761.80 7943.70 6880.80 3103.20 23296.0 NA NA 361240.0 NA NA 121440.0 8.2419e+04 7.4074e+04 6505.90 NA 2054.40 1.6652e+04 NA NA 21910.0 19635.00 71861.0 6398.70 NA NA 4.2773e+04 NA 536.71 2.5686e+03 NA 21926.00 3342.90 3285.90 32727.0 6.5456e+03 13114.00 3400.90 NA 67797.00 NA 1533.700 57.176 2491.50 14989.00 5.4789e+04 NA 2023.00 14195.00 8140.70
VQVFAPANALPARSEA 58362.0 166020.00 47583.00 157990.00 6.8397e+04 100610.00 189040.00 40642.00 126620.00 100960.00 4.1325e+04 86370.00 90397.00 89564.00 31805.0 1.9460e+04 59611.00 61314.000 110690.00 37275.00 19097.00 13071.00 6479.90 80736.000 62804.000 121590.000 10046.00 39185.000 77195.00 55944.0 110130.00 82020.00 40757.00 26197.00 12900.000 29422.00 25696.000 50102.00 48055.00 28869.00 66176.00 41082.00 78552.0 17150.000 81704.00 130440.0 80091.00 138780.00 56386.0 1.7739e+05 4.8537e+04 9365.60 1.2519e+05 53754.00 5.8527e+04 130130.00 188670.00 203600.0 119100.00 74109.0 100900.00 114920.000 46834.00 2.4632e+04 2265.70 65760.00 3.6829e+04 67173.000 74341.00 15938.00 29708.00 72756.0 3.0666e+04 29785.00 68630.00 10485.00 92838.00 44532.00 70436.000 61782.000 37615.00 36392.00 4.1172e+04 35939.00 45821.00 112950.00 39243.00
VSLGSPSGEVSHPRKT 919970.0 NA 86255.00 NA 2.1676e+04 1517.30 3654.70 2500.20 6731.70 NA 1.6740e+05 NA 18222.00 59171.00 NA 1.0945e+05 NA NA NA 15037.00 231330.00 193450.00 31664.00 14978.000 41296.000 5146.200 894.51 911.650 7058.20 278250.0 132550.00 3862300.00 850610.00 336850.00 2964.200 NA 3938.400 19653.00 47185.00 202260.00 118850.00 14126.00 677410.0 2133.300 NA 1752400.0 NA 53228.00 495500.0 1.3101e+05 5.9495e+05 NA 5.7986e+04 NA 1.1892e+05 NA 109070.00 121210.0 NA NA 50189.00 NA 674.98 2.5469e+05 50868.00 12392.00 2.1373e+04 801.910 147270.00 43564.00 14564.00 477520.0 1.1623e+05 317390.00 74035.00 103200.00 696030.00 8627.80 6980.200 12394.000 38864.00 128720.00 5.7559e+05 2627.40 8397.40 55738.00 101450.00
AKADAAPDEKVLDSGF 118520.0 24041.00 131660.00 11125.00 NA NA NA NA 13525.00 NA NA NA 7460.70 9499.30 31238.0 4.2744e+04 NA NA 46270.00 20835.00 13416.00 1332.60 NA 13779.000 4725.600 27978.000 NA 8.340 18599.00 37827.0 36637.00 87251.00 11705.00 4638.50 4374.500 NA 5796.600 18236.00 2875.10 43238.00 38800.00 37376.00 57592.0 4880.900 NA 199690.0 NA 30411.00 127360.0 2.0980e+05 2.9055e+04 NA 4.4511e+04 1606.00 5.3118e+04 37795.00 16973.00 58427.0 NA 111360.0 NA 2994.600 4794.60 1.3823e+04 NA 6536.50 9.8373e+03 3076.300 82386.00 4450.50 NA 31770.0 2.4570e+04 NA 59984.00 9569.60 141220.00 7187.30 33129.000 28369.000 16453.00 168.94 4.1189e+04 4450.10 30986.00 98779.00 18448.00
VVVHAGEDDLGRGGNQ 26895.0 NA NA 1131.90 NA NA 1384.60 NA NA NA NA NA 2008.60 5044.90 NA NA NA NA 5307.10 4312.40 2283.60 NA NA 3599.300 NA 5506.900 NA NA NA 4963.1 NA NA 3051.80 2672.40 3533.100 3029.20 3126.100 2166.40 NA NA 9277.70 NA 40108.0 NA NA 35289.0 NA 8137.70 NA NA 8.3256e+03 30147.00 NA 18732.00 NA NA NA 12966.0 NA NA 4388.90 2948.600 312.89 8.1758e+02 NA 1452.90 2.6892e+03 1715.200 6100.00 NA NA NA 3.1059e+04 NA 31480.00 NA 18066.00 759.74 20790.000 19451.000 NA 6556.20 NA 5284.90 9463.10 9893.40 1490.10
ANYPDLPSAYQPGIL 39808.0 10102.00 37086.00 11064.00 NA 5019.40 23860.00 1514.70 27374.00 NA 2.8189e+04 15322.00 14811.00 12554.00 4541.3 NA NA 887.010 24792.00 NA 3217.70 6199.60 9368.30 8419.600 2742.100 21267.000 NA 4198.500 10832.00 6417.4 19139.00 7531.70 4809.70 1566.60 324.120 NA 393.800 5893.00 10136.00 NA 8086.40 11219.00 21507.0 1213.300 4691.10 72541.0 1509.90 13720.00 NA 1.7503e+04 1.4803e+04 6836.60 3.8060e+04 4485.40 3.0151e+04 5428.40 19647.00 29099.0 30045.00 19713.0 21854.00 5820.800 9031.00 2.4975e+04 NA 5151.20 3.2663e+03 4232.500 41345.00 2658.30 6393.70 10180.0 NA 3299.70 9961.70 NA 22510.00 1150.20 2458.100 1852.900 2841.40 3035.10 7.1721e+03 NA 3254.70 5302.80 6220.00
VGGGEQPPPAPAPRRE 415220.0 103720.00 111390.00 100680.00 2.4592e+04 49356.00 115360.00 16852.00 92225.00 125360.00 5.3744e+05 NA 38173.00 96933.00 528370.0 3.8792e+05 29211.00 11728.000 177220.00 150680.00 245190.00 368020.00 254080.00 63848.000 28016.000 124410.000 178080.00 58499.000 244270.00 226460.0 330020.00 162470.00 156610.00 116030.00 23863.000 62815.00 23661.000 227330.00 440380.00 402180.00 314190.00 66098.00 575280.0 33839.000 44380.00 565330.0 102490.00 78188.00 457260.0 3.1453e+05 3.4833e+05 261370.00 2.7919e+05 368180.00 3.4024e+05 NA NA 153710.0 NA 484220.0 107170.00 48277.000 124500.00 1.0476e+05 465410.00 109360.00 1.4605e+05 33632.000 135160.00 198870.00 43664.00 556340.0 4.7973e+05 676590.00 129860.00 304870.00 288240.00 135200.00 63233.000 87513.000 130030.00 542470.00 1.8072e+05 118520.00 252410.00 250490.00 275380.00
SVIDQSRVLNLGPIT 119970.0 NA 39126.00 NA NA NA 16973.00 NA 19846.00 44675.00 1.6700e+04 4845.60 5806.30 75883.00 78863.0 2.0425e+04 NA NA 43537.00 104770.00 46558.00 64100.00 4995.10 16987.000 6504.600 8631.500 36932.00 4684.700 NA 1790.6 NA NA 10459.00 NA NA NA NA NA NA NA 2340.00 NA NA NA 843.20 40817.0 24112.00 13959.00 246970.0 2.9715e+04 3.9926e+04 1948.90 NA 163820.00 1.3563e+04 5203.70 14908.00 86294.0 46862.00 27959.0 7322.70 3439.400 13032.00 NA NA 24851.00 4.4654e+04 807.850 26041.00 3621.10 3420.30 NA NA 483.97 1480.20 NA 6676.00 NA NA 596.640 2126.20 5030.80 NA 237.91 NA 404.70 6241.10
IKFPEPGAIKVPEQG 498560.0 67262.00 424740.00 20023.00 NA NA NA NA 1028800.00 10868.00 1.1546e+05 NA NA 54373.00 54408.0 7.2397e+04 NA NA 31759.00 9446.00 2916.20 7921.70 108190.00 6632.900 NA 48196.000 NA 5271.700 4552.80 15869.0 6656.10 142790.00 17724.00 735.71 1321.300 3446.20 NA 46305.00 55530.00 36138.00 44469.00 21198.00 539130.0 NA 38762.00 18690.0 24250.00 3132.00 250140.0 1.1230e+05 6.3962e+04 130090.00 1.4085e+05 21713.00 9.3486e+04 206590.00 194220.00 14295.0 NA 714940.0 9740.70 3852.600 7288.60 2.1981e+04 44658.00 36379.00 3.1077e+04 NA 22137.00 3747.80 3694.00 10041.0 5.4948e+05 79407.00 84626.00 57201.00 177310.00 3035.30 6078.600 28607.000 NA 240070.00 4.3026e+04 71786.00 18054.00 155060.00 48100.00
WQGVEVGEAGQGKDF 32906.0 NA NA 4179.80 NA 231.93 1669.10 NA 1814.30 NA NA 3555.30 NA 3133.60 NA NA NA NA NA 4596.70 NA 3989.30 1225.90 NA 837.120 2912.000 NA NA 10833.00 16990.0 45050.00 81583.00 42597.00 17011.00 NA NA NA 19794.00 1421.20 NA 11936.00 6115.80 37448.0 1435.900 NA 78739.0 NA 1719.70 NA 7.3353e+04 1.7588e+04 NA NA NA 1.9234e+03 NA 20823.00 1102.2 871.98 NA 13396.00 1281.900 NA 2.6355e+03 1621.40 NA NA NA 26534.00 NA 3106.20 NA NA 13316.00 NA NA 34375.00 NA 11540.000 NA 6974.40 NA 1.0364e+03 1934.90 NA 7333.20 11476.00
IDQSRVLNLGPITR 366320.0 6679.00 106780.00 NA 1.3365e+03 NA 25948.00 NA 28213.00 92803.00 2.8026e+05 NA 10665.00 27997.00 1087600.0 4.4216e+05 NA NA 11297.00 29477.00 66588.00 82079.00 91254.00 NA NA NA 41150.00 460.630 4277.60 15757.0 24020.00 77955.00 52926.00 1339.00 NA NA NA 65634.00 36118.00 37100.00 44089.00 1106.30 NA NA 3768.60 445050.0 8553.00 3955.30 595000.0 2.1191e+05 2.9593e+05 146360.00 5.4226e+05 478080.00 7.1289e+05 50668.00 161330.00 126690.0 282870.00 1913800.0 NA NA 2400.60 NA 121840.00 1216.30 4.3430e+03 NA 3170.60 61876.00 995.68 18304.0 7.4817e+04 78206.00 31674.00 26242.00 16803.00 5799.10 NA NA 3933.80 49214.00 NA 6876.30 27037.00 24828.00 48692.00
YLAPNNLKPVVAEF 569930.0 11560.00 1404100.00 4427.50 6.8574e+02 NA 2343.60 NA NA NA 1.1671e+05 NA 2966.80 NA 329450.0 2.2636e+04 NA NA 341360.00 5118.60 59973.00 3695.60 NA NA 307.070 8360.300 NA NA 1375.60 2290.0 16408.00 12830.00 22229.00 NA NA 197.82 NA NA 2932.40 7586.90 6564.00 2272.50 40240.0 1515.600 NA 206510.0 NA 904.41 394470.0 9.2170e+04 5.2106e+04 NA NA NA 1.2098e+05 6324.20 137830.00 253280.0 NA 156640.0 11475.00 NA NA 9.8953e+05 NA NA 8.4783e+03 333.530 67646.00 2272.80 935.51 3608.8 1.8180e+03 5481.60 7605.60 NA 25189.00 1869.60 4917.400 4208.600 NA 3989.80 4.0798e+04 NA 7882.40 18511.00 1860.90
LRLPEKVPSAPPQE 99270.0 NA 34492.00 7568.00 NA NA 25526.00 NA 31335.00 22239.00 NA 16899.00 NA 11216.00 NA 7.2580e+04 NA NA 9272.60 8192.80 14534.00 16802.00 8068.10 3328.900 NA 9586.400 NA NA 14753.00 27393.0 15293.00 43546.00 NA 16649.00 NA NA NA 37402.00 27487.00 NA 35278.00 19508.00 200460.0 NA NA 200100.0 NA 13447.00 102620.0 1.3420e+05 3.7161e+04 13324.00 8.2738e+04 92112.00 2.9196e+04 32485.00 NA NA 28298.00 101080.0 8075.00 3056.000 8263.20 NA NA 3404.10 8.2250e+03 NA 26926.00 16368.00 NA 112130.0 5.7279e+04 148650.00 49293.00 102070.00 182060.00 7503.10 NA 6188.000 NA NA NA 11195.00 NA NA 49583.00
HSARPGAPPPQPLDL 358670.0 25382.00 NA NA 5.9386e+02 NA NA NA 14891.00 NA NA NA 7340.90 2797.50 NA 6.9423e+04 NA NA NA NA 2244.30 NA NA NA 11311.000 NA NA NA 23062.00 23467.0 23431.00 69052.00 5111.60 8210.30 1606.100 NA NA 28350.00 7461.10 175530.00 7370.30 NA 449280.0 61.727 NA 662670.0 NA 25328.00 NA 4.2918e+05 NA 3738.60 9.5840e+04 45048.00 3.6215e+04 1569.80 7999.60 19172.0 NA 58432.0 NA NA NA 2.8514e+04 NA NA NA NA 71488.00 3235.30 NA 141030.0 1.7025e+03 156970.00 127810.00 NA 422790.00 NA 27431.000 NA 925.51 6850.30 8.6520e+04 NA NA 56109.00 51251.00
VAWKADSSPVKAGVE 511810.0 117770.00 NA 114950.00 5.2970e+04 56258.00 303130.00 1114.20 177170.00 NA 3.1180e+05 101710.00 44753.00 113470.00 12856.0 7.4611e+04 NA NA 127110.00 65863.00 21586.00 18848.00 14203.00 49938.000 128570.000 46711.000 NA 6930.900 57850.00 106970.0 628660.00 1100800.00 267700.00 158460.00 55276.000 14686.00 29830.000 125910.00 73917.00 66162.00 69338.00 222940.00 1877800.0 21051.000 7934.90 474430.0 NA 124960.00 156590.0 1.2614e+06 8.0781e+04 79459.00 1.8184e+05 922.46 7.9853e+04 42900.00 68121.00 149220.0 140630.00 218920.0 65561.00 21034.000 19362.00 3.1920e+04 4363.10 27429.00 8.4398e+04 16230.000 232660.00 11696.00 17582.00 295220.0 2.3122e+05 80240.00 357220.00 41291.00 536190.00 29981.00 119550.000 141010.000 33268.00 35947.00 1.8640e+05 23737.00 88477.00 207110.00 55353.00
YRITEATKTVGSDT 45523.0 NA NA NA NA NA NA NA NA NA 1.8362e+04 NA NA NA 8441.8 5.8468e+03 NA NA 16169.00 8289.00 8460.70 9534.50 1953.90 809.500 NA 7647.800 NA NA 12968.00 38804.0 42228.00 44811.00 36641.00 NA NA NA NA 13226.00 16018.00 22431.00 24985.00 17560.00 45505.0 1090.800 NA NA NA 5035.00 NA 4.9382e+04 1.8985e+04 9850.00 NA NA 5.7649e+03 4070.70 NA 15559.0 8150.70 16737.0 25031.00 568.900 NA 3.1786e+04 NA NA NA NA 47930.00 NA 671.78 29442.0 3.3535e+04 14338.00 70260.00 2000.00 49403.00 1779.80 23523.000 3628.000 5664.00 24653.00 8.0163e+04 1594.10 25172.00 115210.00 17898.00
TWLNPDPSQKQNL 105000.0 26233.00 61415.00 53317.00 3.1872e+04 22880.00 119890.00 13086.00 NA 54046.00 2.8477e+04 15280.00 38961.00 14901.00 NA 9.9860e+03 1772.30 11657.000 26022.00 5425.90 7571.60 11093.00 3864.30 13634.000 12328.000 4856.400 1407.00 2468.800 28111.00 22128.0 46456.00 24405.00 9892.30 9229.90 7878.400 6429.40 14558.000 35029.00 32010.00 18485.00 46614.00 20503.00 29206.0 3367.700 28682.00 130310.0 4796.20 133720.00 NA 1.5814e+05 2.9445e+04 14594.00 NA 48376.00 NA 61699.00 36059.00 36454.0 NA 38768.0 17778.00 31305.000 6123.50 NA NA 6556.80 NA 8272.500 21267.00 1214.30 3156.50 14855.0 1.3564e+04 22215.00 73126.00 5109.00 79542.00 15636.00 76645.000 18416.000 11923.00 12963.00 3.0018e+04 NA 32791.00 163020.00 NA
SIDWTKIEPSVNF 33922.0 NA 18425.00 NA NA NA NA NA NA 1049.10 1.3630e+04 NA NA NA NA 4.8314e+03 NA NA 19690.00 1369.40 1725.00 2561.20 1145.50 2255.100 1665.900 1439.700 NA NA 1360.80 5063.8 13095.00 23446.00 7221.60 NA NA NA NA 9360.90 4299.30 7812.70 NA 3287.00 52642.0 NA NA 34820.0 NA NA 14581.0 3.7130e+04 5.5845e+03 6731.80 NA 6173.70 7.3291e+03 NA NA 9329.6 NA 20305.0 7366.20 314.480 552.34 5.4265e+03 NA NA 2.0442e+03 842.270 15230.00 NA 2502.20 25823.0 5.9745e+03 6530.70 6102.50 NA 28112.00 287.35 762.230 NA NA 7923.30 9.7940e+03 NA 2103.80 6989.60 4342.50
IEVDGRVYHVGLGD 12138.0 12204.00 NA NA NA NA 1705.50 NA 8368.00 NA NA NA 19152.00 6338.80 8477.6 2.9656e+02 NA 1431.900 NA NA NA NA NA NA 7972.700 5850.200 NA 1129.300 8129.80 2982.0 12656.00 14004.00 1617.00 4111.10 5863.200 3887.10 13218.000 NA 7485.80 NA NA 19617.00 316150.0 NA NA 12122.0 NA 23943.00 NA 2.9711e+04 NA NA 1.3685e+05 2288.10 NA NA NA NA 136730.00 NA 1768.20 4841.500 2086.90 NA NA 2612.20 NA 4822.700 9460.10 NA NA 13167.0 NA 1078.00 22374.00 NA 13461.00 6063.40 42515.000 9157.300 8159.20 NA NA 6016.90 8237.70 32544.00 NA
YQAEWDDYVPKL 28236.0 NA 26930.00 NA NA NA 124.02 NA 23120.00 NA 4.4623e+04 19767.00 NA NA 51226.0 1.1489e+04 NA NA 3579.80 15209.00 3027.30 13948.00 16393.00 NA NA 787.180 NA NA NA 6425.2 4716.30 11549.00 9715.00 NA NA NA NA 8311.40 11050.00 41823.00 6679.30 NA NA NA NA 23376.0 NA NA 50620.0 1.2245e+04 1.2701e+04 13268.00 1.1060e+05 98641.00 6.0239e+04 NA NA NA 80586.00 21313.0 3968.70 NA 943.10 NA NA NA 1.5733e+03 NA 2833.80 3345.70 869.31 10555.0 9.0224e+03 7360.20 NA NA 8008.00 NA NA 878.830 NA 9769.10 NA NA NA 2171.20 8713.60
VIDQSRVLNLGPIT NA 148.39 62204.00 7371.00 NA NA 5764.40 NA 19282.00 21521.00 2.4913e+04 NA NA 13241.00 36183.0 NA NA NA 25097.00 41764.00 15956.00 19283.00 3198.20 1565.700 881.190 19779.000 19079.00 4559.200 NA NA 1122.60 NA 3493.20 NA NA NA NA 580.32 NA NA 154.04 NA NA NA NA 6344.7 11232.00 6410.20 22775.0 2.7896e+04 4.2145e+03 NA NA NA 1.5969e+04 2315.30 4120.30 35617.0 7603.00 56568.0 5254.20 3294.200 33866.00 2.6905e+03 2152.60 3361.80 6.8273e+03 NA 5171.30 4339.90 6771.80 838.7 NA NA NA NA NA NA NA 248.480 NA 3107.10 NA NA NA NA 2202.50
ISQDNALRDEMRA 20857.0 12109.00 NA 25239.00 1.1677e+04 16115.00 28291.00 NA 36428.00 NA 4.3649e+04 15894.00 11169.00 22668.00 NA NA NA NA 2629.70 4006.50 2776.50 2118.10 NA 20266.000 13701.000 11514.000 NA 2883.000 15397.00 18107.0 105440.00 109800.00 35679.00 24943.00 6687.800 NA 4994.100 30246.00 18111.00 23390.00 6536.20 26786.00 60997.0 1396.300 2834.60 42925.0 NA 15423.00 6197.3 1.9133e+05 6.7330e+03 NA NA NA NA 18247.00 NA 16674.0 NA 32180.0 19089.00 8097.700 5775.70 NA NA 3828.50 1.0988e+04 7623.600 39233.00 7068.00 6169.80 45796.0 2.4603e+04 NA 30638.00 NA 27888.00 5473.60 31379.000 19368.000 13406.00 4064.80 1.7087e+04 6399.90 NA 18973.00 13160.00
FDSDPITVTVPVEV 12468.0 10761.00 NA 3793.90 NA NA NA NA NA 56525.00 1.6755e+04 NA NA 10383.00 NA NA NA NA 12309.00 6745.00 NA NA NA NA 5064.200 17792.000 NA NA 47087.00 23247.0 69274.00 38535.00 17602.00 12172.00 NA 2025.00 NA 19271.00 58948.00 28946.00 32843.00 12201.00 23792.0 NA NA 15546.0 2746.80 10210.00 NA 1.9854e+04 4.9968e+03 NA 2.1585e+04 NA 2.0935e+04 NA 23388.00 19582.0 NA 5408.8 12223.00 2570.600 4415.00 4.9034e+04 NA 2213.80 1.0871e+04 3566.200 12099.00 NA 9640.80 20258.0 NA 5908.40 28834.00 NA 39688.00 20301.00 16513.000 6855.800 6446.50 5613.80 2.4055e+04 6449.60 28529.00 47591.00 7836.90
VAWKADGSPVKAGVE 95365.0 20594.00 70220.00 12879.00 1.2072e+04 7859.90 21448.00 NA NA 7211.30 4.6695e+04 NA NA 10619.00 NA NA NA NA 14636.00 7156.00 NA NA 1626.00 8115.900 15439.000 12378.000 NA 937.370 7399.50 13920.0 91746.00 181330.00 35191.00 35658.00 10374.000 3709.50 3457.600 22397.00 8424.80 18204.00 8621.20 35685.00 395160.0 NA NA 40992.0 NA 19077.00 NA 1.8300e+05 NA NA NA NA NA 10547.00 NA 30316.0 16835.00 48748.0 10826.00 4323.600 6381.20 1.1871e+04 NA 3443.20 1.2924e+04 3668.000 29498.00 3677.50 3252.00 30981.0 4.9363e+04 13026.00 91443.00 NA 76870.00 4979.10 37953.000 21618.000 4246.20 4916.40 7.3611e+04 5142.20 20467.00 63188.00 5758.40
PRGHSGEPGLPGPPGP 89397.0 34882.00 82940.00 35346.00 2.0647e+04 65621.00 29288.00 11449.00 45223.00 23737.00 NA NA 8764.90 14893.00 19224.0 NA 4584.40 34997.000 71389.00 32629.00 72585.00 99830.00 87900.00 40415.000 32184.000 113680.000 202000.00 74124.000 174700.00 159990.0 98713.00 41562.00 35725.00 54346.00 11890.000 35090.00 8156.500 48271.00 180160.00 141430.00 89472.00 44650.00 192900.0 31151.000 42523.00 48671.0 32422.00 24372.00 NA 4.3485e+04 2.1748e+04 NA NA 107480.00 1.2772e+05 124000.00 78300.00 77066.0 41237.00 63794.0 84181.00 69781.000 178080.00 4.6761e+04 50191.00 87038.00 4.6718e+04 42283.000 85312.00 77512.00 50089.00 80680.0 1.1356e+05 239160.00 84867.00 46288.00 100150.00 47096.00 38060.000 54140.000 59424.00 133600.00 1.1108e+05 110330.00 79205.00 65999.00 140050.00
G(+42.01)DKPIWEQIGSSF 53306.0 NA 44103.00 3035.60 NA NA 13024.00 NA 14079.00 NA 5.4627e+04 1354.00 NA 11764.00 27629.0 NA NA NA 52377.00 34750.00 11776.00 18500.00 10334.00 16480.000 5750.000 7802.200 2873.70 NA NA 12164.0 10910.00 20137.00 9384.80 NA NA NA NA NA 18037.00 9223.90 8561.90 9030.90 41213.0 NA NA 32787.0 NA NA 43297.0 4.5691e+04 2.9360e+04 29492.00 3.9409e+04 24136.00 5.1599e+04 8201.50 10062.00 23514.0 6625.60 23694.0 7936.50 NA 2706.60 3.7944e+04 3477.60 NA 9.8805e+03 3854.600 37729.00 9443.50 4259.00 8760.9 4.2487e+03 9130.10 10942.00 NA 21509.00 NA 7791.800 NA NA NA 1.2526e+04 NA 8183.40 8273.90 8630.90
VHLTPEEKSAVTAL 38524.0 13338.00 964470.00 78563.00 NA NA NA NA 24468.00 NA 1.9925e+05 NA NA NA 800490.0 7.2670e+04 NA 168.800 NA 103790.00 37002.00 NA 8818.50 NA NA 7603.600 NA 26170.000 66953.00 125810.0 16388.00 9738.20 NA NA 4631.100 547.66 3591.500 18551.00 257690.00 7300.70 11845.00 136320.00 9090.9 NA NA NA NA 60913.00 2270400.0 2.2970e+04 NA 2115.60 8.7320e+04 180170.00 1.3349e+05 9966.80 NA 79023.0 NA NA 84771.00 NA NA 2.8553e+07 45243.00 21286.00 5.3808e+04 3492.800 13125.00 2112.00 32159.00 162750.0 2.6066e+05 NA 26014.00 NA 285670.00 2590.20 14377.000 68452.000 8116.10 NA 3.3382e+07 112920.00 63911.00 267210.00 91704.00
WGSPAASDDGRRTL 55003.0 23703.00 NA 5151.60 NA NA 8685.20 NA NA NA 1.8642e+04 NA NA NA NA NA NA NA 10124.00 5651.20 NA NA NA NA NA 8102.400 NA NA 17167.00 11474.0 11828.00 38470.00 NA 6457.80 NA NA NA 10340.00 32569.00 37246.00 18153.00 52263.00 244440.0 NA NA 168820.0 NA 24601.00 35384.0 1.1606e+05 NA 27478.00 4.2075e+04 NA NA 3759.00 NA 16585.0 NA 48111.0 2329.00 NA NA NA NA NA 1.4163e+04 2231.700 67300.00 NA NA 38503.0 5.3967e+03 49444.00 100280.00 15361.00 251230.00 NA 46324.000 2733.400 NA NA 2.5323e+04 NA 26353.00 25908.00 10127.00
FRVVAQGVGIPEDS 113590.0 51538.00 172900.00 45139.00 4.2772e+04 6984.10 24803.00 NA 67022.00 16881.00 3.4618e+05 32132.00 49703.00 56611.00 3598.7 NA NA 1115.700 212380.00 8742.20 3166.00 4557.60 1782.90 11358.000 55087.000 19015.000 NA 962.550 23395.00 78422.0 203960.00 177400.00 121920.00 21979.00 11648.000 945.83 21920.000 50896.00 63165.00 63004.00 12381.00 58059.00 338180.0 10798.000 5086.10 201790.0 NA 81721.00 281130.0 5.5253e+05 2.2362e+04 NA 1.6431e+05 105060.00 7.6201e+04 62542.00 31904.00 212500.0 NA 110170.0 45361.00 14754.000 3247.90 3.9310e+04 NA 3910.50 3.5209e+03 24001.000 127910.00 2423.40 29118.00 219130.0 4.3943e+04 50176.00 93537.00 50155.00 175460.00 12618.00 134190.000 6126.700 12725.00 33151.00 1.1760e+05 7568.90 53949.00 148780.00 24943.00
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FSSPHGKDLL 983200.0 50146.00 1101600.00 11966.00 1.8252e+04 NA 4426.80 NA NA NA 1.6571e+05 NA 4112.10 NA 617580.0 6.4310e+04 NA NA 452570.00 16178.00 184510.00 11839.00 1533.60 421.760 2276.200 20610.000 NA NA 22957.00 58653.0 218560.00 262200.00 182350.00 2901.60 15022.000 7076.80 NA NA 132470.00 162680.00 171710.00 15305.00 766170.0 9860.100 NA 298510.0 NA 9267.10 781180.0 2.2754e+05 1.0070e+05 35436.00 1.2713e+05 34476.00 1.4947e+05 7325.50 173610.00 195890.0 NA 317770.0 18188.00 NA NA 7.9499e+05 NA NA 1.4867e+04 NA 109140.00 4322.70 226.48 117890.0 8.6617e+04 179460.00 123720.00 7629.80 302600.00 3091.60 76688.000 47085.000 2827.50 67883.00 4.6791e+05 3270.90 167850.00 233850.00 67220.00
PILRHGIQY 586950.0 10085.00 NA 6384.10 NA 1943.80 11059.00 NA 13738.00 1920.40 2.0340e+04 16405.00 9290.20 NA 2921.5 1.1086e+05 NA NA NA NA NA NA NA NA NA 1861.600 NA NA NA NA 5909.60 34519.00 NA NA NA NA NA 16450.00 2059.40 11458.00 4454.80 5067.40 293360.0 NA 736.81 796070.0 NA 35572.00 71068.0 3.7477e+05 3.4075e+04 116690.00 6.6081e+04 147700.00 5.4605e+04 10898.00 12692.00 22128.0 2837.40 102630.0 NA 1193.500 NA NA NA NA NA NA 1975.20 NA NA 28314.0 4.6209e+04 207710.00 35257.00 42989.00 110790.00 NA 9187.000 NA NA 5177.20 1.8890e+04 1845.00 NA 39061.00 3606.10
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GRLASPGFPGE NA 13577.00 223500.00 13890.00 2.1241e+04 NA NA NA NA 12316.00 NA 5088.20 12120.00 5151.80 16755.0 1.6148e+04 NA NA 7718.20 NA 3285.30 NA NA 5855.000 14461.000 1889.900 NA NA 4263.40 15311.0 12324.00 77141.00 15260.00 6188.90 14183.000 NA 23187.000 4136.00 NA 44058.00 NA 12743.00 66584.0 8175.000 6087.80 92306.0 NA 15403.00 147280.0 1.8625e+05 NA NA NA NA NA NA 20049.00 32877.0 NA 143670.0 NA NA NA NA NA NA 8.0867e+03 6498.500 33013.00 NA 1720.60 7556.6 7.5918e+03 18086.00 197520.00 NA 57975.00 2430.20 25390.000 NA 3565.60 NA 7.2117e+04 NA 7463.30 24712.00 7192.90
GPKWPEPVF 96243.0 10283.00 NA 14842.00 4.1879e+02 NA NA NA 49009.00 NA 2.0975e+05 NA 9016.00 11570.00 NA NA NA NA 24233.00 28557.00 42514.00 35471.00 19647.00 4323.800 NA 15377.000 NA 2050.600 20178.00 47131.0 112630.00 51395.00 53082.00 NA 980.260 NA NA 73006.00 76902.00 114250.00 NA NA 20609.0 NA NA 93178.0 NA 33522.00 37033.0 3.5229e+05 NA 82281.00 NA NA 2.4691e+02 NA NA 50797.0 NA 433640.0 NA NA 8157.10 1.6242e+04 15211.00 6134.40 7.3800e+03 NA 22376.00 49033.00 15780.00 138760.0 2.5022e+04 28277.00 16584.00 8715.30 NA 13086.00 NA 9818.800 NA 5171.20 5.5770e+04 NA 46157.00 17849.00 14371.00
IVDKVKPQL 37629.0 73707.00 55024.00 26612.00 2.8359e+04 15217.00 18247.00 8910.70 204960.00 NA 3.8900e+03 5990.70 24457.00 17238.00 NA 4.0440e+02 NA 2708.900 24272.00 NA NA NA 2234.00 14716.000 25483.000 18070.000 NA 1712.500 71248.00 27056.0 38647.00 75975.00 18655.00 13770.00 42263.000 28588.00 1606.500 5065.80 31143.00 4162.30 NA 35039.00 392910.0 2301.400 23910.00 43678.0 788.21 37943.00 11809.0 1.4981e+05 NA NA 2.9934e+04 NA 7.7845e+03 51572.00 48387.00 22395.0 6049.40 106630.0 10373.00 36956.000 3528.30 4.7061e+03 NA 24461.00 4.6295e+03 9714.000 28722.00 NA 608.69 49508.0 2.8501e+04 NA 230310.00 3124.60 104520.00 2268.90 61708.000 33646.000 3057.60 29478.00 4.2479e+04 22497.00 6729.20 83612.00 11013.00
VVLPKHILD 33543.0 2483.60 NA NA NA NA 5707.50 NA NA NA 1.1246e+05 668.30 NA 3456.50 35329.0 1.9818e+04 NA NA 1957.00 19211.00 4382.50 6569.90 14635.00 NA NA 5383.000 760.37 NA 7345.00 6899.4 8296.00 9787.30 7948.00 NA NA NA NA 7990.10 34865.00 10769.00 5436.30 NA 10591.0 NA NA 85372.0 NA 11415.00 14757.0 4.0769e+04 4.2017e+04 NA 4.6683e+04 10705.00 6.5937e+04 NA NA 13372.0 NA 35838.0 3700.90 NA NA NA 13106.00 NA NA NA 6712.60 3510.90 1363.40 30198.0 6.9234e+03 4358.10 5356.50 NA 18448.00 NA 2558.100 NA 1321.40 1122.50 NA 563.51 3993.80 12375.00 6424.80
NVAKGIRSF 171400.0 9831.60 NA 11536.00 7.2637e+03 4512.50 10938.00 NA NA NA 1.4562e+05 NA NA 17559.00 NA NA NA NA 19033.00 10380.00 9835.20 17980.00 11438.00 NA NA 5614.700 NA NA 34964.00 11817.0 64247.00 31701.00 24082.00 4840.90 NA NA NA 41691.00 83484.00 49390.00 27335.00 2838.60 52920.0 NA 3478.70 184870.0 10004.00 23551.00 138630.0 2.0038e+05 1.1850e+05 54678.00 1.5610e+05 56755.00 NA NA NA NA NA NA NA NA NA NA 47995.00 NA NA NA 6355.90 10055.00 NA 91632.0 7.6937e+04 55054.00 10051.00 47335.00 53834.00 7501.20 NA 5256.200 NA 17263.00 3.9992e+04 1899.90 34093.00 36801.00 28826.00
VLNLGPITR 42214.0 89641.00 73835.00 37153.00 1.2291e+04 21050.00 67916.00 7802.90 57980.00 41272.00 9.1648e+04 50865.00 26890.00 27267.00 101160.0 4.2564e+04 17830.00 22648.000 65871.00 56749.00 77191.00 74347.00 16758.00 5364.400 17379.000 60435.000 119170.00 40442.000 43745.00 49726.0 71002.00 23830.00 27312.00 9613.10 4738.600 10659.00 13959.000 75548.00 62110.00 51226.00 61864.00 19678.00 13091.0 8446.400 36943.00 69343.0 45033.00 78777.00 24892.0 1.2389e+05 8.5342e+04 16277.00 1.0886e+05 12510.00 8.1371e+04 84099.00 80174.00 102330.0 NA 186470.0 65538.00 33189.000 84814.00 7.5415e+04 36425.00 27829.00 5.3026e+04 26859.000 54282.00 56024.00 65718.00 48396.0 1.1266e+05 25993.00 13932.00 5852.50 53577.00 42509.00 33336.000 48110.000 47204.00 63440.00 6.0213e+04 11098.00 59576.00 134200.00 22994.00
PGKDGPRGPT 171570.0 68356.00 308090.00 89807.00 2.5088e+04 100970.00 124900.00 27821.00 122590.00 113770.00 2.0927e+05 69586.00 35207.00 56216.00 190550.0 2.6260e+05 14398.00 9548.000 143100.00 155180.00 92814.00 64541.00 103370.00 32033.000 25144.000 82032.000 165510.00 37626.000 125000.00 173210.0 114790.00 137630.00 76909.00 102800.00 18843.000 35113.00 NA 93279.00 188060.00 127370.00 141260.00 71614.00 234670.0 43592.000 57767.00 379970.0 286400.00 46152.00 308210.0 2.7743e+05 1.9926e+05 51193.00 3.5858e+05 NA 2.3930e+05 85712.00 125240.00 110810.0 87091.00 333360.0 39783.00 53744.000 79224.00 5.2960e+04 94510.00 53757.00 7.2013e+04 22456.000 119240.00 111830.00 47036.00 118510.0 1.6942e+05 91396.00 79223.00 27728.00 152570.00 81837.00 67193.000 85507.000 86166.00 198960.00 1.7110e+05 57659.00 101370.00 88807.00 204600.00
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SKWSGPLSL 39945.0 NA NA NA NA NA 2120.20 NA 2554.30 NA 8.3172e+03 NA NA NA 19378.0 9.6344e+03 NA NA 3885.30 2883.50 NA 4220.20 3420.40 NA NA 3246.000 NA NA 1269.50 6075.1 NA 4902.90 1457.40 NA NA NA NA 1720.40 12383.00 6983.60 5266.90 NA 12286.0 NA NA 36177.0 NA NA 12843.0 1.9406e+04 1.3961e+04 5676.50 NA 17100.00 1.2926e+04 NA 1975.80 14654.0 NA 5014.0 3518.60 NA 426.12 5.3799e+03 NA NA 4.2864e+03 NA 5254.00 NA NA NA 3.9786e+03 18141.00 3046.30 NA 16557.00 NA NA 155.630 NA 3626.90 4.0938e+03 NA 1065.40 6216.10 2892.80
YKWKETL 187530.0 22954.00 59591.00 13314.00 NA NA 29798.00 NA 54602.00 37621.00 2.0597e+05 NA NA 6278.10 59628.0 3.0891e+04 NA NA 4326.10 NA NA 964.86 NA NA NA NA NA NA NA 8985.3 15212.00 88889.00 16031.00 NA NA NA NA 20127.00 53185.00 78422.00 NA NA 430790.0 NA NA 427440.0 NA 18361.00 160250.0 4.1574e+05 4.4826e+04 96544.00 1.7409e+05 141830.00 6.4709e+04 NA NA 36487.0 NA 283610.0 NA NA NA 3.5747e+03 NA NA NA NA 19749.00 NA NA 92890.0 1.7548e+04 76883.00 17939.00 112310.00 106360.00 NA NA NA NA NA 5.5126e+04 NA 29663.00 24261.00 17916.00
PRYPVGKF 2025500.0 205260.00 109540.00 118450.00 1.2934e+05 74124.00 167830.00 11520.00 158050.00 NA 5.5080e+05 142460.00 145730.00 59039.00 629680.0 3.6658e+05 NA 3695.300 21951.00 8348.30 4129.50 11065.00 10822.00 2017.400 NA 2834.300 NA 1580.000 86483.00 62513.0 59349.00 107810.00 56268.00 3952.00 33676.000 10296.00 39832.000 39487.00 46541.00 57120.00 30989.00 5321.10 197860.0 10118.000 38258.00 2379000.0 NA 327480.00 597580.0 2.1910e+06 6.8124e+05 763910.00 1.5164e+06 636830.00 7.1436e+05 50671.00 148420.00 274890.0 49608.00 750240.0 4642.40 13403.000 2181.90 9.4972e+03 28036.00 1537.90 NA 1794.200 2983.80 2147.50 1655.90 155740.0 4.5943e+04 127280.00 95749.00 43911.00 97598.00 14782.00 64987.000 4981.700 32117.00 73519.00 1.2278e+05 13617.00 61119.00 268000.00 24163.00
RPPGFSPF 102760.0 NA NA NA 5.0738e+03 13140.00 28437.00 318.09 NA 24282.00 NA 26215.00 12741.00 40250.00 67791.0 3.0907e+04 NA 1245.000 27840.00 13660.00 59102.00 17766.00 NA 4400.100 NA 8988.400 21470.00 NA NA 32753.0 NA 15380.00 53456.00 5190.10 NA NA NA NA NA NA 12835.00 NA 14317.0 NA 12928.00 107230.0 27231.00 NA 37546.0 2.1769e+04 1.3403e+05 NA NA 67852.00 NA 20779.00 22162.00 64001.0 16266.00 71988.0 35535.00 4888.900 NA 7.2203e+02 NA 13641.00 6.4836e+04 NA 40782.00 1075.30 NA NA NA 32232.00 8256.70 6746.40 35344.00 NA NA NA 14563.00 5219.50 3.6765e+04 NA NA 21864.00 NA
LNLGPITR 292700.0 174790.00 103180.00 42045.00 8.2122e+04 59049.00 36792.00 29688.00 38123.00 18366.00 1.0084e+05 35527.00 83350.00 22203.00 107180.0 6.0609e+04 5870.60 49414.000 57786.00 34960.00 23854.00 52952.00 26534.00 7936.400 23378.000 32789.000 14573.00 5111.100 117770.00 288630.0 112010.00 259070.00 115990.00 24412.00 50086.000 28175.00 148250.000 79263.00 195240.00 68980.00 148440.00 127800.00 345910.0 50258.000 84950.00 452620.0 NA 417010.00 137340.0 4.5739e+05 8.4163e+04 30972.00 1.8824e+05 83592.00 1.4721e+05 29009.00 58511.00 89956.0 27281.00 208230.0 48531.00 56739.000 15950.00 6.3969e+04 32126.00 11970.00 8.0407e+03 17583.000 150030.00 11211.00 13667.00 310740.0 1.3847e+05 277540.00 87283.00 11868.00 924680.00 30089.00 292960.000 26527.000 155290.00 134340.00 1.8241e+05 22801.00 102620.00 710940.00 92669.00
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MGPPGNPGP 349680.0 135780.00 NA 193170.00 NA 128170.00 98697.00 26438.00 106630.00 1317.90 5.2382e+05 NA 54946.00 125170.00 NA NA NA NA 381820.00 4172.30 NA NA NA NA 8596.700 NA NA 10047.000 NA 471440.0 NA 214700.00 NA NA NA 49323.00 10734.000 10681.00 NA 823150.00 418510.00 NA 110360.0 NA 48398.00 185080.0 98548.00 58235.00 NA 6.0186e+05 3.6772e+05 133320.00 NA 459940.00 NA NA NA 199730.0 NA NA NA 70918.000 NA NA 86699.00 NA 1.7326e+04 4186.000 NA NA NA NA 4.6613e+05 1142400.00 184050.00 309410.00 568270.00 NA 89484.000 NA 233050.00 NA NA 189890.00 NA 14884.00 938380.00
HASLDKF NA 13763.00 263890.00 NA 2.6878e+03 NA 1129.60 13026.00 7882.90 2465.70 1.1990e+04 4407.00 416.07 4165.00 NA NA NA NA 30830.00 13879.00 17821.00 20778.00 27177.00 NA 10355.000 17103.000 17438.00 8528.900 37301.00 47058.0 36202.00 22880.00 31716.00 16742.00 19495.000 NA 7677.700 18302.00 46476.00 1055.00 155070.00 44211.00 53569.0 NA 4341.50 NA NA 866.72 80687.0 9.1523e+03 1.6092e+04 NA NA 10424.00 1.9510e+04 NA 41419.00 22491.0 19691.00 28253.0 25030.00 25876.000 13560.00 2.2253e+05 26923.00 22932.00 3.2704e+04 7733.200 21134.00 12822.00 16150.00 23064.0 2.7156e+04 15503.00 21018.00 NA 41019.00 NA 22387.000 22990.000 42585.00 29964.00 3.2249e+04 16296.00 30318.00 65837.00 39473.00
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PPPPPPPP 6687.4 29613.00 NA NA 9.2458e+03 3695.40 13118.00 4644.10 13270.00 1840.50 NA 3747.10 NA NA 3444.4 NA 1667.20 9735.000 25887.00 11546.00 29814.00 38130.00 20494.00 20951.000 10554.000 30626.000 32383.00 18875.000 46865.00 34975.0 57290.00 NA 17975.00 14494.00 13308.000 16665.00 9977.800 35241.00 37723.00 26309.00 31648.00 18397.00 69938.0 NA 6572.60 10478.0 NA 2905.90 258310.0 2.4710e+04 NA 8838.00 NA 13147.00 NA NA 19414.00 18036.0 3137.00 NA 34240.00 16004.000 26700.00 NA 19972.00 35933.00 3.7900e+04 9977.200 21167.00 22321.00 12270.00 40922.0 1.1475e+03 54124.00 46901.00 NA 55439.00 17165.00 17969.000 32846.000 33924.00 30076.00 NA 23099.00 48890.00 60351.00 43684.00
KLGHPDT 9143.2 37988.00 1266200.00 13202.00 4.2437e+03 7429.10 7973.10 NA 153940.00 NA NA NA NA NA NA NA 5742.20 211.410 5398.10 6051.00 7583.70 1460.00 3402.00 1242.200 3124.400 2478.600 4149.20 3509.400 10040.00 10983.0 4898.10 7940.40 7898.10 6860.80 2976.900 6866.00 NA 2375.90 NA NA 6642.60 4458.90 3679.2 2575.800 4224.90 NA NA 7652.40 18247.0 2.6237e+04 NA 1234.30 NA NA NA NA NA NA 961.58 NA 2547.20 6973.100 1773.20 NA 3561.60 2856.50 9.8437e+03 3013.800 2400.60 1743.70 2832.10 3773.0 7.4680e+03 NA 6399.70 NA 8669.60 5241.20 6670.400 7743.100 NA NA 1.9713e+03 3418.70 6137.10 NA NA
SDVFAAGT 113270.0 80879.00 79862.00 5709.80 NA 86957.00 70177.00 4908.80 190950.00 45548.00 1.1694e+05 2385.70 NA 106810.00 245400.0 1.8413e+05 106780.00 NA 82300.00 69052.00 64574.00 78157.00 NA 18697.000 1972.300 27218.000 8900.30 33763.000 41293.00 153590.0 3380.50 231900.00 59641.00 22392.00 16053.000 14544.00 30584.000 42825.00 65688.00 495300.00 170290.00 193820.00 38173.0 2732.000 45296.00 3467.7 152940.00 51567.00 177810.0 5.1525e+04 2.5193e+05 NA 6.9761e+03 141750.00 3.9812e+04 7787.90 90825.00 71287.0 46887.00 67397.0 9550.30 14664.000 16047.00 1.3399e+04 117080.00 32012.00 5.9903e+04 62279.000 29485.00 10976.00 31613.00 15020.0 1.3994e+05 295650.00 NA 66189.00 11610.00 128850.00 126490.000 1179.700 24795.00 23912.00 1.6296e+05 2003.90 50301.00 22930.00 51888.00
APHGPGLI NA 11351.00 11168.00 8409.00 1.7052e+04 NA 948.10 NA NA NA NA NA 5995.80 6466.60 NA NA NA NA 744.98 NA 5980.30 NA NA 2261.300 9741.200 2690.900 NA NA NA 15006.0 19162.00 101090.00 16422.00 23439.00 4689.700 NA 11628.000 NA NA 16087.00 9411.70 11381.00 95915.0 4583.400 NA NA NA 9306.00 3696.0 1.3388e+03 1.1051e+04 NA 1.7504e+04 NA NA NA 16592.00 15711.0 7465.80 55880.0 7213.60 NA NA 7.5446e+03 NA 3107.20 2.4681e+03 3668.600 17711.00 3169.80 2204.00 23305.0 8.9113e+03 18709.00 23317.00 4756.50 81245.00 6972.50 13185.000 6340.700 6912.90 NA 3.4270e+04 604.93 NA 12874.00 NA
PVVPVHL NA 21616.00 NA 16749.00 NA 7936.30 10981.00 NA 19031.00 NA 6.1454e+03 21925.00 7949.80 28595.00 NA NA NA NA 7187.90 3667.00 991.14 201.02 NA 13488.000 5890.200 6182.100 NA 547.750 32565.00 10282.0 56833.00 13736.00 5317.90 5739.80 10316.000 5847.20 18663.000 23560.00 13832.00 NA 19174.00 20711.00 32564.0 2662.900 NA 10489.0 NA 20629.00 5036.6 2.7124e+04 5.9789e+03 NA 1.0579e+04 3809.40 NA 50318.00 3832.10 NA 6203.50 25004.0 1557.70 29404.000 12454.00 NA NA 16786.00 5.1467e+03 32338.000 4392.40 1159.10 2213.70 6594.6 3.4743e+04 4228.80 24660.00 32857.00 27310.00 6909.00 81217.000 12127.000 3347.00 14664.00 4.0766e+03 11506.00 9499.90 31995.00 3257.40
KPALPAGT 39085.0 1492.30 18654.00 NA NA NA 12265.00 NA 4272.70 14188.00 3.7494e+04 NA 1318.50 2576.70 39366.0 8.7873e+03 376.61 NA 23569.00 26331.00 20460.00 9946.00 36625.00 3564.300 4580.300 4695.300 4481.80 2412.900 NA 3826.9 NA 2148.30 NA NA NA NA NA NA 2187.40 2572.20 NA 1755.90 NA NA NA 129270.0 NA NA 34128.0 9.9467e+03 8.3467e+04 26819.00 4.3992e+04 27408.00 1.5774e+04 28557.00 8439.30 7459.3 NA 38845.0 4922.60 NA 7431.50 6.8031e+03 2998.90 1431.00 3.7137e+03 NA 14470.00 6635.20 4776.70 NA 2.3311e+03 3188.00 NA 11929.00 7076.10 454.59 NA NA NA 4685.50 NA NA 3642.70 NA 3383.70
APHGPGL 49546.0 NA 115750.00 5449.80 6.4930e+03 NA NA NA NA NA NA NA NA 5183.00 NA NA 3820.00 NA 7304.00 NA 7385.60 1819.00 NA 2304.600 13091.000 1253.700 NA 2922.600 2835.00 15725.0 12996.00 126080.00 9622.50 20563.00 3637.300 4605.30 5482.500 6969.30 NA NA 3201.90 5093.80 50061.0 4873.200 39.25 31923.0 NA 6322.90 NA 1.4544e+04 NA 2645.20 NA 1504.00 NA NA NA 9580.1 NA NA 5741.80 2907.800 NA NA NA 2919.20 4.9149e+03 6073.400 10113.00 1636.90 1270.50 6722.3 NA 4587.50 12544.00 NA 39162.00 4700.40 12342.000 8210.800 2612.50 2657.60 2.0663e+04 1640.40 4995.00 3319.40 NA
AGPSSPT NA NA NA 1062.90 3.7274e+03 3036.30 NA 415.59 15181.00 14034.00 NA NA 3874.00 1279.20 85724.0 3.2545e+03 NA 126.570 NA NA 6710.60 21840.00 16976.00 1373.500 407.040 4994.100 NA 541.710 NA 8133.8 8623.90 3102.00 7721.00 14783.00 NA 1068.90 NA 8087.20 21710.00 NA 10968.00 691.61 47806.0 334.260 217.43 22827.0 NA NA 35767.0 NA 8.3494e+02 NA 5.9103e+03 NA 3.7768e+04 6836.60 6542.20 9745.3 NA NA 996.06 75.888 NA NA 11855.00 595.57 6.7822e+03 634.690 NA NA NA NA 5.4609e+03 2231.70 5101.20 20770.00 11205.00 NA 6370.400 7303.700 NA 14622.00 1.1477e+04 NA NA 6722.40 NA

Three step data processing:

  • Missing value imputation
  • Log2 transformation
  • EigenMS normalization

There is a fair amount of missing values in the dataset, which is typical for MS data in general and untargeted LC-MS proteomics. Missing value imputation was accomplished using KNN.

There are potentially three main reasons behind missing values in mass spec data:

  • Feature is not present in the biological sample

  • Feature is present in the sample but the concentration is below limit of detection

  • Feature is present in the sample and above limit of detection but was not annotated as a peak during deconvolution process

Code
### Use this to count the missing signal values by feature
d1$nacount <- as.matrix(apply(d1, 1, function(x) sum(is.na(x))))

#write.csv(d1, "Unnormalized peak areas/missingtotals.csv")

d2 <- d1[which(d1$nacount < round((length(d1)-1)*.5)), ]
d2 <- as.data.frame(d2[,1:length(d2)-1])
#sum(is.na(d2))
#[1] 5084

imputed_meta_d1 <- impute::impute.knn(as.matrix(d2),k = 7, rowmax = 0.5,
                              colmax = 0.8, maxp = 1500)

imputed_d1 <- as.data.frame(imputed_meta_d1[["data"]], colnames = TRUE)


hist_impute <- ggplot_truehist(unlist(imputed_d1), "After imputation")
qq_impute <- ggplot_carqq(unlist(imputed_d1), "After imputation")
#pca_impute <- ggplot_pca(imputed_d1, labels_d1, "class","After imputation")
Code
plot_grid(hist_impute, qq_impute, nrow = 1)

As is shown above, data after imputation is not normally distributed, therefore log2 transformation is the next step.

Data transformation applies a mathematical transformation on individual values themselves. For mass spec data, log transformation is a good choice, as it reduces or removes the skewness of mass spec data.

Code
log2_d1 <- log2(type.convert(imputed_d1)) ## log2 transformation
# save data
#write.csv(log2_d1, file.path(WORKING_DIR, "log2_transformed.csv"))

# draw histogram
hist_log2 <- ggplot_truehist(unlist(log2_d1), "Log2 Transformed")
qq_log2 <- ggplot_carqq(unlist(log2_d1), "Log2 Transformed")
pca_log2 <- ggplot_pca(log2_d1, anno, "Label","Log2 Transformed")
Code
plot_grid(hist_log2, qq_log2, pca_log2, nrow = 1)

Code
# display table
log2_d1 %>%
        mutate(across(everything(), round, digit=2)) %>%
        knitr::kable(., digits = 3, "html") %>%
        kableExtra::kable_styling(bootstrap_options = c("striped", "hover", "condensed", "responsive")) %>%
        kableExtra::scroll_box(width = "100%", height = "500px")
sample_1 sample_2 sample_3 sample_4 sample_5 sample_6 sample_7 sample_8 sample_17 sample_18 sample_19 sample_20 sample_21 sample_22 sample_23 sample_24 sample_33 sample_34 sample_35 sample_36 sample_37 sample_38 sample_39 sample_40 sample_49 sample_50 sample_51 sample_52 sample_56 sample_57 sample_58 sample_59 sample_60 sample_61 sample_62 sample_63 sample_72 sample_73 sample_74 sample_75 sample_76 sample_77 sample_78 sample_79 sample_9 sample_10 sample_11 sample_12 sample_13 sample_14 sample_15 sample_16 sample_25 sample_26 sample_27 sample_28 sample_29 sample_30 sample_31 sample_32 sample_41 sample_42 sample_43 sample_44 sample_45 sample_46 sample_47 sample_48 sample_53 sample_54 sample_55 sample_64 sample_65 sample_66 sample_67 sample_68 sample_69 sample_70 sample_71 sample_80 sample_81 sample_82 sample_83 sample_84 sample_85 sample_86 sample_87
FAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 18.88 13.82 15.51 11.77 15.49 12.61 16.19 12.58 16.18 14.87 18.40 15.21 14.09 15.16 17.62 18.25 12.01 11.12 14.63 15.52 16.21 16.71 16.82 15.05 14.31 14.42 14.83 13.54 17.37 17.07 17.78 19.03 18.74 17.23 11.28 10.61 12.64 16.90 17.40 19.51 17.71 16.38 15.41 10.50 12.99 20.32 12.10 13.74 16.05 19.77 16.97 18.54 16.94 17.06 18.45 13.07 15.21 15.75 14.51 17.72 14.69 13.17 14.24 15.23 17.82 15.70 15.69 14.20 17.66 16.34 14.65 20.47 19.24 19.23 17.77 17.71 19.07 16.08 16.18 13.69 14.76 18.34 17.32 15.62 17.05 16.18 18.08
EEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 20.26 17.16 16.46 15.19 14.72 15.87 17.19 14.59 15.60 16.22 19.35 16.75 15.58 15.75 19.51 19.48 8.57 13.71 18.82 17.88 18.35 18.54 18.48 16.88 15.70 16.78 16.10 14.49 19.73 19.09 19.39 19.92 19.92 18.84 15.95 15.50 16.38 18.89 19.82 21.73 19.85 18.48 19.79 16.70 16.38 21.23 14.71 17.10 18.80 20.37 18.81 19.37 19.63 18.47 19.34 16.19 16.59 18.33 17.14 19.23 17.53 15.56 14.72 18.26 18.34 16.09 14.97 16.78 19.75 17.55 14.07 21.14 20.76 20.74 19.78 19.75 21.24 17.99 18.97 16.68 18.02 20.74 19.53 17.61 19.69 19.93 20.03
DADLADGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 18.86 15.26 17.23 14.98 14.60 14.17 16.43 12.03 16.15 15.55 19.54 16.03 15.06 15.96 11.48 17.90 11.22 10.94 16.90 16.88 16.37 17.36 17.37 14.50 14.12 15.34 15.74 13.57 17.73 17.22 18.13 17.86 17.48 16.79 12.16 9.48 11.50 17.93 18.67 18.85 17.92 15.28 18.09 13.64 13.76 19.65 14.12 14.72 18.67 18.84 18.14 18.96 19.41 18.80 18.99 15.57 16.41 17.14 16.11 18.15 16.49 13.81 15.89 16.34 18.86 15.65 16.39 14.41 17.24 17.01 15.13 19.56 18.95 19.48 16.98 18.46 18.29 16.14 16.04 15.18 15.99 18.54 17.61 15.63 17.71 17.83 18.33
GRPEAQPPPLSSEHKEPVAGDAVPGPKDGSAPEVRGA 16.56 14.76 15.89 15.09 13.74 12.00 13.78 12.82 15.28 14.85 17.67 14.42 13.38 14.51 16.21 15.95 12.75 11.06 15.12 14.16 15.95 16.85 17.00 12.14 12.29 13.57 15.25 12.91 14.62 15.38 16.77 16.51 16.45 13.58 13.28 11.65 11.61 14.89 16.71 16.37 14.98 13.49 16.73 13.17 12.90 18.73 12.31 15.41 16.55 17.78 15.19 15.89 15.04 15.98 17.02 15.26 15.59 14.31 14.81 15.56 14.39 12.40 14.71 13.90 19.00 13.90 14.94 12.46 16.85 18.71 16.53 18.32 18.34 17.71 14.73 15.64 15.03 13.77 14.62 12.97 13.05 17.26 17.37 12.71 15.05 12.91 17.40
DLADGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 16.78 15.03 14.99 14.08 13.40 14.46 14.10 11.01 15.03 14.16 17.04 13.92 13.25 13.46 16.22 16.42 12.33 11.81 15.05 14.91 15.36 16.18 16.03 12.98 13.29 14.60 14.34 13.63 16.45 15.95 16.63 16.22 15.82 15.70 13.84 13.30 13.52 15.98 17.42 17.86 16.48 14.11 17.36 13.00 13.14 17.55 13.73 14.21 16.58 16.49 15.81 16.56 15.16 16.24 16.36 14.30 14.33 15.35 14.69 16.36 15.24 13.91 15.06 14.92 17.78 14.28 14.85 13.26 16.35 16.16 13.00 18.59 17.96 18.29 16.05 15.54 17.08 14.46 14.12 13.45 14.49 17.66 15.89 14.46 16.55 16.59 17.28
FAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRA 18.87 17.18 17.34 17.58 15.45 16.27 17.83 15.40 16.47 15.34 20.05 14.81 15.78 15.84 19.40 17.50 13.08 12.86 17.98 16.26 18.08 19.18 18.56 17.67 17.42 15.98 17.59 16.56 18.48 18.81 19.78 20.36 20.28 19.63 16.07 14.92 15.79 19.42 19.26 20.06 19.01 17.71 18.36 16.03 16.32 20.53 16.24 17.20 18.66 19.76 18.67 18.75 17.68 17.85 19.13 15.08 15.20 16.85 15.66 19.19 17.34 15.36 17.21 17.08 18.84 17.29 16.63 16.67 19.10 19.02 16.61 21.01 20.10 19.31 18.38 17.44 18.77 18.05 18.16 17.20 18.34 17.87 17.93 16.63 17.59 17.07 19.73
AVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 15.69 14.67 15.91 13.22 13.22 14.34 13.57 10.71 14.88 13.92 17.39 14.27 13.05 13.54 15.86 13.31 11.27 12.40 15.06 14.67 14.14 14.31 16.01 12.88 13.22 13.78 15.44 12.85 16.45 14.85 17.35 14.80 16.28 12.47 13.87 11.74 13.42 15.17 17.26 16.72 14.64 12.92 15.08 13.13 13.66 17.10 14.73 13.60 14.84 16.70 15.90 15.04 15.14 14.58 16.82 14.65 14.76 14.38 14.38 15.09 12.17 13.44 14.69 15.07 14.97 13.08 14.59 12.75 14.62 14.45 12.26 19.13 16.38 15.92 14.58 13.92 15.85 13.84 15.04 12.62 11.95 15.53 15.01 13.06 16.49 15.26 15.42
VADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 15.84 13.96 15.78 13.79 12.53 12.40 13.90 10.35 14.02 12.01 14.35 11.99 11.67 13.25 18.84 13.86 11.99 11.41 13.31 13.65 12.31 12.41 13.41 11.63 13.95 12.08 13.58 13.20 14.85 14.47 15.26 16.27 15.73 14.59 12.38 12.70 13.02 13.02 15.04 15.68 13.13 14.38 16.03 12.55 12.89 17.20 12.01 14.50 14.67 17.05 14.10 14.89 15.62 14.19 14.28 12.60 14.93 12.53 9.77 16.22 12.07 12.67 10.91 11.07 10.98 10.43 15.38 11.82 15.59 11.82 11.27 17.70 14.93 15.23 14.78 17.13 16.79 11.27 15.00 13.24 13.25 14.97 15.21 11.08 13.22 15.04 15.15
EEKAVADTRDQADGSRASVDSGSSEEQGGSSRA 19.29 17.91 16.84 17.22 14.69 16.91 18.55 16.27 16.01 16.36 20.28 15.29 16.77 15.60 18.88 17.84 14.73 15.31 19.17 18.58 19.65 19.53 17.66 17.16 16.13 17.14 18.94 16.30 18.15 18.30 19.08 19.49 19.20 19.19 15.30 17.27 14.14 18.36 18.72 20.73 19.78 16.67 19.91 17.01 16.45 20.42 16.25 17.60 19.51 18.87 18.63 17.94 18.06 17.72 18.83 14.77 16.14 18.00 15.73 18.51 18.06 15.78 17.76 18.35 17.42 18.35 18.53 17.92 17.88 17.97 16.06 20.20 20.09 19.57 17.89 19.45 19.97 17.33 17.23 18.35 18.74 18.58 18.69 17.90 17.95 18.27 18.76
DGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 18.59 16.25 16.48 15.88 13.31 14.30 16.66 11.75 16.18 15.55 19.10 15.92 15.40 16.72 18.31 18.06 11.87 12.52 16.46 17.21 17.18 18.29 18.20 14.74 14.72 15.88 16.40 13.80 18.68 18.27 18.96 18.62 18.40 17.64 13.99 14.33 12.83 18.53 19.56 19.95 18.44 16.54 19.42 14.02 14.49 19.31 15.23 15.91 18.34 18.89 18.25 18.76 18.24 18.27 19.03 15.71 16.91 17.43 16.08 17.99 17.17 14.74 16.03 15.91 19.62 15.50 16.36 14.49 18.39 17.93 15.06 20.33 19.77 19.55 17.95 19.75 19.40 16.74 16.84 16.08 17.00 19.08 18.29 16.83 18.79 18.63 19.40
IAVEWESNGQPENNYKTTPPVLDSDGSF 13.80 10.66 19.43 12.41 12.77 10.76 14.62 11.28 15.18 11.73 17.58 14.46 13.66 14.67 15.99 15.99 10.90 12.27 14.95 15.21 17.00 17.37 15.46 12.26 9.07 5.85 15.07 12.61 14.30 14.10 14.45 14.25 13.74 12.03 12.76 13.13 12.97 14.71 14.45 13.86 15.68 14.09 16.88 12.46 13.43 13.57 11.71 13.73 17.74 10.38 16.30 15.42 17.06 14.62 15.56 12.56 14.63 15.50 15.98 10.10 14.48 10.65 13.45 16.76 12.57 13.28 15.37 10.68 13.51 15.98 13.90 13.54 13.34 12.93 7.95 14.08 14.84 11.87 14.56 12.60 6.88 13.76 14.08 10.50 13.90 14.42 14.39
EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ 15.59 13.22 14.27 11.61 9.42 12.57 15.14 13.81 11.02 17.01 17.47 16.04 14.96 15.77 18.92 19.99 12.13 10.92 16.76 15.74 18.05 19.94 18.61 16.42 14.68 17.52 18.57 16.81 14.71 16.45 14.25 17.26 15.82 15.03 8.76 11.44 13.47 14.37 15.03 13.26 14.49 13.54 16.88 12.94 12.85 14.99 13.96 14.77 17.89 15.75 18.89 12.03 16.10 15.65 19.30 16.37 15.98 16.29 14.72 15.41 16.78 14.24 14.59 16.99 15.31 17.83 19.89 16.05 16.91 19.03 16.94 13.06 14.85 13.25 12.04 14.39 11.85 15.74 11.41 14.34 13.54 14.78 14.41 15.16 15.71 13.46 16.17
TWLNPDPSQKQNLLAPQNAVSSEETND 18.69 14.35 16.94 13.87 5.55 13.32 14.99 10.62 7.78 11.14 15.99 13.94 10.65 11.34 13.90 14.02 11.54 5.64 12.69 12.66 14.29 15.65 14.62 12.03 6.74 9.44 11.57 10.73 10.90 12.35 14.13 13.46 14.54 10.60 13.27 11.85 13.46 15.24 13.68 10.97 13.56 13.40 13.83 13.44 9.44 17.65 9.23 13.94 11.77 14.77 15.61 15.86 15.44 15.77 13.74 13.91 12.53 14.07 16.93 15.36 14.08 12.83 12.67 14.47 12.76 12.09 14.38 4.44 14.19 13.66 12.45 12.01 14.42 13.24 13.10 17.13 13.59 11.15 14.25 11.56 9.60 13.64 13.96 9.41 13.06 14.70 11.57
AIPVAQDLNAPSDWDSRGKDSYETSQL 19.02 12.20 16.71 10.76 11.74 10.80 13.59 10.75 11.67 11.74 15.33 13.55 13.48 12.16 15.35 14.60 11.93 4.98 13.24 14.01 13.54 12.52 11.89 11.15 10.29 12.50 10.70 9.60 14.06 12.58 15.62 17.03 16.35 14.74 12.04 7.04 12.72 13.82 14.66 11.92 14.13 11.30 13.73 12.89 10.28 18.09 11.48 7.80 16.12 15.02 14.76 15.86 13.85 15.25 11.26 15.19 13.79 14.88 13.89 15.20 12.73 12.61 9.20 12.50 13.41 12.67 12.48 10.92 14.59 12.67 9.65 15.70 6.25 16.21 11.64 12.48 14.95 13.50 9.43 12.19 10.25 13.72 14.59 7.28 12.00 13.35 14.16
LAQELPQQLTSPGYPEPYGKGQESSTD 15.95 13.20 14.37 11.23 8.62 9.05 13.92 10.80 12.36 8.47 14.86 13.24 12.32 13.54 13.24 13.34 7.35 9.57 13.87 13.59 12.66 12.82 11.93 12.28 10.59 13.34 11.86 9.99 12.44 12.76 13.32 13.97 12.31 11.68 10.24 11.60 10.72 12.94 11.77 12.66 12.35 13.17 14.03 11.04 12.20 16.41 10.36 12.47 15.04 16.31 14.97 13.65 14.18 13.37 14.07 14.15 13.04 13.75 14.02 14.14 13.75 10.22 11.41 13.30 16.99 11.54 12.36 10.68 14.32 12.87 11.98 12.70 13.70 13.15 13.64 11.26 13.84 10.95 11.06 11.47 11.76 13.43 13.63 12.09 13.27 13.69 12.96
WLNPDPSQKQNLLAPQNAVSSEETND 18.03 13.72 11.29 13.62 13.52 13.27 14.36 10.35 15.05 13.52 15.07 13.11 8.27 14.21 13.46 13.25 11.74 11.80 12.48 13.17 14.22 14.94 14.05 11.59 9.46 12.79 11.55 10.73 13.17 12.26 13.20 12.85 13.24 12.92 13.14 11.66 13.53 14.68 13.27 11.69 13.18 10.67 12.14 12.79 13.41 17.10 12.47 13.95 14.73 10.28 15.03 14.55 13.79 14.57 11.65 12.97 12.10 14.09 11.20 14.85 13.81 12.93 11.56 10.81 11.61 11.24 13.65 12.64 14.88 13.21 11.95 11.37 13.63 12.96 14.19 14.31 13.23 11.74 14.03 10.79 10.87 12.89 13.74 13.33 11.97 14.65 10.66
IPVKQADSGSSEEKQLYNKYPDAVAT 22.10 19.10 19.89 15.71 14.53 14.67 17.11 13.28 19.26 17.01 20.92 16.44 15.62 18.43 19.54 19.17 13.61 7.68 17.52 19.04 19.15 20.01 20.15 16.21 15.77 18.44 17.26 14.46 18.26 17.97 18.73 18.94 19.34 16.61 13.07 14.22 13.32 19.85 20.27 20.18 20.22 16.36 19.58 14.56 15.20 21.31 16.96 16.24 21.82 19.79 19.07 19.81 19.51 20.54 19.27 18.38 17.20 18.78 17.21 20.19 18.37 14.11 15.94 18.88 19.33 16.50 20.19 14.48 19.28 18.14 16.57 19.28 20.19 20.76 19.55 20.12 20.08 17.44 16.97 17.52 17.19 19.38 19.85 16.09 19.63 19.95 18.51
EAEDLQVGQVELGGGPGAGSLQPLALEGS 15.37 14.03 15.73 13.14 12.97 13.11 11.99 12.11 13.91 14.43 13.22 12.86 10.85 13.29 15.05 15.25 11.14 8.60 13.98 11.16 15.09 16.88 14.85 13.89 11.37 14.90 15.72 14.48 11.12 12.39 15.47 13.36 11.71 11.02 12.73 9.29 12.54 10.31 14.85 13.56 9.51 10.83 16.68 12.71 13.37 15.14 16.23 14.48 18.65 15.85 15.19 14.48 15.86 10.20 15.75 14.02 13.35 13.50 15.89 13.53 14.29 12.14 12.22 14.16 13.86 15.10 16.49 13.62 13.62 15.59 13.88 13.51 13.61 13.77 14.71 13.45 14.53 13.23 14.56 12.17 11.02 13.38 13.87 12.65 11.64 15.06 12.05
TAQLDEELGGTPVQSRVVQGKEPAHL 16.83 13.42 15.09 10.90 14.18 13.01 12.96 12.83 11.31 12.48 18.30 12.56 13.31 13.99 15.78 15.88 10.18 12.03 14.48 14.65 15.50 15.59 14.23 12.02 12.80 13.93 10.75 10.13 10.50 14.61 16.69 17.97 17.10 15.60 13.02 12.85 13.53 15.66 15.86 15.61 13.92 12.26 15.62 13.02 13.49 16.37 16.23 14.43 16.86 17.75 16.30 13.11 14.40 15.48 16.91 14.96 15.19 15.64 9.77 16.86 15.63 13.15 12.19 12.75 13.12 10.70 13.99 11.73 16.40 16.23 15.45 19.23 16.30 16.15 13.97 13.40 15.79 12.03 14.00 13.50 12.69 15.69 16.36 11.70 13.06 13.33 15.64
IPVKQADSGSSEEKQLYNKYPDAVA 22.84 14.43 13.87 14.62 13.65 14.14 18.90 11.95 12.30 15.88 22.05 17.98 14.79 16.71 19.98 20.02 9.39 11.95 18.23 18.45 19.72 20.65 20.66 16.64 15.51 15.37 17.40 11.61 18.84 18.97 20.18 19.96 20.73 17.68 9.59 11.19 10.90 20.93 21.16 20.01 20.97 17.10 18.40 9.56 14.21 22.14 14.36 15.03 15.01 20.78 19.84 20.68 20.72 21.29 20.17 19.08 15.95 19.10 17.83 20.57 18.94 15.22 17.16 10.25 20.20 17.87 11.53 14.63 19.43 19.31 17.80 20.34 21.21 21.48 19.66 21.72 20.93 18.00 17.93 18.84 17.53 20.43 20.62 16.71 20.40 21.07 19.13
AQLDEELGGTPVQSRVVQGKEPAHL 16.16 13.77 15.09 13.39 14.53 13.16 12.51 12.32 10.83 12.34 17.43 12.47 13.35 13.00 15.04 14.54 12.02 12.24 12.92 13.08 14.42 14.48 12.72 11.24 11.31 12.98 12.55 13.33 14.52 13.97 15.87 17.31 16.05 14.88 12.67 12.95 13.44 14.64 14.59 14.81 13.59 13.23 15.81 12.75 13.66 16.57 12.24 14.46 16.59 16.86 15.16 13.48 14.55 14.77 16.24 13.74 14.34 15.32 9.77 16.14 14.80 13.40 12.19 14.43 10.05 9.91 13.36 12.52 15.45 15.24 14.40 18.47 15.35 15.53 13.75 17.13 15.67 12.58 14.33 11.92 11.68 14.18 15.45 13.46 13.21 13.20 14.97
VKQADSGSSEEKQLYNKYPDAVAT 19.49 17.30 17.10 13.73 13.78 12.29 17.35 13.31 17.87 15.82 17.49 14.05 14.79 17.47 16.68 17.99 11.37 8.68 16.41 17.06 17.47 19.09 18.25 14.57 14.18 16.20 16.03 14.39 16.17 17.71 17.45 17.74 18.46 15.89 13.27 12.42 12.64 18.95 18.05 18.04 18.19 15.21 17.75 13.69 12.83 18.64 13.57 16.14 18.84 16.49 17.88 17.90 15.80 18.04 13.56 16.34 14.68 17.39 15.82 18.31 17.46 13.70 15.00 17.10 16.10 14.19 18.09 13.25 17.53 15.96 14.31 17.56 18.71 17.91 16.94 16.22 18.26 15.82 16.56 14.93 16.18 18.27 18.52 14.59 17.44 18.66 17.18
LSDPEQGVEVTGQYEREKAGFSW 18.10 14.26 17.28 9.09 13.87 12.18 15.28 11.76 12.00 13.39 19.34 9.49 13.69 14.00 15.43 15.56 12.09 12.11 15.92 14.66 14.28 15.48 14.13 10.65 13.20 12.59 13.60 12.91 13.19 16.07 15.84 16.74 16.79 13.25 13.80 11.71 13.48 16.38 17.48 19.01 16.05 13.28 14.39 13.31 11.67 18.96 10.10 14.01 17.57 17.98 17.05 18.02 16.30 16.89 17.87 14.49 14.57 15.15 13.93 17.75 14.55 12.98 12.22 15.62 14.77 12.23 12.29 13.15 16.39 13.48 11.77 17.76 15.94 17.85 14.42 16.73 16.99 12.68 8.83 12.48 8.36 16.48 17.20 13.40 15.51 15.38 16.39
MVEHTPDEESIDWTKIEPSVNF 17.10 14.75 15.09 13.80 13.84 13.50 10.98 10.16 11.02 13.33 17.81 13.93 13.60 13.83 15.79 13.13 12.09 12.01 13.48 15.62 14.81 15.18 15.98 14.04 13.24 13.12 13.21 12.96 13.40 13.70 14.79 14.86 15.57 12.68 13.80 11.97 13.53 14.26 15.76 16.36 13.48 12.04 13.33 13.20 13.47 17.53 13.65 14.28 17.17 16.51 15.81 16.20 14.37 15.91 16.57 10.38 14.99 15.13 13.99 13.95 13.78 13.42 13.56 14.78 17.53 11.30 11.97 12.85 15.84 14.98 12.58 17.51 15.29 16.63 13.26 15.36 15.57 13.08 14.60 12.98 9.42 15.18 14.15 7.74 9.57 13.25 14.73
AQDLNAPSDWDSRGKDSYETSQL 12.63 17.27 17.41 13.02 11.82 10.61 14.00 10.07 16.89 14.23 12.42 12.66 10.81 16.53 10.11 12.64 10.87 11.08 13.42 15.84 15.11 12.11 10.05 13.72 13.30 16.14 12.18 14.02 14.38 15.80 11.79 17.17 14.69 13.39 10.71 9.83 11.65 12.40 16.76 13.15 11.28 13.91 20.37 13.70 9.98 16.21 14.07 12.37 19.76 14.46 9.56 15.43 14.64 13.88 13.27 13.66 14.07 14.53 16.93 17.29 15.38 13.59 11.37 17.02 13.26 15.05 16.54 12.33 14.63 14.78 13.08 12.34 16.21 12.76 14.71 14.80 13.37 14.26 13.06 13.51 14.81 14.98 16.72 12.97 12.42 13.74 16.21
EDPQGDAAQKTDTSHHDQDHPTF 18.49 14.65 15.96 13.98 13.07 13.57 13.32 10.91 14.75 13.84 17.35 13.33 13.33 14.36 16.05 15.91 12.26 11.04 14.76 15.27 14.73 13.30 13.96 13.99 12.87 14.72 14.49 13.23 15.41 16.29 16.64 17.40 16.87 13.80 13.04 10.71 11.64 15.37 16.63 16.84 16.50 15.66 17.69 13.07 13.23 17.53 13.73 13.82 17.97 17.37 15.26 18.03 16.31 16.17 15.02 15.17 13.94 14.84 14.19 16.52 13.87 12.99 13.80 17.17 15.68 12.49 15.34 11.55 14.67 14.32 12.67 17.39 17.48 17.74 16.92 17.32 18.63 13.98 15.71 15.76 13.32 17.77 17.24 12.95 17.05 16.86 16.06
IPVKQADSGSSEEKQLYNKYPDA 19.47 15.86 18.03 13.49 14.55 14.79 16.43 13.70 13.68 13.56 18.06 15.60 13.81 12.48 16.37 14.99 13.27 11.34 15.45 16.21 16.52 17.41 17.70 14.54 14.86 14.23 14.07 13.42 16.12 15.54 17.59 17.38 17.01 15.25 12.39 13.50 12.69 18.34 18.00 16.70 17.94 13.04 19.84 11.80 15.44 18.94 12.46 15.20 16.83 17.69 15.62 18.42 17.34 17.28 15.91 14.52 12.93 15.41 13.80 15.70 16.08 15.03 14.87 11.85 16.80 15.87 13.85 13.47 16.59 16.21 14.85 17.08 17.44 18.17 17.54 18.66 18.04 15.75 15.99 17.10 14.99 16.87 17.29 14.62 17.70 18.73 15.75
LSRQELFPFGPGQGDLELEDGDD 15.48 14.65 13.72 13.01 13.69 13.95 12.06 12.30 11.88 13.10 16.34 12.30 13.66 12.37 15.64 14.48 9.26 12.71 13.97 13.92 14.69 15.09 13.98 12.27 12.78 13.16 11.77 11.43 10.75 12.31 11.89 14.08 13.85 12.68 14.19 11.92 14.16 13.50 13.60 13.65 13.28 13.40 14.92 13.44 13.62 14.72 16.23 15.19 15.63 15.15 14.93 14.20 13.63 14.60 15.66 14.68 12.20 14.10 13.31 15.38 13.81 13.21 12.63 13.80 11.61 11.69 14.77 7.03 12.52 14.52 13.88 15.01 13.96 13.87 14.56 14.34 14.11 11.31 14.58 10.90 11.80 14.40 13.40 8.52 12.67 14.10 14.65
VKQADSGSSEEKQLYNKYPDAVA 19.87 12.98 18.03 14.87 14.37 13.31 17.49 12.43 16.27 15.84 18.58 14.62 14.86 14.50 16.92 17.61 13.48 8.55 16.44 16.24 17.66 19.51 18.67 15.21 13.67 13.30 15.81 15.10 16.86 18.38 18.67 18.45 19.50 17.12 10.30 13.10 12.01 19.75 19.21 17.48 18.63 16.04 15.95 11.69 14.02 18.95 15.08 15.22 18.40 17.67 18.16 18.23 17.76 18.32 15.36 15.82 13.57 17.08 15.51 17.52 17.23 13.89 16.15 16.87 16.75 15.24 11.36 13.78 17.66 16.08 15.14 18.28 19.43 18.06 17.22 17.65 18.51 16.77 17.12 15.98 16.53 18.93 19.07 15.05 18.36 19.33 17.61
EAEDLQVGQVELGGGPGAGSLQPLAL 18.71 13.28 14.39 15.30 13.78 10.15 12.66 9.12 7.74 14.55 17.22 14.13 14.64 14.48 18.53 18.97 9.02 10.84 17.68 13.68 16.76 18.30 18.22 15.27 13.61 16.88 14.77 13.61 16.36 17.76 15.47 18.62 16.58 14.19 10.81 9.98 11.49 14.60 15.56 16.63 14.60 16.18 17.01 12.21 12.60 17.81 14.36 11.32 17.56 18.83 18.02 14.16 18.48 16.90 19.75 15.08 15.46 17.18 10.25 15.55 16.16 13.50 10.99 17.32 13.81 14.37 15.68 15.32 19.28 16.56 14.90 15.77 14.83 16.00 16.53 13.34 16.65 14.82 14.91 13.38 13.71 16.31 16.07 14.55 17.22 17.87 17.27
IAVEWESNGQPENNYKTTPPVL 19.48 13.64 19.90 12.96 13.29 11.24 14.40 8.78 15.43 11.98 18.92 12.91 12.61 14.77 17.51 17.22 12.49 11.90 17.78 15.95 16.95 17.72 17.50 12.46 11.60 14.84 13.87 7.40 15.74 16.40 17.48 17.55 17.16 13.62 13.96 13.33 14.24 16.22 16.98 18.11 18.03 15.12 15.69 8.86 10.51 19.41 14.55 12.49 19.01 18.96 17.48 18.15 17.72 14.58 17.37 13.87 12.47 17.61 16.54 17.19 15.79 14.04 14.52 18.59 13.93 10.53 13.53 12.01 17.42 15.33 13.75 16.99 16.30 17.50 15.46 15.09 18.19 9.12 12.12 13.31 11.27 18.24 18.34 8.05 15.97 15.60 17.91
AKADAAPDEKVLDSGFREIENK 16.51 14.76 15.03 14.21 13.97 13.73 13.91 12.49 14.72 13.11 16.45 12.66 13.65 13.33 15.05 15.50 12.60 11.99 14.52 14.63 14.58 15.09 13.13 11.92 13.44 13.75 14.59 13.33 14.63 16.12 13.70 16.07 15.36 13.69 14.26 12.46 14.00 15.37 15.43 14.66 15.48 13.51 16.74 13.14 13.33 17.13 11.73 14.61 17.77 16.41 15.75 17.57 14.21 13.80 15.22 14.35 14.75 14.60 16.93 16.57 13.93 13.79 12.72 15.25 16.39 12.38 13.34 13.11 14.35 13.31 10.42 16.80 16.89 17.48 15.93 17.27 16.22 12.47 12.50 13.67 13.37 16.47 15.73 13.58 15.94 15.63 16.07
FKQETLPSKSNESHDHMDDM 18.24 14.19 15.88 14.00 13.07 13.90 16.00 11.93 14.20 14.67 17.04 12.75 14.43 15.50 15.57 15.89 11.92 9.89 15.15 15.25 15.22 16.77 16.12 14.74 13.64 14.65 15.28 12.07 15.81 15.13 17.12 16.50 15.94 15.07 11.14 12.70 10.19 16.92 17.52 18.07 17.42 14.18 18.79 12.40 13.75 17.85 14.31 14.82 16.40 17.40 16.47 17.17 15.89 16.50 15.92 16.37 14.33 15.95 15.39 16.15 15.28 13.64 15.00 15.04 15.26 14.36 11.48 12.69 16.64 15.20 14.14 16.91 17.14 16.26 17.61 18.09 17.51 14.44 15.71 15.30 13.93 15.22 17.67 14.05 15.79 18.58 12.83
DEELGGTPVQSRVVQGKEPAHL 19.43 15.50 16.98 15.61 14.35 9.73 14.97 12.58 16.34 15.03 19.08 15.28 14.16 15.56 15.92 16.75 12.72 8.86 16.36 15.79 16.36 16.17 15.27 14.16 15.79 15.36 15.52 12.40 15.55 17.43 19.23 20.21 18.93 17.80 12.63 13.32 11.64 17.52 18.17 18.26 16.34 16.12 20.09 13.55 13.58 19.37 15.89 14.52 17.41 20.17 17.34 18.08 17.47 17.61 18.27 13.83 15.83 16.78 14.49 18.49 16.90 13.59 13.38 16.86 18.43 12.90 14.91 12.74 18.65 16.69 15.76 21.18 17.95 18.58 17.39 15.86 19.66 14.60 16.01 14.85 15.40 17.18 18.48 14.61 16.25 17.28 17.62
LSDPEQGVEVTGQYEREKAGF 19.15 13.91 18.00 15.74 14.48 14.25 15.49 9.86 13.65 13.73 19.79 9.76 10.51 16.19 17.35 15.45 11.23 9.83 17.96 15.58 14.70 15.45 14.40 11.09 10.93 14.71 15.61 13.95 16.93 19.54 19.12 19.56 19.50 16.20 10.61 11.65 12.30 18.10 19.80 18.78 17.74 16.49 18.67 12.91 13.93 20.49 14.17 11.98 18.48 20.11 17.47 17.17 18.01 17.17 18.27 12.70 14.99 16.06 14.58 18.94 16.29 13.41 11.28 17.63 17.91 14.87 14.58 11.21 18.92 13.99 13.16 19.26 16.31 17.49 16.45 15.03 19.15 15.16 16.30 14.76 14.52 17.06 20.46 14.22 19.22 19.22 18.02
LNAPSDWDSRGKDSYETSQL 17.69 13.81 17.32 12.94 13.07 13.05 15.61 12.85 12.72 14.58 14.96 14.49 14.64 14.61 13.70 15.70 11.14 10.56 14.38 14.58 14.36 14.03 14.82 13.47 13.07 13.63 13.04 12.24 14.80 15.20 16.20 15.84 15.34 13.98 11.27 12.48 12.52 17.09 16.47 16.58 15.99 13.94 16.50 13.23 13.02 17.26 11.16 14.43 15.69 16.23 15.93 16.68 15.51 15.20 14.57 17.31 14.18 14.91 14.75 15.04 14.39 13.35 13.67 15.88 12.93 14.15 14.73 13.02 16.14 13.96 13.49 15.71 16.05 16.42 15.55 16.55 17.46 13.95 15.15 15.00 13.72 15.72 15.84 13.19 16.02 17.60 14.97
FKQETLPSKSNESHDHMDD 17.51 14.08 14.60 14.77 13.26 13.56 14.67 12.47 14.62 14.43 15.44 13.71 13.50 13.84 15.48 16.39 11.71 11.06 14.13 15.09 15.30 15.73 15.56 14.06 13.24 14.30 14.57 13.11 14.99 14.85 16.41 15.23 13.83 14.37 12.45 12.99 12.11 16.40 16.79 17.54 16.55 13.32 17.96 12.16 12.98 17.48 13.57 14.20 16.55 16.93 16.21 16.66 15.86 17.12 15.08 15.60 13.90 15.50 14.74 15.28 14.77 12.45 13.49 13.79 14.36 13.87 12.33 13.00 16.27 14.27 12.30 15.40 15.93 15.49 17.26 16.47 16.51 13.66 15.05 14.07 13.44 14.84 16.20 13.21 16.47 17.61 15.46
EAEDLQVGQVELGGGPGAGSLQP 13.66 13.84 15.46 13.61 10.70 12.54 14.49 9.52 14.14 12.01 14.03 12.16 14.29 14.10 13.49 11.60 13.31 12.21 14.15 14.09 11.89 13.13 11.26 13.65 13.81 14.72 13.31 14.42 13.70 15.07 13.70 16.04 11.89 12.04 11.12 11.20 12.96 10.05 12.71 12.90 11.25 12.70 15.68 11.72 13.21 15.11 12.24 10.90 14.72 14.28 13.72 12.74 14.25 12.21 13.90 10.28 15.32 14.07 14.63 13.20 14.80 14.43 10.09 12.75 13.09 14.38 15.99 13.79 14.97 12.20 13.28 13.08 11.46 13.21 12.88 11.26 14.16 13.69 12.43 11.36 13.15 12.80 13.28 13.99 12.75 13.91 11.69
LVLTGYQVDKNKDDELTGF 17.09 14.73 20.28 14.38 12.48 12.56 16.45 12.26 18.34 10.95 18.08 14.23 13.59 15.54 16.34 15.69 11.19 9.82 16.17 14.70 13.40 14.54 15.77 14.40 13.73 13.58 13.43 14.92 15.58 15.18 16.57 17.41 15.79 13.87 10.44 11.82 13.25 15.97 16.08 15.57 14.38 14.59 15.77 13.14 12.00 17.41 13.85 10.39 17.78 18.29 16.17 16.36 17.25 16.20 13.06 14.91 16.48 15.24 13.18 17.68 16.06 12.94 14.71 15.94 13.51 17.15 13.71 13.50 15.36 14.62 14.25 15.55 15.87 11.56 16.81 12.53 15.77 14.32 13.53 15.71 13.95 15.21 14.33 14.45 14.04 14.77 13.86
VQVFAPANALPARSEAAAVQP 15.64 14.43 14.15 12.81 7.83 13.00 15.90 9.15 16.11 15.53 15.90 14.15 14.71 15.26 14.07 14.50 8.45 12.97 16.18 15.38 15.36 15.27 14.88 15.11 12.12 17.11 14.91 13.53 14.19 13.60 9.95 10.88 11.43 11.93 11.29 10.89 11.61 13.15 13.61 13.11 14.10 13.36 15.80 11.01 12.36 16.22 15.80 14.68 16.08 16.25 16.37 12.62 15.12 13.99 17.02 16.73 16.03 17.39 14.28 17.20 15.52 7.35 14.54 16.18 13.68 14.37 14.07 13.55 16.41 14.85 14.92 13.40 14.77 13.04 14.49 10.80 10.77 13.24 12.10 13.73 12.90 14.68 14.39 12.96 14.76 13.19 13.31
DGQPGAKGEPGDAGAKGDAGPPGP 15.44 14.91 15.51 13.78 8.62 15.27 12.16 11.19 15.13 14.59 14.83 14.36 11.98 12.40 16.27 12.20 11.87 12.43 14.76 15.41 16.07 15.96 14.53 11.48 12.94 14.71 16.20 14.41 15.03 16.71 15.10 15.86 10.35 14.87 11.19 14.80 9.28 14.91 15.80 16.11 14.82 13.95 15.71 9.09 12.83 16.32 14.17 12.88 15.53 16.04 16.63 13.15 16.03 15.23 15.78 14.88 15.07 12.31 14.69 16.81 14.07 14.69 16.24 15.04 15.60 13.98 14.53 13.59 16.01 15.65 12.76 16.52 17.09 16.32 15.20 15.49 15.56 14.21 13.72 13.75 14.88 16.46 16.30 14.61 10.51 15.78 16.42
IILEHHVAQEPSPGQPSTF 16.92 12.83 16.02 11.36 13.75 11.71 13.67 9.86 12.96 12.01 15.84 12.14 12.95 11.82 13.92 14.36 12.13 10.86 14.56 12.88 14.69 14.51 13.05 5.96 10.42 13.81 9.24 13.60 14.19 14.49 14.06 15.14 13.60 13.18 13.00 11.33 13.09 14.25 15.23 15.21 15.33 13.03 15.71 12.14 12.60 17.04 12.46 13.67 16.77 15.81 15.54 13.13 15.62 15.11 16.86 12.47 13.66 14.88 16.93 16.34 14.12 12.71 11.91 13.73 12.90 13.82 13.00 10.90 14.46 14.47 13.05 15.90 15.23 15.43 14.94 12.77 15.62 13.58 13.60 13.65 12.22 15.27 15.40 13.34 14.41 14.66 14.73
DAHKSEVAHRFKDLGEEN 20.54 15.95 21.43 16.67 16.18 15.59 11.49 11.46 14.04 15.58 21.14 12.58 14.45 14.67 20.99 18.13 9.94 5.64 19.36 15.20 17.82 15.87 10.75 10.45 12.13 16.11 14.03 7.91 18.04 18.14 19.97 18.52 19.94 15.36 15.26 15.57 13.02 16.17 19.92 20.93 17.64 15.26 23.17 17.45 13.16 18.74 9.92 16.20 21.71 19.59 18.90 19.69 19.40 17.29 20.42 14.28 19.23 21.23 17.33 20.78 14.17 11.45 12.53 22.91 17.13 14.97 16.36 10.54 18.01 12.55 13.27 20.75 19.43 21.34 19.07 18.95 19.42 15.70 18.02 16.16 12.51 20.98 20.48 15.72 19.09 19.81 16.34
S(+42.01)ETAPAAPAAPAPAEKTPVKK 16.82 14.41 15.03 14.85 12.56 13.81 15.64 11.61 14.95 15.49 16.93 14.58 12.68 14.56 16.36 14.45 12.13 9.60 15.63 15.47 16.31 16.73 15.63 14.26 13.25 15.20 15.32 13.98 15.92 16.18 15.46 16.78 15.83 14.52 12.44 13.95 10.95 15.89 17.08 15.74 15.81 14.73 17.01 12.97 12.44 16.42 14.44 13.38 16.45 16.61 16.03 14.53 16.13 16.15 16.29 13.90 14.25 15.12 14.21 16.05 15.11 12.58 14.43 14.74 16.52 14.19 15.54 13.10 15.94 16.19 13.52 17.28 16.67 17.24 14.57 16.49 16.18 14.82 13.52 14.27 15.15 16.56 15.75 14.72 15.71 15.72 17.00
VVVKLFDSDPITVTVPVEV 17.00 7.92 11.68 13.87 13.89 9.69 12.68 9.86 12.04 15.18 14.17 13.67 6.92 13.04 17.47 17.18 10.08 11.74 14.18 15.83 16.15 14.73 12.97 11.43 6.62 12.38 13.01 9.00 13.27 13.50 14.81 8.66 10.31 8.21 13.30 11.75 13.73 12.90 14.60 12.02 11.26 8.55 14.70 13.13 8.59 16.60 11.88 14.00 15.52 15.32 15.74 15.43 15.59 17.52 13.57 11.50 15.67 14.11 15.68 16.37 11.12 5.78 10.77 10.39 15.62 13.48 14.60 10.28 14.65 14.41 13.36 12.68 12.42 10.97 7.49 11.76 12.42 12.63 14.50 12.67 12.30 14.50 12.44 8.09 9.71 11.18 11.71
S(+42.01)ETAPAAPAAAPPAEKAPVKK 16.41 14.14 16.08 14.46 11.97 12.32 15.25 10.72 13.93 15.32 16.79 15.32 12.45 12.46 16.36 13.93 12.04 9.95 13.93 14.92 15.70 16.06 15.46 13.83 12.45 14.81 14.79 13.35 15.35 15.70 15.26 16.19 14.29 14.21 11.92 13.49 10.76 15.29 16.45 15.57 15.24 14.14 15.90 12.60 11.40 15.81 14.01 12.82 15.72 16.48 15.48 14.07 16.06 15.93 16.04 13.71 14.83 14.66 13.49 16.31 14.55 12.02 13.93 14.04 15.53 13.83 15.08 12.64 15.28 15.57 12.84 16.91 16.22 16.79 13.90 16.33 15.62 14.08 13.39 13.94 14.47 15.99 15.17 14.10 15.29 14.88 16.39
VLTGYQVDKNKDDELTGF 17.55 17.32 20.38 16.06 14.81 13.66 16.23 12.58 18.80 15.37 17.67 13.82 15.57 16.70 16.77 15.60 12.50 13.97 17.83 15.68 12.62 14.95 16.23 15.54 15.76 15.89 14.58 15.21 17.78 16.75 16.90 17.41 16.74 15.01 15.40 15.91 13.69 16.11 17.09 15.94 15.69 16.92 17.90 15.05 14.74 17.72 15.40 15.16 17.55 18.78 16.62 14.06 11.24 15.82 15.17 16.53 17.66 16.96 15.86 18.13 16.70 16.20 15.55 16.94 13.56 18.00 12.14 15.66 16.62 13.95 15.21 16.47 16.60 11.45 18.68 9.98 16.82 15.93 17.28 17.02 16.22 15.47 16.20 15.71 16.05 16.86 14.64
KANDESNEHSDVIDSQEL 17.89 14.44 15.44 12.08 12.40 12.78 13.87 11.29 12.47 14.05 15.80 11.16 12.70 13.44 15.30 13.02 10.96 11.93 14.30 13.73 12.77 14.40 14.50 13.60 13.14 14.05 14.33 12.95 15.31 15.04 15.72 15.72 15.85 13.63 10.80 11.25 11.29 14.78 15.59 15.21 15.87 13.98 16.02 11.93 12.78 16.66 13.11 12.83 14.84 14.76 13.66 13.81 16.12 13.02 14.85 14.40 12.82 13.38 10.71 15.12 14.55 13.14 13.99 13.03 13.49 12.95 14.97 13.01 15.66 12.49 12.79 14.15 14.33 15.01 15.91 11.55 15.72 13.31 15.35 14.37 13.57 13.84 16.22 12.69 16.40 17.94 13.21
ASHTSDSDVPSGVTEVVVKL 13.46 14.17 15.52 12.94 12.67 11.18 12.48 10.75 14.63 13.73 14.12 13.55 13.67 14.11 14.49 14.32 10.92 11.43 13.73 14.85 15.30 15.00 13.13 12.42 12.15 13.11 14.09 12.35 11.71 12.26 13.29 13.21 11.96 11.43 12.14 11.78 12.62 12.40 13.53 12.17 13.02 11.72 16.33 12.12 14.07 13.65 12.29 12.98 14.71 14.07 13.58 11.33 15.36 13.12 13.46 12.97 13.81 13.86 15.83 12.28 12.03 9.84 13.29 14.51 11.34 13.20 15.13 11.58 14.27 14.48 13.08 12.34 12.85 11.66 14.23 11.26 12.80 10.53 13.69 12.72 9.47 11.69 13.52 11.24 11.01 12.72 11.25
AKVQWKVDNALQSGNSQE 20.05 15.34 16.76 15.33 14.29 15.19 17.25 13.40 15.18 15.86 16.72 14.76 13.17 13.33 11.54 17.60 12.61 9.57 14.71 12.29 15.57 15.99 12.93 13.83 11.98 14.10 15.01 7.01 9.64 12.20 16.03 17.89 15.31 13.13 11.06 10.45 12.64 14.41 13.27 15.50 13.37 13.34 21.45 17.61 16.08 19.45 13.13 15.28 17.51 20.59 12.54 17.22 14.29 12.64 15.86 14.87 13.84 15.70 14.55 17.25 11.89 13.28 14.65 14.71 13.41 14.41 15.10 9.01 14.67 10.89 13.60 18.62 18.00 18.19 16.52 17.73 18.81 15.66 13.61 15.38 13.96 14.97 15.41 13.68 13.98 16.04 14.37
VFEIGSPATTNGVVPADVIL 15.09 12.18 7.77 6.82 8.62 9.81 9.38 11.00 12.07 13.13 13.86 13.24 11.81 8.43 12.09 10.48 9.95 9.49 13.38 12.95 8.76 11.03 11.45 10.38 7.85 13.32 12.46 11.99 9.06 10.22 10.29 13.05 11.92 12.05 11.10 11.59 11.37 9.99 10.94 9.25 12.67 10.76 11.61 11.89 15.14 15.63 10.24 11.95 12.79 16.02 11.98 13.57 13.73 13.60 14.37 11.07 10.22 12.78 14.05 13.23 12.30 11.18 12.04 13.08 9.83 11.74 12.71 11.44 13.98 9.91 10.83 12.93 13.58 12.73 10.26 11.26 13.13 11.60 12.61 12.81 11.32 11.36 11.57 12.30 10.72 12.59 12.83
PSDWDSRGKDSYETSQL 17.46 13.79 15.11 13.17 13.08 13.01 14.01 11.62 14.66 13.87 14.45 12.37 14.15 13.80 15.30 13.73 11.14 10.03 12.68 13.31 14.60 13.55 14.30 13.10 12.53 12.97 11.87 10.87 15.02 14.57 13.96 13.16 14.31 12.70 13.08 11.93 9.15 15.18 15.97 15.09 15.27 13.79 17.58 10.14 13.29 17.03 12.69 14.51 12.85 16.45 14.17 15.81 15.13 13.11 13.42 14.90 12.37 13.75 13.51 13.38 13.45 13.13 12.09 14.67 13.10 11.24 10.04 11.65 15.13 11.50 10.49 15.61 13.91 15.52 14.67 14.45 17.27 13.30 15.20 13.09 12.13 14.09 16.01 11.38 16.09 17.44 13.01
FAEEKAVADTRDQADGSR 17.95 15.34 16.52 14.46 12.54 14.44 15.10 11.93 15.37 14.68 17.38 14.24 13.26 15.77 16.90 16.64 12.42 11.06 15.80 16.30 16.44 16.86 14.28 15.66 12.75 14.06 14.16 9.75 16.39 16.93 16.01 17.22 16.61 15.50 10.99 13.05 11.96 17.03 15.90 15.37 16.87 15.46 16.24 13.26 13.70 17.17 14.85 14.62 17.96 16.77 17.05 16.57 14.94 14.96 15.99 14.83 15.02 16.35 14.22 17.29 14.02 13.10 15.20 16.16 15.10 16.07 15.23 12.21 16.18 14.57 13.12 15.74 17.23 16.52 17.06 15.74 17.19 15.78 13.24 15.44 15.19 15.73 16.59 13.83 15.49 14.82 15.79
VVKLFDSDPITVTVPVEV 14.83 12.79 13.78 12.23 9.36 11.80 12.93 11.16 8.99 12.74 13.01 11.76 13.31 12.53 15.01 14.58 10.41 10.80 13.24 14.11 14.03 14.09 12.16 9.31 7.40 10.33 11.14 10.55 12.18 12.50 13.51 13.07 11.78 12.35 11.97 11.21 12.88 8.98 12.94 12.40 12.86 11.73 15.42 11.93 12.17 15.16 10.24 12.49 15.01 14.28 13.91 13.48 14.50 15.23 12.43 9.25 12.53 13.06 13.42 14.64 10.65 11.27 9.99 11.58 12.82 10.09 12.75 11.75 12.61 12.03 11.50 12.24 10.72 12.81 8.52 17.13 11.49 11.06 13.41 11.43 11.88 12.46 10.35 11.76 10.06 9.30 10.54
QVGQVELGGGPGAGSLQPLAL 15.16 11.89 14.08 10.22 8.62 7.04 10.58 11.00 12.19 14.10 15.53 16.17 12.70 11.69 12.27 10.54 10.50 8.12 13.33 13.26 8.05 11.04 11.56 10.38 10.64 11.60 12.12 7.83 9.83 11.47 12.32 13.08 12.34 12.16 10.97 11.59 11.35 11.43 12.38 11.90 12.80 11.14 14.05 10.78 15.14 14.65 10.24 11.50 12.69 16.66 13.52 13.59 14.57 13.76 15.03 12.55 12.27 13.47 14.05 14.58 13.20 9.45 12.55 11.16 9.83 7.38 12.66 9.27 15.19 6.79 11.98 11.20 13.42 10.58 12.31 11.26 13.22 11.77 9.70 12.91 11.27 9.95 8.37 12.30 9.93 13.06 11.04
S(+42.01)ETAPAAPAAPAPAEKTPVK 10.75 13.86 18.07 12.71 11.18 10.16 13.07 10.45 15.17 13.73 14.19 12.37 13.48 8.64 10.45 10.36 11.28 10.40 12.53 13.23 13.60 13.72 10.97 12.12 12.15 14.00 13.53 13.93 13.37 13.57 12.02 13.69 12.49 13.03 11.36 12.53 11.08 12.64 13.23 12.13 12.58 12.87 15.32 11.89 13.70 14.25 12.29 12.49 14.18 14.11 13.45 11.18 13.51 12.91 11.91 13.20 13.54 13.39 13.30 12.09 13.97 12.97 13.61 12.98 11.13 13.33 14.57 12.36 13.07 13.36 12.61 10.72 11.66 12.02 13.71 11.26 11.98 13.18 12.59 12.77 12.58 11.91 12.76 13.04 13.25 12.41 12.23
VSEDPINDGEWHRVTAL 17.88 14.06 15.62 12.84 13.08 12.74 13.80 10.92 14.42 13.84 14.11 13.10 13.18 13.54 13.60 13.22 12.60 11.12 14.15 14.46 14.10 12.55 13.06 9.88 10.96 13.76 14.67 13.62 13.62 14.24 14.17 16.40 15.47 12.84 11.88 11.16 12.06 14.70 15.23 17.26 14.39 13.86 18.14 11.77 13.06 18.17 12.24 9.77 14.43 16.39 13.57 13.16 12.41 14.77 11.96 13.87 14.10 12.42 14.74 14.75 12.23 13.14 13.05 13.46 14.53 13.57 15.10 7.78 16.32 12.60 8.37 15.96 14.42 16.54 14.85 13.53 17.97 12.98 14.98 12.71 12.39 14.89 15.01 12.79 13.49 14.64 15.14
FRTQTAPGGQGAPWAEEL 17.89 11.44 16.95 11.18 12.82 13.14 11.23 10.91 14.79 9.36 18.03 12.55 13.01 13.62 14.31 17.19 12.26 11.23 16.06 15.00 16.43 16.20 15.25 12.07 9.90 12.51 14.17 6.10 13.91 15.58 15.46 16.44 14.87 13.20 12.04 9.83 6.60 15.99 16.74 16.90 16.46 14.02 17.63 12.62 13.17 18.78 13.73 11.82 18.04 17.76 17.28 17.62 10.14 12.47 13.62 14.11 8.73 14.08 11.10 17.35 15.10 8.77 11.80 15.79 16.11 9.80 12.30 12.84 15.20 14.92 10.28 16.85 16.33 17.63 14.97 15.93 17.75 10.41 11.42 11.49 10.46 16.62 16.71 11.59 15.18 15.59 16.59
SGSVIDQSRVLNLGPITR 22.78 18.08 21.66 16.50 16.43 15.80 19.18 14.75 19.64 21.29 23.03 20.30 18.34 19.12 24.35 23.18 10.05 10.45 17.54 18.93 20.45 21.13 21.56 14.23 9.92 15.42 19.55 14.69 18.23 18.81 20.18 20.80 19.02 16.85 11.75 12.03 12.19 21.30 20.50 20.49 20.07 15.00 17.38 11.93 17.24 22.93 18.40 17.43 23.25 22.43 22.72 22.35 24.02 22.87 24.35 20.74 21.86 21.43 22.30 24.55 15.39 13.03 16.81 17.95 21.98 15.18 16.93 12.82 17.05 20.90 15.86 19.74 21.26 19.90 18.78 19.79 19.34 17.98 14.18 15.02 16.61 20.77 20.40 16.65 20.05 20.11 19.32
FQTPSYTQPYQGSSVTL 16.18 14.28 17.24 12.11 11.71 12.67 11.79 10.27 13.10 13.78 15.25 16.17 11.84 12.34 15.16 13.10 10.45 10.93 14.46 13.42 13.85 14.11 13.96 11.77 11.30 13.41 13.42 9.50 13.14 14.94 12.33 13.81 13.04 12.55 10.61 12.73 11.77 10.42 11.44 11.84 11.95 13.25 16.25 10.48 11.13 16.08 10.13 14.90 14.69 18.83 12.80 14.45 12.86 13.21 14.66 12.59 13.41 16.08 16.93 18.65 14.32 9.89 11.12 15.44 13.26 9.89 8.51 11.94 15.25 10.16 10.38 12.32 10.66 13.54 13.88 13.50 14.93 12.25 13.00 9.02 10.60 12.00 11.78 7.93 13.48 15.20 10.18
DDQSAETHSHKQSRLY 20.46 15.35 16.42 15.83 16.68 17.09 17.66 12.36 15.94 15.39 18.55 14.85 14.31 15.85 17.52 17.30 12.88 9.12 17.12 14.35 16.87 19.09 16.62 16.19 14.23 8.86 15.18 14.50 16.91 17.76 17.62 18.85 17.94 16.46 12.94 13.76 13.01 17.82 18.00 18.38 18.95 15.09 19.50 14.13 16.43 20.82 16.41 15.89 18.64 17.78 18.10 16.50 18.08 17.82 18.16 14.42 15.54 16.64 15.76 18.00 17.48 14.80 15.69 13.03 18.67 16.88 16.28 14.42 18.68 16.27 14.99 17.78 19.12 19.96 19.12 19.23 19.50 15.90 15.68 14.95 15.59 19.15 18.64 14.90 17.25 19.92 17.12
LSRQELFPFGPGQGDLE 16.91 10.54 14.67 13.27 9.67 8.50 13.10 10.50 13.18 13.07 15.64 11.91 12.09 11.90 14.73 14.40 9.87 10.17 13.78 12.03 12.00 11.89 11.58 11.83 9.38 13.42 10.97 7.78 10.84 11.41 11.86 14.11 12.52 11.28 9.79 10.59 10.98 12.55 12.09 13.67 10.75 12.62 12.87 10.36 12.38 16.58 11.88 12.94 15.11 16.72 14.28 14.89 15.58 15.28 15.45 12.80 12.06 13.74 11.68 15.46 12.09 10.29 8.55 12.06 12.47 8.49 9.76 10.02 13.30 11.33 10.37 13.64 12.34 12.12 12.26 13.47 14.26 11.16 9.07 8.18 11.49 12.16 13.13 8.34 11.29 12.92 11.63
DEAGSEADHEGTHSTKRG 23.55 21.65 21.13 21.42 20.89 20.54 21.59 19.63 20.42 21.21 24.06 21.58 20.81 21.71 23.65 23.57 19.94 7.98 18.81 21.63 12.95 12.40 18.94 15.98 16.87 14.06 13.34 11.23 18.59 19.93 18.21 8.57 19.69 18.65 9.85 11.33 17.65 16.04 13.50 19.91 17.63 19.47 20.10 10.38 20.67 22.89 21.29 21.80 23.83 23.46 23.46 21.80 22.33 22.42 23.25 21.41 21.60 22.35 20.72 22.00 14.53 16.08 14.58 13.58 18.83 12.91 20.04 16.91 11.88 11.51 17.17 13.58 16.56 16.03 17.91 18.73 19.23 18.32 15.01 9.14 11.89 20.54 19.48 13.74 15.68 17.03 15.15
TTTPSKQSNNKYAASSY 17.92 17.09 15.71 16.89 15.49 16.23 17.57 12.70 17.52 15.15 17.43 16.32 15.43 16.65 16.08 15.23 13.04 10.73 15.52 14.43 13.69 12.82 14.36 14.12 14.11 14.27 13.71 13.19 15.16 14.26 17.23 18.11 15.88 15.91 10.81 10.39 13.29 15.00 13.89 15.05 14.35 15.41 18.05 12.40 13.38 18.49 16.37 16.52 17.40 19.16 16.89 16.26 16.77 13.56 15.43 15.12 15.97 17.28 14.81 16.43 15.15 12.52 13.32 14.48 12.94 14.21 15.23 12.67 16.08 13.74 12.81 16.80 15.73 14.74 16.59 14.90 16.57 13.57 12.99 14.72 14.27 13.54 15.83 14.23 14.76 14.03 14.96
LWVGTGASEAEKTGAQEL 12.89 9.69 16.07 11.01 10.71 11.47 13.24 10.70 8.70 13.19 15.24 11.92 13.06 12.20 14.79 13.60 10.76 5.27 12.83 10.58 10.26 13.26 12.20 10.52 9.86 11.45 6.65 11.95 12.66 10.45 14.33 14.75 13.58 11.17 12.08 11.51 12.89 12.16 11.29 12.22 12.85 10.16 14.81 11.89 11.62 15.14 10.13 12.73 14.66 9.52 12.93 10.25 13.83 10.76 13.61 12.35 13.23 13.38 12.75 13.23 12.49 7.77 11.91 14.12 13.22 11.62 8.60 11.50 12.87 8.57 11.49 13.89 10.50 12.68 11.28 13.50 10.96 9.64 10.41 12.24 9.74 12.48 11.70 9.15 11.97 12.53 11.00
VSWVPPPAENHNGIIRG 17.70 14.39 15.58 12.91 13.35 11.74 13.91 10.63 15.30 14.44 15.81 14.83 13.42 12.83 15.05 17.12 10.48 10.15 13.75 11.67 14.05 13.40 13.07 11.61 12.62 13.02 14.50 13.28 13.84 14.15 13.08 15.83 14.48 11.80 13.52 10.96 13.10 14.95 13.10 15.77 14.09 13.47 16.99 12.70 12.38 18.68 11.88 14.10 17.27 17.77 15.86 16.47 17.54 17.49 16.21 14.97 15.08 15.54 14.79 17.08 12.70 12.40 11.54 12.85 13.10 11.54 15.32 10.17 14.58 13.67 14.08 16.55 15.79 17.59 14.90 16.63 17.32 13.56 14.33 13.11 13.24 15.80 15.74 12.40 13.14 15.26 15.41
FRVVAQGVGIPEDSIFT 16.30 13.98 16.33 13.83 14.50 13.73 14.44 9.74 12.52 12.62 19.91 12.48 13.90 11.02 16.02 14.22 12.13 12.00 14.24 11.44 11.40 11.88 13.08 7.89 12.70 8.11 11.82 13.26 13.35 10.88 15.00 14.86 14.24 13.41 13.42 11.79 13.83 13.95 13.93 13.98 9.90 13.62 15.07 12.65 13.41 17.81 12.46 13.96 16.29 16.92 15.61 15.00 15.80 16.63 16.92 14.24 12.36 15.56 14.39 16.94 9.25 13.08 12.20 12.28 16.99 13.60 6.56 12.90 13.81 12.32 11.71 15.05 12.70 12.69 10.95 11.68 12.78 12.53 14.33 12.39 12.69 13.26 13.36 12.99 12.16 12.17 11.37
LQDFRVVAQGVGIPEDS 14.81 10.43 15.48 10.89 7.57 11.01 8.36 8.70 13.89 13.78 17.12 16.17 10.19 12.49 14.67 13.04 10.97 9.18 15.38 9.89 13.35 13.80 8.04 11.07 10.61 10.84 12.92 12.28 12.62 11.13 12.90 12.22 12.53 12.78 11.16 11.70 11.35 9.91 11.61 13.11 13.04 11.27 15.42 7.36 7.76 15.10 16.23 11.11 13.32 16.40 14.45 14.88 13.88 13.69 14.91 13.17 11.80 15.31 16.93 15.27 12.68 6.93 12.89 14.32 12.82 11.92 13.62 10.93 13.33 13.45 12.43 13.22 13.29 11.46 9.10 13.50 11.39 11.98 11.33 12.93 8.19 10.31 12.85 12.20 10.86 13.83 9.08
TGYQVDKNKDDELTGF 14.54 16.10 18.07 15.20 14.77 13.75 14.82 11.53 17.21 13.59 15.20 11.42 14.54 15.09 14.16 13.02 12.29 12.79 15.65 13.64 14.18 12.58 13.76 14.18 14.85 14.68 12.26 13.87 15.90 14.72 15.83 16.60 15.39 14.25 14.97 15.13 14.36 14.26 15.06 13.69 13.30 15.41 16.80 14.39 14.36 16.20 13.67 14.42 14.48 17.03 14.36 12.14 18.44 11.46 14.35 14.92 15.77 14.36 14.24 14.89 15.67 15.35 13.79 14.39 8.00 16.76 15.16 14.47 15.34 12.63 13.88 14.53 14.73 13.90 17.61 10.97 15.95 14.22 16.27 15.94 15.06 12.29 13.22 14.30 14.25 15.14 12.16
DEAGSEADHEGTHSTKR 20.28 18.73 16.92 16.73 17.97 12.49 18.75 16.81 15.28 17.03 20.92 17.83 18.04 17.98 20.53 20.49 17.07 12.17 18.38 18.44 11.49 12.81 12.52 12.37 12.71 13.42 12.53 12.59 13.47 15.61 13.62 15.94 15.66 14.08 12.44 11.57 12.42 12.12 13.04 12.72 12.69 13.75 15.14 12.48 16.89 19.97 16.53 17.45 20.63 19.28 20.47 18.12 19.52 18.01 20.18 18.39 18.70 18.88 17.84 17.79 13.32 7.33 11.51 14.80 16.99 13.16 17.34 12.60 9.24 12.50 13.32 13.58 12.85 11.84 13.28 17.13 14.80 12.50 14.03 12.39 12.75 13.05 14.58 12.38 7.78 14.58 12.67
VSEDPINDGEWHRVTA 19.94 15.77 18.31 15.50 13.12 12.84 15.55 14.00 15.50 14.97 19.19 14.18 15.12 16.30 17.21 18.43 11.28 6.37 17.49 17.39 16.97 16.61 16.11 15.13 15.62 15.03 11.89 12.59 17.78 19.06 20.76 21.96 20.72 19.03 13.50 14.04 14.11 19.70 19.07 19.49 18.29 17.68 20.97 13.23 15.06 21.78 15.40 15.80 19.25 20.86 18.62 14.64 16.63 17.74 17.75 14.14 16.05 16.37 15.55 18.98 18.05 13.29 13.21 15.97 11.92 12.84 14.60 14.07 19.01 17.59 16.13 19.99 17.57 18.00 18.22 14.51 20.50 15.50 17.85 15.65 17.56 17.56 18.93 16.24 17.27 18.75 18.77
Q(-17.03)GQYDLDPLPPFPDHV 14.03 10.98 14.95 11.24 9.84 9.86 13.23 10.99 13.76 14.80 12.39 13.68 12.13 11.94 14.05 10.36 11.25 10.51 14.93 13.92 13.69 14.38 13.32 13.96 12.03 14.92 14.35 13.54 13.61 13.75 13.27 14.20 12.92 12.00 9.14 11.02 9.95 13.05 14.35 13.04 13.57 12.42 15.56 10.69 12.18 14.35 13.34 12.73 14.73 15.30 13.96 13.00 13.85 13.78 13.54 12.26 13.49 13.97 14.33 12.85 14.33 12.81 14.68 14.64 10.90 14.53 15.03 12.07 14.89 12.89 14.02 13.78 11.98 10.82 12.85 11.26 12.99 11.95 11.70 12.01 13.00 11.97 13.50 12.38 11.88 13.99 13.39
DHDVGSELPPEGVLGALL 14.98 14.29 14.23 13.42 13.54 12.26 12.92 12.28 13.63 13.35 15.64 12.58 11.55 12.69 15.63 14.51 9.22 12.40 12.93 16.34 16.31 16.84 14.71 13.65 10.78 13.15 15.16 11.93 13.87 14.23 15.95 15.64 15.10 12.88 12.62 11.08 12.66 13.63 15.02 13.79 11.27 8.67 16.32 11.97 13.21 14.45 16.23 14.51 14.37 15.76 15.72 12.55 14.70 13.21 13.07 12.33 13.72 11.63 14.69 13.80 13.55 12.59 14.90 13.04 14.34 13.21 14.88 11.60 10.82 16.29 14.80 15.11 13.57 12.62 14.89 11.65 14.71 12.48 14.78 13.90 10.40 12.28 14.17 11.93 13.05 14.98 13.29
LREGRRGSIQVDGEEL 19.35 14.17 17.66 13.92 12.19 13.67 14.93 13.04 15.72 15.43 19.02 14.46 12.81 14.58 15.58 14.71 12.23 10.62 14.13 14.77 14.21 14.84 13.07 12.01 12.34 14.42 14.29 13.36 14.12 15.00 16.60 17.24 16.82 15.09 13.40 12.70 13.04 15.47 15.36 17.12 14.18 12.63 17.53 12.78 13.49 21.06 12.42 13.30 19.22 20.10 18.03 16.07 16.31 19.03 14.94 14.85 14.64 15.26 14.81 14.84 14.03 12.47 13.77 13.73 13.86 13.73 15.43 12.50 14.75 13.36 13.82 18.05 15.61 16.43 15.19 11.26 17.18 13.59 12.98 13.21 13.28 15.66 14.43 14.05 11.77 13.59 14.24
DVQNVAAAPELAMGALEL 12.16 13.17 12.55 12.20 9.84 11.67 12.67 11.31 12.77 14.10 14.88 12.06 13.13 12.71 14.23 12.74 11.25 11.01 12.67 13.04 12.63 13.80 13.49 13.34 11.08 14.46 12.24 11.17 10.79 11.37 13.38 12.15 12.05 11.40 12.12 12.12 12.44 12.34 12.68 12.99 13.30 10.96 15.42 11.92 12.17 14.04 10.34 9.11 14.17 14.50 14.41 12.24 13.07 14.02 14.13 12.76 13.18 14.29 14.05 13.12 14.32 9.48 12.32 14.23 9.83 12.07 10.99 12.30 13.69 11.94 13.09 13.62 12.98 12.96 13.44 11.26 8.37 8.89 13.78 11.05 10.02 8.69 12.06 10.43 12.73 13.49 12.52
VDALHEIPVKKGEGAEL 15.74 11.84 19.12 13.42 11.42 12.24 14.39 10.17 15.36 12.84 15.81 12.97 10.82 12.10 14.63 13.74 11.16 9.96 12.90 13.49 11.37 10.88 12.29 11.67 10.28 12.87 11.49 12.05 13.42 14.60 10.77 14.09 12.04 11.36 10.43 12.24 10.98 12.26 15.46 14.10 14.46 13.01 14.97 10.92 12.27 16.93 12.64 11.87 14.40 16.01 14.57 14.46 15.87 13.78 15.02 14.37 13.16 14.94 14.19 14.36 11.87 9.86 10.31 16.30 12.43 12.86 13.08 8.99 13.79 12.49 13.05 15.21 12.74 11.76 12.85 14.31 14.85 11.65 13.58 12.18 10.45 13.43 14.18 10.58 13.89 15.73 14.52
EEAPSLRPAPPPISGGGY 14.89 13.28 16.02 14.97 10.06 12.53 14.72 10.14 12.75 13.09 15.82 12.65 10.70 14.22 14.26 13.92 10.75 10.80 12.40 14.77 11.50 12.40 12.81 12.35 11.86 14.34 12.48 13.67 11.39 12.43 12.98 13.27 13.31 11.99 9.60 11.45 10.57 12.29 13.38 13.16 13.48 12.70 13.85 12.43 12.81 16.12 12.64 14.26 14.58 15.49 14.52 15.08 16.31 13.68 14.71 12.71 13.36 14.18 15.15 14.40 13.96 11.61 13.17 14.28 12.52 14.01 15.69 11.67 13.82 13.51 15.49 14.17 12.60 10.43 12.00 13.47 14.24 12.00 13.08 12.31 12.71 12.53 13.30 9.28 12.69 14.49 13.63
S(+42.01)SYQQKQTFTPPPQL 13.79 14.72 16.00 13.05 10.83 10.71 13.01 8.01 16.04 10.30 14.49 11.28 12.92 9.03 14.62 13.96 10.69 11.85 11.26 10.16 13.55 13.90 12.61 10.39 9.38 11.00 12.94 10.33 11.31 12.72 12.45 10.55 11.23 12.13 11.50 11.48 8.78 10.60 9.26 13.67 9.70 12.21 12.58 12.39 14.72 10.59 11.71 10.10 15.24 10.31 13.44 8.26 15.86 15.35 14.44 12.90 14.87 13.42 16.30 13.23 11.34 11.84 10.60 13.52 11.34 11.50 10.95 11.75 12.92 12.90 9.40 12.86 13.44 12.18 11.99 11.26 11.91 10.48 11.73 11.96 9.40 12.61 14.11 10.61 10.88 10.57 11.72
YKAIPVAQDLNAPSDW 16.78 12.37 17.25 11.73 10.26 12.43 15.65 10.19 9.92 13.20 14.90 13.75 13.71 12.69 14.38 14.11 9.87 10.17 13.38 12.05 11.76 11.91 13.01 11.73 7.35 13.17 11.10 10.06 11.50 10.95 13.92 12.77 10.53 10.58 9.54 10.59 10.98 14.64 13.43 12.92 13.30 11.90 14.42 10.36 11.75 16.60 11.88 12.60 14.86 16.30 13.44 15.79 16.31 14.35 14.01 14.75 13.05 13.41 15.15 14.51 12.07 9.57 11.73 15.67 12.43 12.37 13.53 10.94 13.65 12.06 10.78 12.03 12.87 11.72 13.87 13.45 14.62 10.58 9.67 11.61 11.67 12.21 13.54 8.88 13.38 15.66 9.35
EVDETYVPKEFNAET 16.95 15.38 17.66 13.99 13.38 11.37 13.00 10.66 14.23 7.04 12.09 12.16 12.93 10.71 15.48 13.82 10.51 10.75 14.71 12.22 12.38 13.10 11.85 11.36 11.23 8.25 8.04 6.34 12.09 14.16 15.29 14.98 15.10 12.67 13.32 12.56 12.96 12.67 14.53 14.52 9.68 11.08 14.04 14.54 8.11 16.17 11.34 12.10 15.63 9.62 14.40 14.18 14.81 14.82 13.19 13.89 15.43 15.56 13.21 15.41 12.89 10.85 11.97 15.59 11.12 12.16 12.23 9.29 13.20 11.02 12.22 14.46 13.13 14.32 13.63 12.48 14.29 11.36 14.84 13.72 12.34 14.06 15.18 10.36 13.75 15.19 13.20
EVQVFAPANALPARSEA 13.82 15.40 15.38 15.89 13.96 14.25 16.19 12.80 15.64 15.20 14.08 15.55 13.61 14.59 12.41 11.12 12.36 13.13 14.29 12.91 11.98 11.07 12.02 14.36 13.18 14.42 11.87 13.52 13.30 13.50 16.27 14.37 13.51 13.95 10.26 11.25 12.69 14.70 12.79 11.83 14.45 13.01 13.08 11.31 14.06 14.09 14.85 13.92 12.63 14.47 13.10 12.90 13.72 14.08 12.95 14.13 15.47 14.30 15.24 13.50 14.85 14.06 14.73 11.55 11.99 14.51 14.44 13.25 13.01 12.41 14.01 12.32 13.36 12.44 14.28 9.12 13.45 14.46 13.31 13.62 14.30 11.27 12.55 13.39 13.72 13.13 12.34
SVIDQSRVLNLGPITR 20.20 14.84 17.19 14.01 13.89 12.93 12.83 10.14 14.83 17.18 19.49 14.74 9.88 15.08 20.61 18.85 11.85 12.14 14.09 17.15 16.74 18.14 18.02 9.50 13.21 8.84 15.89 8.02 12.55 13.79 15.39 15.82 16.39 10.27 13.44 11.90 13.17 16.76 16.42 15.31 15.05 13.99 15.27 13.01 8.58 18.52 12.35 12.91 20.03 17.86 17.80 17.59 18.41 21.10 20.94 15.36 16.91 17.64 18.57 19.18 13.51 13.39 11.97 15.14 17.56 9.45 12.47 12.80 11.57 16.46 10.89 15.71 16.50 15.93 13.90 16.64 14.85 12.40 14.61 12.57 12.64 16.59 15.82 11.74 14.21 15.34 15.34
SGSVIDQSRVLNLGPIT 19.17 15.67 19.48 15.75 12.91 14.66 18.33 13.22 18.19 19.20 17.29 17.68 16.33 18.92 19.93 18.11 13.05 12.29 18.83 18.09 19.47 19.21 16.31 16.47 15.98 18.29 18.92 16.90 11.47 15.50 12.84 13.93 15.57 12.28 10.93 11.65 12.01 14.62 12.18 15.10 16.21 13.92 17.13 12.60 15.40 19.36 18.43 16.35 20.44 19.38 19.77 16.68 17.31 18.69 17.28 17.89 18.14 19.76 18.28 20.13 18.45 15.43 18.79 17.29 14.24 17.96 19.63 15.35 19.35 16.58 16.78 11.58 14.86 14.52 15.05 11.04 16.52 11.67 14.06 15.37 15.09 16.50 15.27 13.87 12.18 14.73 16.28
YADKPETTKEQLGEF 17.62 15.38 17.30 15.01 16.63 14.68 15.48 12.37 15.81 12.42 17.04 15.96 15.50 15.84 15.92 15.18 11.70 10.56 15.77 12.88 12.77 10.32 11.60 14.66 14.11 14.18 9.36 11.47 15.57 15.39 20.01 18.99 18.68 15.40 16.84 13.56 16.29 15.36 14.71 15.77 11.93 15.35 20.29 14.60 12.33 16.50 13.24 15.74 10.37 19.40 13.52 13.38 18.72 13.11 15.71 16.20 14.23 16.09 14.01 16.47 15.45 13.57 12.61 14.67 7.73 14.09 15.33 13.99 15.70 14.99 14.01 16.51 16.48 10.84 18.09 12.89 16.87 15.38 16.95 17.06 13.24 13.78 15.55 11.85 15.32 17.91 14.00
VVENGESSQGRFSVQM 13.24 14.68 15.62 12.37 12.66 11.38 14.50 11.46 14.10 13.25 14.40 12.63 11.60 12.55 14.72 11.88 8.74 10.80 12.60 13.47 12.86 13.47 13.16 11.41 10.70 12.34 10.71 8.53 13.93 15.71 15.01 14.95 14.43 14.04 12.67 11.95 14.07 12.61 13.91 13.93 12.81 13.47 16.63 11.64 12.67 14.22 16.23 13.83 12.91 15.35 12.44 13.68 16.21 13.48 13.05 12.37 13.01 14.12 16.16 14.09 12.68 12.13 11.51 12.45 12.82 12.11 9.49 11.90 13.26 12.02 9.72 13.27 12.88 11.88 13.72 11.26 14.13 12.44 14.99 13.34 13.66 12.51 13.64 11.59 13.18 15.16 12.99
VVSLGSPSGEVSHPRKT 17.01 14.47 16.41 12.64 15.38 13.28 12.15 7.84 13.76 13.60 17.45 13.84 12.53 12.77 12.92 13.92 10.98 12.74 13.90 12.15 15.73 15.25 11.14 12.03 13.12 13.97 14.49 9.19 14.56 13.79 15.94 20.17 17.28 16.35 12.92 13.56 12.50 14.33 15.47 12.44 12.04 13.00 16.10 13.64 12.93 17.82 13.22 11.93 16.83 14.89 16.90 13.37 15.56 15.91 13.07 13.93 14.38 13.42 13.85 16.96 13.71 13.16 9.18 14.24 13.70 13.42 14.70 12.32 14.23 15.71 14.37 16.70 13.75 16.10 13.09 13.92 16.45 12.11 14.47 13.81 11.47 13.04 14.31 13.65 14.51 15.03 15.31
IPGGLSEAKPATPEIQE 13.38 15.12 16.66 13.39 14.03 11.27 12.33 11.22 15.36 12.87 10.52 14.72 12.86 12.66 15.16 13.53 10.24 12.27 9.79 13.53 13.64 14.07 12.63 11.86 12.83 11.01 12.94 11.31 13.56 11.69 13.27 11.98 11.01 9.69 12.33 10.95 10.44 11.26 13.54 11.77 12.85 12.57 13.22 12.30 13.94 14.15 11.13 11.66 14.94 12.71 12.80 13.41 13.06 13.69 13.85 13.67 15.53 13.39 16.93 12.66 11.54 11.38 10.72 13.52 12.82 12.72 10.75 11.92 13.09 13.09 10.07 12.64 13.54 11.71 15.80 13.50 12.63 11.86 12.47 13.52 11.45 12.87 14.00 11.57 11.21 13.02 11.00
FRVVAQGVGIPEDSIF 18.24 14.32 17.80 12.39 11.03 11.40 14.25 9.86 15.31 13.70 21.48 15.82 13.77 14.40 16.99 16.21 11.96 11.49 16.80 13.33 13.23 13.08 14.59 12.08 8.25 12.19 12.52 13.36 10.45 14.11 17.24 17.36 16.30 12.56 11.91 12.93 11.69 16.04 15.91 15.88 12.02 13.44 16.27 12.24 12.94 19.35 12.46 10.85 17.62 19.06 16.56 16.96 18.45 18.45 18.60 15.33 15.21 17.34 17.26 18.48 11.63 13.07 10.11 14.66 9.12 8.02 11.26 12.70 15.94 13.97 14.44 17.55 15.15 14.73 14.88 15.45 16.26 12.14 5.88 12.04 12.79 16.08 15.89 11.58 14.82 15.40 14.14
VDISQDNALRDEMRA 16.63 15.83 16.32 15.20 13.49 13.52 15.06 12.36 15.87 14.08 16.80 15.33 14.52 15.26 14.80 13.97 11.87 8.07 14.12 13.77 12.91 13.64 13.19 14.97 15.14 15.39 15.27 11.69 15.59 16.41 17.74 17.73 17.26 15.23 13.56 10.92 13.61 15.76 15.72 15.62 13.76 15.84 17.59 13.66 12.00 17.44 16.23 15.50 15.52 19.18 15.23 15.07 17.07 14.85 15.86 14.44 14.78 16.35 14.69 15.03 16.11 13.90 13.37 14.34 10.97 12.43 13.35 14.34 17.44 14.03 14.49 17.40 15.19 15.09 16.29 14.47 16.79 13.14 16.11 14.44 14.90 13.57 16.56 13.48 13.69 16.09 14.87
SEDPINDGEWHRVTA 15.57 9.40 16.76 10.16 13.48 12.41 12.51 14.43 13.32 7.04 14.58 10.57 10.26 12.56 15.48 13.33 9.26 11.70 12.72 13.87 13.03 11.18 12.77 10.47 11.30 12.93 8.61 7.25 12.71 14.63 15.90 16.98 15.82 14.49 6.55 13.48 10.23 14.65 14.42 14.91 13.82 13.63 16.29 12.86 9.55 17.08 11.34 13.37 13.22 15.79 13.78 11.37 14.10 12.89 10.91 13.75 9.84 14.74 12.03 15.60 13.70 12.11 11.66 14.06 13.10 12.09 9.71 11.89 13.82 8.58 12.63 13.71 12.67 14.44 13.97 12.22 15.95 12.23 13.04 11.18 12.53 13.28 15.06 11.39 12.74 14.02 14.08
LWQGVEVGEAGQGKDF 15.98 13.72 17.11 13.36 13.38 11.38 14.12 9.44 12.02 13.58 15.63 12.21 13.78 13.17 14.73 14.57 11.75 11.34 14.91 13.56 12.18 12.42 12.31 11.92 11.27 12.18 12.07 13.08 13.01 14.84 15.37 16.62 16.17 14.13 11.59 8.19 12.65 14.65 14.57 15.08 13.65 12.65 12.91 8.61 12.72 17.81 12.24 7.05 16.20 16.59 15.40 17.43 13.94 12.90 15.03 13.10 13.86 14.90 12.65 14.82 14.72 9.82 12.31 15.04 13.26 13.16 14.02 12.52 15.33 12.02 12.50 14.40 10.94 13.40 13.05 11.26 15.10 10.65 12.43 12.16 12.90 13.33 14.96 11.17 12.85 13.93 14.18
IPVKQADSGSSEEKQL 16.95 14.22 14.35 13.19 13.96 14.09 13.03 13.40 14.11 12.71 12.13 12.86 13.85 13.47 15.13 14.36 10.08 12.77 13.79 14.09 13.04 13.89 12.99 13.52 13.89 12.98 10.80 11.77 12.70 14.51 14.72 14.24 13.17 11.86 13.09 13.58 13.39 12.94 13.69 13.89 15.13 13.64 17.71 12.01 14.08 16.68 10.94 14.58 14.70 15.85 15.00 14.72 14.63 12.62 14.77 14.02 14.58 15.11 13.50 14.93 14.07 14.04 11.49 11.41 11.72 13.16 14.44 12.97 15.39 11.03 12.62 14.77 13.45 14.06 17.25 14.07 16.16 12.33 15.60 14.86 12.36 13.27 15.03 12.50 15.13 16.80 13.02
VQVFAPANALPARSEAA 14.29 16.06 14.82 15.33 14.18 14.94 15.15 13.52 15.19 14.91 13.18 14.36 15.31 14.83 14.62 12.53 13.77 14.93 15.43 14.04 11.80 11.23 12.94 14.53 14.79 16.00 12.50 13.67 14.94 14.61 13.69 13.31 12.98 12.09 12.86 12.58 12.72 12.46 13.84 12.83 14.22 14.16 14.68 12.81 14.93 15.59 14.36 16.20 14.06 15.83 13.39 13.96 15.63 15.64 14.73 15.69 15.95 16.81 16.08 14.83 15.10 15.64 13.57 14.37 8.40 13.90 12.93 15.20 15.34 10.98 12.94 13.96 13.43 12.55 14.72 10.80 14.87 13.24 14.64 13.06 13.55 13.57 13.84 12.49 13.81 15.57 12.85
DHDVGSELPPEGVLGAL 15.72 14.47 17.77 14.40 13.65 13.06 17.13 9.78 16.59 14.22 18.21 15.48 15.21 16.41 18.28 16.25 12.79 13.12 16.91 18.15 18.12 18.49 16.93 16.98 14.90 16.69 16.93 14.95 15.87 14.78 17.53 16.02 16.69 16.30 12.23 12.85 12.39 16.96 15.84 15.83 15.91 14.82 13.32 13.39 12.57 16.26 15.20 13.52 17.48 16.28 18.32 14.68 15.80 16.32 17.19 15.57 16.77 16.58 16.04 17.47 17.50 13.77 17.36 16.82 15.04 15.44 16.49 15.00 15.61 17.26 17.10 13.30 15.65 9.10 14.36 12.51 13.98 15.75 14.01 17.43 15.71 14.34 15.04 15.74 15.30 11.59 16.29
SQDASDGLQRLHMLQ 19.11 15.40 17.62 14.83 12.60 10.51 15.59 7.21 15.70 14.29 17.58 13.98 15.81 14.83 17.80 15.49 13.46 8.86 16.56 16.28 17.23 16.94 15.70 14.30 14.39 15.81 12.72 12.06 16.38 16.68 15.77 16.66 17.08 15.15 13.05 13.31 11.60 15.77 16.97 15.72 17.26 15.72 17.77 11.40 11.43 19.19 17.13 14.80 18.64 18.95 17.43 16.36 18.83 16.91 18.18 15.35 15.97 17.19 15.10 15.03 16.26 13.26 13.35 16.66 13.44 14.17 13.23 14.90 18.44 14.89 12.68 16.99 16.79 17.18 17.25 15.35 18.11 12.08 17.34 15.01 14.63 16.21 17.49 12.22 14.60 17.69 16.61
YRITEATKTVGSDTF 18.33 13.45 14.29 9.69 7.80 13.34 14.27 13.04 15.98 14.10 17.53 13.55 13.70 13.35 17.75 15.50 10.33 9.78 15.22 14.59 14.16 14.73 13.41 11.46 13.05 13.26 14.67 12.86 14.20 15.97 15.37 16.46 15.57 14.00 13.70 10.75 11.77 14.79 16.12 16.42 16.08 15.35 15.70 12.64 13.88 19.22 11.82 13.56 17.85 18.43 16.85 16.73 19.15 15.76 17.43 14.95 13.13 16.88 14.29 17.35 14.64 10.75 13.79 14.76 13.76 13.95 15.17 13.23 16.83 13.71 11.72 16.82 16.53 16.23 16.51 14.27 17.55 14.26 15.01 13.41 12.40 16.22 17.68 14.97 16.31 17.69 16.40
NKEIPAWVPFDPAAQ 19.96 12.41 15.69 13.35 14.19 10.00 14.04 12.79 13.68 13.42 15.93 15.30 13.01 13.90 15.98 13.44 7.26 12.51 14.68 12.09 11.22 11.03 11.26 12.89 10.84 10.78 13.88 10.97 11.71 13.38 18.13 19.96 16.83 12.59 10.77 12.08 11.47 14.53 14.35 15.94 12.36 14.01 19.12 9.69 9.35 17.88 12.76 13.27 17.06 18.44 14.29 15.74 16.61 16.51 14.71 13.71 13.91 13.97 15.83 15.69 14.22 12.68 7.83 12.79 13.31 10.06 10.63 10.57 14.88 11.27 10.01 18.09 16.13 15.36 15.68 14.73 18.16 10.48 13.01 13.21 8.21 14.78 14.58 11.70 14.62 16.41 13.78
VIDQSRVLNLGPITR 18.18 14.02 18.35 12.76 12.32 12.98 10.58 10.43 15.31 16.76 20.87 13.24 12.15 12.57 20.00 17.26 10.69 11.79 13.71 16.34 16.27 17.03 18.89 12.08 12.70 13.05 16.00 10.45 14.70 13.83 18.05 13.30 15.28 13.17 11.77 12.96 11.41 17.92 18.47 16.48 14.13 14.15 17.19 12.33 14.06 18.03 11.71 13.33 17.75 19.23 16.81 19.13 20.21 18.92 21.65 14.97 15.01 16.21 15.96 20.17 13.63 12.42 14.58 14.16 19.56 12.19 12.09 12.20 14.59 18.28 13.04 19.19 17.23 15.14 13.12 15.25 12.93 14.10 14.50 13.48 12.86 16.74 13.81 10.70 17.12 15.33 15.61
DEAGSEADHEGTHSTK 16.62 15.88 16.20 16.63 13.40 13.39 15.73 13.56 14.50 16.01 18.23 15.20 14.59 16.47 17.53 11.37 14.07 9.08 16.04 13.11 12.93 12.84 11.32 11.96 12.62 13.19 13.94 10.95 13.80 13.54 14.42 13.72 12.91 12.69 13.70 13.02 13.65 12.55 13.44 13.56 14.23 13.59 15.97 13.30 13.39 16.52 17.09 16.75 17.59 14.98 16.04 13.71 15.14 11.02 15.30 16.79 16.15 17.25 14.81 15.60 14.09 12.94 13.51 14.15 13.86 11.47 13.92 12.77 13.95 12.43 13.34 13.55 13.69 13.62 14.59 17.13 11.97 12.42 14.73 13.13 13.06 13.47 13.77 13.49 11.67 11.38 13.96
DAPGQYGAYFHDDGF 19.04 16.40 18.32 17.03 15.18 14.01 16.70 12.15 16.83 15.21 19.46 15.54 16.22 17.85 18.02 18.74 10.26 11.68 18.53 18.96 18.37 18.41 17.22 16.57 16.93 15.82 13.36 14.44 17.03 18.50 19.09 19.57 19.38 18.75 13.29 11.39 12.62 18.59 17.96 17.56 17.15 16.51 16.18 13.96 14.18 20.94 13.80 15.79 19.35 19.55 19.13 15.41 17.42 17.23 18.57 15.53 17.35 18.19 16.17 18.35 18.24 13.84 16.05 17.52 13.80 14.68 17.71 15.14 18.48 17.91 17.30 18.09 15.82 16.40 16.57 12.81 18.67 15.72 16.81 16.24 17.12 16.78 18.07 15.62 16.48 16.00 17.37
SGSVIDQSRVLNLGPI 20.15 13.43 19.44 12.54 13.26 12.98 14.91 10.03 16.39 17.41 17.46 14.49 13.29 18.22 20.05 16.35 11.76 11.97 17.79 17.66 19.34 19.55 16.46 13.47 11.16 15.97 17.50 15.06 10.36 13.64 12.75 14.70 15.57 13.90 13.07 10.47 13.40 14.57 13.33 14.09 13.03 13.76 13.69 12.90 11.83 19.38 15.62 15.65 19.92 18.95 17.36 15.47 9.48 20.77 17.68 15.57 14.41 18.27 16.93 20.08 16.20 13.98 18.65 15.35 12.71 13.75 18.42 12.67 17.68 16.27 15.59 11.84 13.41 14.25 13.06 17.13 15.20 10.42 14.24 13.90 10.67 17.22 13.05 12.09 11.57 14.56 15.88
VKVWPQQPSGELFE 17.11 14.12 17.73 13.58 12.22 13.46 14.39 10.22 13.47 11.61 15.97 14.19 12.38 11.96 13.35 12.38 12.04 11.79 13.52 10.87 12.24 15.48 9.64 7.37 9.23 13.84 14.41 12.41 14.80 15.31 15.16 18.80 17.42 13.75 12.16 13.34 12.27 12.01 11.88 12.96 12.75 11.60 14.51 13.09 10.54 18.46 13.22 12.88 16.89 16.33 16.18 12.67 15.06 11.00 14.02 12.45 14.23 14.42 14.26 16.13 12.64 12.00 14.48 15.38 14.54 9.07 11.33 12.26 14.42 11.71 11.68 15.00 12.68 13.68 11.73 14.94 16.05 13.07 10.58 5.84 11.28 13.87 15.74 13.77 10.98 13.79 12.99
VQVFAPANALPARSEA 15.83 17.34 15.54 17.27 16.06 16.62 17.53 15.31 16.95 16.62 15.33 16.40 16.46 16.45 14.96 14.25 15.86 15.90 16.76 15.19 14.22 13.67 12.66 16.30 15.94 16.89 13.29 15.26 16.24 15.77 16.75 16.32 15.31 14.68 13.66 14.84 14.65 15.61 15.55 14.82 16.01 15.33 16.26 14.07 16.32 16.99 16.29 17.08 15.78 17.44 15.57 13.19 16.93 15.71 15.84 16.99 17.53 17.64 16.86 16.18 16.62 16.81 15.52 14.59 11.15 16.00 15.17 16.04 16.18 13.96 14.86 16.15 14.90 14.86 16.07 13.36 16.50 15.44 16.10 15.91 15.20 15.15 15.33 15.13 15.48 16.79 15.26
VSLGSPSGEVSHPRKT 19.81 14.34 16.40 13.85 14.40 10.57 11.84 11.29 12.72 15.27 17.35 14.00 14.15 15.85 18.18 16.74 10.98 12.74 15.48 13.88 17.82 17.56 14.95 13.87 15.33 12.33 9.80 9.83 12.79 18.09 17.02 21.88 19.70 18.36 11.53 13.33 11.94 14.26 15.53 17.63 16.86 13.79 19.37 11.06 12.77 20.74 14.50 15.70 18.92 17.00 19.18 14.24 15.82 18.52 16.86 14.70 16.73 16.89 13.85 18.16 15.62 13.51 9.40 17.96 15.63 13.60 14.38 9.65 17.17 15.41 13.83 18.87 16.83 18.28 16.18 16.66 19.41 13.07 12.77 13.60 15.25 16.97 19.13 11.36 13.04 15.77 16.63
AKADAAPDEKVLDSGF 16.85 14.55 17.01 13.44 13.76 13.41 15.15 12.80 13.72 14.74 15.29 13.15 12.87 13.21 14.93 15.38 10.90 11.52 15.50 14.35 13.71 10.38 13.42 13.75 12.21 14.77 13.96 3.06 14.18 15.21 15.16 16.41 13.51 12.18 12.09 11.68 12.50 14.15 11.49 15.40 15.24 15.19 15.81 12.25 14.13 17.61 12.45 14.89 16.96 17.68 14.83 13.39 15.44 10.65 15.70 15.21 14.05 15.83 14.49 16.76 14.34 11.55 12.23 13.75 13.55 12.67 13.26 11.59 16.33 12.12 13.76 14.96 14.58 14.33 15.87 13.22 17.11 12.81 15.02 14.79 14.01 7.40 15.33 12.12 14.92 16.59 14.17
VVVHAGEDDLGRGGNQ 14.72 14.22 16.01 10.14 12.77 11.55 10.44 10.80 14.37 12.85 13.73 13.98 10.97 12.30 14.87 11.98 11.28 11.31 12.37 12.07 11.16 13.00 12.32 11.81 12.28 12.43 12.75 11.97 12.90 12.28 13.48 14.73 11.58 11.38 11.79 11.56 11.61 11.08 13.51 12.51 13.18 12.07 15.29 12.06 12.30 15.11 16.23 12.99 14.54 14.15 13.02 14.88 12.82 14.19 13.99 13.02 14.13 13.66 16.93 13.09 12.10 11.53 8.29 9.68 13.53 10.50 11.39 10.74 12.57 12.10 11.44 13.32 14.92 12.35 14.94 13.50 14.14 9.57 14.34 14.25 12.47 12.68 13.38 12.37 13.21 13.27 10.54
ANYPDLPSAYQPGIL 15.28 13.30 15.18 13.43 9.84 12.29 14.54 10.56 14.74 13.19 14.78 13.90 13.85 13.62 12.15 12.33 10.72 9.79 14.60 12.98 11.65 12.60 13.19 13.04 11.42 14.38 13.49 12.04 13.40 12.65 14.22 12.88 12.23 10.61 8.34 12.02 8.62 12.52 13.31 13.02 12.98 13.45 14.39 10.24 12.20 16.15 10.56 13.74 14.65 14.10 13.85 12.74 15.22 12.13 14.88 12.41 14.26 14.83 14.87 14.27 14.42 12.51 13.14 14.61 11.12 12.33 11.67 12.05 15.34 11.38 12.64 13.31 12.62 11.69 13.28 11.26 14.46 10.17 11.26 10.86 11.47 11.57 12.81 12.63 11.67 12.37 12.60
VGGGEQPPPAPAPRRE 18.66 16.66 16.77 16.62 14.59 15.59 16.82 14.04 16.49 16.94 19.04 15.09 15.22 16.56 19.01 18.57 14.83 13.52 17.44 17.20 17.90 18.49 17.95 15.96 14.77 16.92 17.44 15.84 17.90 17.79 18.33 17.31 17.26 16.82 14.54 15.94 14.53 17.79 18.75 18.62 18.26 16.01 19.13 15.05 15.44 19.11 16.65 16.25 18.80 18.26 18.41 18.00 18.09 18.49 18.38 15.63 15.81 17.23 15.81 18.89 16.71 15.56 16.93 16.68 18.83 16.74 17.16 15.04 17.04 17.60 15.41 19.09 18.87 19.37 16.99 18.22 18.14 17.04 15.95 16.42 16.99 19.05 17.46 16.85 17.95 17.93 18.07
SVIDQSRVLNLGPIT 16.87 14.23 15.26 14.10 13.64 12.35 14.05 11.69 14.28 15.45 14.03 12.24 12.50 16.21 16.27 14.32 11.61 12.10 15.41 16.68 15.51 15.97 12.29 14.05 12.67 13.08 15.17 12.19 13.51 10.81 14.68 14.95 13.35 12.91 11.91 11.47 12.75 12.80 13.91 13.12 11.19 12.81 14.77 12.26 9.72 15.32 14.56 13.77 17.91 14.86 15.29 10.93 15.07 17.32 13.73 12.35 13.86 16.40 15.52 14.77 12.84 11.75 13.67 14.01 13.26 14.60 15.45 9.66 14.67 11.82 11.74 14.86 12.63 8.92 10.53 17.13 12.70 12.79 14.19 9.22 11.05 12.30 14.04 7.89 12.57 8.66 12.61
IKFPEPGAIKVPEQG 18.93 16.04 18.70 14.29 14.25 14.01 13.83 12.49 19.97 13.41 16.82 12.55 13.89 15.73 15.73 16.14 12.00 12.15 14.95 13.21 11.51 12.95 16.72 12.70 13.29 15.56 13.97 12.36 12.15 13.95 12.70 17.12 14.11 9.52 10.37 11.75 13.76 15.50 15.76 15.14 15.44 14.37 19.04 12.89 15.24 14.19 14.57 11.61 17.93 16.78 15.96 16.99 17.10 14.41 16.51 17.66 17.57 13.80 16.93 19.45 13.25 11.91 12.83 14.42 15.45 15.15 14.92 13.09 14.43 11.87 11.85 13.29 19.07 16.28 16.37 15.80 17.44 11.57 12.57 14.80 12.35 17.87 15.39 16.13 14.14 17.24 15.55
WQGVEVGEAGQGKDF 15.01 13.87 16.05 12.03 13.34 7.86 10.70 9.52 10.83 11.88 15.12 11.80 12.99 11.61 14.77 13.83 12.33 12.21 13.78 12.17 13.55 11.96 10.26 12.43 9.71 11.51 13.28 13.20 13.40 14.05 15.46 16.32 15.38 14.05 11.61 11.39 12.12 14.27 10.47 13.54 13.54 12.58 15.19 10.49 12.48 16.26 12.24 10.75 14.93 16.16 14.10 14.36 15.31 14.47 10.91 12.78 14.35 10.11 9.77 14.22 13.71 10.32 11.56 11.36 10.66 12.83 14.50 11.96 14.70 12.97 11.60 14.26 13.53 13.70 13.83 17.13 15.07 12.27 13.49 12.97 12.77 12.69 10.02 10.92 12.93 12.84 13.49
IDQSRVLNLGPITR 18.48 12.71 16.70 13.73 10.38 11.87 14.66 9.44 14.78 16.50 18.10 13.57 13.38 14.77 20.05 18.75 10.72 10.97 13.46 14.85 16.02 16.32 16.48 12.89 12.49 12.90 15.33 8.85 12.06 13.94 14.55 16.25 15.69 10.39 12.42 11.39 11.80 16.00 15.14 15.18 15.43 10.11 16.27 11.97 11.88 18.76 13.06 11.95 19.18 17.69 18.17 17.16 19.05 18.87 19.44 15.63 17.30 16.95 18.11 20.87 13.36 11.79 11.23 13.83 16.89 10.25 12.08 11.94 11.63 15.92 9.96 14.16 16.19 16.25 14.95 14.68 14.04 12.50 14.30 12.46 11.94 15.59 14.36 12.75 14.72 14.60 15.57
YLAPNNLKPVVAEF 19.12 13.50 20.42 12.11 9.42 13.31 11.19 13.24 14.92 10.89 16.83 14.19 11.53 13.87 18.33 14.47 11.86 12.36 18.38 12.32 15.87 11.85 12.09 12.95 8.26 13.03 9.71 9.86 10.43 11.16 14.00 13.65 14.44 13.78 13.77 7.63 14.34 13.10 11.52 12.89 12.68 11.15 15.30 10.57 13.87 17.66 11.71 9.82 18.59 16.49 15.67 13.47 13.83 11.90 16.88 12.63 17.07 17.95 13.11 17.26 13.49 13.18 11.92 19.92 12.90 12.99 13.05 8.38 16.05 11.15 9.87 11.82 10.83 12.42 12.89 14.70 14.62 10.87 12.26 12.04 12.36 11.96 15.32 12.93 12.94 14.18 10.86
LRLPEKVPSAPPQE 16.60 14.65 15.07 12.89 13.45 12.66 14.64 10.92 14.94 14.44 13.78 14.04 13.27 13.45 14.99 16.15 12.60 11.18 13.18 13.00 13.83 14.04 12.98 11.70 13.14 13.23 14.47 13.22 13.85 14.74 13.90 15.41 14.19 14.02 12.69 11.44 11.99 15.19 14.75 15.12 15.11 14.25 17.61 12.14 12.96 17.61 12.24 13.71 16.65 17.03 15.18 13.70 16.34 16.49 14.83 14.99 14.72 14.35 14.79 16.63 12.98 11.58 13.01 14.94 10.98 11.73 13.01 12.65 14.72 14.00 12.82 16.77 15.81 17.18 15.59 16.64 17.47 12.87 15.01 12.60 12.97 13.91 15.59 13.45 14.59 16.02 15.60
HSARPGAPPPQPLDL 18.45 14.63 16.32 13.47 9.21 11.94 13.63 9.86 13.86 12.94 16.42 12.94 12.84 11.45 14.72 16.08 12.20 11.17 15.39 14.98 11.13 15.85 14.43 13.46 13.47 13.90 14.70 13.37 14.49 14.52 14.52 16.08 12.32 13.00 10.65 10.71 11.64 14.79 12.87 17.42 12.85 13.62 18.78 5.95 12.50 19.34 12.46 14.63 16.96 18.71 16.05 11.87 16.55 15.46 15.14 10.62 12.97 14.23 13.23 15.83 14.58 12.41 13.10 14.80 15.02 13.78 15.35 13.16 16.13 11.66 14.17 17.11 10.73 17.26 16.96 14.84 18.69 12.59 14.74 12.45 9.85 12.74 16.40 12.22 14.00 15.78 15.65
VAWKADSSPVKAGVE 18.97 16.85 16.10 16.81 15.69 15.78 18.21 10.12 17.43 14.11 18.25 16.63 15.45 16.79 13.65 16.19 11.85 9.89 16.96 16.01 14.40 14.20 13.79 15.61 16.97 15.51 14.94 12.76 15.82 16.71 19.26 20.07 18.03 17.27 15.75 13.84 14.86 16.94 16.17 16.01 16.08 17.77 20.84 14.36 12.95 18.86 13.72 16.93 17.26 20.27 16.30 16.28 17.47 9.85 16.29 15.39 16.06 17.19 17.10 17.74 16.00 14.36 14.24 14.96 12.09 14.74 16.36 13.99 17.83 13.51 14.10 18.17 17.82 16.29 18.45 15.33 19.03 14.87 16.87 17.11 15.02 15.13 17.51 14.53 16.43 17.66 15.76
YRITEATKTVGSDT 15.47 14.10 15.51 12.55 12.15 11.64 13.57 11.87 13.73 14.39 14.16 12.43 12.08 13.14 13.04 12.51 10.03 12.34 13.98 13.02 13.05 13.22 10.93 9.66 11.81 12.90 13.82 12.67 13.66 15.24 15.37 15.45 15.16 13.51 12.79 12.73 13.05 13.69 13.97 14.45 14.61 14.10 15.47 10.09 12.68 14.46 12.31 12.30 16.23 15.59 14.21 13.27 15.41 13.75 12.49 11.99 13.66 13.93 12.99 14.03 14.61 9.15 13.83 14.96 12.91 13.48 13.51 12.11 15.55 12.94 9.39 14.85 15.03 13.81 16.10 10.97 15.59 10.80 14.52 11.82 12.47 14.59 16.29 10.64 14.62 16.81 14.13
TWLNPDPSQKQNL 16.68 14.68 15.91 15.70 14.96 14.48 16.87 13.68 14.27 15.72 14.80 13.90 15.25 13.86 14.19 13.29 10.79 13.51 14.67 12.41 12.89 13.44 11.92 13.73 13.59 12.25 10.46 11.27 14.78 14.43 15.50 14.57 13.27 13.17 12.94 12.65 13.83 15.10 14.97 14.17 15.51 14.32 14.83 11.72 14.81 16.99 12.23 17.03 16.14 17.27 14.85 13.83 15.94 15.56 15.03 15.91 15.14 15.15 15.24 15.24 14.12 14.93 12.58 14.18 8.40 12.68 15.27 13.01 14.38 10.25 11.62 13.86 13.73 14.44 16.16 12.32 16.28 13.93 16.23 14.17 13.54 13.66 14.87 12.94 15.00 17.31 14.15
SIDWTKIEPSVNF 15.05 13.40 14.17 11.92 11.18 11.63 12.89 10.53 13.16 10.03 13.73 12.40 13.13 12.11 14.79 12.24 11.25 10.76 14.27 10.42 10.75 11.32 10.16 11.14 10.70 10.49 12.38 12.19 10.41 12.31 13.68 14.52 12.82 13.03 12.39 11.82 12.66 13.19 12.07 12.93 13.07 11.68 15.68 11.89 11.62 15.09 16.23 13.08 13.83 15.18 12.45 12.72 13.83 12.59 12.84 12.51 12.65 13.19 16.93 14.31 12.85 8.30 9.11 12.41 13.22 11.64 11.00 9.72 13.89 12.36 11.29 14.66 12.54 12.67 12.58 13.50 14.78 8.17 9.57 12.83 12.90 12.95 13.26 12.62 11.04 12.77 12.08
IEVDGRVYHVGLGD 13.57 13.58 15.55 13.24 13.14 10.39 10.74 11.46 13.03 13.96 16.22 12.86 14.23 12.63 13.05 8.21 10.71 10.48 13.71 13.63 14.48 15.76 13.02 12.48 12.96 12.51 14.07 10.14 12.99 11.54 13.63 13.77 10.66 12.01 12.52 11.92 13.69 12.54 12.87 13.61 12.89 14.26 18.27 11.15 12.04 13.57 16.23 14.55 13.87 14.86 13.96 17.43 17.06 11.16 14.87 13.40 13.15 14.15 17.06 14.79 10.79 12.24 11.03 14.10 12.60 11.35 14.92 12.24 13.21 14.75 12.80 13.68 12.47 10.07 14.45 11.26 13.72 12.57 15.38 13.16 12.99 11.31 13.36 12.55 13.01 14.99 12.28
YQAEWDDYVPKL 14.79 14.11 14.72 12.65 10.42 11.84 6.95 10.45 14.50 12.55 15.45 14.27 13.14 13.21 15.64 13.49 10.99 11.38 11.81 13.89 11.56 13.77 14.00 11.81 11.33 9.62 12.71 11.21 12.71 12.65 12.20 13.50 13.25 12.06 12.13 11.75 12.56 13.02 13.43 15.35 12.71 12.21 15.12 12.59 13.56 14.51 11.71 12.56 15.63 13.58 13.63 13.70 16.75 16.59 15.88 13.36 14.00 14.78 16.30 14.38 11.95 11.97 9.88 13.88 11.23 12.17 10.62 12.07 11.47 11.71 9.76 13.37 13.14 12.85 13.56 17.13 12.97 11.50 13.68 9.78 11.97 13.25 13.97 11.93 12.36 11.08 13.09
VIDQSRVLNLGPIT 13.41 7.21 15.92 12.85 11.01 10.96 12.49 10.27 14.23 14.39 14.60 11.92 11.14 13.69 15.14 13.97 10.45 9.00 14.62 15.35 13.96 14.24 11.64 10.61 9.78 14.27 14.22 12.15 12.07 12.41 10.13 13.31 11.77 12.59 10.58 11.24 11.08 9.18 13.35 11.48 7.27 11.45 14.73 11.02 7.76 12.63 13.46 12.65 14.48 14.77 12.04 12.26 13.62 13.98 13.96 11.18 12.01 15.12 12.89 15.79 12.36 11.69 15.05 11.39 11.07 11.72 12.74 11.68 12.34 12.08 12.73 9.71 11.16 11.28 12.17 13.50 12.00 11.55 11.89 7.96 10.85 11.60 13.51 11.64 11.79 11.97 11.10
ISQDNALRDEMRA 14.35 13.56 12.55 14.62 13.51 13.98 14.79 12.26 15.15 13.30 15.41 13.96 13.45 14.47 13.80 13.31 11.19 10.99 11.36 11.97 11.44 11.05 12.41 14.31 13.74 13.49 13.13 11.49 13.91 14.14 16.69 16.74 15.12 14.61 12.71 13.06 12.29 14.88 14.14 14.51 12.67 14.71 15.90 10.45 11.47 15.39 10.34 13.91 12.60 17.55 12.72 13.75 14.65 13.22 13.44 14.16 13.41 14.03 13.69 14.97 14.22 12.98 12.50 13.42 12.58 11.90 13.42 12.90 15.26 12.79 12.59 15.48 14.59 14.18 14.90 11.26 14.77 12.42 14.94 14.24 13.71 11.99 14.06 12.64 13.03 14.21 13.68
FDSDPITVTVPVEV 13.61 13.39 15.70 11.89 12.69 12.17 13.35 11.33 14.15 15.79 14.03 14.14 13.02 13.34 14.40 11.88 10.39 11.60 13.59 12.72 11.49 12.82 12.69 12.63 12.31 14.12 11.45 10.63 15.52 14.50 16.08 15.23 14.10 13.57 12.58 10.98 13.41 14.23 15.85 14.82 15.00 13.57 14.54 12.29 13.33 13.92 11.42 13.32 13.35 14.28 12.29 13.75 14.40 13.63 14.35 14.22 14.51 14.26 13.41 12.40 13.58 11.33 12.11 15.58 9.83 11.11 13.41 11.80 13.56 10.99 13.23 14.31 14.03 12.53 14.82 15.00 15.28 14.31 14.01 12.74 12.65 12.45 14.55 12.65 14.80 15.54 12.94
VAWKADGSPVKAGVE 16.54 14.33 16.10 13.65 13.56 12.94 14.39 12.71 15.84 12.82 15.51 12.72 13.41 13.37 15.13 14.34 11.14 10.43 13.84 12.80 15.09 15.83 10.67 12.99 13.91 13.60 14.68 9.87 12.85 13.76 16.49 17.47 15.10 15.12 13.34 11.86 11.76 14.45 13.04 14.15 13.07 15.12 18.59 12.22 13.50 15.32 12.55 14.22 14.30 17.48 14.53 12.25 15.94 12.37 14.81 13.36 14.48 14.89 14.04 15.57 13.40 12.08 12.64 13.54 13.11 11.75 13.66 11.84 14.85 11.84 11.67 14.92 15.59 13.67 16.48 12.43 16.23 12.28 15.21 14.40 12.05 12.26 16.17 12.33 14.32 15.95 12.49
PRGHSGEPGLPGPPGP 16.45 15.09 16.34 15.11 14.33 16.00 14.84 13.48 15.46 14.53 16.65 15.49 13.10 13.86 14.23 15.58 12.16 15.09 16.12 14.99 16.15 16.61 16.42 15.30 14.97 16.79 17.62 16.18 17.41 17.29 16.59 15.34 15.12 15.73 13.54 15.10 12.99 15.56 17.46 17.11 16.45 15.45 17.56 14.93 15.38 15.57 14.98 14.57 16.98 15.41 14.41 15.86 15.87 16.71 16.96 16.92 16.26 16.23 15.33 15.96 16.36 16.09 17.44 15.51 15.62 16.41 15.51 15.37 16.38 16.24 15.61 16.30 16.79 17.87 16.37 15.50 16.61 15.52 15.22 15.72 15.86 17.03 16.76 16.75 16.27 16.01 17.10
G(+42.01)DKPIWEQIGSSF 15.70 13.04 15.43 11.57 11.18 11.81 13.67 10.54 13.78 13.85 15.74 10.40 13.23 13.52 14.75 12.94 10.56 10.60 15.68 15.08 13.52 14.18 13.34 14.01 12.49 12.93 11.49 11.73 13.09 13.57 13.41 14.30 13.20 12.64 11.82 11.31 12.42 12.99 14.14 13.17 13.06 13.14 15.33 11.35 11.79 15.00 12.53 13.03 15.40 15.48 14.84 14.85 15.27 14.56 15.66 13.00 13.30 14.52 12.69 14.53 12.95 12.27 11.40 15.21 11.76 12.80 13.27 11.91 15.20 13.21 12.06 13.10 12.05 13.16 13.42 14.34 14.39 11.78 12.93 12.01 12.50 13.06 13.61 12.08 13.00 13.01 13.08
VHLTPEEKSAVTAL 15.23 13.70 19.88 16.26 12.83 15.05 14.64 13.04 14.58 14.54 17.60 13.61 14.49 14.85 19.61 16.15 10.56 7.40 16.13 16.66 15.18 15.48 13.11 12.84 12.78 12.89 15.17 14.68 16.03 16.94 14.00 13.25 13.91 12.87 12.18 9.10 11.81 14.18 17.98 12.83 13.53 17.06 13.15 12.30 14.31 17.12 15.17 15.89 21.11 14.49 17.83 11.05 16.41 17.46 17.03 13.28 15.98 16.27 16.78 19.36 16.37 14.04 12.80 24.77 15.47 14.38 15.72 11.77 13.68 11.04 14.97 17.31 17.99 18.12 14.67 17.15 18.12 11.34 13.81 16.06 12.99 15.27 24.99 16.78 15.96 18.03 16.48
WGSPAASDDGRRTL 15.75 14.53 15.08 12.33 12.88 12.42 13.08 11.13 14.32 13.74 14.19 13.10 13.17 13.65 15.04 14.62 12.06 11.01 13.31 12.46 15.09 15.65 13.87 13.28 12.36 12.98 14.33 13.19 14.07 13.49 13.53 15.23 13.60 12.66 12.10 11.16 13.06 13.34 14.99 15.18 14.15 15.67 17.90 11.13 12.97 17.37 12.24 14.59 15.11 16.82 14.74 14.75 15.36 14.59 14.66 11.88 13.91 14.02 14.74 15.55 11.19 12.84 13.11 13.80 13.51 13.72 13.79 11.12 16.04 14.84 13.39 15.23 12.40 15.59 16.61 13.91 17.94 12.89 15.50 11.42 12.32 14.09 14.63 12.68 14.69 14.66 13.31
FRVVAQGVGIPEDS 16.79 15.65 17.40 15.46 15.38 12.77 14.60 12.75 16.03 14.04 18.40 14.97 15.60 15.79 11.81 14.91 13.02 10.12 17.70 13.09 11.63 12.15 10.80 13.47 15.75 14.21 13.33 9.91 14.51 16.26 17.64 17.44 16.90 14.42 13.51 9.89 14.42 15.64 15.95 15.94 13.60 15.83 18.37 13.40 12.31 17.62 16.37 16.32 18.10 19.08 14.45 16.26 17.33 16.68 16.22 15.93 14.96 17.70 14.81 16.75 15.47 13.85 11.67 15.26 12.94 11.93 11.78 14.55 16.96 11.24 14.83 17.74 15.42 15.61 16.51 15.61 17.42 13.62 17.03 12.58 13.64 15.02 16.84 12.89 15.72 17.18 14.61
WGKVNVDEVGGEAL 15.00 13.90 19.05 14.36 13.30 11.88 13.22 12.51 13.87 12.06 13.81 13.90 13.27 13.49 15.31 12.96 11.34 12.14 12.87 13.02 8.60 14.45 8.99 13.08 12.46 12.08 13.50 11.36 13.49 12.27 10.64 15.19 13.61 13.47 11.92 10.36 10.38 11.00 14.50 13.71 13.46 15.10 13.92 13.12 13.77 14.95 11.37 15.99 16.18 14.79 14.54 13.36 15.97 14.90 16.01 12.41 14.68 14.01 15.62 15.79 12.56 12.40 12.52 21.76 14.51 11.30 14.53 9.35 10.91 13.66 10.90 14.51 13.31 13.95 11.85 17.13 15.13 12.71 13.18 12.16 13.24 13.93 21.00 14.76 12.62 16.40 14.24
DQSRVLNLGPITR 17.59 12.10 13.95 13.17 9.32 12.46 15.37 12.43 14.06 15.81 18.03 14.61 14.10 14.64 20.12 18.45 11.42 11.87 14.99 13.67 15.86 15.78 15.93 14.83 13.04 11.31 14.91 11.43 12.42 15.17 14.27 16.70 16.22 11.91 12.63 12.43 12.41 15.49 14.73 14.68 15.38 14.30 15.47 12.05 13.23 18.29 12.03 11.43 19.51 17.11 18.17 16.64 19.53 18.04 20.02 15.23 17.28 16.33 18.25 20.31 13.29 12.48 10.52 13.22 16.20 14.26 13.04 12.38 14.81 15.24 9.39 14.74 15.44 16.15 15.02 13.87 15.87 12.13 14.60 13.22 14.89 15.08 14.58 12.72 14.24 14.32 16.06
IQLQPLQEPESW 13.60 12.56 12.56 12.06 9.84 11.67 11.81 11.31 11.77 12.99 8.94 10.59 13.09 12.97 13.95 14.02 11.25 10.09 12.88 13.51 9.70 10.62 9.34 10.08 11.41 11.63 12.90 12.32 12.87 11.53 11.91 12.21 11.07 12.40 10.71 12.34 10.94 12.47 10.37 12.51 13.12 12.42 16.79 9.10 12.17 14.45 10.34 12.93 11.52 14.86 11.91 11.96 13.96 14.24 12.24 12.51 11.60 12.68 12.29 12.17 11.80 10.79 12.27 12.71 11.81 9.77 13.44 12.62 13.75 13.06 12.37 12.71 10.21 11.87 13.66 11.26 13.94 11.74 14.81 10.82 8.98 11.99 11.98 9.84 12.05 14.42 10.83
DHDVGSELPPEGVL 15.99 16.82 16.45 16.27 15.70 14.83 16.31 14.35 16.18 14.38 16.00 13.42 15.62 14.40 16.02 14.77 10.97 12.39 15.08 14.13 13.49 13.68 13.31 13.96 13.43 14.71 11.17 11.62 15.88 15.79 17.72 16.91 16.10 15.12 13.90 13.07 14.27 15.23 16.12 15.35 14.94 15.37 17.41 14.08 14.83 16.84 12.00 16.71 14.31 17.22 14.91 13.65 13.89 14.68 15.40 14.42 15.97 15.72 12.81 14.85 15.27 14.26 13.64 15.25 14.00 12.64 15.12 12.73 15.62 11.69 14.01 15.09 14.60 14.67 15.98 13.20 16.32 14.19 16.48 15.70 15.67 13.77 16.36 14.14 14.78 16.45 14.88
SQDASDGLQRLHM 18.11 15.67 15.80 15.83 9.89 13.96 16.27 13.18 15.29 13.00 15.07 14.63 15.67 15.56 16.60 15.86 12.28 11.61 14.56 15.50 16.93 16.51 15.08 14.61 14.34 15.81 11.77 12.96 16.59 16.79 16.40 17.20 17.56 15.21 13.63 9.00 13.60 16.19 16.43 16.82 17.17 15.48 17.42 12.66 13.56 18.08 14.66 14.92 17.89 18.35 16.99 15.59 16.59 15.81 17.07 15.03 16.38 16.52 13.73 15.47 17.02 13.88 13.77 15.22 14.82 15.23 14.51 14.82 18.55 14.76 13.43 16.01 15.81 15.96 17.51 11.49 17.38 12.51 17.35 15.74 15.16 14.38 17.20 15.07 13.77 17.36 16.26
IDWTKIEPSVNF 18.73 13.74 16.80 12.15 9.21 14.44 13.73 11.18 13.80 14.04 16.45 12.22 13.61 14.09 15.81 15.82 12.54 11.33 17.11 13.96 13.71 14.70 13.61 14.07 12.74 13.48 15.04 10.91 13.93 15.49 16.00 17.14 15.95 13.22 10.93 10.34 11.97 15.13 15.58 16.09 13.71 15.46 19.14 8.81 13.48 18.77 14.07 12.79 17.18 18.48 15.75 16.09 16.61 16.75 16.19 12.95 14.22 15.88 12.78 17.32 15.11 10.37 11.78 15.60 13.08 10.49 12.67 12.69 16.94 12.81 13.26 17.88 15.28 16.69 15.49 13.17 18.30 11.62 13.77 11.56 11.74 16.14 16.13 10.24 14.79 15.84 15.27
AWKADSSPVKAGVE 15.32 13.64 15.33 12.50 13.50 12.42 13.42 10.80 14.17 13.52 15.64 12.55 12.43 12.76 14.81 12.87 12.37 12.40 13.77 11.92 14.00 14.31 12.32 12.48 13.83 13.12 13.56 12.96 13.20 13.48 15.05 16.55 14.29 13.71 12.55 11.23 11.94 12.14 14.38 13.87 12.18 14.95 17.24 11.63 12.55 14.57 12.97 14.05 13.90 16.14 13.01 17.43 14.18 12.72 13.96 12.02 13.87 13.84 12.88 15.40 13.01 11.62 13.77 12.67 12.85 12.05 12.97 11.92 14.80 13.27 12.74 14.53 13.85 11.86 14.73 12.22 15.95 12.94 14.80 12.79 13.08 13.05 14.18 13.48 13.34 14.36 13.25
VNVDEVGGEALGRL 16.93 12.19 18.52 11.88 10.11 12.41 14.68 10.86 13.05 13.59 15.86 12.69 13.21 12.30 14.37 12.71 10.94 10.52 12.73 11.83 9.78 14.28 13.21 11.64 10.86 10.49 10.67 11.28 12.86 13.64 13.39 13.79 13.10 12.44 8.34 11.57 13.15 12.40 12.15 15.14 12.64 12.91 15.60 12.06 12.07 16.94 9.23 11.88 14.27 16.34 14.52 13.25 16.13 14.83 14.72 10.97 13.03 13.18 14.48 12.08 11.17 11.41 11.87 17.70 13.06 11.97 12.17 10.80 14.36 12.41 11.44 13.76 13.05 13.92 13.93 13.94 14.99 11.48 12.13 12.04 12.53 13.26 13.05 11.72 12.89 15.20 13.18
YADKPETTKEQL 15.38 13.78 16.02 14.79 12.79 11.68 13.98 11.08 13.03 11.54 15.30 12.31 12.99 13.52 13.87 15.25 12.14 8.33 15.05 13.95 15.03 14.81 12.82 12.69 12.42 14.45 15.01 13.47 15.19 15.35 15.15 15.33 15.28 14.75 15.27 12.52 14.69 14.59 15.49 15.68 15.23 13.74 15.78 13.14 12.62 15.45 12.46 14.80 17.01 15.34 14.54 12.97 15.55 15.11 15.75 12.41 14.44 14.12 12.62 17.14 13.53 13.10 14.53 14.08 13.40 14.19 15.63 12.43 15.12 15.03 13.51 15.47 15.66 15.05 14.71 12.77 15.88 14.83 13.99 14.38 14.97 14.79 15.49 14.76 14.44 15.57 15.57
TVDKSRWQQGNV 19.64 14.60 17.75 13.46 12.64 13.83 14.22 11.56 14.77 13.31 15.85 14.67 13.10 14.19 15.89 14.61 12.54 11.01 14.78 15.46 12.45 12.27 12.46 13.99 12.75 13.20 14.60 12.97 15.36 14.11 16.37 17.71 15.31 13.86 11.07 10.54 12.50 14.05 15.00 16.77 15.70 13.93 22.39 12.36 13.05 18.44 13.89 13.81 15.67 18.86 15.56 16.36 15.38 14.79 13.43 13.68 14.70 14.93 12.61 16.14 11.85 10.15 14.12 13.93 13.49 14.32 15.08 13.08 15.69 14.55 13.49 17.01 16.51 17.23 16.29 15.81 19.26 14.49 15.00 13.40 13.98 15.99 17.03 12.83 14.65 16.95 15.94
LRLTEPADTITDA 15.07 15.55 14.82 13.39 13.20 12.76 15.23 12.12 15.21 13.78 14.78 12.46 13.79 13.09 14.28 13.53 12.05 10.01 14.52 14.15 10.62 10.18 10.35 11.73 14.22 14.14 12.11 10.43 11.46 16.61 15.96 15.91 14.56 13.81 11.44 10.96 12.53 14.81 15.73 15.32 14.76 12.03 15.65 13.01 13.12 15.28 12.97 14.70 14.15 12.90 13.36 12.25 16.55 14.01 15.78 14.55 15.96 14.45 13.42 15.80 14.03 11.71 13.82 14.72 11.07 11.84 13.21 12.96 14.38 11.93 13.31 15.18 15.04 14.74 12.49 13.32 16.30 14.89 16.04 12.94 15.48 15.16 16.38 13.24 15.30 16.72 14.83
VSLGSPSGEVSHPR 18.14 14.23 15.29 12.77 13.32 13.10 13.85 11.63 9.69 14.54 15.65 13.76 14.41 16.12 14.90 14.03 11.52 12.45 12.57 13.95 16.41 15.15 12.95 14.04 14.35 14.27 14.80 11.73 13.11 17.96 15.71 21.10 17.78 17.74 13.18 14.08 14.20 14.22 15.47 14.85 16.43 15.27 18.72 12.18 11.72 18.25 14.08 14.90 17.97 17.24 18.27 13.18 16.06 15.93 13.76 12.04 16.15 16.22 14.36 17.62 16.64 12.85 12.20 16.09 13.91 14.40 14.95 13.99 16.66 14.36 13.90 16.49 15.12 15.86 15.17 11.24 18.53 14.89 15.47 13.54 15.40 15.08 17.96 13.84 14.89 13.37 14.80
DGVPGKDGPRGPTGP 17.19 15.30 16.78 15.24 13.02 14.13 15.17 13.83 15.89 15.07 17.35 10.36 14.34 14.63 12.80 16.98 12.23 12.01 17.05 17.08 17.23 16.77 17.38 14.74 14.88 15.96 17.32 15.58 17.28 17.98 17.48 17.54 17.37 16.86 14.06 14.85 15.02 17.00 17.61 18.17 17.41 16.09 18.04 14.98 15.64 18.10 15.40 14.76 17.48 17.27 17.58 15.19 17.10 16.25 16.74 15.76 15.97 16.04 15.36 16.91 16.05 15.27 16.56 15.52 17.06 16.11 17.24 14.19 17.22 17.35 15.48 17.01 17.44 17.31 16.24 14.18 18.01 17.07 15.41 16.49 16.98 18.03 17.66 16.54 16.56 17.65 18.25
AGKQLEDGRTLSD 14.44 15.11 14.68 13.81 14.50 14.91 14.64 12.61 13.28 11.30 14.96 13.87 14.56 12.88 14.77 13.79 8.63 13.19 12.01 12.15 14.18 10.69 13.26 14.11 14.34 11.78 12.75 9.90 13.76 13.56 14.47 13.88 13.23 14.00 15.58 13.09 15.50 13.03 13.56 13.30 13.25 15.22 14.63 14.42 13.96 14.24 10.34 15.81 14.31 15.41 12.96 13.10 14.17 13.85 14.75 15.96 13.02 13.83 13.44 14.22 11.97 14.32 12.46 13.92 11.11 13.35 13.63 13.89 13.43 8.34 10.29 13.86 13.92 13.33 15.96 15.00 13.68 11.89 16.18 12.30 13.12 13.30 13.61 14.20 13.35 13.90 12.98
SSSERAHQVLRI 16.31 12.94 13.33 13.49 13.06 13.58 12.49 10.80 14.06 13.73 15.50 12.64 13.67 13.57 15.06 14.13 12.06 11.33 13.51 15.26 9.65 15.87 12.76 10.22 12.30 11.98 14.50 13.26 14.09 14.84 12.87 14.92 14.17 13.26 12.01 10.54 11.66 12.81 15.61 14.83 12.39 13.60 18.16 11.80 12.28 13.64 12.97 13.41 15.69 15.56 15.94 17.26 17.31 12.84 14.69 12.70 13.76 12.79 14.05 14.04 10.29 12.78 13.76 13.54 15.54 13.94 15.23 12.73 13.11 10.15 13.53 16.57 15.13 16.90 14.76 15.01 16.86 12.89 12.68 12.71 12.56 14.65 13.44 12.58 13.43 14.93 13.76
PVAEELSHHENL 14.91 14.58 17.11 13.52 11.31 12.39 14.12 12.84 13.67 12.56 16.33 13.15 12.99 13.43 15.20 15.26 11.94 11.47 14.96 14.46 15.23 15.17 12.74 13.01 12.96 13.60 14.11 12.26 15.61 16.19 16.54 17.52 16.29 16.33 11.57 13.49 12.60 15.06 15.29 14.48 15.54 14.42 14.41 12.30 12.57 16.03 11.73 12.69 16.47 16.74 15.54 13.09 14.21 14.06 14.86 12.56 14.48 15.14 14.49 16.70 15.60 12.11 13.64 15.26 13.55 13.40 15.44 12.91 15.24 14.11 13.12 16.13 14.27 14.23 15.00 13.06 16.01 13.97 14.75 14.78 14.78 14.67 16.12 14.07 15.38 15.60 15.35
AVALTKGGEARGEL 16.65 13.63 16.15 13.84 8.63 13.68 13.41 10.85 10.22 14.22 13.85 12.73 11.61 12.59 15.83 12.43 11.88 10.40 16.78 14.36 14.35 14.09 13.28 12.13 10.95 13.79 11.30 13.35 15.59 15.93 15.74 15.68 15.55 13.49 10.46 11.95 10.99 15.12 16.83 15.94 15.69 13.97 15.80 11.89 12.84 16.70 11.88 11.49 16.94 18.04 14.13 12.91 16.17 11.99 14.87 13.74 13.65 15.50 14.69 16.45 13.99 10.59 9.68 12.42 11.92 13.51 15.09 10.95 15.94 11.34 11.41 17.28 15.08 15.35 12.66 13.36 18.15 12.65 15.59 13.53 11.92 14.78 16.28 14.67 16.45 15.64 14.87
PENEKGPFPKNL 16.09 13.00 18.82 13.60 13.39 13.54 12.61 10.59 14.73 14.05 16.16 12.66 12.83 13.52 14.88 14.15 12.39 11.35 13.55 13.72 14.83 15.37 13.53 9.81 12.59 12.46 15.26 14.13 13.99 13.24 17.30 17.47 14.47 13.39 11.72 13.36 12.17 15.40 14.66 14.07 12.79 14.23 19.11 11.74 12.68 16.46 12.24 13.67 16.40 17.83 15.52 14.03 14.25 13.83 16.01 13.08 14.12 13.88 16.93 16.14 14.24 13.56 14.22 14.11 11.92 13.74 12.27 10.32 13.90 12.20 13.43 17.23 13.84 14.09 15.12 15.92 17.08 13.55 14.17 13.66 13.18 15.13 13.95 12.03 11.73 15.34 14.11
TPLGPKWPEPVF 19.65 14.55 17.91 14.69 15.08 13.99 16.57 13.26 16.53 14.43 15.90 16.01 16.07 15.78 18.74 17.47 12.53 12.48 16.50 14.12 17.23 16.84 12.63 16.22 15.12 14.52 16.17 12.49 15.89 16.39 14.06 19.60 16.68 14.03 13.25 13.77 12.52 14.97 13.42 18.23 13.29 14.72 17.17 14.54 12.67 20.36 11.35 13.69 19.58 20.96 18.91 14.25 16.31 18.56 16.87 14.13 17.33 18.61 16.33 21.39 13.60 14.32 12.19 15.17 12.65 14.55 15.16 13.41 18.06 16.21 14.62 13.76 15.30 17.73 18.55 13.88 17.64 15.27 13.13 11.25 12.97 16.08 19.02 12.41 13.46 17.41 16.45
VKVWPQQPSGEL 17.06 11.85 16.80 11.74 12.08 13.34 13.55 10.00 13.73 13.26 14.57 13.52 12.70 12.44 14.92 14.17 14.70 12.70 13.93 14.88 12.22 10.01 12.72 10.54 12.48 13.23 13.89 11.84 11.87 15.98 15.32 18.71 17.48 14.36 10.20 11.86 12.34 12.06 11.88 13.49 12.96 13.37 18.48 14.09 13.01 17.76 13.46 12.46 16.10 16.61 15.43 13.13 14.50 14.03 13.21 12.41 10.07 15.04 13.92 16.66 13.18 11.24 14.00 14.97 12.76 10.08 13.95 11.72 15.61 9.35 12.24 15.12 13.84 14.01 13.67 11.65 17.24 10.07 13.15 14.47 12.84 13.82 16.20 12.00 12.78 15.08 13.30
RAHGQESAIFNE 17.36 11.08 16.27 14.08 13.50 13.47 9.35 9.52 13.69 10.28 15.51 12.73 13.18 13.06 13.84 14.68 13.31 11.31 12.96 12.31 13.47 15.54 12.32 12.98 12.98 13.07 12.91 7.76 14.26 16.35 15.19 17.15 14.89 14.04 9.38 11.39 13.41 15.13 15.43 16.47 14.41 13.85 13.22 13.01 12.00 18.06 11.86 11.96 15.81 14.72 15.03 16.03 14.19 15.69 14.93 13.39 14.53 14.44 14.21 16.15 11.94 13.03 14.17 14.39 14.24 11.00 14.90 12.38 15.41 12.02 11.33 15.92 14.54 16.98 13.52 12.42 16.65 11.85 13.56 13.72 13.84 16.20 16.58 12.06 13.79 14.63 15.89
FQVRANSAGATRA 17.17 14.37 16.77 15.12 14.65 14.79 15.66 12.70 15.79 13.74 17.80 14.67 14.38 14.30 15.96 15.76 14.70 11.28 13.41 12.59 13.94 13.17 10.97 12.50 14.36 12.30 14.61 12.11 14.77 14.92 17.46 18.89 17.18 15.90 12.05 12.60 13.32 15.56 15.78 14.20 13.97 15.29 18.27 13.19 12.69 17.45 16.23 15.60 16.97 19.34 15.93 14.25 17.07 16.09 16.48 14.94 15.11 14.87 14.69 17.80 13.60 13.23 11.74 13.00 13.51 12.84 13.71 13.69 15.72 15.29 13.29 18.82 16.34 16.35 15.40 14.38 17.10 13.22 15.84 14.14 12.53 14.57 16.31 13.91 14.67 15.40 15.00
LVIKGARDSHAGL 19.10 14.93 17.24 14.96 13.29 13.29 14.48 11.78 14.69 14.55 18.09 13.85 14.46 14.55 18.50 14.99 13.24 11.00 14.53 15.41 15.70 17.16 14.17 12.86 13.49 14.30 13.23 12.80 14.41 16.16 16.44 18.47 16.30 14.45 12.85 11.61 12.24 16.99 16.24 18.70 15.02 15.15 18.07 12.11 12.53 19.89 14.93 15.39 18.91 19.07 18.58 17.99 17.30 18.53 17.55 15.11 15.61 16.46 14.96 17.11 13.20 13.36 12.72 14.33 14.52 13.46 14.75 13.56 15.86 14.01 12.03 18.84 17.00 18.35 16.43 15.51 17.29 13.32 14.07 13.73 13.07 17.08 16.65 13.76 12.99 15.88 16.46
ANKADRDQYEL 18.30 13.94 16.23 13.56 13.52 13.16 14.13 11.34 15.17 13.71 15.35 12.66 13.24 13.33 14.59 14.36 12.18 10.73 16.10 11.79 13.42 14.23 13.80 12.12 12.23 13.56 13.81 12.06 13.49 12.33 15.44 14.09 13.99 10.42 12.09 11.23 12.23 13.02 14.53 14.15 14.11 13.19 17.21 13.63 12.60 16.52 12.24 14.11 16.67 16.83 14.03 13.71 15.32 10.20 13.69 13.66 15.16 14.64 13.42 14.99 12.98 12.00 14.55 14.72 13.26 13.83 15.04 12.74 14.64 6.72 13.03 14.75 13.76 13.91 13.67 13.32 15.90 11.67 14.85 14.07 13.47 13.76 16.19 12.10 14.40 15.35 14.40
YSRTQTPRAEL 16.43 16.42 14.23 15.94 16.23 15.78 14.72 13.62 15.84 13.68 14.58 15.43 15.43 14.31 15.23 13.47 12.76 11.81 15.50 14.65 13.04 10.58 13.65 14.43 14.85 13.40 15.32 13.46 12.96 14.19 16.74 18.28 14.29 16.18 14.14 14.15 13.39 15.07 13.82 14.39 13.46 14.04 18.25 12.68 13.03 16.57 12.24 17.05 13.85 17.39 15.57 15.42 15.69 13.68 15.13 12.88 14.81 15.24 14.69 16.64 13.97 13.75 12.06 13.64 13.15 12.96 13.07 13.45 15.99 12.02 13.54 18.79 15.10 17.55 16.66 13.13 17.06 13.78 15.28 13.33 13.13 14.60 15.61 12.02 16.52 15.26 13.08
RAPEPALEPESL 16.04 14.45 15.58 13.16 11.15 11.94 13.57 11.46 13.58 13.65 15.51 13.29 11.92 13.53 14.25 12.33 9.47 9.15 14.68 11.89 12.79 10.14 10.89 11.01 10.40 13.16 9.52 11.71 12.76 12.96 14.34 14.40 13.19 12.71 10.62 10.86 12.42 12.22 13.68 13.50 12.88 12.56 16.11 12.32 12.67 15.36 13.34 12.84 14.27 16.12 12.22 13.77 15.43 13.43 14.05 14.24 13.13 16.24 13.88 14.23 13.60 12.29 13.38 14.46 16.99 10.25 12.03 13.03 14.39 12.37 12.05 13.52 11.24 11.46 14.26 17.13 14.08 12.20 14.66 12.00 12.25 12.45 15.23 11.37 10.78 14.75 13.47
VVENGESSQGRF 15.27 14.47 18.33 15.50 13.97 12.78 13.99 14.22 14.20 14.01 16.57 15.38 12.54 15.32 14.83 14.51 12.96 11.45 14.02 13.45 12.82 14.81 13.93 12.46 13.25 13.28 13.46 12.06 15.38 16.28 14.76 17.31 15.04 14.32 14.04 14.44 15.65 11.02 8.06 9.92 14.23 14.77 15.36 13.63 12.03 15.89 12.88 14.38 13.97 15.72 14.85 14.45 15.41 14.50 14.42 12.49 13.69 14.52 13.49 17.35 14.23 9.75 8.11 19.47 14.75 11.16 14.01 12.77 13.09 14.47 12.65 16.09 14.75 15.22 15.69 15.18 15.75 11.70 15.88 14.86 12.94 14.33 18.55 11.28 14.10 16.34 14.91
AASLAGPHSIVGRA 17.10 11.42 16.02 10.77 9.48 11.21 13.78 10.63 11.93 12.95 16.77 12.86 11.84 11.62 16.78 16.69 10.73 10.77 14.56 14.40 15.79 15.42 12.70 12.56 12.27 13.83 11.80 13.55 13.05 15.56 12.60 15.20 15.63 12.73 10.37 12.70 13.04 14.85 13.88 14.26 15.53 13.13 13.87 12.78 12.38 18.10 12.51 14.24 18.05 18.28 17.89 15.71 16.78 16.18 15.69 13.09 15.12 16.53 12.72 17.86 13.73 10.73 11.33 14.21 13.79 11.14 12.69 12.50 14.32 13.37 12.47 15.98 16.56 16.52 15.85 11.49 16.04 12.22 12.89 12.13 13.36 16.14 15.87 13.11 14.65 13.62 15.51
YGRAPQLRETL 19.69 15.12 18.01 14.53 13.82 12.69 15.88 11.14 16.63 14.83 23.16 16.22 15.57 16.86 18.58 12.10 12.19 11.47 18.75 15.22 15.31 14.87 16.24 12.49 12.06 14.53 12.97 9.93 16.09 18.08 19.32 20.47 19.80 15.82 12.93 12.82 12.27 18.56 19.63 19.29 16.00 16.22 19.16 13.19 11.06 21.26 12.46 14.24 18.19 21.61 18.70 18.67 20.00 19.09 20.13 16.70 16.25 19.39 17.75 20.22 15.12 13.13 12.49 12.38 14.84 12.48 13.31 12.81 17.53 15.10 14.78 22.09 19.14 19.16 14.10 20.06 13.55 14.55 15.84 13.82 13.80 19.08 18.90 13.97 17.90 17.83 18.00
YVVHTNYDEY 16.78 14.34 15.09 14.41 14.32 7.82 13.86 11.91 14.19 12.89 16.23 12.86 11.98 12.96 14.69 13.86 10.34 7.92 12.63 14.66 14.84 15.37 9.02 12.42 13.13 12.47 13.35 10.72 14.37 14.57 16.37 16.22 15.85 14.63 11.82 10.64 12.36 14.31 14.91 13.82 13.86 13.65 15.26 11.89 10.91 16.16 16.23 14.33 15.03 14.94 14.34 14.96 14.81 13.99 12.58 12.98 12.51 13.58 13.58 14.49 13.98 11.24 12.77 12.11 13.26 12.50 13.26 8.22 13.59 16.29 13.64 15.99 13.01 14.67 14.73 12.12 13.64 13.31 15.06 12.79 13.31 11.28 14.50 12.20 13.07 14.17 13.53
TYVPKEFNAET 16.69 16.72 18.40 15.81 15.73 14.13 15.25 12.18 15.18 14.25 15.63 14.13 13.93 13.38 15.83 14.51 9.92 12.30 15.98 13.11 14.85 15.31 10.54 13.28 11.60 13.78 14.87 13.79 14.54 14.95 16.94 15.14 16.50 12.18 14.94 14.36 14.89 13.76 15.34 15.60 15.45 13.59 16.87 15.97 14.16 15.81 10.76 14.94 17.04 15.47 14.54 13.41 14.87 12.81 14.86 13.94 16.24 15.80 13.60 15.88 12.92 11.61 13.49 16.92 13.54 11.07 14.97 11.45 14.17 10.59 10.76 14.24 15.46 15.63 15.50 11.16 15.61 13.24 16.84 16.55 13.58 15.62 16.79 12.67 15.35 16.27 12.91
EETLTHTITKL 18.47 15.55 17.62 14.49 12.42 14.44 14.26 13.36 15.48 13.75 18.35 14.47 14.39 14.26 16.87 15.63 12.29 13.78 14.26 14.51 15.35 13.72 14.54 12.61 13.06 14.55 14.66 13.48 12.26 16.44 16.23 17.39 14.73 13.49 14.11 13.05 15.68 15.96 15.72 15.81 16.47 15.76 19.81 14.14 15.05 20.20 12.46 15.14 14.16 19.50 16.51 15.96 17.47 16.95 15.15 15.39 15.11 16.64 14.94 16.21 13.90 11.27 13.41 14.77 14.05 11.68 12.97 11.07 16.83 15.00 14.27 16.54 15.53 17.57 16.87 14.45 19.76 13.28 16.47 14.17 13.48 16.83 16.94 12.57 16.20 18.87 16.04
LSDPDKVTIGLL 17.10 15.86 16.01 14.56 14.17 13.86 15.11 13.63 15.05 13.92 17.13 13.75 14.50 13.78 15.11 15.74 14.70 11.36 16.46 14.87 12.04 12.99 14.33 13.33 11.45 12.84 13.66 11.83 14.28 17.57 17.44 17.06 17.05 13.61 12.53 13.07 10.19 15.95 17.03 17.65 15.91 14.52 17.67 9.98 13.73 17.63 16.23 15.10 15.17 17.56 15.23 15.33 15.85 14.64 15.81 15.49 13.69 15.11 14.33 16.58 15.04 12.92 10.21 16.00 13.91 13.22 10.53 9.65 16.61 14.46 12.33 15.72 15.43 13.96 14.33 15.66 17.08 13.27 14.88 11.17 12.99 13.33 17.83 9.91 16.23 17.04 15.33
ASWDVEKTAIF 15.40 13.54 16.05 12.72 7.92 11.72 14.16 11.06 13.81 13.10 14.76 12.83 12.43 13.28 13.94 11.93 10.53 10.85 14.89 12.46 11.24 11.64 12.21 11.85 11.47 12.90 11.85 12.48 14.37 14.04 15.23 14.49 14.28 13.18 11.82 11.71 10.52 13.48 14.81 13.19 13.94 13.36 12.57 8.77 12.87 16.06 11.88 13.37 14.26 15.91 13.93 14.41 16.62 13.22 13.68 12.57 13.34 15.23 16.93 13.75 13.65 10.88 13.04 13.79 11.12 13.08 13.70 11.53 13.25 9.70 9.79 14.02 12.22 12.89 12.99 11.26 15.42 11.04 13.31 12.07 12.16 12.83 14.28 9.86 14.09 14.75 13.09
LRVAPEEHPVL 16.50 14.12 18.23 11.33 13.05 14.14 11.60 11.01 12.42 16.66 15.49 12.66 12.99 12.37 17.31 14.46 12.33 10.60 15.33 12.82 14.28 14.86 11.47 9.82 8.87 14.75 12.25 9.73 14.72 16.91 12.35 16.44 14.65 12.44 10.70 11.83 13.04 15.56 14.79 15.49 16.11 13.62 18.01 12.27 12.57 16.97 13.73 10.43 18.14 16.24 16.32 14.21 16.97 17.06 14.64 11.60 15.90 14.99 16.00 16.52 14.59 9.22 13.16 16.52 12.35 10.76 15.10 12.42 13.65 10.91 9.92 15.67 16.09 17.83 14.79 12.42 17.84 11.31 12.93 14.99 14.29 15.84 16.81 14.12 15.83 16.03 16.67
IVLWQPVTADL 14.28 14.00 17.86 13.08 10.81 12.19 12.88 10.99 15.22 13.23 14.91 12.52 11.95 13.96 14.22 11.97 11.99 10.62 15.21 13.37 13.34 14.25 13.03 12.83 11.56 13.88 12.95 10.85 13.01 13.75 13.93 12.96 13.83 10.44 11.75 12.12 12.45 13.36 14.75 14.15 13.64 12.71 14.28 11.36 12.52 14.99 12.10 10.92 14.95 15.08 14.75 13.65 15.31 13.15 14.33 12.50 13.88 15.04 14.06 14.72 14.14 12.22 13.78 13.74 11.12 13.50 13.04 12.65 14.31 12.20 14.42 15.21 12.77 12.98 10.62 17.13 14.65 11.72 12.39 11.99 10.11 13.28 13.88 12.01 13.20 13.89 14.50
DGVPGKDGPRGPT 16.61 15.72 18.54 15.67 15.06 15.27 15.89 14.68 16.81 15.25 16.06 14.76 14.87 15.45 16.23 16.68 14.47 14.56 17.86 17.74 17.84 17.23 17.99 15.91 15.08 17.25 18.18 16.02 18.42 18.65 17.92 18.18 16.54 17.64 15.10 15.62 13.72 17.40 18.48 16.83 17.85 17.01 18.52 15.86 14.76 16.99 16.53 14.81 17.93 17.95 16.37 15.37 16.90 15.81 17.12 16.16 16.92 16.34 15.62 17.44 16.46 16.58 17.28 16.62 17.96 16.63 17.14 15.11 17.85 17.55 16.52 16.91 18.14 16.60 16.71 13.50 18.18 17.33 16.88 17.28 17.41 17.75 18.62 16.76 17.71 17.35 17.69
GRLASPGFPGEY 16.04 13.45 12.55 14.67 14.34 13.25 15.61 12.51 16.04 13.30 14.69 14.66 14.06 14.27 14.33 13.97 11.09 10.84 13.61 12.74 13.27 13.29 12.78 13.62 13.67 11.57 13.80 9.82 14.42 14.72 15.60 18.46 15.69 13.54 11.99 13.71 13.24 14.49 13.21 15.09 14.03 14.11 16.87 13.95 11.07 16.83 10.34 14.73 13.53 19.17 14.97 12.48 14.14 13.85 14.91 11.82 13.56 15.26 14.05 18.28 10.42 12.47 13.17 13.64 12.62 13.29 13.41 12.34 15.06 13.52 13.00 14.76 14.18 14.64 17.27 13.84 15.29 12.40 14.07 12.60 12.91 11.10 17.05 11.17 13.17 15.92 14.08
FKSLPGQNEDL 16.29 15.92 15.49 13.48 13.75 12.49 13.18 11.87 15.72 13.45 15.23 12.60 13.07 12.84 14.37 14.36 10.50 11.39 13.86 13.27 14.82 15.68 12.03 12.13 13.37 13.34 14.55 10.25 14.50 14.27 14.12 15.01 14.60 11.75 13.82 12.05 10.96 12.17 14.84 13.38 12.77 14.11 17.12 12.80 12.75 14.95 16.23 14.06 16.60 16.10 14.03 13.21 15.38 13.07 14.70 13.84 15.91 14.19 12.62 12.96 13.49 13.62 10.46 16.82 13.40 13.51 15.34 12.57 14.57 14.53 13.05 14.97 13.07 14.49 16.52 17.13 16.33 12.78 15.38 13.56 12.64 13.56 16.20 12.53 13.36 15.49 13.82
VIKGARDSHAGL 20.98 17.22 19.27 16.08 14.38 15.38 15.20 13.56 15.44 14.37 20.29 14.37 14.10 15.39 20.49 17.15 12.12 11.50 17.63 15.56 17.62 18.11 16.43 15.56 13.84 14.59 12.86 14.64 17.36 18.71 18.54 20.56 19.13 17.60 15.29 13.16 13.93 18.78 19.03 20.32 17.78 17.76 21.00 14.69 13.75 21.95 14.95 17.90 20.48 20.96 19.89 17.87 17.14 20.10 20.05 14.04 15.41 16.27 15.55 18.41 16.47 12.58 11.68 17.06 16.82 11.23 15.97 13.93 18.48 16.12 14.69 20.94 19.13 20.25 18.38 17.65 20.11 14.67 17.35 12.41 16.71 19.90 19.64 15.80 17.33 18.39 19.07
DDEKNWGLSF 14.74 13.02 14.54 12.11 13.65 12.34 13.52 14.43 13.88 13.79 14.91 13.76 13.98 13.65 15.06 14.82 11.14 8.60 12.96 14.28 14.79 15.73 13.83 12.13 12.36 12.12 14.58 12.96 13.49 14.60 17.28 15.88 16.23 11.78 14.13 10.56 12.72 13.89 15.14 14.21 12.68 12.47 17.47 11.44 10.62 15.08 10.34 14.38 14.27 16.86 14.72 12.99 13.96 14.01 14.41 13.42 13.13 13.60 14.40 14.55 12.93 11.44 13.21 13.79 13.24 13.24 14.61 12.52 13.71 14.82 11.43 15.09 14.16 11.86 15.16 11.65 13.79 11.54 14.30 12.69 12.45 11.62 13.47 12.16 12.40 15.65 13.42
YEKTDTDGKF 16.25 15.71 16.29 16.24 16.96 15.66 15.66 12.73 16.13 13.99 16.10 15.46 15.75 15.42 14.91 13.39 11.14 9.76 13.89 12.64 11.87 15.56 13.91 14.50 13.81 12.00 14.75 10.07 13.57 13.39 16.87 17.90 13.13 15.97 14.82 13.42 16.14 15.33 14.11 15.22 12.32 15.43 17.71 14.91 13.36 17.72 16.23 16.29 15.44 18.30 11.68 15.86 14.87 13.66 14.25 13.99 13.08 14.59 14.04 15.66 13.97 13.50 11.48 13.92 12.72 12.11 12.34 13.28 15.01 12.76 12.76 16.90 14.52 13.88 16.85 13.84 16.71 14.08 16.57 13.95 14.24 14.01 15.35 13.70 12.86 15.16 15.37
ISWDGLDSGKL 15.19 12.57 14.66 11.79 9.84 11.67 13.45 11.31 13.84 12.99 13.88 12.40 13.49 12.74 11.31 13.66 11.25 11.31 12.09 11.63 12.75 10.23 11.10 11.74 11.39 12.15 12.35 8.55 11.91 13.01 13.13 13.34 12.08 12.39 12.39 12.12 9.97 12.05 12.80 12.63 12.44 11.51 15.43 12.43 8.82 14.78 10.34 12.61 14.36 14.58 11.66 13.52 13.96 14.74 13.22 12.63 12.77 13.85 14.05 12.75 12.45 10.06 10.85 12.78 11.99 10.96 11.76 10.87 12.56 12.26 12.18 12.15 11.20 12.92 12.30 11.26 14.50 11.68 12.30 11.53 9.98 10.70 12.51 10.95 12.30 12.77 11.48
WRQVEGM(+15.99)ED 14.49 13.98 18.06 14.26 15.76 12.71 13.13 12.26 14.07 11.35 15.39 12.71 9.37 13.79 13.17 12.86 11.09 5.69 13.51 15.46 14.40 14.28 10.35 11.94 12.31 7.86 10.80 13.58 15.25 15.12 15.95 16.86 15.31 13.60 14.13 12.84 15.10 13.86 14.36 15.12 13.00 12.03 15.71 13.89 12.35 12.66 12.24 13.26 16.31 15.81 13.38 14.04 14.38 11.40 12.43 12.78 12.50 13.76 11.62 14.82 13.87 13.29 8.98 13.06 13.27 13.57 14.70 12.08 14.34 13.58 13.10 14.98 12.91 15.72 13.41 17.13 15.03 12.97 14.42 14.77 13.72 11.38 15.04 13.24 13.74 14.19 11.13
KTALQPMVSAL 15.80 12.80 17.05 11.64 9.66 10.59 14.03 10.19 12.60 13.27 15.11 13.15 13.03 12.52 13.92 13.50 10.59 9.67 11.69 14.37 11.87 12.99 12.89 10.62 11.33 12.08 9.71 11.68 13.23 15.50 12.84 13.44 13.52 11.95 10.49 12.53 11.30 9.77 12.69 13.93 13.02 13.25 14.46 10.36 11.75 16.20 10.34 13.21 14.48 16.65 11.01 14.63 15.36 14.22 14.44 13.54 12.94 14.20 14.20 14.47 13.63 8.89 12.34 15.38 9.83 11.82 10.80 11.52 13.93 12.23 9.61 11.63 10.30 11.70 14.30 12.74 14.31 11.69 13.50 11.13 12.11 12.31 11.65 11.72 12.75 15.19 11.39
WRQVEGMED 16.35 15.01 14.73 13.68 16.17 13.65 14.23 10.00 14.41 13.83 15.97 14.09 13.09 14.33 15.01 14.71 11.09 12.50 13.63 14.94 15.24 12.63 10.39 14.21 14.09 12.65 9.30 12.32 9.04 14.72 17.61 18.64 17.23 15.20 14.75 12.48 15.63 14.46 14.21 14.39 14.62 14.04 17.01 14.09 13.01 15.24 14.01 14.94 15.76 16.32 14.96 13.84 15.08 14.98 9.35 13.06 14.27 14.82 12.76 15.21 16.03 10.15 13.28 13.95 10.96 12.74 14.43 12.25 14.57 7.51 13.82 16.09 14.76 14.48 15.29 14.94 16.07 13.46 14.97 16.49 14.02 12.42 14.42 12.27 12.87 15.37 13.84
YVVHTNYDE 14.07 15.34 15.27 15.47 15.38 13.58 13.80 12.93 14.37 12.77 17.44 13.51 13.93 13.15 14.59 14.04 11.78 10.29 14.48 12.84 14.07 12.91 11.59 10.18 13.88 14.08 11.88 8.49 15.02 15.50 16.72 17.02 16.45 14.66 14.36 12.76 15.36 15.55 15.74 15.43 13.05 14.69 16.80 14.16 13.26 14.72 11.73 15.31 13.66 16.13 14.00 13.55 15.44 12.79 13.81 14.63 13.42 15.29 10.07 16.41 14.86 13.42 12.15 12.41 13.41 12.73 12.31 13.03 15.46 12.83 13.65 16.92 14.26 13.96 15.60 14.29 15.21 15.35 16.07 13.92 14.08 14.05 15.59 12.87 14.36 15.78 14.45
PGKDGPRGPTGP 18.55 17.49 19.93 18.70 17.90 19.47 17.87 16.42 19.30 17.97 18.01 18.22 16.63 18.43 17.57 16.97 13.31 15.59 15.52 15.41 15.11 15.04 15.60 15.50 16.45 17.98 15.80 15.31 18.67 16.03 15.40 15.42 15.34 14.92 15.10 18.08 15.81 14.89 16.35 16.54 15.45 14.72 16.53 16.01 17.78 18.48 15.14 18.37 19.17 18.93 18.37 17.03 17.76 17.76 17.75 18.33 17.93 19.68 15.86 19.06 18.21 13.90 14.65 15.58 15.41 14.68 15.53 12.02 15.37 15.62 16.31 15.77 15.83 16.30 16.69 15.59 16.12 16.12 14.55 17.70 14.95 16.11 15.74 15.14 14.74 16.56 16.44
VQVFAPANALP 11.47 13.92 15.04 13.26 9.84 12.39 13.93 11.31 13.64 12.79 14.65 12.40 14.36 13.05 14.79 13.76 11.23 11.86 12.86 12.86 10.90 13.73 11.64 12.44 12.32 13.55 10.88 11.06 13.89 13.54 14.35 13.30 12.60 12.92 13.28 12.12 14.26 13.01 13.93 12.21 13.82 12.18 15.02 12.82 13.10 14.84 10.34 13.50 14.71 12.95 13.22 13.54 13.62 14.17 13.99 12.52 12.53 13.89 13.54 10.10 12.51 13.36 11.75 13.26 12.70 11.84 11.70 12.07 12.72 10.00 11.45 13.58 11.46 12.53 13.36 13.50 13.74 12.46 14.17 12.71 13.94 12.26 13.18 13.23 12.74 13.86 11.80
HQDWLNGKE 13.12 12.77 15.85 12.82 11.23 14.09 13.29 9.52 13.27 13.65 16.07 12.04 12.57 12.98 14.11 11.37 12.21 12.57 13.61 12.14 13.97 13.76 12.65 12.05 13.02 14.99 13.04 12.94 15.21 14.26 13.94 15.16 9.08 12.78 11.59 14.53 11.82 12.78 15.35 13.75 15.19 13.36 17.15 13.03 13.21 14.64 12.97 14.15 14.26 15.66 13.15 10.25 14.25 11.02 14.04 12.36 13.77 14.56 12.82 15.55 14.10 13.16 14.43 11.62 13.86 13.32 14.12 12.46 13.91 13.81 12.73 13.14 12.51 15.29 12.17 11.26 15.39 13.24 13.18 11.91 13.56 14.28 13.65 15.34 12.82 12.19 14.90
ASWDVEKTAI 15.64 14.37 15.85 12.72 11.12 11.69 13.22 11.46 13.32 14.85 14.82 12.85 11.61 12.23 14.18 14.38 10.46 9.33 13.30 11.24 13.30 15.34 11.31 10.46 10.92 12.94 13.81 13.11 14.59 13.87 15.83 15.24 14.89 13.80 10.42 10.67 12.34 13.29 15.64 14.42 14.16 13.98 15.64 11.16 12.67 14.37 11.42 12.32 12.91 16.18 13.52 12.60 15.38 13.35 13.49 14.14 13.69 13.88 13.21 13.57 12.92 9.84 11.60 14.47 16.99 13.29 14.19 10.18 12.35 14.61 10.49 14.10 13.58 13.47 14.23 17.13 14.73 10.96 15.41 12.45 13.53 12.87 15.12 11.38 13.58 14.85 13.16
YKAIPVAQDL 14.22 13.96 15.09 14.40 13.64 13.71 15.25 13.24 13.25 13.11 15.26 12.96 14.91 12.78 14.97 14.43 7.26 13.37 12.21 14.52 14.80 15.71 13.61 11.92 12.37 11.07 14.35 10.05 13.36 10.93 13.25 13.86 12.93 10.42 11.80 11.36 12.45 13.01 13.39 12.24 13.03 12.73 13.47 12.43 14.41 13.64 16.23 16.32 14.79 15.41 14.78 12.50 14.79 13.27 14.63 14.67 13.92 12.48 14.16 12.45 12.04 14.48 11.02 13.66 13.11 10.16 14.91 12.45 13.69 14.93 9.57 13.93 13.01 12.95 14.98 11.47 15.17 12.16 14.99 10.98 12.34 13.22 11.61 8.88 13.56 15.89 12.98
RAHGQESAIF 19.49 15.05 10.16 14.05 14.24 14.98 14.77 12.90 14.56 12.53 18.18 14.69 14.59 15.99 18.27 17.65 13.44 12.20 16.90 15.30 16.97 17.02 15.49 14.64 13.61 13.29 16.08 7.93 16.52 18.02 17.95 19.56 18.51 16.55 13.41 14.12 13.23 18.33 18.07 19.41 16.93 15.43 19.15 13.66 12.51 20.20 11.74 15.73 19.36 18.57 18.31 17.86 17.85 18.15 17.92 14.84 15.36 16.69 15.44 18.58 15.72 12.35 15.61 16.95 15.51 11.60 12.30 12.58 17.01 14.58 12.84 19.31 17.50 18.39 16.81 16.74 19.13 14.24 16.43 14.93 15.46 17.95 17.15 14.48 16.05 17.23 17.99
FRFAGNYDL 16.20 12.63 15.71 13.44 9.52 11.59 11.44 10.17 12.87 12.25 14.89 9.28 9.13 13.18 14.38 14.02 10.16 10.80 12.02 11.95 10.44 12.83 13.52 11.91 10.83 13.40 11.48 11.91 14.01 15.62 14.11 14.98 14.47 12.03 10.11 11.45 10.84 11.17 14.62 14.96 12.89 12.70 13.98 9.77 12.38 16.87 12.64 12.00 11.06 17.13 14.31 14.88 16.01 14.54 12.76 9.38 12.95 14.37 11.94 14.10 12.26 10.45 11.73 11.98 10.47 9.23 13.76 10.26 13.95 9.22 13.15 14.74 12.58 12.19 14.65 13.94 15.35 11.25 13.50 10.50 11.42 12.47 13.77 9.29 13.87 16.26 13.17
FSSPHGKDLL 19.91 15.61 20.07 13.55 14.16 10.36 12.11 9.52 14.73 13.48 17.34 12.62 12.01 14.50 19.24 15.97 12.51 12.21 18.79 13.98 17.49 13.53 10.58 8.72 11.15 14.33 14.00 12.75 14.49 15.84 17.74 18.00 17.48 11.50 13.87 12.79 12.36 15.48 17.02 17.31 17.39 13.90 19.55 13.27 12.70 18.19 12.24 13.18 19.58 17.80 16.62 15.11 16.96 15.07 17.19 12.84 17.41 17.58 16.08 18.28 14.15 13.52 13.65 19.60 14.17 13.48 13.86 12.09 16.74 12.08 7.82 16.85 16.40 17.45 16.92 12.90 18.21 11.59 16.23 15.52 11.47 16.05 18.84 11.68 17.36 17.84 16.04
PILRHGIQY 19.16 13.30 15.42 12.64 14.06 10.92 13.43 9.86 13.75 10.91 14.31 14.00 13.18 13.48 11.51 16.76 11.93 11.23 13.33 15.04 14.63 15.94 13.53 13.01 12.64 10.86 14.39 13.62 13.55 14.46 12.53 15.08 14.11 13.05 12.14 11.29 11.91 14.01 11.01 13.48 12.12 12.31 18.16 11.93 9.53 19.60 12.46 15.12 16.12 18.52 15.06 16.83 16.01 17.17 15.74 13.41 13.63 14.43 11.47 16.65 14.03 10.22 13.20 15.05 13.90 14.20 15.56 12.68 10.95 15.16 14.20 14.79 15.50 17.66 15.11 15.39 16.76 13.06 13.17 12.59 12.49 12.34 14.21 10.85 12.73 15.25 11.82
AVRLVFQDF 15.72 12.63 15.35 13.29 8.63 11.49 13.99 10.61 12.90 13.96 15.45 13.53 11.79 13.37 14.56 14.62 9.98 10.15 15.24 12.65 14.66 15.03 13.38 13.02 10.77 13.03 11.67 12.61 11.92 12.67 13.05 12.49 11.89 12.10 10.03 11.55 10.41 12.35 13.33 13.38 13.07 12.05 14.30 11.29 12.54 16.27 11.56 13.34 15.86 15.63 16.33 14.19 15.84 13.86 15.51 13.43 13.78 14.83 14.83 16.07 14.08 10.89 11.59 13.87 12.52 11.06 11.82 11.00 14.28 13.12 12.37 12.77 13.23 12.97 12.52 11.34 14.09 10.60 12.21 12.18 10.40 12.77 13.11 9.37 12.39 12.00 13.04
GRLASPGFPGE 15.06 13.73 17.77 13.76 14.37 12.55 13.03 11.53 15.72 13.59 14.83 12.31 13.57 12.33 14.03 13.98 11.83 11.03 12.91 13.22 11.68 14.98 13.44 12.52 13.82 10.88 14.43 13.49 12.06 13.90 13.59 16.24 13.90 12.60 13.79 13.68 14.50 12.01 14.38 15.43 13.63 13.64 16.02 13.00 12.57 16.49 13.67 13.91 17.17 17.51 14.05 14.08 18.44 13.82 15.19 14.45 14.29 15.00 13.30 17.13 14.04 13.18 13.37 13.89 10.54 14.84 12.98 12.67 15.01 14.77 10.75 12.88 12.89 14.14 17.59 17.13 15.82 11.25 14.63 14.27 11.80 13.48 16.14 13.21 12.87 14.59 12.81
GPKWPEPVF 16.55 13.33 16.02 13.86 8.71 12.91 13.40 11.07 15.58 13.02 17.68 12.71 13.14 13.50 15.26 13.04 10.93 10.97 14.56 14.80 15.38 15.11 14.26 12.08 12.10 13.91 13.02 11.00 14.30 15.52 16.78 15.65 15.70 12.61 9.94 12.90 13.40 16.16 16.23 16.80 14.05 11.79 14.33 12.96 11.83 16.51 13.00 15.03 15.18 18.43 15.09 16.33 16.31 14.29 7.95 12.73 13.18 15.63 16.93 18.73 13.24 11.66 12.99 13.99 13.89 12.58 12.85 11.34 14.45 15.58 13.95 17.08 14.61 14.79 14.02 13.09 14.96 13.68 13.54 13.26 12.66 12.34 15.77 13.34 15.49 14.12 13.81
IVDKVKPQL 15.20 16.17 15.75 14.70 14.79 13.89 14.16 13.12 17.64 13.64 11.93 12.55 14.58 14.07 14.65 8.66 11.21 11.40 14.57 14.51 14.90 15.67 11.13 13.85 14.64 14.14 14.37 10.74 16.12 14.72 15.24 16.21 14.19 13.75 15.37 14.80 10.65 12.31 14.93 12.02 13.33 15.10 18.58 11.17 14.55 15.41 9.62 15.21 13.53 17.19 14.94 12.24 14.87 13.01 12.93 15.65 15.56 14.45 12.56 16.70 13.34 15.17 11.78 12.20 12.76 14.58 12.18 13.25 14.81 14.59 9.25 15.60 14.80 13.48 17.81 11.61 16.67 11.15 15.91 15.04 11.58 14.85 15.37 14.46 12.72 16.35 13.43
VVLPKHILD 15.03 11.28 18.79 13.54 11.33 12.28 12.48 10.84 15.88 12.79 16.78 9.38 12.69 11.76 15.11 14.27 11.59 10.79 10.93 14.23 12.10 12.68 13.84 11.94 11.73 12.39 9.57 12.76 12.84 12.75 13.02 13.26 12.96 12.47 11.96 12.17 12.42 12.96 15.09 13.39 12.41 12.49 13.37 12.15 12.33 16.38 12.64 13.48 13.85 15.32 15.36 13.94 15.51 13.39 16.01 13.28 13.21 13.71 9.91 15.13 11.85 12.23 12.08 13.23 13.68 12.58 13.87 11.47 12.71 11.78 10.41 14.88 12.76 12.09 12.39 13.47 14.17 12.29 11.32 12.90 10.37 10.13 13.10 9.14 11.96 13.60 12.65
NVAKGIRSF 17.39 13.26 15.78 13.49 12.83 12.14 13.42 10.63 14.16 16.47 17.15 12.54 12.02 14.10 18.84 15.25 9.99 10.37 14.22 13.34 13.26 14.13 13.48 11.93 12.35 12.45 13.27 12.71 15.09 13.53 15.97 14.95 14.56 12.24 13.52 11.26 13.10 15.35 16.35 15.59 14.74 11.47 15.69 12.70 11.76 17.50 13.29 14.52 17.08 17.61 16.85 15.74 17.25 15.79 15.85 13.25 14.46 14.18 16.93 15.97 13.44 12.33 12.94 15.14 15.55 13.56 14.57 11.48 12.63 13.30 13.96 16.48 16.23 15.75 13.30 15.53 15.72 12.87 14.16 12.36 13.11 14.08 15.29 10.89 15.06 15.17 14.82
VLNLGPITR 15.37 16.45 16.17 15.18 13.59 14.36 16.05 12.93 15.82 15.33 16.48 15.63 14.71 14.73 16.63 15.38 14.12 14.47 16.01 15.79 16.24 16.18 14.03 12.39 14.09 15.88 16.86 15.30 15.42 15.60 16.12 14.54 14.74 13.23 12.21 13.38 13.77 16.21 15.92 15.64 15.92 14.26 13.68 13.04 15.17 16.08 15.46 16.27 14.60 16.92 16.38 13.99 16.73 13.61 16.31 16.36 16.29 16.64 13.78 17.51 16.00 15.02 16.37 16.20 15.15 14.76 15.69 14.71 15.73 15.77 16.00 15.56 16.78 14.67 13.77 12.51 15.71 15.38 15.02 15.55 15.53 15.95 15.88 13.44 15.86 17.03 14.49
PGKDGPRGPT 17.39 16.06 18.23 16.45 14.61 16.62 16.93 14.76 16.90 16.80 17.68 16.09 15.10 15.78 17.54 18.00 13.81 13.22 17.13 17.24 16.50 15.98 16.66 14.97 14.62 16.32 17.34 15.20 16.93 17.40 16.81 17.07 16.23 16.65 14.20 15.10 13.46 16.51 17.52 16.96 17.11 16.13 17.84 15.41 15.82 18.54 18.13 15.49 18.23 18.08 17.60 15.64 18.45 16.32 17.87 16.39 16.93 16.76 16.41 18.35 15.28 15.71 16.27 15.69 16.53 15.71 16.14 14.45 16.86 16.77 15.52 16.85 17.37 16.48 16.27 14.76 17.22 16.32 16.04 16.38 16.39 17.60 17.38 15.82 16.63 16.44 17.64
KELKFVTL 16.51 13.53 16.02 13.60 12.92 12.52 14.43 10.35 12.13 12.01 11.66 12.43 12.79 12.80 17.13 15.90 11.99 11.42 13.80 12.92 14.56 14.89 11.73 12.15 12.63 10.13 10.14 13.21 13.83 14.23 14.70 14.49 13.76 11.70 10.76 12.83 12.16 12.96 12.97 13.78 13.62 12.82 15.83 12.33 12.60 17.17 12.01 13.51 17.42 15.74 16.79 14.83 15.24 15.00 14.55 11.92 12.83 15.72 13.17 16.94 12.56 12.95 13.15 11.61 13.59 13.30 12.35 12.30 12.93 12.58 13.64 11.36 12.88 13.39 12.23 12.77 13.86 13.03 13.84 12.63 12.75 14.80 13.45 13.68 11.84 12.98 13.54
SKWSGPLSL 15.29 12.86 13.63 11.88 9.36 11.80 11.05 11.16 11.32 12.99 13.02 12.40 13.40 12.23 14.24 13.23 10.41 11.05 11.92 11.49 12.41 12.04 11.74 11.82 10.97 11.66 11.17 10.55 10.31 12.57 13.43 12.26 10.51 12.35 12.34 11.21 13.33 10.75 13.60 12.77 12.36 11.44 13.58 12.82 12.17 15.14 10.24 12.35 13.65 14.24 13.77 12.47 13.88 14.06 13.66 11.98 10.95 13.84 14.05 12.29 11.78 11.35 8.74 12.39 11.99 11.27 12.07 11.50 12.36 11.05 11.68 13.43 11.96 14.15 11.57 17.13 14.02 11.06 12.64 7.28 12.16 11.82 12.00 12.07 10.06 12.60 11.50
YKWKETL 17.52 14.49 15.86 13.70 16.96 14.70 14.86 13.21 15.74 15.20 17.65 14.60 14.36 12.62 15.86 14.91 12.52 9.62 12.08 13.26 13.79 9.91 13.40 13.26 12.60 13.56 14.33 13.08 13.29 13.13 13.89 16.44 13.97 14.10 13.43 11.67 14.65 14.30 15.70 16.26 13.06 14.28 18.72 13.15 13.36 18.71 17.09 14.16 17.29 18.67 15.45 16.56 17.41 17.11 15.98 14.99 14.68 15.16 14.12 18.11 14.11 12.34 12.64 11.80 12.98 13.21 14.66 12.65 14.27 14.09 12.92 16.50 14.10 16.23 14.13 16.78 16.70 13.26 14.98 12.67 12.79 15.14 15.75 12.77 14.86 14.57 14.13
PRYPVGKF 20.95 17.65 16.74 16.85 16.98 16.18 17.36 13.49 17.27 14.67 19.07 17.12 17.15 15.85 19.26 18.48 12.39 11.85 14.42 13.03 12.01 13.43 13.40 10.98 12.40 11.47 14.56 10.63 16.40 15.93 15.86 16.72 15.78 11.95 15.04 13.33 15.28 15.27 15.51 15.80 14.92 12.38 17.59 13.30 15.22 21.18 15.20 18.32 19.19 21.06 19.38 19.54 20.53 19.28 19.45 15.63 17.18 18.07 15.60 19.52 12.18 13.71 11.09 13.21 14.77 10.59 15.24 10.81 11.54 11.07 10.69 17.25 15.49 16.96 16.55 15.42 16.57 13.85 15.99 12.28 14.97 16.17 16.91 13.73 15.90 18.03 14.56
RPPGFSPF 16.65 13.96 16.38 14.21 12.31 13.68 14.80 8.31 13.95 14.57 15.32 14.68 13.64 15.30 16.05 14.92 11.71 10.28 14.76 13.74 15.85 14.12 11.80 12.10 12.76 13.13 14.39 13.29 13.68 15.00 14.88 13.91 15.71 12.34 13.07 10.86 13.05 13.26 14.35 14.27 13.65 12.89 13.81 12.37 13.66 16.71 14.73 13.64 15.20 14.41 17.03 13.34 15.36 16.05 15.09 14.34 14.44 15.97 13.99 16.14 15.12 12.26 12.92 9.50 12.94 13.74 15.98 12.14 15.32 10.07 13.61 15.26 14.01 14.98 13.01 12.72 15.11 13.51 13.54 13.22 13.83 12.35 15.17 13.11 12.87 14.42 13.80
LNLGPITR 18.16 17.42 16.65 15.36 16.33 15.85 15.17 14.86 15.22 14.16 16.62 15.12 16.35 14.44 16.71 15.89 12.52 15.59 15.82 15.09 14.54 15.69 14.70 12.95 14.51 15.00 13.83 12.32 16.85 18.14 16.77 17.98 16.82 14.58 15.61 14.78 17.18 16.27 17.57 16.07 17.18 16.96 18.40 15.62 16.37 18.79 14.31 18.67 17.07 18.80 16.36 14.92 17.52 16.35 17.17 14.82 15.84 16.46 14.74 17.67 15.57 15.79 13.96 15.97 14.97 13.55 12.97 14.10 17.19 13.45 13.74 18.25 17.08 18.08 16.41 13.53 19.82 14.88 18.16 14.70 17.24 17.04 17.48 14.48 16.65 19.44 16.50
FTVRMAL 14.68 13.31 14.90 14.35 12.79 11.65 13.35 10.14 13.02 12.89 13.84 12.42 11.85 13.43 15.54 14.56 10.16 10.04 12.46 14.82 12.90 13.94 14.16 12.76 12.46 13.31 13.98 12.63 15.04 17.18 13.74 14.90 15.96 12.39 13.76 11.45 13.31 13.03 14.17 15.67 15.26 14.46 14.80 12.33 12.81 16.18 11.91 13.77 15.17 17.58 13.83 14.10 15.14 12.98 13.96 12.88 13.64 15.15 13.94 15.57 15.49 11.48 13.01 13.80 12.91 13.10 14.54 11.68 14.84 11.82 14.02 13.81 14.15 13.50 15.36 11.65 16.24 13.02 15.18 12.95 12.98 13.38 13.70 13.04 13.71 16.44 13.84
MGPPGNPGP 18.42 17.05 16.58 17.56 14.54 16.97 16.59 14.69 16.70 10.36 19.00 15.53 15.75 16.93 17.68 17.90 13.45 12.41 18.54 12.03 16.72 16.77 16.51 14.65 13.07 14.92 16.00 13.29 16.78 18.85 17.36 17.71 16.62 16.11 13.77 15.59 13.39 13.38 17.27 19.65 18.67 15.50 16.75 14.12 15.56 17.50 16.59 15.83 18.19 19.20 18.49 17.02 17.79 18.81 17.88 15.82 15.95 17.61 15.60 17.91 15.27 16.11 15.32 16.12 16.40 15.21 14.08 12.03 16.44 16.17 13.99 18.82 18.83 20.12 17.49 18.24 19.12 15.76 16.45 15.29 17.83 17.85 16.52 17.53 16.28 13.86 19.84
HASLDKF 17.17 13.75 18.01 13.32 11.39 13.60 10.14 13.67 12.94 11.27 13.55 12.11 8.70 12.02 14.05 14.07 11.23 11.75 14.91 13.76 14.12 14.34 14.73 13.05 13.34 14.06 14.09 13.06 15.19 15.52 15.14 14.48 14.95 14.03 14.25 12.33 12.91 14.16 15.50 10.04 17.24 15.43 15.71 13.37 12.08 16.49 9.23 9.76 16.30 13.16 13.97 15.31 15.27 13.35 14.25 14.90 15.34 14.46 14.27 14.79 14.61 14.66 13.73 17.76 14.72 14.49 15.00 12.92 14.37 13.65 13.98 14.49 14.73 13.92 14.36 14.39 15.32 11.84 14.45 14.49 15.38 14.87 14.98 13.99 14.89 16.01 15.27
FESFGDL 14.87 9.39 13.67 10.67 8.63 10.81 13.14 11.00 11.23 12.22 10.52 12.88 9.32 10.68 13.57 13.49 8.32 9.04 12.99 13.81 12.89 9.80 9.26 10.66 11.22 12.96 7.81 10.21 10.55 11.75 13.15 11.09 10.77 12.66 8.77 8.14 12.89 12.06 13.03 10.27 10.85 11.03 12.69 12.43 12.17 15.54 10.13 11.33 14.40 15.16 13.75 11.05 14.17 14.21 11.37 11.14 12.52 9.79 16.93 13.43 9.30 8.58 11.84 13.85 12.82 10.34 10.57 11.22 11.34 9.04 10.02 12.62 9.12 10.03 10.76 11.26 13.55 12.46 10.33 12.04 9.04 12.22 15.38 12.70 10.38 9.15 9.38
PPPPPPPP 12.71 14.85 18.06 13.83 13.17 11.85 13.68 12.18 13.70 10.85 15.32 11.87 13.09 13.31 11.75 13.67 10.70 13.25 14.66 13.50 14.86 15.22 14.32 14.35 13.37 14.90 14.98 14.20 15.52 15.09 15.81 15.95 14.13 13.82 13.70 14.02 13.28 15.10 15.20 14.68 14.95 14.17 16.09 12.96 12.68 13.36 11.89 11.50 17.98 14.59 13.03 13.11 14.77 13.68 14.83 12.18 14.24 14.14 11.62 16.19 15.06 13.97 14.70 14.22 14.29 15.13 15.21 13.28 14.37 14.45 13.58 15.32 10.16 15.72 15.52 17.13 15.76 14.07 14.13 15.00 15.05 14.88 14.84 14.50 15.58 15.88 15.41
KLGHPDT 13.16 15.21 20.27 13.69 12.05 12.86 12.96 8.01 17.23 12.41 16.13 11.56 11.34 12.72 14.26 13.85 12.49 7.72 12.40 12.56 12.89 10.51 11.73 10.28 11.61 11.28 12.02 11.78 13.29 13.42 12.26 12.95 12.95 12.74 11.54 12.75 10.90 11.21 14.40 13.44 12.70 12.12 11.85 11.33 12.04 15.57 11.71 12.90 14.16 14.68 14.48 10.27 15.51 13.60 14.88 13.90 14.12 14.25 9.91 14.77 11.31 12.77 10.79 13.49 11.80 11.48 13.26 11.56 11.23 10.77 11.47 11.88 12.87 12.29 12.64 13.47 13.08 12.36 12.70 12.92 10.88 12.67 10.94 11.74 12.58 13.88 13.47
SDVFAAGT 16.79 16.30 16.29 12.48 13.73 16.41 16.10 12.26 17.54 15.48 16.84 11.22 13.69 16.70 17.90 17.49 16.70 12.47 16.33 16.08 15.98 16.25 13.44 14.19 10.95 14.73 13.12 15.04 15.33 17.23 11.72 17.82 15.86 14.45 13.97 13.83 14.90 15.39 16.00 18.92 17.38 17.56 15.22 11.42 15.47 11.76 17.22 15.65 17.44 15.65 17.94 15.38 12.77 17.11 15.28 12.93 16.47 16.12 15.52 16.04 13.22 13.84 13.97 13.71 16.84 14.97 15.87 15.93 14.85 13.42 14.95 13.87 17.09 18.17 15.56 16.01 13.50 16.98 16.95 10.20 14.60 14.55 17.31 10.97 15.62 14.48 15.66
APHGPGLI 14.74 13.47 13.45 13.04 14.06 13.48 9.89 9.52 14.23 13.65 14.59 11.57 12.55 12.66 14.85 13.16 12.39 12.40 9.54 14.01 12.55 14.31 12.45 11.14 13.25 11.39 13.52 12.96 13.78 13.87 14.23 16.63 14.00 14.52 12.20 12.94 13.51 12.74 14.33 13.97 13.20 13.47 16.55 12.16 13.21 15.41 12.97 13.18 11.85 10.39 13.43 14.88 14.10 13.21 13.96 11.33 14.02 13.94 12.87 15.77 12.82 12.68 13.52 12.88 12.68 11.60 11.27 11.84 14.11 11.63 11.11 14.51 13.12 14.19 14.51 12.22 16.31 12.77 13.69 12.63 12.76 13.27 15.06 9.24 12.81 13.65 13.22
PVVPVHL 14.46 14.40 14.78 14.03 13.00 12.95 13.42 11.39 14.22 13.17 12.59 14.42 12.96 14.80 14.36 12.71 10.47 12.16 12.81 11.84 9.95 7.65 12.54 13.72 12.52 12.59 11.45 9.10 14.99 13.33 15.79 13.75 12.38 12.49 13.33 12.51 14.19 14.52 13.76 13.59 14.23 14.34 14.99 11.38 13.35 13.36 10.34 14.33 12.30 14.73 12.55 13.52 13.37 11.90 13.79 15.62 11.90 13.93 12.60 14.61 10.61 14.84 13.60 13.05 9.83 14.03 12.33 14.98 12.10 10.18 11.11 12.69 15.08 12.05 14.59 15.00 14.74 12.75 16.31 13.57 11.71 13.84 11.99 13.49 13.21 14.97 11.67
KPALPAGT 15.25 10.54 14.19 13.47 9.36 11.68 13.58 10.82 12.06 13.79 15.19 13.37 10.36 11.33 15.26 13.10 8.56 10.69 14.52 14.68 14.32 13.28 15.16 11.80 12.16 12.20 12.13 11.24 12.81 11.90 13.53 11.07 12.35 12.36 11.46 11.71 12.53 12.65 11.10 11.33 12.93 10.78 14.18 12.00 12.75 16.98 11.56 13.38 15.06 13.28 16.35 14.71 15.42 14.74 13.95 14.80 13.04 12.86 14.85 15.25 12.27 12.11 12.86 12.73 11.55 10.48 11.86 11.69 13.82 12.70 12.22 12.88 11.19 11.64 13.03 13.54 12.79 8.83 12.67 12.33 12.44 12.19 13.77 12.23 11.83 12.82 11.72
APHGPGL 15.60 13.30 16.82 12.41 12.66 11.45 13.11 10.68 13.07 13.27 14.02 12.14 13.81 12.34 14.91 13.97 11.90 12.05 12.83 14.26 12.85 10.83 11.94 11.17 13.68 10.29 13.31 11.51 11.47 13.94 13.67 16.94 13.23 14.33 11.83 12.17 12.42 12.77 13.12 12.21 11.64 12.31 15.61 12.25 5.29 14.96 12.97 12.63 14.75 13.83 13.50 11.37 14.38 10.55 12.93 11.29 13.90 13.23 12.05 14.76 12.49 11.51 13.02 12.68 11.73 11.51 12.26 12.57 13.30 10.68 10.31 12.71 13.53 12.16 13.61 17.13 15.26 12.20 13.59 13.00 11.35 11.38 14.33 10.68 12.29 11.70 11.86
AGPSSPT 14.52 12.17 15.16 10.05 11.86 11.57 12.40 8.70 13.89 13.78 15.77 12.18 11.92 10.32 16.39 11.67 10.12 6.98 14.00 12.63 12.71 14.41 14.05 10.42 8.67 12.29 10.48 9.08 12.27 12.99 13.07 11.60 12.91 13.85 12.18 10.06 13.47 12.98 14.41 12.70 13.42 9.43 15.54 8.38 7.76 14.48 10.13 12.58 15.13 15.04 9.71 13.53 12.53 13.65 15.20 12.74 12.68 13.25 13.05 14.66 9.96 6.25 11.38 13.58 13.53 9.22 12.73 9.31 12.92 12.63 12.28 14.22 12.41 11.12 12.32 14.34 13.45 10.87 12.64 12.83 12.09 13.84 13.49 11.95 12.19 12.71 12.42

After imputation and log transformation, the data was normalized using EigenMS to account for sample-to-sample variability. EigenMS normalization preserves the treatment group differences in the data by estimating treatment effects with an ANOVA model, then uses singular value decomposition on the model residual matrix to identify and remove the bias.

Code
norm_d1 <- do_normalization_short(log2_d1, labels_d1)
hist_eigenms <- ggplot_truehist(unlist(norm_d1[-1,]), "log2-EigenMS")
qq_eigenms <- ggplot_carqq(unlist(norm_d1[-1,]), "log2-EigenMS")
pca_eigenms <- ggplot_pca(norm_d1[-1,], anno, "Label","log2-EigenMS")
Code
plot_grid(hist_eigenms, qq_eigenms, pca_eigenms, nrow = 1)

Code
norm_d1_mod = norm_d1[-1,] %>%
        as.data.frame() %>%
        rownames_to_column(., var = "rowname") %>%
        mutate(across(-rowname, as.numeric)) %>%
        column_to_rownames(., var = "rowname")
#write.csv(norm_d1_mod, file = "after_norm_data.csv")
# display table
norm_d1_mod %>% 
        mutate(across(everything(), round, digit=2)) %>%
        knitr::kable(., digits = 3, "html") %>%
        kableExtra::kable_styling(bootstrap_options = c("striped", "hover", "condensed", "responsive")) %>%
        kableExtra::scroll_box(width = "100%", height = "500px")
sample_1 sample_2 sample_3 sample_4 sample_5 sample_6 sample_7 sample_8 sample_17 sample_18 sample_19 sample_20 sample_21 sample_22 sample_23 sample_24 sample_33 sample_34 sample_35 sample_36 sample_37 sample_38 sample_39 sample_40 sample_49 sample_50 sample_51 sample_52 sample_56 sample_57 sample_58 sample_59 sample_60 sample_61 sample_62 sample_63 sample_72 sample_73 sample_74 sample_75 sample_76 sample_77 sample_78 sample_79 sample_9 sample_10 sample_11 sample_12 sample_13 sample_14 sample_15 sample_16 sample_25 sample_26 sample_27 sample_28 sample_29 sample_30 sample_31 sample_32 sample_41 sample_42 sample_43 sample_44 sample_45 sample_46 sample_47 sample_48 sample_53 sample_54 sample_55 sample_64 sample_65 sample_66 sample_67 sample_68 sample_69 sample_70 sample_71 sample_80 sample_81 sample_82 sample_83 sample_84 sample_85 sample_86 sample_87
FAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 15.33 14.82 14.79 13.34 17.29 14.43 17.07 15.94 17.48 16.18 15.28 16.80 15.93 16.09 15.80 16.56 15.50 15.17 14.16 15.35 14.57 14.43 15.49 16.78 16.34 15.72 14.94 16.23 16.42 15.15 15.32 15.62 16.05 16.61 13.56 12.86 15.32 14.38 14.33 16.30 15.57 16.52 12.97 12.58 16.04 17.46 14.77 15.88 14.61 17.87 15.76 17.22 16.12 15.73 17.40 14.79 16.71 16.08 16.12 16.18 15.43 15.88 16.41 15.97 16.72 18.00 17.66 17.30 16.67 15.93 16.84 17.27 17.23 16.21 17.45 16.53 16.88 17.32 16.89 15.10 16.00 16.49 15.60 17.42 15.96 15.04 16.39
EEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 16.98 17.81 15.78 16.51 15.95 17.41 18.04 17.66 16.74 17.92 16.68 18.48 17.22 16.80 18.34 18.40 11.95 17.60 18.54 18.15 17.36 17.10 17.89 18.60 17.30 18.10 16.68 17.39 18.63 17.06 16.58 16.03 17.08 17.95 17.80 17.43 18.68 16.46 16.84 18.55 17.81 18.28 16.92 18.47 19.18 18.49 17.46 18.89 17.85 18.36 18.13 18.32 18.92 17.78 18.82 17.93 18.17 18.80 19.10 17.92 18.21 17.88 17.05 18.99 17.85 18.37 17.09 19.69 18.60 17.76 16.36 17.62 18.73 17.63 18.85 18.74 18.54 19.06 19.10 17.69 18.93 19.12 17.60 19.16 18.38 18.33 18.42
DADLADGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 15.40 16.12 15.82 16.37 16.78 16.09 16.99 15.48 16.98 16.36 16.50 17.31 16.72 16.54 9.48 16.24 14.67 14.94 16.08 16.40 14.63 15.01 16.17 15.96 16.16 16.12 15.64 15.78 16.98 15.53 16.11 14.94 15.27 16.52 14.64 11.87 14.17 15.94 16.08 16.25 16.15 15.54 15.71 15.86 16.66 16.79 16.38 16.74 16.82 16.81 16.75 17.99 18.42 17.53 17.81 16.98 17.42 17.04 17.11 16.45 16.93 16.56 17.65 16.62 18.18 17.53 17.70 17.32 16.16 16.61 17.00 17.20 17.46 17.35 16.86 17.88 16.48 17.55 16.90 16.54 17.38 17.17 16.12 17.48 17.08 16.94 17.03
GRPEAQPPPLSSEHKEPVAGDAVPGPKDGSAPEVRGA 13.74 15.74 15.22 16.34 15.52 13.48 14.32 15.32 16.21 15.13 14.95 15.15 14.72 14.90 14.06 14.00 15.13 13.96 14.56 13.51 14.22 14.47 15.32 13.37 14.21 14.49 14.86 14.55 14.27 14.34 15.63 14.96 14.92 13.62 15.28 13.57 13.73 13.24 14.72 14.30 13.59 14.03 15.60 14.94 15.14 16.57 13.91 17.10 14.87 16.53 13.67 14.60 14.22 14.19 15.55 16.24 16.35 14.20 15.25 14.13 15.06 14.71 16.05 14.40 17.57 15.57 16.08 14.79 16.52 17.85 17.92 16.70 17.12 15.92 15.30 14.59 14.22 14.88 15.83 14.50 14.40 15.82 16.52 14.32 14.75 12.75 16.34
DLADGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 14.37 15.84 14.68 15.27 14.71 15.77 14.79 13.36 16.08 15.12 14.88 15.10 14.61 14.16 14.98 15.19 14.76 14.59 14.75 14.77 14.08 14.42 14.93 14.16 14.71 15.51 14.33 15.44 15.74 14.58 14.93 13.86 13.91 15.22 15.44 14.84 15.45 14.11 15.18 15.54 14.90 14.23 15.77 14.45 15.33 15.64 15.63 15.81 15.65 15.31 14.97 15.61 14.69 15.26 15.64 15.57 15.49 15.68 15.91 15.36 15.75 15.79 16.52 15.50 16.83 15.86 16.27 15.41 15.65 15.69 14.48 16.30 16.47 16.06 15.89 14.64 15.60 15.28 14.68 14.42 15.31 16.26 14.70 15.67 15.71 15.85 15.99
FAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRA 16.80 18.01 16.99 18.85 16.99 17.73 18.58 17.98 17.52 16.61 18.31 16.37 17.30 16.67 18.75 16.76 15.78 15.73 17.61 16.19 16.69 17.38 17.69 18.61 18.55 16.45 17.54 18.09 17.49 17.15 17.82 17.48 18.21 18.87 17.71 16.40 17.90 17.46 16.80 17.70 17.24 17.59 16.48 17.48 18.64 18.83 18.29 19.01 18.04 18.65 18.21 18.31 17.51 17.50 18.95 16.60 16.54 17.41 17.33 18.45 17.43 17.06 18.42 17.42 18.34 18.46 17.87 18.65 17.86 18.51 17.95 18.56 18.56 17.09 17.86 17.08 16.99 18.75 18.43 17.70 18.81 16.61 16.55 17.53 16.46 16.04 18.25
AVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 13.27 14.94 14.86 13.87 14.17 15.33 13.83 12.70 15.23 14.44 15.34 14.90 13.89 13.87 14.48 12.27 13.33 14.95 14.64 14.57 13.52 13.37 15.62 14.01 14.52 14.58 15.73 14.67 16.09 13.87 15.98 12.90 14.86 12.36 15.25 13.22 14.83 14.05 15.80 15.10 13.72 13.04 13.35 14.43 15.31 15.07 16.14 14.53 13.63 15.13 15.02 14.24 14.27 13.73 15.98 15.38 15.27 14.16 14.88 13.86 12.70 15.18 16.15 15.35 14.72 14.60 15.62 14.70 14.16 14.70 13.68 17.52 15.49 14.56 14.35 13.36 14.52 14.80 15.43 13.61 12.96 14.74 14.02 14.38 16.20 14.56 14.81
VADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 12.88 13.47 14.16 13.94 12.51 13.03 13.98 12.25 13.91 13.06 12.19 12.65 12.16 13.68 17.75 13.37 14.29 14.43 13.10 14.28 12.98 13.02 14.39 13.26 15.06 13.41 14.94 16.20 14.40 13.27 13.03 13.29 13.82 14.25 13.36 14.13 13.94 12.01 13.65 13.84 12.40 14.07 13.02 13.68 14.37 14.50 13.77 14.74 13.62 14.51 13.63 14.06 14.31 13.90 13.74 13.28 15.39 12.14 10.54 14.72 12.93 14.38 13.33 11.44 11.80 12.64 16.97 14.13 15.09 13.60 13.45 15.29 13.98 13.56 13.54 16.50 14.32 12.40 14.56 14.16 14.29 14.49 13.68 12.64 12.80 13.42 14.84
EEKAVADTRDQADGSRASVDSGSSEEQGGSSRA 17.60 18.70 16.31 18.37 16.39 18.33 19.13 18.66 16.82 17.30 18.84 16.62 18.12 16.21 18.29 17.21 17.14 17.81 18.66 18.32 18.19 17.70 16.79 17.79 17.12 17.22 18.67 17.29 17.30 16.89 17.56 17.15 17.57 18.61 16.91 18.65 16.12 16.78 16.66 18.88 18.29 16.62 18.37 18.37 18.52 19.02 17.91 19.29 18.83 17.95 18.16 17.78 17.94 17.47 18.67 16.07 17.19 18.40 17.03 17.87 17.90 17.29 18.53 18.43 17.08 19.07 19.28 19.55 16.66 17.31 17.02 18.41 18.90 17.98 17.55 19.46 18.61 17.98 17.57 18.71 19.16 17.63 17.57 18.64 17.08 17.51 17.51
DGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 15.45 17.27 15.76 17.40 15.24 16.10 17.47 14.96 17.38 16.69 16.31 17.44 17.17 17.55 16.69 16.53 15.15 16.24 15.92 16.92 15.43 15.93 16.85 16.19 16.57 16.83 16.32 16.00 17.77 16.47 16.80 15.55 16.00 17.08 16.22 16.45 15.43 16.23 16.71 17.08 16.44 16.69 17.25 16.00 17.37 16.78 17.64 18.03 16.98 17.24 17.14 17.71 17.57 17.11 18.12 17.33 18.28 17.75 17.56 16.63 17.67 17.24 17.80 16.45 18.63 17.38 17.97 17.26 17.33 17.33 16.91 17.56 17.97 16.92 17.74 18.89 17.49 17.88 17.57 17.28 18.09 17.42 16.74 18.41 17.80 17.66 17.80
IAVEWESNGQPENNYKTTPPVLDSDGSF 11.11 11.28 17.39 13.16 15.11 12.26 14.43 13.67 15.08 10.73 14.89 14.22 14.46 14.23 13.15 13.88 12.86 14.84 13.76 13.88 15.22 14.96 13.95 13.03 11.11 5.95 14.25 13.34 14.59 13.80 14.49 14.16 13.41 12.97 15.07 15.29 14.85 14.30 13.69 13.19 15.24 15.01 16.18 14.42 15.13 11.41 12.24 14.96 15.06 8.89 14.20 14.58 15.74 12.62 13.51 12.70 14.19 14.36 14.84 8.24 14.76 13.05 14.04 16.42 11.77 14.25 15.18 12.57 13.39 15.19 14.62 13.87 13.31 13.10 9.17 13.99 15.11 13.33 16.22 14.28 8.72 13.29 13.90 12.32 14.76 15.00 14.32
EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ 14.51 14.95 12.25 13.20 14.30 15.17 15.02 17.07 11.15 15.37 15.86 16.28 16.51 15.09 16.66 18.11 14.40 13.02 14.69 13.07 13.85 14.87 15.54 15.63 16.44 15.28 15.75 14.62 14.70 16.05 15.42 18.12 16.33 16.03 12.09 13.78 16.61 14.06 14.09 13.43 13.67 14.73 17.51 15.38 15.06 14.24 13.90 17.49 15.14 15.70 16.73 12.73 15.93 14.19 17.78 16.91 15.54 15.46 13.52 14.35 15.28 16.42 12.76 15.50 14.25 16.39 17.74 16.89 15.54 15.73 15.89 15.10 15.30 14.81 14.22 16.20 13.58 16.92 13.91 15.09 14.76 14.62 14.84 16.06 16.58 15.06 15.57
TWLNPDPSQKQNLLAPQNAVSSEETND 14.85 14.52 14.56 14.43 7.10 14.64 14.83 13.23 7.62 10.69 12.53 13.81 11.38 11.13 10.77 11.82 14.01 9.09 11.74 11.93 13.41 14.23 13.87 13.65 9.07 10.55 11.72 13.06 11.11 11.73 13.19 12.22 13.42 11.35 15.47 14.26 15.20 14.50 12.58 9.55 13.01 14.10 11.93 15.50 11.36 14.45 10.42 14.80 8.98 12.24 13.50 14.40 13.51 13.66 11.52 14.16 12.27 12.81 16.13 12.96 15.06 15.66 14.57 14.58 12.29 14.30 15.19 7.19 14.24 14.07 14.25 11.12 13.96 12.51 13.62 16.34 12.72 12.93 15.47 13.66 11.78 12.95 13.18 11.84 13.72 14.50 11.53
AIPVAQDLNAPSDWDSRGKDSYETSQL 14.87 12.09 13.87 11.27 13.23 12.26 13.44 13.83 11.36 11.86 11.85 13.85 14.31 12.15 12.61 12.89 15.04 9.10 12.23 13.65 13.03 11.59 11.86 12.95 12.49 13.58 11.31 12.49 13.94 11.47 13.89 14.61 14.68 15.14 14.32 9.61 14.62 12.89 13.18 10.14 13.39 11.64 10.76 15.08 12.51 14.46 13.17 8.67 13.45 11.89 13.01 14.71 11.84 13.77 9.48 15.74 13.75 13.70 13.65 12.72 13.57 15.55 11.53 12.49 13.74 15.05 13.54 13.99 14.11 13.74 11.87 14.10 5.59 15.17 11.39 12.04 13.13 15.41 10.11 14.01 12.32 13.17 13.26 9.75 12.33 12.41 14.01
LAQELPQQLTSPGYPEPYGKGQESSTD 13.14 13.26 11.83 11.71 10.47 10.47 13.68 13.44 11.93 8.29 12.49 13.49 13.05 13.35 11.27 12.20 9.87 12.68 12.75 12.95 11.77 11.58 11.75 13.22 12.18 13.40 11.87 11.42 12.32 11.92 12.32 12.36 11.34 12.09 12.31 13.68 12.47 12.46 10.76 11.71 11.83 13.48 11.92 12.89 13.98 13.89 11.40 13.41 12.84 14.08 13.60 13.33 12.83 12.51 12.85 14.57 12.81 12.74 13.65 12.36 13.83 12.44 12.53 12.80 17.51 12.65 12.48 12.74 13.55 13.24 13.20 12.12 13.50 13.02 13.62 11.68 12.79 12.43 11.73 12.58 13.25 13.32 12.77 13.79 13.67 13.18 12.88
WLNPDPSQKQNLLAPQNAVSSEETND 16.29 13.72 10.40 13.77 13.87 13.65 14.29 11.23 15.00 13.28 13.48 12.91 8.46 14.12 11.98 12.18 12.60 13.17 12.21 12.95 14.07 14.56 13.76 12.42 10.50 13.57 11.75 11.96 13.37 12.11 12.84 12.48 12.78 13.31 13.93 12.62 14.07 14.40 12.90 11.06 13.03 11.02 11.41 13.57 14.09 15.68 12.94 14.12 13.53 9.18 14.07 13.66 12.86 13.46 10.55 12.96 11.95 13.51 10.75 13.76 14.49 14.12 12.57 11.03 11.25 12.43 14.19 13.87 15.18 13.54 12.84 10.93 13.42 12.54 14.46 13.65 12.89 12.49 14.56 11.85 11.89 12.52 13.46 14.45 12.32 14.61 10.73
IPVKQADSGSSEEKQLYNKYPDAVAT 17.91 19.93 17.22 17.15 17.67 17.13 17.37 17.62 19.63 17.35 17.23 17.55 17.40 18.69 16.77 17.14 17.78 12.56 16.09 18.06 16.95 17.08 18.86 17.72 18.32 18.80 16.91 16.64 17.63 16.21 16.80 15.97 17.23 16.73 16.38 17.38 16.57 18.10 17.70 17.77 18.55 16.83 16.71 17.46 18.55 17.74 19.19 18.53 18.96 17.06 17.08 19.02 18.02 19.00 17.59 19.71 17.78 18.06 17.63 17.85 18.56 17.58 17.67 18.64 19.03 18.33 20.98 17.83 17.90 17.73 18.50 17.43 19.03 19.30 19.65 20.14 18.33 19.42 18.22 19.19 19.16 18.31 18.32 18.47 19.47 19.17 17.45
EAEDLQVGQVELGGGPGAGSLQPLALEGS 13.62 13.96 13.00 13.27 14.97 14.28 11.36 14.08 12.97 13.44 11.68 12.52 11.13 12.61 13.30 14.39 12.76 10.61 12.66 10.12 14.13 15.68 14.68 14.08 12.54 14.12 15.24 14.59 11.39 12.21 15.58 13.17 11.85 11.87 14.53 10.97 13.81 10.76 14.85 13.85 9.69 11.29 15.54 14.23 14.39 13.48 16.26 15.05 16.44 14.23 13.86 14.75 14.71 9.55 14.61 13.85 12.44 12.17 14.64 12.07 13.87 13.77 12.27 13.11 14.66 15.15 15.49 14.72 13.01 15.63 14.14 14.49 14.27 15.09 15.17 14.62 14.59 14.49 15.40 12.92 12.32 13.97 13.72 13.89 12.64 15.24 12.55
TAQLDEELGGTPVQSRVVQGKEPAHL 13.81 13.70 13.86 11.67 15.20 14.17 13.30 15.23 11.75 13.22 15.76 13.36 14.32 14.44 14.13 14.64 12.72 15.19 14.04 14.63 14.87 14.59 13.85 13.49 14.39 15.03 11.22 12.51 10.03 13.38 14.89 15.52 15.26 15.41 14.65 14.63 15.20 14.24 14.03 13.54 12.77 12.37 13.40 14.58 15.50 13.83 18.03 15.51 15.44 15.76 15.27 12.07 13.31 14.46 15.91 15.88 15.87 15.40 10.47 15.34 16.36 15.27 14.11 13.17 12.84 12.68 15.38 14.16 15.87 16.67 17.30 17.10 15.15 14.34 13.59 12.61 14.03 13.20 14.39 14.73 13.92 14.69 15.08 13.34 12.65 12.37 14.88
IPVKQADSGSSEEKQLYNKYPDAVA 18.25 16.41 13.59 17.18 16.61 16.81 20.34 16.50 14.60 17.39 17.72 20.16 17.59 18.01 17.20 17.15 13.94 17.14 17.58 17.77 16.60 16.42 17.73 18.80 18.51 17.07 16.87 14.68 17.59 16.49 17.35 16.04 17.27 16.94 12.90 14.27 14.86 17.22 16.79 15.56 17.80 17.63 16.05 12.48 18.53 18.67 17.88 18.46 13.00 18.94 17.87 18.62 19.91 18.85 18.43 21.51 18.19 19.78 19.94 18.63 19.95 18.98 19.65 11.45 17.63 20.79 14.13 18.73 18.28 17.64 20.40 16.28 18.32 17.21 19.99 19.77 18.70 19.55 19.54 20.97 19.23 17.45 18.61 19.07 18.92 20.17 16.50
AQLDEELGGTPVQSRVVQGKEPAHL 13.56 13.69 14.02 13.79 14.81 13.86 12.74 14.08 11.05 13.17 15.38 13.11 14.00 13.43 13.87 13.76 14.04 14.86 12.73 13.41 14.50 14.37 12.96 12.65 12.48 14.18 13.39 15.76 14.12 12.93 14.10 14.95 14.38 14.61 13.71 14.28 14.49 13.52 13.16 13.03 12.75 13.14 13.59 13.85 15.15 14.31 13.82 15.00 15.59 14.95 14.53 12.56 13.52 14.14 15.56 14.44 14.90 15.12 10.47 14.86 15.59 15.03 14.16 14.89 10.16 11.83 14.80 14.59 15.09 16.22 16.20 16.38 14.36 13.87 13.04 16.34 13.82 13.54 14.29 12.89 12.65 13.44 14.23 14.84 12.80 12.07 14.48
VKQADSGSSEEKQLYNKYPDAVAT 16.36 18.05 15.05 15.06 16.52 14.46 17.70 17.10 18.31 16.51 14.84 15.41 16.46 17.89 15.01 16.79 15.07 12.78 15.22 16.38 15.53 16.62 17.35 15.62 15.99 16.17 15.72 15.99 15.32 15.93 15.53 14.69 16.46 15.63 16.00 14.93 15.51 17.29 15.60 15.88 16.55 15.34 15.12 16.05 15.77 15.92 15.64 18.28 16.89 14.37 16.64 17.68 14.92 17.36 12.73 17.76 15.46 17.14 16.74 16.69 17.26 16.37 16.24 16.78 16.17 15.37 18.71 15.88 15.89 15.53 15.81 15.71 17.58 16.52 16.64 16.62 16.46 17.29 17.29 15.86 17.42 17.41 17.03 16.24 16.92 17.70 16.01
LSDPEQGVEVTGQYEREKAGFSW 13.85 14.81 15.98 10.16 15.08 13.60 15.79 14.69 12.79 14.05 15.55 10.23 14.98 14.53 12.63 13.29 15.13 16.12 15.45 14.46 13.32 13.88 13.09 12.81 15.63 14.53 14.09 16.23 12.84 14.73 13.80 14.13 14.52 13.26 15.93 14.10 15.60 14.45 15.16 16.20 14.58 13.73 12.00 15.37 14.26 15.52 12.35 15.40 15.43 15.52 15.27 16.03 14.69 14.76 15.96 15.53 15.39 14.75 14.48 15.56 15.96 15.98 14.92 16.50 13.62 15.24 14.36 16.52 16.26 13.78 14.28 15.08 14.36 15.28 14.45 15.00 15.13 14.27 9.79 14.62 10.29 14.83 15.76 15.83 15.18 14.54 15.43
MVEHTPDEESIDWTKIEPSVNF 14.16 15.26 14.38 14.51 14.67 14.36 11.27 11.83 11.60 13.25 14.99 13.98 14.35 13.98 13.31 11.03 13.71 14.38 13.17 15.19 13.97 13.78 14.74 15.52 15.15 14.63 13.27 15.02 13.50 13.21 14.00 14.03 14.44 13.07 15.25 13.60 14.83 13.13 14.52 14.70 12.69 12.69 12.43 14.58 15.02 15.29 14.81 15.12 15.40 15.09 14.17 14.43 13.13 13.76 14.72 10.78 15.30 14.65 13.77 12.32 15.01 15.54 15.27 15.52 16.11 13.43 13.28 15.08 16.30 14.83 14.12 16.22 14.40 15.12 13.93 13.78 15.01 14.19 15.74 14.85 11.02 13.93 13.57 9.56 9.73 13.26 14.26
AQDLNAPSDWDSRGKDSYETSQL 11.13 16.83 13.92 13.14 14.12 12.16 13.34 12.88 15.61 14.23 11.59 13.26 11.34 16.17 9.74 13.16 13.56 13.89 11.86 15.31 14.47 11.50 11.16 13.66 13.81 14.50 12.15 14.18 13.90 14.72 10.74 14.99 14.12 13.48 12.66 11.59 13.30 12.68 16.20 13.21 11.11 13.60 17.59 15.34 11.45 14.41 14.73 13.18 18.12 12.22 9.20 16.98 13.82 15.01 13.46 14.10 13.53 13.51 16.82 16.15 14.06 15.00 11.40 15.34 15.83 14.53 15.34 13.42 12.57 15.57 13.48 12.52 16.72 14.03 13.73 17.37 11.98 15.51 12.83 13.17 15.45 16.12 15.74 13.78 12.72 12.68 16.43
EDPQGDAAQKTDTSHHDQDHPTF 15.16 14.78 14.35 14.75 14.14 14.88 13.65 13.69 15.08 14.88 14.70 14.38 14.43 14.91 14.55 14.90 15.28 14.72 14.24 15.42 14.27 12.52 13.98 15.60 14.44 15.81 15.22 15.99 14.76 14.74 14.35 14.21 14.68 13.43 14.81 12.67 13.47 13.81 14.55 14.52 15.21 15.57 14.77 14.78 15.50 14.63 15.85 14.96 16.52 14.94 14.37 17.16 15.12 15.47 14.21 16.28 14.72 14.60 15.19 14.87 14.52 15.27 16.01 17.49 15.88 14.61 16.87 14.25 13.79 15.15 14.81 14.84 16.20 15.76 16.09 16.75 16.29 15.29 15.82 16.88 14.54 16.85 15.61 14.70 16.47 15.46 15.23
IPVKQADSGSSEEKQLYNKYPDA 16.76 16.44 17.47 14.58 15.62 16.07 17.11 16.20 14.62 14.83 15.79 16.93 15.15 13.29 15.26 13.97 15.98 14.49 15.19 16.33 15.61 16.11 17.08 15.93 16.25 15.32 14.45 15.73 15.29 13.96 15.43 14.40 14.78 14.61 13.95 15.11 14.59 16.39 15.61 14.15 16.31 12.97 17.64 13.28 17.72 16.70 14.63 16.68 15.95 16.10 14.95 17.48 16.72 16.55 15.35 15.88 14.17 15.74 15.26 14.58 16.68 16.98 16.73 12.46 16.26 17.73 15.53 15.86 15.75 16.27 16.68 14.33 15.82 15.69 16.94 17.77 16.00 16.66 16.23 18.03 15.82 15.52 15.80 15.93 16.73 17.55 14.46
LSRQELFPFGPGQGDLELEDGDD 13.22 14.51 12.42 13.07 14.01 14.36 11.89 13.36 11.66 12.77 14.32 11.96 13.80 12.19 13.74 13.19 10.31 14.44 13.61 13.70 14.69 14.84 13.82 13.36 14.09 14.16 12.15 13.08 11.05 12.17 11.42 13.60 13.32 13.22 15.12 13.12 14.73 13.27 13.27 12.95 13.22 13.81 13.88 14.40 14.39 12.84 16.78 15.25 14.07 13.62 13.73 13.10 12.35 13.24 14.25 14.58 11.90 13.26 12.63 13.93 14.70 14.71 13.98 14.04 11.34 13.25 15.44 8.58 12.94 15.16 15.05 14.50 13.78 13.45 14.83 13.55 13.62 12.31 15.18 12.26 13.14 14.05 13.03 9.99 13.19 13.99 14.87
VKQADSGSSEEKQLYNKYPDAVA 16.55 14.12 16.93 16.57 16.88 15.47 18.29 16.18 17.43 16.98 15.66 16.32 16.86 15.31 15.21 16.06 17.23 12.71 15.63 15.74 15.51 16.69 17.19 16.58 15.66 13.92 15.52 17.16 15.83 16.37 16.41 15.10 17.00 16.56 12.94 15.53 15.04 17.36 16.14 14.54 16.46 16.20 13.54 13.99 17.25 16.24 17.62 17.68 16.79 15.86 16.92 17.42 17.09 17.23 14.45 17.61 14.96 17.34 17.03 16.04 17.46 16.65 17.78 17.17 15.91 16.95 12.76 16.71 16.23 15.28 16.96 15.55 17.64 15.55 17.01 17.17 16.52 18.07 17.97 17.14 17.69 17.32 17.41 16.72 17.35 18.32 15.90
EAEDLQVGQVELGGGPGAGSLQPLAL 15.52 14.30 11.90 16.88 17.43 12.80 12.96 13.49 8.13 14.97 14.44 15.57 16.57 14.77 16.63 17.59 13.14 15.28 16.10 12.55 14.11 14.98 16.88 16.08 15.62 16.29 13.96 14.71 15.47 15.88 13.74 15.67 14.70 14.07 14.11 12.86 14.92 12.95 12.98 14.59 12.84 16.46 14.44 14.97 15.90 15.04 16.39 13.93 15.19 16.70 16.51 14.24 17.63 16.16 18.79 16.61 16.15 16.79 11.00 13.82 15.56 16.47 11.80 16.63 13.88 15.13 15.80 18.01 17.27 15.57 16.13 14.34 13.84 15.00 16.52 14.26 15.12 16.47 16.00 14.29 15.08 15.53 14.64 16.25 16.82 17.14 16.02
IAVEWESNGQPENNYKTTPPVL 14.37 14.20 16.71 14.26 16.18 13.68 14.56 13.36 15.62 12.33 14.51 13.87 14.31 14.99 14.15 14.88 16.98 17.42 16.32 15.12 15.16 15.19 16.54 14.49 14.53 15.76 13.96 10.49 15.23 14.59 15.20 14.20 14.77 13.88 17.42 16.84 17.48 14.44 14.36 15.41 16.43 15.62 12.19 11.99 14.01 15.04 17.03 14.55 15.69 15.48 15.18 16.91 15.66 12.69 15.26 15.11 12.92 16.57 16.77 14.29 16.44 17.98 17.00 18.51 13.78 13.12 14.75 15.98 16.26 15.57 16.29 14.75 15.07 15.80 15.41 14.74 16.01 11.46 13.35 15.46 13.71 17.12 16.57 11.00 15.98 14.56 17.04
AKADAAPDEKVLDSGFREIENK 13.86 14.83 14.23 14.66 14.21 14.35 14.18 14.05 15.09 13.69 14.19 13.08 14.27 13.70 13.50 14.32 14.34 14.40 14.40 14.80 14.52 14.75 12.95 13.39 14.80 15.19 15.28 15.73 14.42 15.30 12.24 14.25 13.86 13.61 15.28 13.77 14.99 14.25 14.10 12.91 14.69 13.64 15.01 14.22 14.73 14.94 13.16 15.14 16.64 14.72 14.85 16.28 13.13 12.67 14.18 14.91 15.25 14.35 17.36 15.22 14.96 15.49 14.68 15.90 15.95 14.46 14.85 15.19 14.37 14.01 12.17 14.90 15.90 15.78 15.64 16.07 14.77 13.41 12.78 14.95 14.50 15.53 14.73 15.07 15.69 14.86 15.60
FKQETLPSKSNESHDHMDDM 15.19 14.53 14.23 14.91 14.64 15.41 16.31 14.85 14.55 15.48 14.54 13.80 15.64 15.96 14.05 14.83 14.94 13.45 14.43 15.09 14.28 15.45 15.79 16.06 15.23 15.31 15.59 14.25 15.16 13.65 15.15 13.64 13.99 14.79 13.12 14.72 12.24 15.45 15.48 15.97 16.11 14.20 16.21 14.22 16.08 15.19 16.25 16.21 14.84 15.24 15.48 16.54 14.86 15.80 15.11 17.48 15.03 15.70 16.24 14.60 15.63 15.92 16.73 15.13 15.35 16.04 12.59 15.20 15.60 15.53 15.91 14.81 16.01 14.63 17.07 17.85 15.56 15.73 16.07 16.32 15.11 14.36 16.23 15.67 15.30 17.47 11.97
DEELGGTPVQSRVVQGKEPAHL 15.49 15.83 14.79 16.75 16.24 11.67 15.40 16.44 16.77 16.38 15.96 16.83 15.75 16.26 14.27 15.67 16.80 13.61 15.49 15.79 15.35 14.74 15.17 15.91 17.69 16.19 16.13 15.40 14.55 15.31 16.35 16.03 16.19 17.24 15.11 15.89 14.29 15.52 15.39 15.41 14.57 15.96 16.38 15.87 16.65 15.88 18.59 16.30 15.59 17.23 16.31 17.42 16.20 17.05 17.50 15.40 16.87 16.57 15.90 16.57 17.27 16.46 15.76 16.96 18.88 15.10 16.48 16.02 17.10 17.39 18.18 18.13 16.39 16.30 16.32 15.68 16.74 16.23 16.18 15.97 16.77 16.13 16.41 16.62 15.42 15.51 16.43
LSDPEQGVEVTGQYEREKAGF 14.49 14.32 15.23 17.17 17.00 16.73 16.00 14.71 14.13 15.42 16.16 11.78 12.51 17.05 15.54 14.32 16.34 15.67 16.80 15.54 13.35 13.60 14.33 13.07 13.14 15.45 16.27 17.40 15.61 16.85 15.57 14.31 16.15 15.45 13.73 14.81 15.65 15.68 16.35 15.36 15.53 16.22 14.05 15.78 17.75 16.31 17.48 14.25 16.33 16.55 16.32 16.63 16.57 16.73 17.52 14.70 16.29 15.85 16.40 16.68 16.52 16.88 14.00 17.58 18.66 17.30 16.31 15.12 16.77 14.76 16.00 15.59 14.43 14.84 15.05 15.12 15.53 17.13 16.44 15.93 16.08 15.89 17.88 16.56 18.13 17.00 16.51
LNAPSDWDSRGKDSYETSQL 15.18 13.78 15.69 13.45 14.05 14.13 15.73 15.14 12.75 15.34 13.03 15.30 15.44 14.95 12.65 15.13 13.59 13.50 13.82 14.66 14.04 13.53 15.09 14.60 14.20 14.17 13.61 14.23 14.27 13.97 14.42 13.26 13.73 13.71 12.72 14.06 13.98 16.08 14.97 14.99 15.10 13.81 14.02 14.62 14.77 14.98 12.73 15.27 14.49 14.19 15.31 16.30 14.55 14.93 14.08 18.13 14.63 14.60 15.45 13.74 14.66 15.11 15.25 15.86 13.52 15.57 15.65 15.04 15.23 14.75 15.05 13.93 15.24 15.22 14.77 16.52 15.58 15.03 15.14 15.71 14.64 15.27 14.56 14.51 15.64 16.42 14.45
FKQETLPSKSNESHDHMDD 14.81 14.35 13.28 15.49 14.42 14.73 14.92 14.79 14.94 15.00 13.17 14.44 14.45 14.19 13.98 15.30 14.12 14.00 13.60 14.95 14.59 14.67 15.20 15.29 14.68 15.09 14.87 15.09 14.56 13.72 14.85 13.03 12.24 14.24 14.06 14.69 13.74 15.18 15.16 15.77 15.52 13.43 15.92 13.67 14.86 15.17 15.15 15.26 15.15 15.10 15.25 15.88 14.88 16.27 14.19 16.43 14.44 15.23 15.31 13.89 15.27 14.42 15.08 14.01 14.23 15.48 13.39 15.18 15.65 14.58 13.87 13.65 14.98 14.06 16.94 16.00 14.97 14.77 15.45 15.12 14.56 14.04 15.06 14.69 16.16 16.78 14.80
EAEDLQVGQVELGGGPGAGSLQP 12.86 13.30 12.82 13.40 12.08 13.40 13.82 11.12 12.91 11.72 13.70 12.25 14.35 13.63 13.26 12.12 14.80 13.79 13.04 13.70 11.75 13.10 12.32 13.46 14.00 13.44 13.35 14.32 13.57 14.61 13.30 14.98 11.88 12.31 12.27 12.26 13.75 10.70 12.82 13.43 11.52 12.51 13.92 12.68 13.84 14.02 12.32 11.09 13.55 12.74 13.50 13.95 13.60 13.09 14.02 10.27 14.59 13.13 14.15 12.42 13.83 15.19 9.93 11.41 15.17 13.82 14.86 14.25 13.71 12.98 13.36 13.72 12.18 14.64 12.24 13.25 13.45 14.53 12.20 11.06 13.60 13.94 12.82 14.48 13.25 13.31 12.20
LVLTGYQVDKNKDDELTGF 14.43 14.51 16.65 14.76 14.99 14.37 15.93 15.58 17.35 10.86 16.09 14.75 14.37 15.22 14.88 15.26 14.36 13.44 14.57 13.99 12.45 13.40 16.29 14.97 15.04 12.69 13.42 15.94 15.22 14.01 15.30 15.09 14.82 14.18 12.89 14.17 15.33 15.81 15.08 14.96 13.94 14.60 12.81 15.27 14.00 14.75 14.92 11.47 15.44 15.58 15.09 17.04 15.92 16.30 12.40 15.45 16.04 14.03 12.90 15.89 15.36 15.18 15.45 14.66 15.32 17.57 13.11 15.46 13.67 15.32 15.27 15.25 16.02 12.18 16.21 14.27 14.28 15.99 13.82 16.22 15.26 15.78 13.21 16.00 14.44 13.83 13.92
VQVFAPANALPARSEAAAVQP 13.86 14.76 10.48 13.27 11.46 14.96 15.04 12.06 14.90 13.84 14.17 13.75 15.32 14.20 11.81 13.32 10.65 15.44 14.07 13.44 13.16 12.63 14.00 14.79 13.64 15.23 13.47 12.56 14.52 13.42 10.65 11.17 12.03 13.20 14.10 13.24 13.75 13.86 13.64 13.90 14.27 14.16 14.89 13.23 13.86 14.51 15.53 15.96 12.99 14.64 14.45 13.48 13.94 13.18 15.56 16.58 14.72 15.64 12.43 15.49 14.34 9.48 13.69 14.35 14.57 13.57 11.96 14.61 15.23 13.94 14.58 15.49 15.90 15.41 15.59 13.03 11.53 14.86 13.63 14.49 14.49 15.59 14.50 14.33 16.21 13.93 13.86
DGQPGAKGEPGDAGAKGDAGPPGP 13.76 15.74 14.21 14.88 11.08 16.97 12.40 13.84 15.50 14.75 13.28 15.26 13.25 12.57 15.15 11.30 14.28 14.93 13.76 14.54 14.11 13.55 13.38 11.78 14.14 14.15 15.41 14.68 14.49 15.62 14.27 14.34 9.35 14.81 13.26 16.51 11.47 13.88 14.22 14.95 13.68 14.20 14.52 10.77 14.85 14.90 15.30 14.66 14.14 15.07 15.67 13.28 15.71 14.73 15.21 15.84 15.52 12.16 15.13 15.91 13.56 16.43 16.42 14.58 15.39 14.18 14.43 15.06 14.75 14.63 13.25 15.87 16.50 15.80 15.43 16.12 14.94 15.12 14.55 14.24 15.62 15.93 15.57 15.50 10.26 15.56 15.55
IILEHHVAQEPSPGQPSTF 13.99 12.83 14.06 11.84 14.93 12.88 13.67 12.28 12.86 12.37 13.45 12.64 13.71 11.96 12.23 13.32 14.61 13.98 13.85 12.70 14.23 13.76 13.07 7.22 11.91 14.48 9.69 15.68 13.90 13.46 12.54 12.97 12.16 13.26 14.70 13.19 14.63 13.38 13.89 13.73 14.58 13.15 13.35 13.75 14.39 14.44 13.89 14.49 15.03 13.57 14.46 12.47 14.34 14.31 15.84 13.09 13.85 14.23 17.12 14.68 14.58 14.81 13.57 13.70 13.25 15.45 13.83 13.15 13.82 15.19 14.68 14.44 14.58 14.46 14.53 12.59 14.04 14.90 13.94 14.76 13.54 14.81 14.27 15.01 14.39 13.77 14.41
DAHKSEVAHRFKDLGEEN 14.10 15.35 17.47 17.29 17.37 17.48 11.53 16.07 13.74 17.02 16.15 13.73 15.73 15.24 17.88 16.42 15.04 12.27 18.34 15.68 18.13 15.81 11.89 13.62 14.99 18.33 16.02 13.46 17.33 15.80 15.99 13.07 16.39 15.16 18.14 19.13 15.60 14.23 17.07 17.40 16.14 15.09 17.38 20.41 16.64 12.95 13.31 17.24 18.61 14.36 17.16 18.02 16.49 16.03 18.63 15.59 19.84 20.01 18.23 17.29 15.66 15.60 16.99 23.28 18.41 19.19 18.97 15.48 16.88 15.34 17.41 16.66 17.76 18.58 17.33 18.04 15.09 18.38 17.95 18.44 15.15 20.01 17.64 19.28 18.71 17.14 15.77
S(+42.01)ETAPAAPAAPAPAEKTPVKK 14.56 15.29 13.95 16.08 14.78 15.51 16.07 14.41 15.61 15.96 14.88 15.64 14.10 14.95 14.98 13.25 14.80 12.52 14.81 14.81 14.47 14.36 14.39 15.01 14.72 15.25 14.80 14.99 15.29 14.88 14.19 14.78 14.35 14.33 14.55 15.80 13.25 14.41 15.07 13.98 14.39 14.98 15.51 14.76 14.74 14.58 16.01 15.24 15.03 15.39 14.97 14.15 15.64 15.32 15.52 15.06 15.01 15.11 14.96 14.94 15.04 14.61 15.22 14.68 15.96 15.06 16.09 15.05 14.84 15.34 14.53 15.88 15.66 15.96 14.68 16.50 15.13 15.83 14.35 15.08 16.07 15.60 14.76 15.91 15.24 15.27 15.90
VVVKLFDSDPITVTVPVEV 13.59 8.61 9.72 14.50 15.93 10.92 12.38 11.82 11.96 13.39 10.55 12.61 7.45 12.29 13.27 13.91 11.48 14.14 13.08 14.18 14.40 12.16 10.79 12.65 9.36 13.34 12.12 10.16 14.20 13.85 15.53 9.82 10.39 9.83 15.62 14.10 15.33 12.69 14.31 11.48 11.19 10.05 14.76 15.16 10.03 14.05 12.03 14.88 12.09 13.77 12.73 13.48 13.65 14.07 10.31 11.09 14.80 12.45 13.51 13.92 12.27 8.62 11.77 10.51 13.74 15.25 14.68 12.51 15.67 13.51 14.31 13.48 12.55 11.19 9.64 10.56 13.50 14.35 16.92 15.41 14.91 13.70 12.74 10.58 11.26 12.52 12.03
S(+42.01)ETAPAAPAAAPPAEKAPVKK 14.01 14.95 14.84 15.61 14.14 13.97 15.60 13.48 14.48 15.64 14.60 16.22 13.78 12.76 14.77 12.62 14.66 12.89 13.08 14.23 13.95 13.78 14.26 14.65 14.02 14.95 14.31 14.46 14.83 14.51 14.08 14.34 12.90 14.15 14.04 15.40 12.99 13.93 14.60 13.90 13.95 14.45 14.40 14.40 13.63 13.84 15.49 14.56 14.13 15.14 14.29 13.58 15.40 14.94 15.10 14.74 15.44 14.49 14.01 15.06 14.58 14.12 14.80 13.98 14.98 14.81 15.61 14.66 14.33 14.83 13.90 15.65 15.31 15.63 14.10 16.27 14.66 15.17 14.29 14.90 15.54 15.08 14.24 15.42 14.99 14.50 15.44
VLTGYQVDKNKDDELTGF 16.30 16.44 17.10 15.78 16.17 14.69 15.52 14.75 17.35 15.63 17.23 14.31 15.72 16.40 16.88 16.59 14.74 16.35 16.62 15.65 12.88 15.45 18.09 15.58 15.88 14.58 15.12 15.74 17.34 15.78 15.65 15.09 16.15 14.96 16.70 17.21 14.68 16.60 16.84 16.10 15.79 16.36 14.93 16.21 15.71 16.05 15.99 15.35 16.40 16.48 16.70 15.59 10.41 17.34 15.69 16.81 17.09 16.01 15.88 17.17 15.59 17.16 15.88 15.43 16.55 17.67 11.23 16.53 14.78 15.50 15.76 16.40 17.15 12.63 17.22 12.37 15.10 16.98 16.50 16.47 16.63 16.80 15.15 16.33 16.25 15.48 15.09
KANDESNEHSDVIDSQEL 15.97 14.49 13.59 12.72 13.98 14.18 13.98 13.96 12.39 15.02 14.50 12.39 13.71 13.82 14.98 13.09 13.76 14.91 13.49 13.73 12.10 13.61 14.95 14.23 13.88 13.72 14.63 14.23 14.46 13.51 13.83 12.71 14.23 13.10 12.44 12.81 13.06 13.79 13.93 13.80 14.82 13.59 13.32 13.39 14.71 14.75 14.71 14.02 13.92 12.89 13.45 14.29 15.59 13.59 15.03 15.49 13.39 13.27 11.80 14.19 14.07 14.66 14.95 12.51 14.70 13.55 15.33 14.69 13.98 13.01 13.94 12.53 13.63 14.18 14.81 12.49 13.68 14.27 15.08 14.39 14.05 13.71 14.81 13.55 15.78 16.56 12.51
ASHTSDSDVPSGVTEVVVKL 11.93 13.89 12.60 12.87 14.52 12.23 11.70 12.56 13.42 12.70 12.85 13.11 13.76 13.34 12.98 13.76 12.40 13.27 12.39 13.90 14.63 14.18 13.35 12.48 13.11 12.14 13.73 12.33 12.01 12.16 13.46 13.05 12.25 12.31 13.79 13.34 13.68 13.12 13.80 12.76 13.41 12.08 15.09 13.50 14.86 12.10 12.14 13.31 12.59 12.40 12.42 11.86 14.21 12.79 12.51 12.67 12.72 12.43 14.48 10.90 11.47 11.26 13.23 13.28 12.57 13.06 13.93 12.46 13.59 14.80 13.23 13.53 13.73 13.31 14.51 12.73 12.82 11.75 14.32 13.27 10.66 12.57 13.40 12.36 12.10 12.82 11.96
AKVQWKVDNALQSGNSQE 16.35 14.33 14.10 15.06 14.05 15.72 16.94 15.41 14.43 16.56 14.02 14.95 13.31 13.45 9.85 16.95 15.03 13.05 14.29 12.96 16.84 17.27 14.55 15.79 13.37 15.65 16.80 10.61 9.50 11.19 13.79 14.94 13.53 13.19 12.16 12.20 13.33 13.89 12.33 13.93 13.12 13.10 17.83 18.94 17.42 16.01 14.75 14.99 15.79 17.18 11.73 16.23 12.26 12.15 14.86 15.15 13.74 14.64 14.65 15.12 13.01 15.36 17.55 14.90 14.83 17.08 16.63 11.67 14.40 13.55 16.15 16.47 17.43 17.03 15.16 17.19 16.15 17.22 13.13 16.68 15.53 14.89 13.84 15.79 14.10 14.30 14.66
VFEIGSPATTNGVVPADVIL 13.67 11.97 6.33 6.80 9.22 10.29 9.10 12.02 11.61 12.83 12.69 13.06 11.91 8.19 10.99 9.91 10.92 10.85 12.86 12.69 8.69 10.84 11.63 10.90 8.61 13.47 12.64 12.80 9.20 10.03 9.97 12.55 11.66 12.44 11.94 12.53 11.91 10.06 10.81 9.05 12.72 10.94 10.59 12.69 15.73 14.33 10.53 12.06 11.60 14.79 11.25 13.33 12.86 13.10 13.63 11.01 9.84 12.05 13.52 12.24 12.49 12.21 12.69 12.82 10.25 12.39 12.71 12.39 13.86 10.43 11.46 12.89 13.70 12.94 10.26 11.41 12.72 12.38 12.89 13.46 12.17 11.50 11.27 13.22 11.16 12.40 13.10
PSDWDSRGKDSYETSQL 14.66 13.41 13.45 13.41 13.37 13.78 14.09 13.65 14.56 14.83 12.40 13.08 14.72 14.19 14.27 13.26 13.49 13.03 12.35 13.78 14.99 13.85 15.11 14.56 13.62 14.02 13.00 13.54 14.54 13.36 11.87 10.29 12.50 12.39 14.20 13.39 10.23 14.20 14.57 13.35 14.51 13.51 14.71 11.35 14.85 14.47 14.38 14.92 11.77 14.05 13.67 15.17 13.93 12.88 12.93 15.61 12.82 13.38 14.26 11.96 14.10 14.84 14.22 14.89 13.91 13.17 11.39 13.84 14.47 13.00 12.46 13.42 13.02 14.05 13.53 14.07 14.97 14.41 14.86 13.90 13.12 13.65 14.55 12.85 15.69 15.94 12.66
FAEEKAVADTRDQADGSR 15.17 15.68 14.54 15.28 14.46 16.01 15.20 14.82 15.44 15.04 15.05 15.03 14.36 15.96 15.27 15.58 15.27 14.39 14.85 15.82 15.27 15.31 13.84 16.67 14.30 14.25 14.15 11.34 15.92 15.68 14.54 14.95 15.13 15.49 13.10 15.11 14.01 15.96 14.24 13.81 15.84 15.62 13.99 15.13 15.87 14.72 16.37 15.99 16.15 14.75 15.92 16.21 13.91 14.26 15.08 15.72 15.36 15.84 14.60 15.74 14.08 15.32 16.45 15.91 15.33 17.28 15.76 14.43 15.13 14.66 14.49 14.39 16.51 15.61 16.82 15.94 15.75 17.11 13.81 16.39 16.42 15.20 15.44 15.38 15.34 14.05 15.17
VVKLFDSDPITVTVPVEV 12.21 12.88 12.46 12.42 9.97 12.34 12.75 12.31 8.87 11.97 10.48 11.13 13.50 12.20 12.37 12.62 11.41 12.61 12.77 13.53 13.64 13.28 11.39 10.52 9.15 11.52 11.22 12.18 12.72 12.58 13.42 13.19 11.44 13.23 13.19 12.67 13.62 8.74 12.67 11.71 12.83 12.49 14.81 13.11 13.04 13.09 10.65 12.69 12.95 12.79 12.16 11.95 12.99 13.13 10.40 9.00 12.07 12.00 12.27 12.89 11.77 13.13 11.35 11.93 11.92 11.87 13.38 13.51 13.39 12.27 12.67 12.06 10.60 12.47 9.39 15.98 11.51 12.23 14.55 13.29 13.62 11.89 10.22 13.56 10.90 9.65 10.82
QVGQVELGGGPGAGSLQPLAL 12.31 10.94 10.76 9.71 9.23 7.63 9.73 12.67 10.77 13.43 13.32 15.49 12.45 11.04 10.18 9.72 12.16 10.67 12.35 13.01 8.69 11.64 12.71 11.47 11.97 12.00 12.95 9.72 10.29 11.31 11.66 12.12 12.01 13.05 12.30 13.32 11.90 12.05 12.62 11.87 13.36 11.37 11.69 12.13 15.87 11.92 10.59 11.07 10.32 13.81 12.22 13.19 12.55 13.03 13.63 12.08 11.14 11.71 12.69 12.49 13.68 11.30 14.06 10.53 11.32 8.80 12.61 11.05 15.11 8.65 13.34 11.30 14.00 11.41 11.99 11.70 12.21 13.37 9.90 14.14 13.01 10.67 7.77 14.19 11.06 12.47 12.05
S(+42.01)ETAPAAPAAPAPAEKTPVK 10.44 13.54 15.67 12.67 12.91 11.15 12.48 12.09 14.09 13.45 14.22 12.63 13.69 8.21 10.54 11.03 12.73 11.75 11.36 12.69 13.05 13.26 11.76 11.60 12.17 12.30 13.22 13.24 13.13 13.07 11.79 12.76 12.60 13.20 12.56 13.48 12.04 13.24 13.26 12.77 12.73 12.67 13.87 12.82 14.37 13.58 12.28 12.95 13.21 12.99 13.36 12.71 13.21 14.00 12.28 13.32 12.92 12.65 12.97 11.61 12.66 13.54 12.97 11.50 13.12 12.27 13.15 12.52 11.56 13.66 12.32 11.57 12.40 13.59 13.18 13.56 11.51 13.85 12.42 12.18 12.76 13.06 12.40 13.22 13.62 11.96 12.57
VSEDPINDGEWHRVTAL 15.17 13.96 13.70 13.37 14.18 13.96 13.91 13.53 14.37 14.78 12.11 14.08 14.07 13.93 12.62 12.79 15.41 14.43 13.50 14.61 13.82 12.10 13.54 11.07 12.11 14.23 15.36 15.80 12.96 12.80 12.09 13.35 13.64 12.47 13.48 12.90 13.68 13.60 13.54 15.52 13.39 13.61 15.21 13.30 15.01 15.66 14.02 10.70 13.18 14.07 13.01 12.93 11.39 14.72 11.59 14.82 14.61 12.10 15.61 13.36 12.41 15.02 14.77 13.34 15.42 15.04 16.05 9.98 15.16 13.58 10.09 13.95 13.55 15.26 13.80 13.71 15.74 14.17 14.82 13.33 13.31 14.50 13.50 14.18 13.01 13.20 14.56
FRTQTAPGGQGAPWAEEL 13.45 12.38 15.61 12.79 14.86 15.19 12.02 14.78 15.97 10.54 14.14 14.04 14.92 14.47 11.78 15.03 16.25 16.03 15.38 14.70 14.74 13.77 13.89 14.18 12.44 14.09 14.40 9.37 13.04 13.57 12.81 12.79 11.97 12.79 14.75 12.60 9.57 13.40 13.53 13.45 14.30 14.31 14.71 15.13 16.57 15.17 16.62 14.03 15.96 15.22 15.61 15.96 8.81 10.67 12.06 15.81 10.10 14.06 12.45 15.23 16.10 12.09 14.45 16.55 15.00 12.64 14.45 16.55 14.28 14.76 12.90 13.51 14.28 14.52 14.73 14.57 15.34 12.07 12.36 13.38 12.22 14.68 14.82 13.96 14.31 14.38 14.99
SGSVIDQSRVLNLGPITR 15.91 19.10 18.09 17.92 19.78 18.34 19.11 19.34 19.90 19.89 16.40 19.80 19.89 18.65 17.89 18.23 14.13 16.29 15.80 16.98 17.86 17.23 18.75 17.05 14.61 17.55 18.98 18.33 18.88 18.05 19.29 19.79 17.39 18.58 16.02 16.48 15.64 19.76 18.46 17.93 18.92 16.85 15.27 15.80 20.82 17.49 20.27 19.46 17.85 18.66 18.24 19.13 20.68 17.92 19.60 21.12 21.43 19.22 20.39 20.22 17.39 18.37 19.81 18.42 19.64 19.11 18.30 17.75 17.69 20.34 18.73 18.69 20.37 18.51 20.89 17.72 18.90 21.14 17.34 19.37 20.84 18.95 19.52 21.14 21.50 20.73 19.03
FQTPSYTQPYQGSSVTL 12.47 13.38 13.39 11.75 12.71 13.59 10.92 12.58 11.66 13.05 12.28 15.51 11.79 11.66 12.40 11.81 12.73 14.31 13.25 13.01 14.26 14.36 14.94 13.22 13.13 14.02 14.28 11.91 13.62 14.60 11.42 12.49 12.42 13.58 12.46 15.02 12.76 10.83 11.39 11.46 12.34 13.62 13.42 12.32 12.34 12.63 10.79 14.71 11.71 15.41 11.05 13.76 10.43 12.05 12.80 12.22 12.27 14.07 15.44 16.03 14.98 12.38 13.05 14.82 14.66 11.78 8.65 14.35 15.13 12.10 12.15 12.17 11.11 14.18 13.65 13.80 13.68 14.25 13.46 10.70 12.81 12.55 10.97 10.36 14.72 14.53 11.15
DDQSAETHSHKQSRLY 17.03 15.85 15.42 16.89 17.80 18.45 18.24 15.13 16.76 16.46 15.63 15.97 15.63 16.55 15.74 15.83 15.84 12.75 16.75 14.40 16.01 17.77 15.96 17.94 16.04 10.29 15.69 17.33 16.24 16.21 15.39 15.84 15.62 16.06 14.77 15.74 15.02 15.87 15.60 15.69 17.38 15.18 17.02 15.89 18.88 17.98 18.68 17.31 17.21 15.68 17.00 15.18 17.00 16.60 17.08 15.68 16.60 16.64 16.89 16.39 18.40 17.23 17.98 13.72 18.05 19.25 18.14 17.28 18.05 16.57 17.19 14.98 17.51 17.44 18.66 18.07 17.38 17.14 16.13 16.35 16.88 17.72 17.08 16.71 16.52 18.77 15.98
LSRQELFPFGPGQGDLE 12.70 10.12 11.79 13.28 10.44 9.37 12.63 12.68 12.50 12.44 11.98 11.29 12.30 11.48 11.33 12.25 12.02 13.58 12.93 11.61 12.09 11.59 11.63 13.76 11.72 14.97 11.73 10.76 11.37 11.09 10.91 13.00 11.55 12.29 11.64 12.93 12.10 12.30 11.55 12.55 10.74 13.29 10.59 12.23 13.83 12.97 12.86 13.03 12.11 13.62 12.13 13.18 13.12 13.09 13.00 12.60 11.36 12.03 10.38 12.72 13.49 13.10 10.99 12.22 12.50 11.18 10.73 12.88 13.80 12.75 12.51 12.85 12.19 11.68 12.55 12.48 13.20 13.11 10.02 10.53 13.96 11.81 12.36 11.07 12.34 12.55 12.17
DEAGSEADHEGTHSTKRG 17.04 19.41 16.13 19.40 19.23 19.73 19.64 19.87 17.71 18.04 18.22 17.61 18.80 19.71 16.79 19.48 20.08 10.89 18.06 21.17 15.82 14.99 20.25 19.37 20.50 17.93 15.56 16.37 21.44 21.94 18.96 10.68 20.48 22.04 10.91 13.97 16.42 18.17 16.02 20.54 20.26 21.23 18.19 11.99 20.10 17.36 20.49 18.83 18.35 18.37 19.29 17.71 16.98 17.43 17.71 18.53 18.23 17.87 15.37 16.97 18.38 19.68 18.87 14.19 18.84 18.05 21.24 20.48 15.72 15.72 20.39 14.90 18.19 17.54 19.46 15.79 19.52 21.45 16.73 14.10 16.81 21.14 19.90 18.64 19.62 17.81 18.57
TTTPSKQSNNKYAASSY 14.89 15.97 12.24 16.39 15.97 16.91 16.81 14.71 16.11 15.09 15.29 16.10 15.31 16.25 14.46 14.87 15.21 13.78 14.59 14.56 14.63 13.84 16.07 15.37 15.26 14.70 14.94 15.56 15.27 13.63 15.84 16.06 15.00 16.40 12.14 12.17 13.97 15.33 13.71 14.60 14.64 15.29 14.85 13.80 14.38 15.49 17.21 16.16 15.31 15.92 15.99 16.09 14.80 13.42 14.50 14.98 15.16 15.74 14.09 14.38 15.53 14.38 15.20 13.84 15.01 15.78 15.50 14.68 15.53 16.10 14.53 16.14 16.02 15.12 15.57 15.53 14.71 15.18 12.70 15.66 15.80 14.26 14.74 16.08 15.48 12.77 15.77
LWVGTGASEAEKTGAQEL 10.25 9.32 13.95 11.01 11.36 12.16 12.91 12.36 8.13 13.00 13.08 11.75 13.26 11.98 12.95 12.58 12.44 7.68 12.18 10.39 10.36 13.18 12.55 11.66 11.20 12.16 7.22 13.82 12.81 10.02 13.45 13.55 12.81 11.65 13.35 13.07 13.74 11.99 10.82 11.48 12.76 10.40 12.92 13.16 12.68 12.79 10.90 12.86 12.83 7.35 11.78 9.53 12.33 9.82 12.37 12.37 12.84 12.33 12.16 11.54 13.10 9.53 13.42 14.00 13.73 13.15 9.10 13.32 12.79 9.65 12.87 13.25 10.41 12.46 11.11 13.30 9.93 10.91 10.77 13.45 11.18 12.44 11.01 10.79 12.49 11.99 11.29
VSWVPPPAENHNGIIRG 13.87 14.08 13.33 13.11 13.92 12.60 13.75 12.81 15.01 14.50 12.59 14.79 13.86 12.81 12.44 15.45 12.78 13.51 13.16 11.60 14.17 13.19 13.23 13.48 14.59 14.57 15.41 16.31 13.95 13.43 11.59 13.97 13.05 12.26 15.13 13.01 14.29 14.23 12.06 14.19 13.66 13.81 14.49 14.36 14.00 15.39 13.27 14.40 14.99 14.95 14.27 14.98 15.56 15.87 14.42 15.20 14.95 14.43 14.38 14.80 13.94 14.89 14.00 13.19 13.17 14.14 16.65 12.93 14.71 15.03 16.28 15.00 15.18 16.47 14.69 15.62 15.73 15.20 14.86 15.00 15.19 15.22 14.65 14.73 13.54 14.45 15.49
FRVVAQGVGIPEDSIFT 12.90 13.30 14.77 13.43 13.69 13.62 14.11 10.40 12.08 12.21 16.95 11.57 13.58 10.77 13.24 12.38 12.96 14.05 14.20 11.64 12.50 12.77 13.46 9.87 14.46 10.42 13.09 16.42 14.06 11.03 14.25 14.37 13.49 14.25 14.02 13.11 13.79 13.82 13.89 13.00 10.20 14.14 13.55 13.53 13.90 14.99 13.12 13.22 14.30 14.53 14.01 12.84 13.64 14.50 14.76 13.72 11.80 14.25 13.24 14.79 11.21 14.96 14.82 13.10 16.60 16.54 8.11 15.13 15.15 14.14 13.80 14.04 12.45 11.81 11.12 9.76 11.90 13.86 14.85 14.60 14.70 12.76 12.87 15.23 13.03 11.86 12.06
LQDFRVVAQGVGIPEDS 11.73 10.34 11.93 11.09 9.92 12.49 7.59 11.33 12.79 12.43 14.33 15.53 10.55 11.63 11.66 11.29 13.19 12.20 13.77 8.58 12.24 12.27 7.63 11.85 12.63 10.57 12.52 13.22 13.13 10.94 12.90 11.95 12.47 14.06 13.62 14.16 13.02 10.28 11.48 13.09 13.22 12.07 13.81 9.50 9.24 12.34 16.48 11.77 10.05 13.92 12.27 14.50 11.94 12.12 12.82 12.90 10.63 13.40 15.12 12.91 12.74 9.49 13.63 13.36 13.37 12.82 12.89 12.92 13.00 13.72 13.29 14.11 13.94 12.68 9.89 14.25 11.35 13.87 12.67 14.55 10.35 10.71 12.58 14.34 12.29 14.11 9.75
TGYQVDKNKDDELTGF 13.93 14.67 14.90 14.41 15.17 14.21 13.96 12.94 15.41 14.12 15.54 11.83 14.23 14.80 15.11 14.84 13.96 14.53 14.75 14.17 15.45 14.40 16.65 14.08 14.30 13.36 13.38 14.45 15.45 13.88 14.46 14.16 14.94 13.99 15.49 15.81 14.57 15.15 15.28 14.24 13.79 14.47 13.62 14.93 14.67 14.93 14.04 13.90 14.02 14.76 15.13 14.01 17.76 13.78 15.51 14.98 15.09 13.49 14.42 14.32 14.51 15.59 14.16 12.84 11.77 16.25 14.27 14.82 13.54 15.01 14.37 14.42 15.49 15.29 15.52 13.57 13.90 14.96 14.75 14.87 15.00 14.07 12.15 14.49 14.37 13.36 12.93
DEAGSEADHEGTHSTKR 15.22 16.98 12.20 15.12 17.44 12.17 16.92 17.35 12.73 13.98 16.32 14.47 16.44 16.05 14.83 17.20 17.33 14.56 17.30 17.58 13.30 14.35 13.42 14.70 15.68 15.76 13.83 15.97 15.88 17.35 14.70 18.09 16.75 17.11 13.74 13.96 11.73 14.26 15.36 13.80 15.02 15.31 13.75 14.06 16.48 15.61 15.51 15.25 15.75 15.17 16.88 15.33 15.18 14.07 15.64 15.92 15.57 14.93 13.03 13.65 15.89 10.35 14.34 14.71 17.33 16.64 17.47 15.26 12.02 15.53 15.43 15.54 14.64 13.98 14.82 15.56 15.52 15.19 15.69 16.26 16.82 13.96 15.15 16.31 11.34 15.54 15.64
VSEDPINDGEWHRVTA 15.79 15.71 15.12 16.54 15.33 15.11 15.82 18.63 15.48 16.81 16.25 16.22 16.83 17.08 16.14 18.13 16.26 11.97 16.29 17.65 16.23 15.64 16.99 16.84 17.27 15.32 12.89 15.83 16.38 16.36 17.08 16.42 17.52 18.13 16.28 16.91 17.08 17.72 15.99 16.53 16.40 17.06 15.90 15.82 18.51 17.83 18.52 17.66 17.44 17.13 18.02 14.77 15.28 18.23 17.63 16.02 17.14 16.09 17.46 16.96 17.88 16.29 15.74 15.53 13.75 14.82 15.98 17.57 16.50 19.02 18.80 16.52 16.03 15.89 16.21 15.34 16.55 17.35 17.37 16.23 18.77 17.00 16.25 18.23 16.17 16.13 17.57
Q(-17.03)GQYDLDPLPPFPDHV 13.00 11.21 12.08 11.76 12.84 11.63 12.73 13.69 12.90 14.24 11.60 14.12 12.90 11.45 13.29 10.27 13.56 12.77 13.27 12.74 11.99 12.47 13.15 13.52 12.76 12.97 13.39 12.72 13.30 12.99 13.07 13.19 12.85 12.37 11.35 12.77 11.91 13.26 13.83 13.31 13.29 12.56 14.08 12.41 13.68 13.16 13.61 14.05 12.92 13.98 13.16 14.39 13.37 14.22 13.33 12.67 12.95 13.07 13.86 11.91 12.87 14.23 13.93 12.98 12.35 13.52 13.41 12.83 13.08 12.34 13.78 14.73 12.57 12.33 12.88 13.67 12.74 13.04 12.27 11.87 13.67 12.79 13.07 13.02 12.37 13.85 13.40
DHDVGSELPPEGVLGALL 13.36 14.67 12.65 14.01 15.37 13.50 12.85 14.31 13.52 13.14 14.18 12.92 12.29 12.57 14.37 13.68 11.04 14.46 12.02 15.61 15.08 15.29 14.09 14.01 11.86 12.78 14.70 12.33 13.69 13.59 15.47 14.71 14.54 13.13 14.29 12.56 14.19 13.19 14.16 13.18 10.73 8.96 15.22 13.36 14.62 13.02 16.90 15.58 12.88 14.61 14.73 12.56 14.05 12.63 12.31 12.77 13.67 11.09 14.51 12.76 13.29 14.10 15.20 12.55 14.46 13.53 14.65 12.85 10.04 15.90 15.29 14.95 13.42 12.65 15.13 12.20 14.30 13.42 15.48 14.52 11.29 12.13 13.69 12.90 13.25 14.87 13.01
LREGRRGSIQVDGEEL 15.54 13.89 14.57 14.24 13.67 15.04 14.60 15.96 15.11 15.38 15.91 14.62 13.45 14.41 13.08 13.30 15.15 14.47 13.04 14.38 13.85 14.16 13.33 13.55 14.30 15.14 14.88 15.89 14.07 14.03 15.08 15.04 15.44 15.58 15.58 15.14 14.76 14.91 14.23 15.78 13.70 12.91 14.60 14.86 15.46 17.64 13.82 13.98 16.60 17.00 16.42 15.28 14.35 17.88 13.35 15.23 14.35 13.95 14.35 12.48 14.62 15.17 15.79 13.43 14.61 15.72 16.10 15.26 14.17 14.56 15.77 16.89 15.26 15.92 14.87 11.26 15.50 15.45 13.53 14.79 15.23 15.48 13.23 16.34 12.25 12.69 14.32
DVQNVAAAPELAMGALEL 10.58 13.09 10.37 12.32 11.36 12.62 12.21 12.98 12.06 13.44 13.52 11.87 13.39 12.24 12.82 12.03 12.69 12.80 11.66 12.30 11.95 12.91 13.43 13.63 12.06 13.99 11.99 11.52 10.95 11.13 13.27 11.73 11.98 12.01 13.58 13.53 13.50 12.58 12.55 13.04 13.36 11.29 14.30 13.17 13.08 12.55 10.52 9.58 12.41 13.07 13.36 12.37 12.09 13.50 13.22 12.71 12.54 13.26 13.18 11.89 14.07 10.87 12.56 13.48 10.49 12.30 10.38 13.33 13.18 12.10 13.47 14.14 13.38 13.79 13.69 12.09 8.20 9.94 14.39 11.70 11.09 9.08 11.81 11.51 13.44 13.49 12.86
VDALHEIPVKKGEGAEL 12.44 11.26 15.76 13.39 12.71 13.37 13.79 12.67 14.32 12.52 13.20 12.82 11.10 11.69 12.42 12.72 13.64 13.30 11.75 13.11 11.36 10.69 13.00 12.90 11.91 13.21 12.11 14.12 13.54 13.93 9.63 12.35 11.15 12.01 12.33 14.41 12.28 12.27 14.93 13.42 14.43 13.23 12.21 12.74 13.75 13.85 13.56 12.14 11.87 13.01 13.15 14.05 13.93 12.99 13.63 14.41 12.47 13.42 13.35 12.14 12.22 12.18 11.96 15.69 13.71 14.40 13.25 11.25 13.24 13.94 14.65 14.71 12.88 12.01 12.47 14.78 13.45 13.41 13.94 13.48 12.25 13.76 13.23 12.64 14.66 14.93 15.01
EEAPSLRPAPPPISGGGY 12.82 13.02 13.09 14.99 11.84 13.65 14.05 12.18 11.70 12.23 14.09 12.30 10.92 13.57 12.45 13.09 12.52 13.07 11.12 13.91 10.87 11.56 12.97 12.76 13.09 13.80 12.30 14.23 11.65 12.17 12.82 12.75 13.26 12.82 11.38 13.22 11.78 12.73 13.36 13.32 13.68 13.09 12.30 13.98 13.86 14.14 12.82 14.67 12.30 13.52 13.20 15.25 14.96 13.06 13.54 12.54 12.44 12.76 13.94 12.77 13.70 13.34 13.58 13.29 13.54 14.38 14.91 12.98 13.22 13.98 16.04 14.87 13.21 11.60 12.22 14.54 13.96 13.38 13.75 13.15 14.11 13.15 12.98 10.69 13.68 14.42 14.20
S(+42.01)SYQQKQTFTPPPQL 11.81 14.49 13.80 12.96 11.89 11.37 12.44 9.29 15.24 9.29 12.69 10.59 12.91 8.40 12.57 12.77 11.74 13.50 10.37 9.42 13.21 13.32 12.49 11.00 10.66 11.11 12.87 11.10 11.83 12.85 12.61 10.72 11.36 13.08 12.80 12.90 9.49 11.04 9.49 13.82 10.06 12.77 11.71 13.57 15.35 8.83 11.69 10.16 13.15 8.71 12.01 7.78 14.48 14.16 12.95 12.48 13.96 12.07 14.88 11.67 11.64 13.37 11.22 13.04 11.62 12.28 10.59 12.95 13.09 13.33 10.01 13.55 13.96 13.03 12.57 11.46 12.02 11.66 12.57 13.15 10.86 12.92 14.07 12.04 11.97 10.84 12.38
YKAIPVAQDLNAPSDW 13.21 11.82 13.72 11.62 11.63 13.51 14.90 12.56 8.75 12.32 11.90 13.13 13.85 12.02 11.47 12.55 12.09 13.41 12.13 11.37 11.63 11.50 13.38 13.05 9.31 13.68 11.54 12.10 11.98 10.65 13.28 11.81 10.01 11.65 11.56 12.91 12.20 14.90 13.25 12.50 13.54 12.45 12.09 12.27 13.08 13.38 12.47 12.73 11.83 13.27 11.51 15.01 14.06 12.89 12.00 14.46 12.01 11.52 13.63 11.99 12.67 12.12 13.36 15.10 13.30 14.08 13.55 13.27 13.57 13.36 12.32 12.07 13.26 12.31 14.04 13.65 13.78 12.50 10.48 13.37 13.88 12.53 12.91 11.24 14.61 15.33 10.12
EVDETYVPKEFNAET 13.87 14.50 15.37 13.75 13.19 11.82 12.72 12.36 13.56 7.63 9.87 12.33 13.03 10.80 14.10 13.33 12.56 13.67 14.34 12.78 13.46 14.21 13.27 12.99 12.36 9.51 9.55 9.35 11.97 13.30 13.40 12.47 13.61 12.71 14.24 14.03 13.54 12.26 13.76 13.24 9.48 10.86 10.95 15.65 9.23 13.28 12.70 11.84 14.19 6.73 13.75 13.40 13.11 14.47 12.39 14.12 15.32 14.65 13.29 13.63 13.79 12.58 14.39 15.71 12.39 14.36 13.48 11.52 12.93 13.29 14.35 12.68 12.67 13.39 12.45 12.09 12.03 12.68 14.40 14.77 13.65 14.04 13.86 12.11 13.85 13.70 13.46
EVQVFAPANALPARSEA 13.70 14.47 13.29 15.18 14.23 14.35 15.40 13.22 14.24 14.80 14.36 15.19 13.09 14.04 12.59 11.97 12.77 13.62 13.63 12.89 12.72 12.11 13.57 14.08 12.89 13.45 12.26 13.34 13.45 13.56 16.25 14.03 13.95 14.29 10.50 11.58 12.51 15.82 13.63 12.86 15.25 12.73 11.85 11.54 13.78 13.58 14.41 13.30 12.01 13.32 13.25 13.99 13.16 15.10 13.26 13.66 14.51 13.37 14.50 13.07 14.15 14.10 14.54 10.44 14.12 13.93 13.38 13.11 12.36 13.68 13.90 13.26 14.35 14.10 13.58 10.77 13.04 14.93 12.75 13.16 14.48 12.64 12.42 13.53 14.37 12.66 13.27
SVIDQSRVLNLGPITR 14.42 15.54 15.19 14.92 15.38 14.29 12.90 12.87 15.33 16.00 13.80 13.87 10.78 14.77 14.97 14.34 14.29 16.27 13.30 15.93 15.36 15.69 15.65 12.29 17.14 11.75 15.89 11.74 13.42 13.61 14.82 15.61 15.09 11.80 16.20 15.09 15.21 15.46 15.04 13.03 14.33 15.65 14.11 15.66 10.96 14.11 13.76 13.94 15.88 14.99 14.03 13.94 15.47 16.29 16.60 15.33 16.60 15.91 16.81 15.60 16.10 17.55 15.08 16.34 14.79 13.55 14.42 16.88 13.19 16.35 13.60 14.51 15.55 14.15 15.87 13.58 14.69 14.78 17.24 16.68 16.26 14.66 15.33 15.57 15.47 16.06 15.26
SGSVIDQSRVLNLGPIT 16.78 15.74 14.08 15.90 17.43 16.95 16.78 16.59 16.01 16.23 14.93 16.39 16.61 17.06 16.43 16.35 15.39 15.17 15.93 15.35 16.99 16.20 15.41 16.02 18.07 15.80 17.08 15.50 12.43 15.86 14.43 15.30 17.04 14.52 14.49 14.71 14.33 16.32 13.10 16.90 17.13 15.20 16.24 15.42 16.80 17.04 17.41 17.42 15.88 17.07 16.90 17.70 15.32 17.29 14.88 17.03 15.68 16.81 14.83 17.56 17.07 18.20 17.58 14.68 15.61 16.89 16.42 16.55 18.33 15.75 16.15 15.29 17.00 18.57 16.86 14.03 18.12 13.97 16.27 16.67 17.54 18.16 15.84 15.90 14.82 16.12 17.70
YADKPETTKEQLGEF 15.30 13.30 13.76 13.93 15.75 14.80 14.69 13.97 13.96 13.72 16.19 16.45 15.03 15.90 16.34 16.76 13.99 13.51 15.29 14.33 15.42 13.62 15.54 15.86 14.02 14.48 11.92 14.48 15.06 14.15 17.27 15.00 17.09 14.92 17.14 14.57 16.20 15.77 14.46 15.20 12.27 14.14 15.46 15.25 12.91 13.71 14.56 14.62 9.72 15.66 14.24 14.22 17.11 15.11 16.51 16.37 13.81 15.06 14.63 15.09 15.45 14.44 14.97 13.88 11.83 15.50 16.01 15.61 14.32 19.14 16.12 14.61 16.59 10.84 15.07 14.28 13.23 16.57 14.84 16.70 13.76 15.17 13.63 12.95 15.18 15.05 14.83
VVENGESSQGRFSVQM 11.04 13.89 13.42 12.11 12.79 11.86 14.14 12.96 13.31 13.64 12.92 12.79 11.65 12.51 13.87 11.80 10.47 13.13 12.11 13.83 13.67 14.36 14.53 12.44 11.42 12.84 11.81 10.54 13.78 15.00 13.57 12.91 13.41 14.08 13.51 13.15 14.59 12.52 13.44 13.22 12.76 13.21 14.04 12.58 13.53 12.04 17.17 13.65 11.75 13.01 12.05 13.53 14.93 13.61 12.66 12.53 12.77 13.30 16.16 12.75 13.01 13.41 13.11 12.17 14.33 13.42 10.05 13.47 12.72 13.84 11.17 12.19 12.76 11.62 12.65 11.56 12.35 13.50 14.52 13.88 14.58 12.84 12.59 12.83 13.32 13.92 13.31
VVSLGSPSGEVSHPRKT 14.30 14.32 14.47 13.09 16.39 14.41 12.20 10.29 13.63 14.38 15.41 14.65 13.31 13.07 11.81 13.39 13.61 15.92 13.26 12.26 15.53 14.88 11.62 13.23 14.30 14.50 15.18 11.35 14.02 12.50 14.03 17.39 15.60 16.11 14.45 15.27 13.99 13.37 13.97 10.83 11.19 12.82 13.32 15.12 14.74 15.32 14.85 12.72 15.49 12.58 16.26 13.04 14.46 15.72 12.56 14.74 14.77 12.99 14.51 15.53 13.97 15.03 10.89 14.14 14.54 14.93 15.61 14.48 13.25 16.72 16.06 14.87 12.99 14.97 12.17 14.01 14.38 13.31 14.37 14.53 12.48 12.70 12.92 15.08 14.18 13.71 14.87
IPGGLSEAKPATPEIQE 11.83 14.63 14.88 13.05 14.34 11.50 11.79 11.91 14.54 12.16 9.21 14.05 12.60 12.14 13.70 12.81 10.85 13.43 9.25 13.23 13.94 14.31 13.04 12.45 13.67 11.31 13.26 12.21 14.04 11.87 13.28 12.03 11.12 10.42 13.03 11.88 10.61 11.78 13.94 11.97 13.34 12.89 12.32 13.01 14.16 12.72 11.06 11.31 13.45 11.28 11.86 12.99 11.85 12.93 12.78 13.19 14.71 12.26 15.79 11.43 11.94 12.41 11.45 13.21 13.35 13.52 10.61 12.82 13.38 13.98 10.70 13.07 14.03 12.39 15.98 13.56 12.50 12.75 12.83 14.41 12.56 13.26 13.92 12.69 12.09 13.02 11.72
FRVVAQGVGIPEDSIF 12.82 13.96 14.13 12.64 12.37 12.78 13.79 13.06 14.62 13.15 16.79 15.37 14.31 14.02 12.81 13.54 15.12 16.17 15.63 12.75 13.01 12.32 14.51 14.52 11.25 14.01 13.38 17.13 10.88 13.38 15.74 15.47 14.79 13.65 14.51 16.06 13.49 15.42 14.82 14.16 11.69 14.21 13.12 14.81 15.16 14.69 14.00 11.32 13.85 15.09 13.89 14.95 15.47 15.83 15.65 15.38 14.58 15.35 15.98 15.04 13.21 16.78 13.18 14.80 9.18 11.37 12.54 16.49 16.21 15.56 17.21 16.23 14.74 13.91 15.11 14.35 14.65 14.64 7.07 14.89 15.85 15.51 14.70 15.01 15.89 14.75 14.54
VDISQDNALRDEMRA 14.05 14.92 13.27 15.05 14.21 14.48 14.63 14.80 14.85 14.88 15.22 16.00 14.85 15.32 14.21 14.32 14.60 11.35 13.27 14.19 13.60 14.47 15.04 16.01 15.87 15.43 16.51 13.90 15.06 15.11 15.60 14.49 15.75 15.01 14.90 12.57 14.70 15.50 14.78 14.63 13.43 15.29 13.88 15.02 13.44 14.74 17.65 15.67 14.18 16.16 15.01 15.50 15.72 15.64 15.85 14.97 14.66 15.50 15.14 13.51 15.99 15.51 15.10 13.64 13.38 13.61 13.78 16.27 16.04 16.19 16.19 15.89 14.98 14.83 14.59 15.55 14.19 14.48 15.31 14.66 15.79 14.14 14.98 14.83 13.59 14.21 15.02
SEDPINDGEWHRVTA 12.70 8.96 14.87 10.48 13.92 13.39 12.65 16.89 13.21 8.45 12.62 11.71 11.03 13.14 14.86 13.26 12.15 15.15 12.32 14.53 13.45 11.58 13.95 11.94 12.26 13.79 9.91 10.10 11.91 12.99 13.26 13.23 13.61 13.85 7.81 15.06 11.56 13.45 12.64 12.89 12.81 13.08 12.74 14.19 11.41 14.34 13.42 13.97 12.30 13.11 13.59 11.08 12.99 13.21 10.84 14.78 10.53 14.53 13.30 14.23 14.09 13.86 13.93 14.13 14.43 13.97 11.15 14.25 12.63 10.32 14.78 11.02 11.59 12.73 12.31 12.21 13.01 13.38 12.35 11.68 13.34 12.91 13.22 12.78 12.01 12.02 13.52
LWQGVEVGEAGQGKDF 12.90 13.59 14.11 13.79 15.29 12.92 13.81 12.43 11.41 13.60 13.18 12.63 14.55 13.03 12.87 13.64 14.68 14.91 13.68 13.05 11.46 11.42 12.54 12.96 12.86 12.17 12.31 14.79 12.76 13.76 13.98 14.40 14.96 14.43 13.80 10.46 14.53 14.15 13.41 14.01 13.08 12.80 10.16 10.61 14.68 14.95 13.51 7.99 13.92 13.93 14.13 17.31 12.45 12.35 13.97 13.63 13.64 13.82 12.45 12.89 14.70 12.18 13.65 14.39 14.30 14.36 14.17 14.80 14.25 12.79 13.94 13.55 10.71 13.25 12.63 11.96 13.57 12.29 12.86 13.17 14.42 13.37 13.82 12.97 13.16 13.05 14.12
IPVKQADSGSSEEKQL 15.12 13.28 12.40 12.78 13.68 14.31 12.68 14.54 13.30 13.31 11.05 13.08 13.75 13.51 14.74 14.65 11.55 14.76 13.48 14.71 14.20 15.26 14.69 14.47 14.29 13.49 12.10 13.75 12.49 13.82 13.21 12.11 12.16 11.74 13.56 14.45 13.61 12.91 13.33 13.26 15.15 13.19 15.11 12.65 14.69 14.77 11.84 14.18 13.95 13.65 14.96 14.71 13.52 13.11 14.72 14.16 14.40 14.45 13.70 13.86 14.37 14.96 13.07 11.19 13.44 14.37 15.07 14.28 14.85 13.09 14.02 13.57 13.33 13.74 15.92 14.38 14.24 13.18 14.81 15.13 13.01 13.69 13.96 13.48 15.13 15.39 13.36
VQVFAPANALPARSEAA 13.69 14.61 12.21 14.17 13.80 14.70 14.09 13.68 13.34 14.38 13.16 13.59 14.37 14.10 14.49 13.35 14.02 15.53 14.84 14.29 13.36 13.23 15.19 14.59 14.58 15.48 13.47 14.18 15.35 14.88 13.58 12.99 13.48 12.65 12.86 12.93 12.05 13.95 15.10 14.04 15.44 13.85 13.01 12.95 14.33 14.59 13.81 14.93 13.19 14.06 13.44 14.77 14.54 16.55 14.77 14.86 14.62 15.46 14.92 14.02 14.81 15.75 13.94 13.32 10.96 13.85 12.08 15.26 15.08 13.17 13.23 14.90 14.65 14.40 13.80 12.23 14.21 13.92 13.86 12.88 14.04 15.19 13.66 12.99 14.79 14.90 14.27
DHDVGSELPPEGVLGAL 14.58 15.39 15.20 15.39 17.56 15.22 16.75 12.74 16.13 13.02 16.94 15.72 16.30 15.76 16.66 15.22 15.05 15.32 15.01 16.20 15.23 15.07 15.36 16.39 16.19 14.61 15.07 13.48 15.78 14.27 18.08 16.03 16.98 17.07 15.01 14.93 14.89 17.01 15.21 16.13 15.45 15.51 12.88 15.49 14.38 15.21 15.24 15.46 15.09 15.51 16.77 15.70 15.37 15.75 16.23 15.96 16.17 15.60 15.07 16.39 16.05 15.61 16.10 15.21 15.28 14.25 14.56 15.82 14.08 15.43 16.46 14.90 16.26 10.75 15.50 14.63 14.77 16.94 15.57 17.80 16.74 14.73 15.08 16.58 16.09 12.36 16.10
SQDASDGLQRLHMLQ 15.25 15.39 14.02 15.58 15.19 12.62 15.38 11.24 15.17 14.64 14.53 14.87 17.03 14.84 15.69 14.44 17.46 13.58 15.03 15.69 16.11 15.44 15.89 15.61 16.35 15.73 12.98 14.26 15.82 15.03 13.71 13.40 15.24 15.28 15.94 16.20 14.22 14.81 15.11 14.04 16.23 15.79 14.13 14.00 14.19 15.61 19.03 16.29 15.96 15.65 15.98 16.31 17.14 16.41 17.08 16.32 16.02 16.09 15.29 12.73 16.12 16.26 15.06 15.88 14.72 15.65 13.56 17.86 16.78 15.69 14.55 15.51 16.24 16.62 16.55 16.28 15.91 14.08 17.79 16.12 16.38 16.08 15.85 14.40 14.68 16.37 16.22
YRITEATKTVGSDTF 14.57 13.61 11.66 10.50 9.73 15.09 14.31 16.46 15.91 14.58 14.44 14.36 14.86 13.55 15.59 14.15 13.79 13.99 14.15 14.21 13.21 13.36 13.25 12.98 15.02 13.86 15.04 15.33 13.72 14.49 13.39 13.53 13.67 14.05 16.14 13.29 14.05 13.55 14.20 14.45 14.96 15.51 12.63 14.89 16.42 15.89 13.75 14.91 15.54 15.58 15.42 16.06 17.60 14.80 16.18 15.90 13.45 16.09 14.64 15.23 15.01 13.56 15.76 14.58 14.22 15.85 16.08 16.15 15.75 14.36 13.72 14.97 15.66 15.01 16.03 14.28 15.52 15.99 15.55 14.76 14.08 15.61 16.17 17.09 16.22 16.56 15.84
NKEIPAWVPFDPAAQ 14.95 11.42 12.50 13.31 14.19 10.91 13.83 15.67 13.06 14.40 12.15 15.72 13.47 14.18 13.55 12.25 10.64 17.25 14.13 12.81 12.40 12.10 12.83 15.53 12.88 12.92 15.97 15.69 11.45 11.93 15.15 16.04 14.31 12.61 12.45 14.54 12.72 13.49 12.75 13.55 11.71 13.82 14.57 11.61 11.43 13.32 15.09 13.29 14.74 14.14 13.04 14.22 14.04 15.54 13.24 14.28 14.02 12.75 16.14 12.88 15.75 15.62 11.64 13.20 14.63 13.66 12.81 14.26 14.51 14.27 13.39 15.06 15.11 13.45 14.15 13.75 14.76 12.53 12.65 15.09 10.34 14.31 12.50 14.53 14.62 14.25 13.84
VIDQSRVLNLGPITR 13.34 15.22 16.91 14.19 14.56 14.79 11.00 13.59 16.28 16.16 16.04 13.24 13.60 12.62 15.47 13.43 13.53 15.83 12.84 15.05 14.06 13.75 16.17 14.26 16.14 15.06 15.46 13.23 14.97 13.11 17.22 12.44 13.71 14.09 14.70 15.97 14.04 16.12 16.42 13.96 12.79 15.51 16.12 14.98 16.86 14.39 13.43 15.17 14.34 17.09 13.67 16.35 18.18 15.02 18.26 15.61 15.34 15.22 15.21 17.36 15.36 16.21 16.88 15.08 16.90 15.30 13.72 15.84 15.23 17.28 15.22 17.71 15.96 13.12 14.81 12.97 12.60 16.09 16.92 16.72 15.70 14.70 13.11 13.78 17.66 15.84 14.81
DEAGSEADHEGTHSTK 14.23 14.72 13.29 15.72 13.25 13.37 14.72 14.21 12.91 14.91 16.33 13.90 13.82 15.59 15.37 10.48 14.69 10.65 15.34 12.93 14.10 14.06 12.56 12.98 13.74 13.87 14.87 12.64 14.69 14.01 14.43 13.86 13.19 13.89 14.39 14.25 13.41 13.68 14.46 14.12 15.34 13.97 14.41 14.13 13.33 14.25 16.81 15.66 15.39 12.54 14.73 13.03 13.07 10.00 13.70 15.77 14.64 15.33 12.84 13.65 14.89 14.31 14.89 13.70 15.09 12.88 13.79 14.05 14.63 14.45 14.44 14.27 14.64 14.86 14.61 17.16 11.63 13.79 14.98 14.50 14.79 14.34 13.67 15.25 13.20 11.24 15.43
DAPGQYGAYFHDDGF 15.99 16.69 14.92 17.98 18.37 16.34 16.53 16.25 16.38 15.47 17.06 16.63 17.60 17.84 16.42 18.00 14.19 16.00 16.82 18.08 16.64 16.29 17.08 17.27 18.57 14.94 13.05 15.60 16.33 16.82 17.38 16.59 17.84 18.79 16.29 14.14 15.47 17.70 16.11 16.22 16.04 16.56 13.01 16.52 16.94 18.03 15.46 17.66 16.92 16.85 17.90 15.98 16.25 17.15 17.87 16.63 17.44 17.32 16.48 16.50 17.46 16.53 16.90 16.38 15.11 15.25 17.41 17.57 16.39 17.99 18.52 17.13 15.42 16.30 16.04 14.41 16.89 17.48 17.36 16.85 18.47 16.82 16.63 17.29 16.46 14.94 16.80
SGSVIDQSRVLNLGPI 16.80 14.14 15.43 13.30 17.38 15.27 14.07 13.47 15.41 14.98 13.99 13.54 14.10 16.92 15.79 13.48 14.29 15.28 15.46 15.11 16.50 15.86 14.41 13.90 13.97 14.99 15.77 14.88 11.17 13.73 13.79 15.70 16.14 15.87 16.68 13.69 16.05 15.01 13.20 14.42 13.11 15.31 13.10 15.85 13.85 16.59 15.46 17.22 15.45 16.83 14.06 15.02 7.44 18.08 14.60 15.20 12.86 15.92 14.16 17.31 15.92 17.31 18.49 13.95 12.26 14.10 16.75 14.79 17.35 14.92 15.81 14.03 14.41 16.29 15.27 18.20 16.52 12.70 16.92 16.11 13.45 17.47 13.36 14.61 13.64 16.00 16.49
VKVWPQQPSGELFE 13.76 13.53 14.89 13.57 13.00 14.39 13.99 12.50 12.71 11.69 13.36 14.22 12.69 11.81 11.34 11.41 14.45 15.08 12.69 10.82 12.53 15.62 10.45 8.84 10.77 14.65 15.34 14.95 14.80 14.51 13.67 16.70 16.19 14.14 13.76 15.31 13.40 11.70 11.10 11.87 12.54 11.69 11.64 14.71 12.00 15.38 14.42 13.07 14.74 13.38 14.97 11.98 13.21 10.23 12.77 12.64 13.87 13.19 13.85 14.04 13.29 14.20 16.51 15.16 15.61 10.99 12.04 14.63 14.01 13.36 13.57 13.85 12.46 13.27 11.11 14.91 14.30 14.68 10.72 7.14 12.95 13.91 14.60 15.78 11.43 12.74 13.28
VQVFAPANALPARSEA 15.46 16.12 13.43 16.35 15.73 16.46 16.73 15.55 15.47 16.50 15.53 16.03 15.78 15.99 15.24 15.24 16.25 16.50 16.30 15.56 15.58 15.45 14.74 16.32 15.59 16.35 14.21 15.72 16.37 15.77 16.36 15.58 15.51 14.89 13.61 15.07 14.16 16.70 16.39 15.66 16.87 14.88 14.59 14.14 15.92 16.21 16.04 16.11 15.32 15.95 15.88 14.09 16.18 16.85 16.21 16.49 16.62 16.71 16.28 15.66 16.23 16.80 15.84 13.69 13.53 15.87 14.53 16.07 15.68 15.88 15.14 16.62 15.77 16.20 14.97 14.72 15.62 15.93 15.20 15.51 15.39 16.51 14.99 15.39 16.04 15.95 16.28
VSLGSPSGEVSHPRKT 15.08 14.52 13.86 14.84 16.09 12.41 12.12 15.13 12.99 16.23 13.47 15.10 15.57 16.37 15.61 15.01 15.01 17.78 14.58 13.79 17.02 16.26 14.76 16.06 17.74 13.76 10.61 13.46 12.13 16.22 14.27 18.05 17.02 18.20 14.15 16.21 14.48 12.40 12.95 14.74 15.31 13.90 15.62 13.56 15.81 16.64 17.14 17.20 16.48 13.60 17.58 12.92 13.96 17.17 15.34 15.97 17.47 16.23 14.66 15.66 16.55 16.85 12.31 18.27 15.78 16.49 16.21 13.39 16.18 16.42 16.64 15.90 15.35 15.99 15.43 15.90 16.63 15.04 13.27 15.41 17.23 15.82 17.15 13.97 12.62 14.19 15.74
AKADAAPDEKVLDSGF 13.83 13.33 13.53 12.96 14.11 14.12 14.47 14.96 12.34 15.11 13.30 13.26 12.84 13.01 13.73 15.39 13.36 14.80 14.63 14.75 14.85 11.68 15.49 15.06 13.18 15.19 15.44 5.66 14.05 14.28 13.29 13.67 12.28 12.36 13.35 13.42 13.23 14.30 11.04 14.70 15.36 14.82 12.11 13.62 15.27 14.53 13.59 14.56 15.16 14.28 14.25 13.43 13.57 10.96 15.16 15.30 13.48 14.49 14.25 14.83 14.62 13.33 14.28 13.11 15.99 14.28 13.73 13.68 15.47 14.77 15.67 13.79 14.67 14.41 14.37 14.00 14.71 14.38 14.35 15.47 15.34 8.14 13.93 13.86 15.31 14.90 14.81
VVVHAGEDDLGRGGNQ 12.52 13.61 14.20 9.86 12.76 11.81 10.05 11.79 13.71 12.68 12.00 13.62 10.85 12.06 13.38 11.25 12.37 13.11 11.99 12.15 11.80 13.59 13.04 12.88 13.27 13.27 13.56 13.80 13.16 12.08 12.75 13.83 11.02 11.84 12.51 12.67 11.89 11.16 13.42 12.05 13.37 12.21 13.63 12.88 12.85 13.11 16.75 12.66 13.11 12.20 12.17 14.16 11.41 13.46 12.96 12.81 13.65 12.67 16.29 11.64 12.82 12.83 9.77 9.67 14.17 11.98 11.94 12.20 12.77 13.50 12.72 12.78 14.96 12.24 14.64 13.17 13.20 10.60 14.42 15.29 13.68 12.79 12.83 13.76 13.76 12.72 11.05
ANYPDLPSAYQPGIL 13.14 12.82 11.66 13.38 11.79 13.58 13.76 12.99 13.40 12.55 13.18 13.78 14.10 12.98 10.66 11.94 12.94 12.48 13.12 12.23 11.17 12.02 13.90 13.39 12.50 13.48 13.50 12.65 13.47 12.11 13.69 11.69 12.00 11.29 10.27 13.93 9.97 13.04 13.19 13.20 13.17 13.60 12.14 11.93 13.40 13.95 10.91 14.17 12.36 11.71 12.76 13.37 13.82 12.10 14.07 12.36 13.31 13.33 13.88 12.59 13.83 14.28 13.58 13.29 12.92 12.52 10.72 13.43 14.23 12.24 13.28 13.88 13.30 13.04 13.01 12.94 13.67 11.66 11.59 11.39 12.78 12.50 12.20 14.01 12.56 11.88 13.22
VGGGEQPPPAPAPRRE 16.44 17.53 16.18 17.75 16.26 16.95 17.31 16.32 17.31 17.33 16.92 15.92 16.46 16.97 17.47 17.14 17.02 16.04 16.90 16.66 16.33 16.38 16.59 16.88 16.27 17.47 17.05 17.07 17.44 16.74 17.24 15.73 15.87 16.71 16.30 17.55 16.46 16.32 16.92 16.82 16.96 16.36 18.03 16.57 17.44 17.38 18.09 17.84 17.52 17.25 17.29 17.17 17.55 17.28 17.39 16.62 16.57 17.27 16.42 17.81 17.05 17.45 17.92 16.98 17.81 17.94 18.02 16.94 16.47 16.80 16.51 17.64 17.80 17.85 17.30 17.60 17.31 17.93 16.85 17.47 17.96 17.88 16.64 18.07 17.53 17.67 17.05
SVIDQSRVLNLGPIT 14.27 14.15 12.27 14.15 15.54 13.47 13.30 13.64 13.26 13.95 11.58 11.36 12.65 15.31 13.41 12.59 13.14 14.38 14.06 15.43 14.59 14.66 11.77 14.71 14.47 12.94 14.74 12.87 14.20 10.96 15.07 15.33 13.62 14.26 13.91 13.51 13.97 13.35 14.12 13.36 11.58 13.67 13.80 14.02 10.74 13.05 14.47 14.15 14.96 12.87 13.22 10.40 13.31 15.64 11.65 11.85 12.63 14.59 13.55 12.69 13.05 13.91 14.21 13.23 13.48 15.39 14.71 11.24 14.74 11.97 12.35 16.02 13.37 10.22 11.54 17.58 13.10 14.41 15.55 10.82 13.05 12.67 14.08 9.80 14.07 9.22 13.39
IKFPEPGAIKVPEQG 15.66 15.41 15.80 14.14 14.98 14.80 13.29 14.50 19.06 13.08 14.18 12.22 14.01 15.36 13.44 14.97 14.04 15.13 14.09 12.99 11.82 13.09 17.41 14.09 14.90 16.37 14.77 14.69 12.41 13.49 11.65 15.69 13.27 10.20 11.90 13.67 14.69 15.49 15.37 14.41 15.51 14.64 16.58 14.44 16.44 11.21 15.41 11.60 15.59 13.94 14.54 16.19 15.13 13.34 14.98 17.55 16.91 12.35 16.03 17.28 13.98 14.07 14.70 14.16 16.35 17.01 15.42 15.31 14.34 13.45 13.55 12.67 19.12 16.26 16.09 15.71 16.15 13.20 12.93 16.28 14.17 18.02 14.55 18.20 14.92 16.54 16.11
WQGVEVGEAGQGKDF 12.77 13.75 14.45 12.39 14.17 8.78 10.74 11.52 10.72 12.49 13.43 12.43 13.63 11.85 13.83 13.37 14.48 14.81 13.25 12.25 13.38 11.65 10.64 13.42 10.69 11.96 13.84 14.97 12.98 13.01 13.92 14.08 14.02 13.88 12.88 12.80 13.34 13.50 9.26 12.24 12.85 12.45 12.94 11.71 13.96 14.20 13.57 11.39 13.81 14.27 13.55 14.08 14.39 14.27 10.46 13.43 14.64 9.73 10.27 13.03 13.94 11.87 12.97 11.28 11.33 14.07 15.24 13.73 13.91 13.80 12.98 12.79 12.91 12.79 13.11 17.19 13.40 13.26 13.44 13.59 13.62 12.41 8.89 12.11 12.68 11.79 13.14
IDQSRVLNLGPITR 13.08 13.23 13.85 14.55 12.49 13.52 14.46 12.60 14.77 15.23 12.90 12.84 14.27 14.27 14.88 14.87 13.51 15.27 12.23 13.46 14.50 13.86 14.59 15.21 16.11 14.84 15.15 11.91 12.80 13.62 14.01 15.79 14.62 11.91 15.45 14.71 14.06 15.10 13.94 13.41 14.87 11.58 14.68 14.79 14.30 14.47 14.30 13.07 14.93 14.63 14.65 14.44 16.22 14.87 15.58 15.62 16.71 15.02 16.29 17.38 15.19 15.84 13.76 14.29 15.15 13.54 13.23 15.72 12.52 15.90 12.28 13.51 15.68 15.35 16.60 12.84 13.78 14.97 16.69 16.01 15.36 14.31 13.81 16.34 16.09 15.13 15.67
YLAPNNLKPVVAEF 15.17 12.52 15.57 11.70 11.15 14.59 10.01 16.07 13.00 9.69 13.66 13.33 11.47 12.86 15.19 13.10 14.50 16.14 16.67 11.50 15.98 11.77 13.13 14.23 10.30 13.08 10.30 11.93 11.03 10.87 13.34 12.50 14.11 15.15 16.15 10.36 15.64 13.91 11.70 12.94 13.30 11.65 12.23 12.81 15.23 13.90 12.14 9.73 14.94 12.68 13.58 13.15 11.12 10.74 14.80 12.09 15.47 15.44 11.08 14.29 13.79 16.01 13.56 18.74 14.80 14.54 12.53 10.86 15.64 13.06 11.46 12.37 11.73 13.89 12.82 15.71 13.59 13.21 12.95 13.76 14.87 12.95 14.59 15.59 14.62 13.66 12.13
LRLPEKVPSAPPQE 13.70 14.34 13.12 13.11 14.07 13.52 14.57 13.00 14.68 14.93 11.53 14.45 13.79 13.61 13.50 15.35 14.86 14.14 12.64 13.13 13.95 13.99 13.50 13.08 14.45 14.13 15.31 15.62 13.60 13.77 12.24 13.12 12.73 14.04 14.04 13.09 13.14 14.46 13.60 13.70 14.54 14.22 15.05 13.51 14.48 14.99 13.65 14.14 15.12 14.64 14.32 13.00 14.96 15.89 13.95 15.48 14.85 13.67 15.00 14.99 13.60 13.47 14.93 15.00 11.62 13.55 14.02 14.83 14.23 15.26 14.61 15.16 15.19 16.17 14.89 16.34 15.65 14.13 15.04 13.65 14.23 13.59 14.39 15.09 14.56 14.90 15.45
HSARPGAPPPQPLDL 14.95 14.47 12.83 14.02 11.48 13.80 13.34 13.50 13.19 13.23 13.71 13.68 13.84 11.40 12.86 15.26 15.83 15.46 13.96 14.51 10.31 14.74 14.87 14.63 15.18 13.76 15.05 15.40 14.01 13.04 12.63 13.06 10.71 13.15 13.23 13.33 13.92 14.08 11.32 16.03 12.04 13.63 15.30 8.28 14.92 16.03 14.12 15.83 14.50 15.56 14.79 11.93 14.94 15.15 14.20 11.42 12.89 13.12 13.32 13.70 14.40 15.10 14.67 13.98 16.48 15.09 15.57 15.82 14.58 12.63 15.88 15.85 10.35 16.94 16.20 15.85 16.60 14.45 15.04 13.39 11.45 12.81 14.89 14.20 14.15 14.50 15.43
VAWKADSSPVKAGVE 16.20 15.54 12.55 16.50 16.20 16.77 17.72 12.87 16.15 15.44 16.81 17.64 15.77 17.01 13.59 17.16 15.09 13.69 16.08 16.85 15.62 15.75 16.55 16.78 17.45 15.47 16.72 15.46 15.01 15.00 16.40 15.73 16.07 16.72 17.05 15.54 15.95 16.64 15.03 14.83 15.69 16.81 16.08 15.75 14.54 15.81 15.51 16.96 16.13 16.65 16.53 17.10 16.04 11.40 16.80 16.13 16.06 16.37 18.04 16.20 15.70 15.94 16.34 14.09 15.47 16.02 16.95 16.10 15.92 16.48 16.15 16.07 17.51 15.88 15.90 16.85 15.50 16.29 15.43 16.96 15.74 15.98 15.44 15.86 16.05 15.03 15.91
YRITEATKTVGSDT 13.28 13.74 13.09 12.82 13.40 12.84 13.40 14.39 13.20 15.13 12.72 13.30 12.75 13.31 12.49 12.62 12.72 15.38 13.11 13.11 12.92 13.07 11.92 10.44 12.59 12.70 14.46 14.26 13.04 13.91 13.52 12.56 13.72 13.21 14.32 14.34 14.50 13.12 12.73 13.35 13.96 13.72 12.47 11.52 14.33 12.23 13.72 13.01 15.03 13.26 13.91 13.70 14.48 14.31 12.48 12.75 13.83 13.41 13.63 12.81 14.29 10.72 15.06 14.33 14.58 14.30 13.81 13.86 14.07 14.11 10.71 13.46 14.63 13.37 14.87 11.97 13.48 11.94 14.12 12.00 13.19 14.81 14.91 11.74 14.34 15.35 13.88
TWLNPDPSQKQNL 14.61 13.17 13.10 14.77 14.33 14.46 16.09 14.62 12.75 15.95 13.65 13.60 14.68 13.56 13.57 13.72 12.08 15.50 14.22 13.10 14.75 15.65 14.38 14.76 13.96 12.75 12.14 13.48 14.89 14.04 14.16 12.69 12.61 13.40 13.28 13.57 13.60 15.74 15.28 14.10 16.14 13.87 11.87 12.30 15.00 14.75 12.76 15.97 15.01 14.49 14.71 13.91 14.34 16.13 14.79 15.57 14.35 13.91 14.78 13.82 14.50 15.85 14.33 13.68 10.87 13.99 15.62 14.30 14.04 13.14 13.12 13.17 14.14 14.87 14.66 12.93 14.34 15.02 15.25 14.54 14.46 14.67 13.90 14.16 15.52 15.84 15.16
SIDWTKIEPSVNF 12.58 12.72 12.04 11.66 11.30 12.03 12.48 11.85 12.41 10.00 11.85 12.17 13.09 11.90 13.29 11.58 12.71 12.96 13.77 10.54 11.42 11.96 11.08 12.31 11.76 11.30 13.32 14.24 10.57 11.92 12.66 13.17 12.05 13.42 13.29 13.11 13.11 13.20 11.82 12.32 13.18 11.73 13.58 12.88 12.38 12.80 16.95 12.82 12.28 12.91 11.60 12.09 12.31 12.00 11.86 12.41 12.20 12.14 16.41 12.72 13.52 9.78 10.77 12.31 14.15 13.22 11.59 11.39 13.87 13.97 12.75 13.91 12.53 12.50 12.05 13.33 13.50 9.34 9.55 13.85 14.17 13.12 12.50 14.15 11.53 11.98 12.56
IEVDGRVYHVGLGD 11.88 12.92 13.00 12.92 13.92 10.98 10.08 12.84 11.91 13.52 15.01 12.55 14.12 12.14 11.94 7.98 12.04 12.29 12.85 13.38 14.75 16.05 13.95 12.96 13.68 12.27 14.49 11.04 13.17 11.31 13.16 12.94 10.49 12.54 13.57 13.15 14.24 13.07 13.03 13.78 13.26 14.31 16.50 12.15 12.62 11.84 16.43 14.40 12.29 12.92 13.24 17.65 15.84 11.10 14.22 13.17 12.34 12.95 16.22 13.49 10.69 13.42 11.72 13.33 14.05 11.86 14.50 13.28 12.74 15.95 13.50 13.95 13.01 10.98 14.07 12.16 12.98 13.65 15.40 13.67 14.01 12.05 12.90 13.66 13.74 14.49 12.96
YQAEWDDYVPKL 11.87 13.86 13.27 12.59 10.45 12.11 6.71 11.43 14.22 11.98 12.79 13.57 13.13 12.92 13.04 11.66 11.95 13.31 11.51 13.67 11.81 13.71 13.78 13.31 13.03 11.22 13.31 13.46 13.28 12.72 11.79 13.27 12.70 12.88 13.09 13.14 12.99 12.83 13.23 14.54 12.80 12.83 14.06 13.65 14.29 12.14 12.25 12.38 13.64 11.69 12.01 11.98 15.00 14.58 13.88 13.04 13.51 13.64 15.21 12.50 13.37 13.81 11.75 14.39 10.64 14.39 11.62 14.01 12.41 12.64 11.32 12.81 12.96 12.28 14.06 15.74 12.54 12.73 14.50 11.72 13.78 12.75 13.65 13.88 13.17 11.10 13.52
VIDQSRVLNLGPIT 11.37 7.25 12.92 13.03 13.35 12.28 11.77 12.41 13.22 13.01 12.69 11.33 11.44 12.83 12.84 12.68 12.13 11.16 13.11 14.00 12.71 12.62 11.13 10.84 11.28 13.47 13.50 12.18 12.53 12.39 10.54 13.53 12.10 13.75 12.69 13.20 12.52 9.74 13.47 11.90 7.54 12.17 13.79 12.77 8.87 10.77 13.33 13.31 11.78 13.07 10.28 12.35 12.24 12.87 12.38 10.87 10.87 13.51 11.20 14.05 12.00 13.61 15.04 10.27 11.62 11.83 11.56 12.92 11.88 11.89 12.94 11.07 11.98 12.85 13.04 14.63 12.41 13.02 13.12 9.04 12.48 12.18 13.53 13.15 13.11 12.48 11.73
ISQDNALRDEMRA 12.77 12.78 10.86 14.41 13.41 14.36 14.61 13.59 14.56 14.25 14.61 14.57 13.59 14.71 13.87 13.89 12.89 13.04 11.08 12.66 12.39 12.21 14.07 15.12 13.96 13.79 14.35 13.31 13.42 13.16 14.91 14.16 13.86 14.17 13.21 13.87 12.72 14.58 13.43 13.65 12.40 14.10 13.18 11.07 12.29 13.68 11.47 13.80 12.18 15.54 12.97 14.01 13.86 14.09 13.79 14.61 13.56 13.70 14.41 14.17 14.27 13.78 13.93 13.16 14.37 12.88 14.09 14.13 14.33 14.63 13.92 13.96 14.24 13.60 13.34 11.79 12.60 13.13 13.99 14.19 14.05 12.31 12.82 13.37 12.67 12.60 13.71
FDSDPITVTVPVEV 11.92 12.75 13.84 11.76 12.96 12.70 13.12 12.82 13.53 16.41 13.02 14.60 13.21 13.44 14.09 12.14 12.12 13.70 13.13 13.11 12.09 13.53 13.99 13.38 12.74 14.29 12.38 12.22 15.16 13.64 14.60 13.03 13.04 13.36 13.34 11.98 14.02 14.02 15.21 14.10 14.78 13.17 12.07 13.09 14.23 12.17 12.40 13.35 12.59 12.31 12.23 13.95 13.52 14.17 14.40 14.58 14.50 13.76 13.80 11.45 13.59 12.32 13.35 15.23 11.39 12.00 13.84 13.07 12.71 12.52 14.43 13.16 13.82 12.20 13.61 15.57 13.47 15.14 13.40 12.88 13.19 12.78 13.48 13.51 14.66 14.23 13.02
VAWKADGSPVKAGVE 13.91 13.41 13.07 13.47 14.21 13.84 13.94 15.04 14.81 13.50 13.86 13.26 13.68 13.39 14.41 14.57 13.75 13.64 13.00 13.19 15.81 16.68 12.47 14.07 14.70 13.73 15.92 12.12 12.42 12.57 14.47 14.42 13.67 14.99 14.65 13.49 12.77 14.25 12.20 13.22 12.82 14.64 15.00 13.57 14.87 12.61 13.89 14.31 12.89 14.48 14.22 12.55 14.52 13.00 14.67 13.81 14.30 13.97 14.35 14.00 13.38 13.70 14.39 12.89 15.41 13.01 14.10 13.77 13.61 14.00 13.37 13.50 15.42 13.45 14.89 13.39 13.75 13.63 14.49 14.74 13.02 12.82 14.67 13.73 14.32 14.18 12.72
PRGHSGEPGLPGPPGP 15.97 15.74 16.07 15.92 15.79 17.02 15.18 14.99 15.96 15.01 16.23 16.41 14.01 14.19 14.21 15.44 13.59 16.35 15.67 14.63 14.86 15.09 15.71 15.27 15.35 16.25 17.08 16.05 16.81 16.42 15.92 14.12 14.36 15.34 14.60 15.85 14.35 14.70 16.25 16.27 15.52 15.40 16.92 15.74 16.62 15.17 15.80 15.84 16.71 15.23 14.26 16.23 16.13 16.88 17.14 17.77 16.88 16.59 16.16 15.87 15.81 16.79 17.31 15.27 15.50 16.20 15.49 15.98 15.33 15.39 15.73 15.62 16.23 17.28 16.27 16.02 16.08 15.77 15.48 15.59 15.85 16.61 16.23 16.87 15.71 15.71 16.26
G(+42.01)DKPIWEQIGSSF 13.30 12.93 12.89 11.83 12.81 13.01 13.30 12.82 13.15 13.53 13.75 10.47 13.73 13.22 13.03 12.05 12.70 13.27 14.60 14.48 12.87 13.27 13.40 14.74 13.82 12.81 11.52 12.86 13.08 12.94 12.66 13.02 12.54 13.12 13.62 13.14 13.85 12.84 13.50 12.62 12.82 13.40 13.42 12.96 13.21 12.78 13.27 13.69 13.36 13.41 13.63 14.73 13.98 13.92 14.59 13.21 12.87 13.45 12.13 12.91 12.93 14.17 12.29 14.58 12.52 13.64 13.13 13.62 14.50 13.71 13.03 12.89 12.12 13.43 13.37 14.97 13.55 13.14 13.47 12.93 13.84 13.22 12.93 13.57 13.53 12.59 13.22
VHLTPEEKSAVTAL 11.93 13.55 16.34 16.64 15.12 16.74 14.12 16.22 13.70 14.11 14.89 13.74 15.20 14.44 17.27 14.95 13.56 11.12 14.62 15.83 14.25 14.22 13.21 13.83 14.60 12.68 15.20 16.21 15.99 16.04 12.94 11.44 12.99 13.52 14.69 11.64 13.80 13.97 17.07 12.07 13.18 17.40 10.48 14.54 16.29 14.06 16.20 16.84 18.30 11.63 16.19 10.94 14.66 16.62 15.60 13.60 15.40 14.80 16.03 17.14 16.29 16.66 13.99 23.87 16.56 15.49 15.49 14.12 12.66 11.73 16.30 17.02 18.08 18.51 14.57 18.07 16.93 13.21 14.54 17.29 14.82 15.51 24.03 18.83 16.68 17.42 16.68
WGSPAASDDGRRTL 13.32 14.42 13.09 12.68 14.03 13.49 12.99 13.33 14.04 14.07 12.29 13.58 13.80 13.72 13.76 13.96 14.32 13.78 12.56 12.31 14.74 15.11 14.15 14.24 13.53 13.28 14.74 14.85 13.77 12.53 12.17 13.20 12.40 12.70 13.62 12.79 14.42 12.72 13.90 14.06 13.57 15.68 15.65 12.56 14.51 15.13 13.44 15.28 13.61 14.77 13.93 14.48 14.27 14.21 13.97 12.41 13.99 13.39 14.91 14.15 11.35 14.60 14.42 13.54 14.22 14.91 14.28 12.98 15.25 15.60 14.72 14.10 11.97 15.02 16.09 14.14 16.47 14.06 15.66 12.18 13.39 13.93 13.59 14.05 14.69 13.77 13.10
FRVVAQGVGIPEDS 13.37 14.11 14.17 14.77 14.81 13.09 14.01 14.60 14.73 14.87 16.21 15.12 15.41 15.81 10.70 15.00 15.40 13.52 17.23 14.07 13.59 14.38 13.43 15.28 16.69 15.44 15.53 13.51 14.34 15.23 15.21 14.13 15.22 14.40 14.32 11.45 14.74 15.57 15.39 14.80 13.69 15.26 14.16 14.52 13.33 14.20 17.85 15.56 16.59 15.31 14.09 15.83 15.24 17.00 15.73 16.05 14.59 16.46 14.90 14.71 16.30 15.59 14.54 15.09 15.46 14.32 13.03 16.95 16.40 14.70 17.35 15.73 15.19 14.97 14.53 15.73 14.35 15.17 15.95 13.42 14.99 15.55 15.14 14.79 15.88 15.00 15.26
WGKVNVDEVGGEAL 12.48 13.08 16.56 13.96 13.48 12.27 12.64 13.84 12.87 11.81 11.89 13.49 13.10 13.13 13.66 12.30 12.77 14.36 12.25 13.06 9.35 15.19 10.05 14.21 13.55 12.76 14.44 13.34 13.77 12.00 9.78 14.03 13.04 14.03 12.87 11.73 10.77 11.27 14.49 13.35 13.77 15.19 11.77 14.16 14.43 12.57 11.91 15.60 14.41 12.36 13.58 12.82 14.29 14.30 14.92 12.15 13.98 12.73 14.80 14.07 13.18 13.93 14.11 21.49 15.66 12.80 14.91 10.99 10.91 15.40 12.30 14.08 13.52 14.15 11.38 17.15 13.97 13.99 13.19 13.22 14.64 14.31 20.32 16.37 13.34 15.68 14.94
DQSRVLNLGPITR 13.23 12.56 11.60 13.90 11.18 13.92 15.24 15.16 14.07 14.90 13.87 14.17 14.92 14.29 16.06 15.41 13.86 15.48 13.94 12.56 14.52 13.68 14.42 16.66 15.94 12.75 14.74 13.86 12.91 14.78 13.71 16.09 15.25 13.05 15.17 15.17 14.37 14.67 13.62 13.17 14.81 15.43 14.04 14.39 15.31 14.81 13.14 12.47 16.11 14.61 15.39 14.58 17.31 14.97 17.03 15.34 16.89 14.84 16.94 17.53 14.64 15.78 12.53 13.52 14.90 16.83 13.94 15.46 15.33 15.18 11.26 14.11 14.97 15.37 16.25 12.54 15.53 14.13 16.48 15.97 17.58 14.06 14.04 15.58 15.23 14.65 16.04
IQLQPLQEPESW 12.17 11.94 10.58 11.78 10.23 12.08 11.35 12.43 10.92 12.94 8.00 10.52 13.03 12.72 13.26 14.01 12.44 11.67 12.30 13.53 10.15 11.15 10.35 10.59 11.90 11.59 13.49 13.35 12.89 11.18 11.21 11.10 10.68 12.64 11.45 13.26 11.33 12.74 10.33 12.43 13.32 12.31 15.05 9.84 12.68 12.96 10.72 12.76 10.45 13.17 11.53 12.13 12.99 14.39 11.91 12.44 11.12 11.85 11.92 11.16 11.79 11.69 13.07 12.19 13.13 10.35 13.37 13.55 13.29 14.28 13.14 12.52 10.47 12.29 13.05 11.91 12.97 12.58 14.59 11.14 9.70 12.53 11.41 10.71 12.44 13.73 11.28
DHDVGSELPPEGVL 14.20 15.74 14.29 15.82 15.42 15.12 15.95 15.68 15.26 15.25 15.11 13.86 15.56 14.52 16.00 15.44 12.71 14.57 14.74 14.92 14.82 15.29 15.40 14.87 13.65 15.05 12.64 13.68 15.49 14.87 15.87 14.24 14.88 14.80 14.36 13.94 14.54 15.18 15.63 14.65 14.90 14.71 14.35 14.71 15.52 14.87 13.07 16.31 13.73 14.83 15.14 13.95 12.85 15.64 15.70 14.71 15.88 15.14 13.31 13.84 15.37 15.11 15.26 14.88 16.22 13.75 15.74 14.04 14.73 14.03 15.48 13.65 14.43 14.34 14.23 13.86 13.98 15.04 15.38 15.69 16.14 14.35 15.06 15.01 14.60 14.69 15.18
SQDASDGLQRLHM 15.67 15.56 12.96 16.38 11.97 15.64 16.08 16.35 14.76 13.56 13.34 15.62 16.63 15.65 15.73 15.72 15.47 15.14 13.33 15.20 16.14 15.57 15.66 15.29 15.40 15.22 12.00 14.27 15.90 15.30 14.62 14.25 16.11 15.03 15.75 11.05 15.62 15.53 14.96 15.67 16.34 15.24 14.34 14.53 15.65 15.65 16.14 16.11 16.24 15.90 16.37 16.20 15.62 16.22 16.87 15.94 16.51 15.88 14.26 14.05 16.42 15.85 14.75 14.31 16.44 15.82 14.48 16.77 16.74 15.48 14.64 14.85 15.45 15.73 16.52 12.86 15.40 13.88 17.29 16.00 16.07 14.59 15.79 16.34 13.58 16.04 15.88
IDWTKIEPSVNF 14.37 13.61 13.44 12.80 11.16 16.27 13.59 14.96 13.40 14.51 12.96 12.96 14.70 14.20 13.35 14.45 16.40 16.13 15.86 13.65 13.05 13.66 13.88 15.85 14.91 14.19 15.71 13.90 13.49 13.91 13.73 13.79 13.88 13.38 13.59 13.21 14.33 14.01 13.68 14.06 12.69 15.57 15.38 11.31 16.16 14.83 16.14 13.99 14.48 14.94 14.17 15.40 14.63 15.81 14.77 13.84 14.34 14.76 12.97 14.79 15.57 13.51 14.15 15.29 14.03 12.73 13.64 16.00 15.77 14.03 15.62 15.91 14.49 15.58 14.75 13.31 15.86 13.68 14.20 13.09 13.72 15.72 14.40 12.73 14.86 14.42 14.91
AWKADSSPVKAGVE 13.49 13.22 13.39 12.55 14.20 13.17 13.21 12.53 13.64 13.96 14.41 12.99 12.78 12.80 14.20 12.85 14.25 14.66 13.16 12.04 14.17 14.48 13.21 13.19 14.48 13.17 14.20 14.38 12.87 12.62 13.73 14.53 13.28 13.62 13.61 12.44 12.84 11.85 13.64 13.12 11.86 14.70 14.95 12.66 13.64 12.75 13.94 14.35 12.87 14.23 12.68 17.58 13.28 12.98 13.77 12.42 13.84 13.28 13.13 14.33 12.97 12.84 14.88 12.26 14.13 12.87 13.27 13.29 13.92 14.41 13.85 13.56 13.64 11.60 13.83 12.81 14.39 13.86 14.50 13.09 13.77 13.27 13.18 14.45 13.29 13.28 13.25
VNVDEVGGEALGRL 13.77 11.73 15.75 11.95 11.11 13.41 14.29 13.15 12.33 13.54 13.35 12.71 13.57 12.10 12.37 11.71 13.29 13.68 11.84 11.63 9.81 14.13 13.80 12.94 12.39 11.09 11.36 13.49 12.88 12.89 12.10 11.93 12.02 12.88 10.01 13.53 14.37 12.13 11.41 14.18 12.42 13.07 12.99 13.70 13.53 14.04 10.31 12.20 12.11 13.60 13.27 12.66 14.39 14.03 13.46 11.16 12.64 11.97 14.00 10.08 11.68 13.57 13.63 17.38 14.00 13.66 12.68 13.04 13.91 13.76 13.11 12.86 12.90 13.68 13.49 14.04 13.49 13.04 12.41 13.30 14.15 13.31 12.04 13.63 13.39 14.33 13.44
YADKPETTKEQL 13.70 13.98 14.54 15.44 14.31 12.94 14.11 13.39 13.07 12.20 14.06 13.29 13.91 13.81 13.37 15.05 14.48 10.84 14.32 13.77 14.19 13.80 12.86 13.21 13.20 14.18 15.06 14.43 14.53 14.13 13.72 13.04 13.99 14.41 16.78 13.92 16.31 13.71 14.06 14.48 14.30 13.56 13.75 14.46 14.31 13.85 13.76 15.95 16.08 13.88 14.17 13.25 15.10 15.32 15.69 13.32 14.90 14.00 13.41 16.30 13.16 14.49 15.26 13.68 14.11 14.70 15.90 13.88 13.80 15.19 14.42 14.24 15.06 14.35 14.04 13.46 14.41 15.67 14.01 14.55 15.48 14.57 14.41 15.56 13.99 14.61 14.94
TVDKSRWQQGNV 16.21 14.07 15.01 13.73 13.56 15.06 14.11 14.48 14.30 14.30 13.39 15.55 13.83 14.49 14.62 14.21 15.76 14.97 14.00 15.81 12.70 12.44 13.63 15.55 14.08 13.91 15.80 15.88 14.75 12.56 13.88 14.11 13.25 13.59 12.81 12.60 14.08 13.11 13.38 14.95 14.87 13.58 18.58 14.10 15.10 15.19 15.86 14.44 14.02 15.68 14.90 16.06 13.84 14.80 12.90 14.53 14.99 14.22 13.33 14.27 12.21 12.39 16.43 13.71 15.03 16.27 16.20 15.74 14.48 16.38 15.72 14.74 15.72 16.02 14.85 16.07 16.45 16.04 14.60 14.22 15.25 15.84 15.23 14.65 14.35 15.09 15.66
LRLTEPADTITDA 13.08 14.66 12.77 13.12 13.12 13.17 14.96 13.60 14.47 14.59 13.62 12.92 13.88 13.24 13.98 13.89 13.89 12.35 14.14 14.80 11.65 11.40 12.07 12.72 14.66 14.59 13.43 12.54 11.08 15.66 14.15 13.32 13.28 13.53 12.08 11.97 12.99 14.58 15.07 14.45 14.58 11.51 12.73 13.79 14.00 13.21 14.12 14.51 13.40 10.56 13.38 12.34 15.48 14.64 15.86 14.90 15.96 13.89 13.91 14.70 14.23 12.76 15.48 14.45 12.92 13.08 13.92 14.44 13.56 13.98 14.84 13.68 14.75 14.23 10.97 13.76 14.08 15.81 15.18 13.14 16.09 15.52 15.10 14.25 15.12 15.10 14.99
VSLGSPSGEVSHPR 15.72 14.13 12.93 13.36 14.98 14.62 13.86 14.63 9.43 15.51 13.99 14.97 15.42 16.45 14.30 14.00 14.68 15.93 11.62 13.96 15.85 14.47 13.61 14.88 15.29 14.03 15.27 13.39 12.27 16.33 13.59 17.77 16.01 17.29 15.04 15.93 16.11 13.25 13.74 13.34 15.40 14.89 15.53 13.87 13.83 15.86 15.83 16.07 16.72 14.87 17.90 13.61 15.22 16.45 13.77 13.13 16.61 15.88 15.35 16.37 16.24 14.68 13.47 15.49 15.39 15.26 15.38 16.00 14.90 15.22 15.33 14.74 14.43 15.04 13.92 12.24 16.21 16.10 15.17 13.73 16.13 15.03 16.37 15.01 14.37 11.80 14.20
DGVPGKDGPRGPTGP 15.91 16.10 15.93 16.43 15.19 15.77 15.66 16.48 16.51 15.98 16.34 11.87 15.78 15.18 12.61 16.76 14.84 14.51 16.29 16.68 15.50 14.72 16.64 14.98 15.62 15.33 16.81 15.97 16.29 16.45 16.02 15.08 15.88 16.21 15.84 16.26 17.20 15.58 15.57 16.62 15.92 15.92 16.40 16.42 17.77 16.94 16.95 16.65 16.86 16.43 17.30 15.66 17.21 16.54 16.96 17.14 16.95 16.45 16.73 16.47 15.33 16.64 16.82 15.16 17.22 16.18 17.45 15.53 15.49 16.52 16.07 15.56 16.47 16.20 15.77 14.96 16.68 17.69 15.64 16.41 17.16 17.41 16.55 17.01 15.67 16.84 17.00
AGKQLEDGRTLSD 13.18 13.89 13.56 12.96 12.97 14.31 14.26 12.46 12.48 11.79 14.34 13.59 13.91 12.89 14.62 14.19 8.92 14.02 12.27 13.15 16.20 13.06 15.24 15.08 14.37 12.88 14.41 11.97 13.88 13.43 13.37 12.60 12.62 13.96 15.07 13.20 14.69 13.35 13.86 13.02 13.74 14.77 12.76 14.29 13.66 12.89 10.77 14.60 14.13 13.71 13.20 12.68 13.14 14.19 14.71 15.64 12.70 13.26 13.40 13.47 12.77 14.55 14.13 14.15 12.51 14.76 14.56 14.66 13.73 10.78 11.59 12.83 13.94 12.99 14.71 14.61 12.14 12.34 15.18 12.61 13.55 13.73 12.92 14.91 13.48 12.71 13.66
SSSERAHQVLRI 13.85 12.85 12.18 13.76 13.38 14.17 12.56 12.27 14.11 14.05 13.44 12.86 14.11 13.74 13.56 13.10 13.67 13.57 13.24 15.33 9.67 15.66 12.80 11.49 13.54 13.10 15.13 15.35 13.99 14.18 11.67 13.38 12.98 13.34 13.02 11.82 12.53 12.05 14.64 13.51 11.87 13.74 16.46 12.86 13.48 11.54 14.11 13.76 14.44 13.82 15.05 16.24 16.17 11.88 13.69 13.07 13.96 12.31 14.16 12.68 11.13 14.37 15.46 13.91 15.45 15.71 16.34 14.59 13.09 10.95 15.06 15.16 14.48 15.76 14.49 14.21 15.60 13.87 12.93 13.86 13.70 14.06 12.59 14.01 13.42 14.25 13.56
PVAEELSHHENL 12.94 14.72 15.08 14.21 13.20 13.92 14.16 15.63 13.53 13.26 14.91 14.25 14.02 13.68 14.63 15.13 14.76 14.48 13.99 14.21 14.29 14.05 12.95 13.56 13.84 13.11 14.18 13.31 14.86 14.76 14.89 14.82 14.86 15.99 13.41 15.20 14.51 14.18 13.72 13.23 14.56 14.18 11.89 13.90 14.54 14.10 13.19 13.98 15.27 14.89 15.10 13.59 13.62 14.43 14.82 13.57 14.89 14.87 15.29 15.66 15.04 13.76 14.43 14.62 14.66 13.87 15.56 14.58 13.57 14.40 14.13 14.86 13.71 13.67 14.16 14.12 14.26 15.02 14.72 14.92 15.40 14.60 14.85 15.02 14.95 14.45 14.72
AVALTKGGEARGEL 13.60 13.61 13.47 14.57 10.57 15.44 13.44 14.30 10.00 15.14 11.60 13.96 12.79 12.93 14.72 12.01 15.46 14.45 15.69 14.24 13.59 13.11 13.74 13.24 12.30 13.75 11.77 15.40 14.75 14.16 13.44 12.12 13.55 13.13 12.70 14.19 13.23 13.96 14.85 14.13 14.51 13.71 12.33 13.93 15.31 13.80 13.87 12.85 15.25 15.31 13.41 13.07 15.05 12.14 14.51 14.92 14.13 15.01 15.61 14.82 13.75 12.90 11.26 11.88 13.24 14.75 15.70 13.43 14.17 12.19 13.15 15.32 14.26 14.33 11.52 14.19 15.68 14.13 15.52 14.07 13.00 14.56 14.56 16.23 15.98 14.04 14.20
PENEKGPFPKNL 13.17 12.61 16.14 13.80 14.55 14.68 12.32 13.09 14.12 14.35 13.94 13.06 13.37 13.49 13.37 13.52 14.99 14.62 12.65 13.63 14.76 15.16 14.24 10.98 13.90 12.81 15.95 16.20 13.73 12.21 15.70 15.09 13.16 13.53 13.42 15.27 13.57 14.93 13.63 12.94 12.33 14.18 16.24 13.37 14.33 13.70 13.54 14.20 14.55 15.16 14.58 13.80 12.79 13.51 15.20 13.54 14.00 12.94 16.93 14.37 14.46 15.60 15.86 13.70 13.12 15.17 12.78 12.49 13.01 13.49 15.05 16.03 13.53 13.67 14.36 16.33 15.25 15.00 14.21 14.55 14.51 15.19 12.73 13.70 11.89 14.20 14.12
TPLGPKWPEPVF 15.74 14.07 14.12 14.84 16.83 15.46 15.98 16.38 15.50 14.11 12.75 15.99 16.59 15.37 16.10 16.15 15.59 16.52 15.13 13.59 16.92 16.24 13.18 17.67 17.12 14.91 16.74 14.88 15.95 15.50 12.67 17.48 15.52 14.72 15.63 16.40 14.27 14.77 12.57 17.25 13.06 15.02 14.00 16.78 14.60 16.76 12.55 14.26 16.60 17.54 17.18 13.73 14.13 17.53 15.21 14.32 16.68 16.94 15.50 18.81 13.98 17.14 14.08 14.50 13.91 16.35 15.41 16.15 17.33 17.63 16.49 13.05 15.31 17.83 18.20 14.37 16.02 17.33 13.69 12.80 15.08 16.29 17.87 14.83 14.25 16.51 16.84
VKVWPQQPSGEL 14.13 10.97 13.63 11.58 12.83 14.29 13.07 12.43 12.68 13.76 12.59 13.91 12.98 12.38 13.78 14.07 17.36 16.07 13.03 15.13 12.83 10.68 14.33 11.75 13.51 13.52 15.07 14.21 11.57 14.88 13.41 15.86 16.09 14.40 11.66 13.67 13.43 11.87 11.06 12.54 12.75 13.04 14.95 15.58 14.44 14.82 14.77 12.57 14.38 13.48 14.83 13.20 12.88 14.29 12.73 12.77 9.77 13.95 13.98 14.86 13.32 13.10 15.87 14.37 14.85 11.54 14.43 13.84 14.54 11.46 14.04 13.80 13.70 13.82 12.31 12.42 14.90 11.56 12.66 15.09 14.07 14.30 14.76 13.64 12.95 13.46 13.59
RAHGQESAIFNE 14.42 11.24 15.04 14.78 14.33 14.56 9.69 11.87 14.09 11.22 13.13 13.64 14.16 13.58 12.46 13.68 15.88 14.47 12.58 12.46 13.06 14.83 12.22 14.45 14.40 14.18 13.55 10.26 13.70 15.02 13.19 14.42 12.94 13.71 10.87 13.08 14.99 13.69 13.56 14.35 13.24 13.81 10.77 14.48 13.98 15.53 13.75 12.95 14.58 12.67 14.21 15.11 13.15 14.94 14.15 14.37 15.28 14.29 15.11 14.72 12.63 15.03 16.18 14.80 14.21 12.98 16.38 14.78 14.77 12.69 13.24 13.60 13.34 15.08 12.86 11.71 14.64 12.97 13.71 14.78 14.92 15.26 15.18 13.61 13.25 13.45 15.12
FQVRANSAGATRA 13.97 13.52 14.47 14.94 14.51 15.30 15.43 14.53 15.18 14.44 15.49 14.93 14.56 14.45 14.58 15.26 16.91 14.37 13.04 13.19 14.99 14.23 12.38 14.19 15.54 13.60 16.15 15.23 14.58 13.96 15.42 16.18 15.55 15.88 13.04 14.14 14.00 15.03 14.86 12.77 13.67 15.04 15.05 14.37 13.93 14.46 17.72 15.43 15.53 16.38 15.28 13.45 15.37 15.75 15.70 15.26 15.10 14.01 14.90 15.99 14.51 15.04 14.25 13.15 14.78 15.12 15.05 16.03 15.38 17.57 15.51 16.85 15.79 15.27 14.15 13.97 14.70 14.56 15.37 15.20 13.85 14.48 14.88 15.70 14.68 13.82 15.17
LVIKGARDSHAGL 14.75 14.93 14.80 15.58 14.54 14.68 14.52 14.80 14.67 14.88 14.41 14.26 15.39 14.71 15.69 13.10 16.37 15.18 13.72 15.18 15.23 16.22 13.97 14.89 15.80 15.79 13.96 16.04 14.23 14.96 14.50 15.88 14.36 14.74 15.05 14.15 14.15 15.75 14.50 16.54 14.08 15.50 15.12 14.26 14.86 16.17 16.85 16.32 16.38 15.99 16.81 16.50 15.31 16.83 15.70 15.79 15.82 15.48 14.96 14.63 14.32 16.37 15.35 14.64 14.46 16.21 16.24 16.82 15.53 15.05 14.48 16.77 16.03 16.76 16.17 14.58 15.32 15.18 14.77 15.72 15.16 16.19 15.22 16.31 13.12 14.87 16.10
ANKADRDQYEL 15.82 13.09 13.10 13.31 14.37 14.02 13.53 13.46 13.99 13.84 13.68 12.79 13.36 13.07 13.49 14.28 14.43 13.59 15.14 11.83 13.91 14.79 15.26 13.02 13.13 13.53 14.71 13.84 13.36 11.52 14.05 11.93 13.08 10.67 13.46 12.88 13.15 13.17 14.11 13.69 14.15 12.97 14.21 14.99 13.73 14.00 13.12 14.12 14.95 14.05 13.39 13.96 13.82 10.44 13.19 13.78 14.61 13.44 13.11 13.34 12.93 13.63 15.94 13.94 15.29 14.85 15.08 14.46 13.70 8.55 14.39 14.10 13.94 14.26 12.62 14.32 14.12 13.05 14.52 14.59 14.62 14.44 15.09 13.55 14.82 14.10 14.88
YSRTQTPRAEL 14.38 15.26 12.60 15.38 15.20 15.69 14.48 14.47 15.14 14.65 13.42 15.69 15.22 14.55 14.97 13.85 14.12 13.80 15.53 15.71 14.82 12.64 15.72 15.73 15.18 14.53 17.14 16.16 12.71 13.43 14.82 15.75 12.94 15.86 14.22 14.83 13.27 14.87 13.36 13.41 13.45 13.44 15.35 13.07 13.52 14.48 13.38 16.33 13.41 15.02 15.74 15.06 14.48 14.18 15.16 13.05 14.84 14.73 15.20 15.55 14.70 14.57 14.22 13.80 14.87 14.73 14.32 14.94 15.69 14.64 15.37 16.93 14.70 16.64 14.97 12.90 14.67 14.56 14.17 13.69 13.73 14.83 14.33 13.07 16.30 13.51 13.40
RAPEPALEPESL 13.35 13.64 12.89 12.83 11.52 12.49 13.01 13.08 12.57 13.51 13.49 13.02 11.86 13.21 12.60 11.70 11.20 11.67 13.97 11.93 13.46 10.79 12.00 12.19 11.55 13.78 10.48 13.80 12.95 12.52 13.27 12.92 12.45 13.20 11.75 12.38 13.00 12.38 13.49 12.99 13.08 12.61 13.67 13.51 13.54 12.80 14.05 12.58 12.42 13.50 11.27 13.31 13.72 12.92 13.00 14.11 12.50 14.96 13.19 12.43 14.14 13.97 15.05 14.13 18.28 11.79 12.43 14.83 14.19 14.17 13.56 12.92 11.38 11.58 13.66 17.28 12.70 13.57 14.63 13.05 13.68 12.83 14.40 13.04 11.42 13.87 14.09
VVENGESSQGRF 12.90 13.61 16.14 15.13 13.87 13.10 13.57 15.51 13.36 14.23 14.90 15.30 12.45 15.20 13.69 14.21 14.49 13.68 13.59 13.81 13.79 15.85 15.27 13.62 14.09 14.05 14.64 14.24 15.41 15.76 13.48 15.58 14.13 14.52 14.78 15.62 15.99 11.04 7.78 9.27 14.34 14.62 12.92 14.51 12.74 13.61 13.69 14.00 12.66 13.32 14.29 14.02 13.95 14.32 13.76 12.46 13.31 13.56 13.22 15.87 14.81 11.08 9.86 19.32 16.08 12.71 14.67 14.39 12.88 16.41 14.20 15.11 14.69 14.99 14.79 15.18 14.12 12.81 15.52 15.65 14.04 14.62 17.63 12.68 14.43 15.24 15.38
AASLAGPHSIVGRA 13.45 11.86 13.72 11.67 11.60 12.94 13.83 13.81 12.02 12.93 13.52 13.34 12.99 11.66 14.13 14.81 13.77 14.58 13.48 13.65 14.41 13.47 11.82 13.98 14.47 14.49 11.73 15.62 12.84 14.45 11.25 13.22 14.13 13.10 12.87 15.23 15.32 13.71 12.19 12.50 14.51 13.64 11.65 15.04 14.79 15.01 14.09 15.67 15.50 15.86 16.06 14.71 15.23 14.56 13.95 13.83 15.28 15.65 12.59 15.71 14.26 13.59 12.99 14.14 13.48 12.97 13.43 15.29 13.69 13.40 14.18 14.70 15.82 15.51 16.09 11.17 14.80 13.93 13.98 13.82 15.24 15.34 14.79 15.29 14.86 13.13 15.00
YGRAPQLRETL 13.90 15.14 15.40 15.41 14.94 14.33 16.17 14.91 16.97 15.73 18.30 16.99 16.86 17.38 15.10 9.65 16.26 16.95 18.05 15.30 14.96 13.94 16.03 15.42 15.03 17.02 14.24 14.71 15.70 16.34 16.36 16.63 16.85 15.90 15.52 15.96 14.64 16.53 17.02 15.95 14.51 16.54 15.16 15.82 14.16 16.35 15.32 15.43 15.28 17.63 16.60 16.38 17.49 16.86 17.84 17.79 16.92 18.45 18.26 17.11 16.93 16.98 16.37 13.23 14.49 16.53 15.91 17.26 17.24 16.65 18.34 18.62 17.43 16.29 13.50 18.26 10.55 16.83 16.53 16.46 16.40 17.54 16.81 17.27 17.69 16.22 17.26
YVVHTNYDEY 14.19 14.22 12.91 14.86 15.64 9.07 13.80 14.45 13.92 13.42 14.27 13.57 12.75 13.12 13.51 13.32 12.98 11.05 11.81 14.56 14.42 14.77 9.40 13.43 14.32 12.68 13.82 12.51 13.90 13.36 14.71 13.71 14.40 14.53 13.51 12.42 13.94 13.53 13.56 12.48 13.11 13.55 12.62 13.46 12.70 13.75 17.67 15.19 13.51 12.68 13.60 14.83 13.72 13.81 12.02 13.70 12.72 13.01 14.00 13.04 14.04 13.12 14.18 11.78 14.18 13.71 13.81 10.24 12.52 17.12 15.09 14.58 12.46 13.94 13.98 12.53 11.84 14.55 15.11 13.46 14.35 11.11 13.25 13.61 12.92 13.04 13.19
TYVPKEFNAET 14.33 15.71 15.59 15.45 16.02 14.74 14.73 14.01 14.07 14.73 14.16 14.38 13.96 13.28 15.09 14.71 12.02 15.00 15.28 13.53 15.81 16.43 12.36 14.30 12.27 14.03 16.13 15.90 14.31 14.07 15.26 12.65 15.38 12.19 15.94 15.73 15.52 13.81 14.87 14.96 15.46 13.18 13.70 17.05 15.14 13.35 11.79 14.72 15.73 12.70 14.24 13.60 13.46 13.31 14.64 14.12 15.88 14.81 13.63 14.41 13.03 12.98 15.14 16.35 15.70 12.29 15.35 13.11 13.28 12.80 12.31 13.14 15.47 15.62 14.09 11.94 13.47 14.46 16.14 16.93 14.53 16.25 15.54 13.98 15.52 14.72 13.35
EETLTHTITKL 15.01 14.96 15.26 14.59 12.77 15.29 14.14 15.67 15.06 14.48 15.75 14.94 14.86 14.48 15.26 14.88 14.91 17.28 13.74 14.91 15.91 14.18 15.56 14.34 14.49 15.78 15.97 16.60 11.95 15.28 14.08 14.46 12.91 13.44 15.49 14.89 16.81 15.15 14.44 14.10 15.89 15.59 16.51 15.62 16.70 17.02 14.17 15.39 12.50 16.49 15.66 15.12 15.78 16.43 14.24 15.93 15.25 15.83 15.28 14.28 14.74 13.40 15.91 14.90 15.09 13.99 14.34 13.67 16.29 16.92 16.55 14.43 14.80 16.30 15.75 14.05 17.32 14.75 16.24 15.35 14.91 16.54 15.41 14.51 16.12 17.31 15.97
LSDPDKVTIGLL 13.57 15.36 13.76 14.73 14.57 14.73 15.03 15.96 14.73 14.63 14.43 14.22 15.03 14.02 13.39 14.85 17.33 14.88 15.95 15.22 12.49 13.29 15.17 15.11 12.96 14.15 14.91 14.97 13.99 16.41 15.31 14.19 15.20 13.57 13.96 14.94 11.38 15.05 15.68 15.86 15.27 14.41 14.47 11.50 15.45 14.43 17.98 15.43 13.47 14.60 14.30 14.38 14.15 13.96 14.80 16.06 13.88 14.33 14.67 14.63 15.94 15.12 12.73 16.20 14.75 15.61 11.97 12.30 16.14 16.24 14.63 13.56 14.63 12.57 13.33 15.12 14.71 14.74 14.75 12.44 14.47 12.91 16.32 11.88 16.14 15.56 15.19
ASWDVEKTAIF 12.76 12.87 12.71 12.63 9.26 12.85 13.54 13.51 12.64 13.02 12.86 12.94 12.71 12.93 12.52 11.59 13.00 13.94 13.71 12.21 11.30 11.67 13.32 12.70 12.60 12.68 12.46 14.07 14.26 13.22 13.99 12.46 13.44 13.56 13.55 13.62 11.76 13.61 14.32 12.74 13.92 13.30 9.67 10.39 14.23 13.42 12.74 13.65 12.21 13.11 13.02 14.67 15.06 13.24 12.96 12.73 12.72 13.92 16.44 11.96 13.50 12.77 14.27 12.87 12.99 14.01 13.53 13.36 12.21 11.19 11.07 13.59 12.46 13.40 12.21 12.39 13.85 12.57 13.27 12.73 13.49 13.48 13.25 11.44 14.63 13.71 13.53
LRVAPEEHPVL 12.68 13.92 15.23 11.82 14.67 15.69 11.43 14.26 12.00 17.05 12.45 13.25 13.87 12.44 15.16 13.30 15.66 14.78 14.25 12.58 13.81 14.09 11.82 11.38 10.74 15.39 12.91 12.38 14.36 15.56 10.37 13.54 12.88 12.60 12.97 14.32 15.02 14.66 13.21 13.78 15.29 13.71 14.69 14.42 14.85 13.51 15.50 11.38 15.76 13.09 14.95 13.60 15.20 16.26 13.39 12.32 15.95 13.95 16.10 14.28 15.02 11.95 15.27 16.22 13.27 12.73 15.95 15.30 12.66 12.09 12.00 13.98 15.45 16.93 14.11 12.56 15.69 13.12 13.26 16.33 16.04 15.54 15.31 16.31 15.94 14.77 16.44
IVLWQPVTADL 12.12 13.90 15.47 13.31 12.37 13.31 12.51 13.07 14.60 12.85 13.11 12.54 12.39 13.63 12.61 11.15 13.92 13.03 14.18 12.76 12.70 13.38 13.07 13.45 12.78 13.70 12.93 11.79 13.03 13.21 13.33 11.90 13.31 10.93 13.43 13.81 13.76 13.29 14.23 13.73 13.46 12.97 12.59 12.85 13.80 12.99 12.70 11.53 13.03 13.21 13.62 13.59 14.13 12.56 13.34 12.65 13.43 14.01 13.46 13.23 14.07 13.96 14.51 13.11 11.83 14.19 12.81 14.16 13.67 12.61 15.25 15.15 12.90 13.35 10.63 17.77 13.96 12.97 12.93 12.83 11.35 13.48 13.30 13.37 13.75 13.56 14.67
DGVPGKDGPRGPT 15.92 16.35 17.60 16.62 17.16 16.73 16.18 16.95 17.13 15.92 15.58 16.03 16.04 15.80 16.37 16.80 16.64 16.50 17.06 17.29 16.28 15.46 17.50 15.79 15.48 16.21 17.58 15.84 17.55 17.39 16.86 16.21 15.51 17.11 16.64 16.74 15.58 16.45 16.95 15.88 16.72 16.81 17.18 17.05 16.46 16.27 17.64 16.43 17.45 17.35 16.29 16.24 17.15 16.43 17.55 17.29 17.60 16.64 16.70 17.23 15.47 17.55 17.07 15.97 18.47 16.17 16.86 15.94 16.12 16.76 16.69 16.10 17.57 16.15 16.26 14.72 17.19 17.79 17.00 16.89 17.39 17.55 17.76 16.93 17.02 16.70 16.73
GRLASPGFPGEY 13.43 12.62 10.33 14.49 14.36 13.79 15.37 14.30 15.38 14.08 12.95 15.10 14.26 14.44 13.50 13.91 13.22 13.64 13.19 13.33 14.21 14.32 14.32 14.94 14.49 12.37 15.19 12.40 14.09 13.70 13.63 15.71 14.19 13.36 12.90 15.05 13.92 14.07 12.34 13.90 13.73 13.71 13.73 14.99 12.22 14.28 11.71 14.64 12.41 16.50 14.65 12.19 12.77 14.03 14.59 12.21 13.58 14.57 14.45 16.82 10.91 13.95 15.23 13.54 14.21 15.01 14.40 14.28 14.38 15.64 14.87 13.00 13.74 13.84 15.86 13.94 12.94 13.55 13.42 13.20 13.87 11.23 15.66 12.57 13.05 14.29 14.20
FKSLPGQNEDL 14.22 15.39 13.20 13.44 14.50 13.27 12.84 13.69 15.00 13.70 13.78 12.87 13.33 12.75 13.47 14.20 12.44 13.81 13.14 13.31 15.05 15.91 12.99 12.92 14.18 13.43 15.23 11.78 14.30 13.50 12.87 13.10 13.68 11.83 14.99 13.42 11.85 12.04 14.24 12.74 12.59 13.94 14.72 13.95 13.84 12.89 17.13 14.26 15.27 13.94 13.51 13.29 14.25 13.17 14.29 14.10 15.68 13.39 12.59 11.66 13.51 15.01 11.66 16.33 14.78 14.45 15.57 14.07 13.78 15.83 14.24 14.17 13.00 14.45 15.69 17.74 14.81 13.87 15.17 14.03 13.55 13.88 15.24 13.70 13.53 14.46 14.00
VIKGARDSHAGL 16.05 17.45 17.16 17.16 15.69 17.12 15.70 17.35 16.03 15.73 16.25 15.69 15.62 16.16 18.01 15.38 16.24 16.66 17.00 15.76 17.01 16.99 16.25 18.04 16.27 16.50 13.93 18.79 16.56 16.66 15.39 16.28 16.04 17.20 17.74 15.96 16.44 16.52 16.12 16.94 15.97 17.78 17.07 17.11 16.92 17.72 17.95 19.42 18.30 17.52 18.42 16.23 15.30 18.69 18.59 15.52 16.49 15.88 16.80 15.94 17.71 15.93 15.03 17.75 16.71 14.57 18.38 17.90 17.58 17.27 17.85 17.27 17.25 17.25 17.43 16.38 16.94 16.57 17.70 14.31 18.63 18.40 17.43 18.45 16.59 16.56 17.93
DDEKNWGLSF 12.49 12.92 12.40 12.45 15.00 13.47 13.34 16.66 13.48 13.96 13.15 14.18 14.58 13.62 13.83 14.23 13.36 11.27 12.10 13.99 14.31 15.06 14.08 12.91 13.47 12.14 14.82 14.30 13.22 13.71 16.11 14.04 15.22 11.90 15.72 12.20 14.11 13.43 14.18 13.31 12.18 12.50 15.33 12.89 12.11 12.97 11.38 15.10 12.71 14.88 13.89 12.93 12.91 13.72 13.75 13.90 13.08 12.90 14.43 13.19 12.91 13.15 14.26 13.35 14.07 14.15 14.81 14.22 12.83 15.45 12.55 14.27 13.90 11.60 14.72 12.16 12.51 12.71 14.51 13.35 13.49 11.62 12.54 13.44 12.50 14.87 13.29
YEKTDTDGKF 14.01 14.36 14.31 15.51 15.83 15.50 15.26 13.54 15.18 14.79 14.80 15.51 15.37 15.52 14.45 13.72 12.46 11.82 13.86 13.71 13.87 17.89 16.22 15.88 14.21 13.19 16.72 12.91 13.46 12.74 15.01 15.48 11.90 15.82 14.90 14.17 15.89 15.35 13.88 14.41 12.53 14.86 14.68 15.33 13.73 15.43 17.26 15.34 14.77 15.66 11.74 15.46 13.42 14.09 14.12 13.97 12.87 13.83 14.26 14.38 14.78 14.40 13.76 14.01 14.65 13.99 13.52 14.83 14.83 15.68 14.67 15.22 14.31 13.22 15.15 13.66 14.32 14.99 15.45 14.43 15.01 14.43 14.11 14.91 12.87 13.40 15.93
ISWDGLDSGKL 12.93 11.99 12.36 11.59 10.36 12.24 12.98 12.80 13.02 12.81 12.15 12.20 13.52 12.45 9.87 13.08 12.79 13.49 11.41 11.55 13.12 10.54 11.89 12.67 12.41 12.55 13.01 10.17 12.04 12.62 12.29 12.12 11.48 12.83 13.47 13.48 10.60 12.16 12.59 12.22 12.55 11.59 13.43 13.52 9.64 12.64 10.93 12.52 12.73 12.42 10.79 13.19 12.55 14.28 12.31 12.55 12.24 12.76 13.45 11.23 12.81 11.54 12.14 12.42 13.03 12.15 11.99 12.38 12.32 13.60 13.37 11.73 11.33 13.09 11.88 11.49 13.43 12.86 12.38 12.41 11.20 11.01 11.84 12.36 12.85 12.11 11.96
WRQVEGM(+15.99)ED 12.49 13.43 16.59 14.28 15.76 13.21 13.13 13.80 13.80 12.39 14.13 13.42 9.72 14.16 12.87 13.01 13.00 8.04 13.28 16.11 15.10 15.06 11.59 13.01 12.85 8.52 11.98 15.74 14.73 14.02 14.01 14.15 13.78 13.14 14.81 13.84 15.78 13.19 13.29 13.82 12.47 11.54 13.01 14.69 13.46 10.69 13.64 13.39 15.75 13.76 13.39 13.89 13.52 11.82 12.49 13.39 12.87 13.54 12.47 13.85 14.19 14.39 10.70 13.08 14.54 14.95 15.73 13.67 13.55 15.21 14.69 13.08 12.25 14.63 12.02 17.17 12.81 13.77 13.71 15.05 14.24 11.30 13.70 14.20 13.27 12.62 10.91
KTALQPMVSAL 12.87 12.07 13.54 11.45 10.93 11.64 13.30 12.56 11.32 12.90 12.90 12.97 13.18 12.03 12.05 12.84 12.93 12.78 10.49 14.02 12.01 13.05 13.91 11.61 12.68 12.08 10.34 13.43 13.35 14.88 11.80 11.78 12.83 12.59 12.26 14.54 12.44 10.05 12.40 13.58 13.17 13.36 11.68 12.04 13.01 13.36 11.06 13.33 12.10 13.71 9.81 14.60 13.53 13.83 13.33 13.48 12.11 12.63 13.31 12.42 13.71 10.95 13.72 14.53 11.53 12.99 10.65 13.48 13.22 13.81 10.98 11.42 10.67 12.35 13.76 13.63 12.95 13.36 13.67 12.12 13.73 12.95 10.76 13.56 13.57 14.34 12.04
WRQVEGMED 14.25 13.79 12.37 13.16 15.75 13.92 13.83 11.42 13.41 14.79 14.87 14.53 12.99 14.47 14.88 15.37 12.98 14.95 13.29 15.85 16.79 14.49 12.71 15.32 14.39 13.18 11.01 14.75 8.65 13.72 15.55 15.70 15.86 14.87 15.23 13.46 15.87 14.39 13.67 13.57 14.59 13.33 13.62 14.79 13.76 12.98 15.21 14.44 15.08 13.62 15.17 14.04 13.85 15.92 9.59 13.35 14.17 14.15 13.28 14.03 16.27 11.13 15.20 13.63 13.34 14.11 15.22 13.78 13.70 10.17 15.54 14.43 14.55 14.02 13.37 15.51 13.47 14.42 13.77 16.59 14.62 13.01 12.98 13.32 12.69 13.42 14.19
YVVHTNYDE 12.10 14.49 14.09 15.27 14.57 13.71 13.86 14.09 14.12 14.22 16.36 14.31 14.09 13.71 14.68 14.53 13.50 12.50 14.60 14.00 15.49 14.56 13.40 11.47 14.16 15.18 13.60 11.19 14.42 14.34 14.39 13.88 14.66 13.95 14.55 13.44 15.61 14.81 14.67 13.93 12.54 13.95 13.78 14.63 14.14 12.74 13.31 15.06 13.56 13.96 14.39 13.27 14.58 13.50 14.16 15.26 13.96 15.25 11.27 15.57 15.45 14.25 14.31 12.72 14.92 14.46 13.83 14.62 14.80 15.10 15.55 14.44 13.42 12.43 13.72 14.02 12.48 16.00 14.88 14.07 14.41 13.95 14.05 13.74 13.64 13.80 14.25
PGKDGPRGPTGP 16.58 16.46 17.47 17.88 17.71 19.40 16.98 16.88 17.91 17.00 16.46 17.07 15.92 17.65 15.77 16.25 13.75 16.83 14.94 15.28 16.18 16.16 16.71 16.33 17.36 18.54 16.60 16.71 19.45 16.48 15.46 15.61 15.64 15.96 15.62 19.07 15.53 15.91 17.29 17.09 16.46 15.04 15.24 16.66 17.65 16.60 14.84 17.37 17.32 16.88 17.29 16.46 16.01 16.92 16.40 17.41 16.61 18.03 14.15 17.42 18.90 15.00 15.80 15.20 16.49 15.85 15.38 13.05 15.99 17.38 17.21 16.45 16.68 17.42 16.70 15.62 15.86 17.26 14.73 18.84 16.40 16.89 15.68 16.60 16.06 16.45 17.75
VQVFAPANALP 10.22 13.35 13.69 12.97 9.75 12.53 13.63 12.00 13.06 12.91 13.82 12.33 14.24 12.95 14.25 13.72 12.06 13.08 12.59 13.10 11.56 14.47 12.56 13.05 12.71 13.89 11.60 12.24 13.91 13.26 13.63 12.30 12.14 13.04 13.65 12.75 14.38 13.13 13.86 11.96 13.96 12.04 13.57 13.28 13.43 13.58 10.75 13.20 14.00 11.55 12.98 13.42 12.79 14.21 13.70 12.46 12.25 13.30 13.36 9.28 12.76 14.04 12.69 13.09 13.65 12.63 11.99 12.91 12.54 11.21 12.27 13.10 11.52 12.54 12.76 13.65 12.78 13.08 13.87 13.07 14.52 12.56 12.65 13.97 12.96 13.18 12.15
HQDWLNGKE 12.30 12.77 14.27 13.14 12.65 15.08 13.14 11.23 12.89 13.87 15.57 12.65 13.11 12.97 13.99 11.59 13.87 14.23 12.82 11.84 13.33 13.07 12.96 12.05 13.36 14.15 12.91 13.05 14.77 13.47 13.18 13.71 8.52 12.65 12.76 15.53 12.97 12.58 14.67 13.43 14.79 13.17 15.66 13.99 14.27 13.70 13.58 14.90 13.51 14.60 12.99 11.03 13.99 11.60 14.22 12.87 13.78 14.26 13.12 15.03 13.37 14.00 14.47 10.84 14.97 13.07 13.66 13.16 12.65 13.94 13.00 12.89 12.50 15.57 11.65 12.52 14.52 13.86 13.11 11.70 13.82 14.62 13.00 15.73 12.71 11.57 14.69
ASWDVEKTAI 13.07 14.46 14.08 13.27 12.39 12.88 13.27 13.82 13.30 15.27 12.73 13.46 12.42 12.41 12.78 13.52 12.86 12.25 12.59 11.04 12.70 14.47 11.26 11.52 12.24 13.38 14.11 14.86 14.21 12.80 14.38 13.11 13.51 13.77 12.06 12.39 13.91 12.40 14.27 13.00 13.35 14.04 13.45 12.68 14.43 12.08 12.81 13.24 11.40 14.20 12.60 12.16 14.34 12.77 12.70 14.83 13.96 13.40 13.55 12.15 13.17 11.74 12.99 14.37 17.35 14.62 14.88 12.20 11.57 15.12 11.90 12.72 12.93 12.55 13.81 17.13 13.23 12.13 15.71 13.33 14.64 12.44 14.03 12.81 13.45 13.99 12.74
YKAIPVAQDL 12.36 13.52 13.41 14.17 13.89 14.00 14.83 14.11 12.60 12.64 13.70 12.45 14.78 12.41 13.43 13.60 8.11 14.83 11.73 14.33 15.11 15.92 13.98 12.73 13.34 11.63 14.81 11.33 13.73 10.93 12.95 13.53 12.72 11.02 12.56 12.40 12.75 13.25 13.50 12.08 13.32 13.01 12.34 13.23 14.84 11.97 16.45 16.08 13.31 13.83 13.81 11.88 13.53 12.41 13.51 14.36 13.31 11.45 13.26 11.13 12.60 15.68 12.07 13.54 13.51 11.28 15.11 13.62 13.95 15.88 10.47 13.91 13.23 13.19 15.05 11.27 14.74 13.11 15.32 11.99 13.52 13.39 11.34 10.14 14.27 15.72 13.53
RAHGQESAIF 15.35 15.51 9.29 15.17 14.98 16.28 15.52 15.79 15.61 13.94 14.69 15.95 16.01 16.91 16.18 15.89 16.67 16.32 16.74 15.62 16.40 15.93 14.89 16.93 15.72 15.45 17.00 11.69 15.78 16.27 15.19 15.98 15.65 16.02 15.23 16.27 15.28 15.97 15.30 16.08 15.12 15.50 16.23 15.51 15.21 16.81 14.48 17.12 17.89 16.08 17.11 15.98 16.50 16.61 16.62 16.25 16.69 16.76 16.86 16.69 17.15 15.09 18.66 18.07 14.62 14.79 14.91 16.00 16.58 15.26 15.66 15.68 15.47 15.07 16.16 14.90 16.47 15.62 16.82 16.71 16.98 16.12 15.28 16.66 15.12 15.76 16.68
FRFAGNYDL 13.04 12.23 13.09 13.70 10.58 12.76 11.26 12.82 12.37 12.82 12.52 9.87 9.77 13.30 12.91 13.39 12.99 14.33 11.19 12.01 10.45 12.70 14.31 13.27 12.20 13.95 12.34 14.34 13.62 14.38 12.17 12.15 12.84 12.01 11.83 13.43 12.33 10.46 13.32 13.50 12.26 12.56 10.80 11.45 14.20 13.91 14.23 12.60 9.28 14.30 13.44 14.53 14.52 14.25 12.00 10.01 13.02 13.54 12.23 12.28 12.59 12.59 13.66 11.70 11.68 10.93 14.56 12.65 13.00 10.66 15.03 13.09 12.04 11.38 13.68 14.19 13.18 12.73 13.42 11.42 12.75 12.37 12.34 11.04 13.84 14.88 13.04
FSSPHGKDLL 15.14 15.02 15.80 13.95 16.08 12.29 11.75 13.72 13.84 14.18 13.76 13.48 13.00 14.58 16.95 15.04 16.92 17.66 17.34 13.91 17.33 13.14 11.75 10.64 13.25 14.89 15.15 16.20 13.91 13.98 14.92 13.79 15.13 11.56 16.67 15.91 14.75 14.53 15.11 15.28 16.48 13.73 14.72 15.94 15.53 13.69 14.54 14.18 16.69 13.45 15.22 14.78 14.67 14.70 16.02 13.76 17.38 16.20 16.36 15.47 14.45 16.84 16.37 18.96 16.16 15.83 14.79 15.68 15.13 14.16 10.53 14.62 15.73 16.54 15.51 13.59 15.02 13.93 16.19 16.87 13.52 16.05 16.70 14.35 17.43 15.81 15.89
PILRHGIQY 16.00 13.27 13.21 13.03 15.31 12.05 13.27 12.18 13.47 10.78 11.60 14.08 13.78 13.37 9.24 15.30 14.21 14.29 12.50 14.61 14.11 15.07 13.34 14.33 14.40 11.63 14.72 15.67 13.57 13.75 11.43 13.54 13.00 13.51 13.95 13.29 13.37 13.40 10.01 12.27 11.64 12.68 16.11 13.64 11.18 16.86 13.59 15.79 13.93 16.19 13.56 15.91 14.44 15.86 14.21 13.73 13.47 13.43 11.05 14.70 14.67 12.51 14.85 14.99 14.02 15.95 16.22 14.98 10.68 15.82 15.78 13.84 15.10 17.06 15.13 15.06 15.63 14.55 13.86 14.08 14.16 11.94 13.33 12.78 13.14 14.74 11.78
AVRLVFQDF 12.63 12.67 12.11 13.64 10.96 13.02 13.40 13.33 12.07 12.90 12.67 13.15 12.33 12.70 11.72 12.91 12.33 13.25 13.74 11.44 13.45 13.37 12.85 13.87 12.77 12.88 11.29 13.67 12.27 12.30 12.81 11.91 11.57 13.17 12.47 13.98 12.20 12.42 12.89 13.04 12.99 12.78 12.63 13.43 14.18 13.55 12.05 14.18 12.80 13.26 14.27 13.75 14.05 12.34 13.56 13.37 12.90 13.17 13.39 13.83 14.18 13.46 12.42 13.06 12.89 12.05 11.34 13.07 13.85 13.26 13.33 13.26 13.59 13.76 13.21 11.92 13.85 12.41 13.49 13.75 12.43 12.94 12.70 11.45 13.53 12.14 13.45
GRLASPGFPGE 12.74 12.88 15.16 13.41 14.72 13.07 12.48 13.09 14.67 13.62 13.21 12.21 13.51 12.07 12.86 13.74 13.53 13.39 12.22 13.36 12.41 15.77 14.77 13.49 14.68 11.23 15.40 15.35 12.10 13.37 12.44 14.56 13.15 12.91 14.79 15.04 15.04 12.21 14.18 15.02 13.81 13.52 13.51 14.06 13.37 14.20 14.37 13.66 15.63 15.03 13.40 13.96 16.96 13.77 14.54 14.39 13.73 13.88 12.85 15.59 14.33 14.60 14.84 13.42 12.14 16.07 13.24 14.22 14.55 16.59 12.10 12.27 13.05 14.34 16.75 17.60 14.32 12.47 14.36 14.96 12.94 14.00 15.26 14.61 13.34 13.57 13.38
GPKWPEPVF 13.66 13.49 13.78 14.55 10.52 14.44 13.40 13.97 15.47 13.39 15.32 13.43 14.13 13.63 13.64 12.07 13.82 14.40 13.58 14.40 14.44 13.84 14.12 13.15 13.63 14.11 13.19 12.75 13.86 14.28 15.22 13.26 14.21 12.64 12.02 14.99 15.37 15.20 14.67 15.31 13.12 11.90 11.83 14.84 13.93 13.91 14.52 16.24 13.30 16.17 13.98 16.02 15.14 13.69 7.05 13.54 13.42 15.00 17.23 17.08 13.32 13.91 14.37 13.67 14.41 13.87 13.37 13.61 13.38 15.98 15.41 15.74 13.98 13.99 13.62 13.39 13.36 15.08 13.98 14.21 13.95 11.95 14.55 14.96 15.41 13.22 13.33
IVDKVKPQL 13.80 15.05 13.23 14.26 14.94 14.39 13.69 14.72 16.51 14.57 11.48 13.20 14.59 14.15 15.09 9.81 13.17 13.64 13.98 15.21 16.05 17.19 13.46 14.38 14.58 13.79 15.68 12.28 15.56 13.64 13.37 13.30 13.06 13.31 15.98 15.69 11.10 12.41 14.45 11.59 13.29 14.27 15.30 11.87 15.31 13.65 10.62 14.97 13.04 14.82 15.43 13.22 14.04 14.59 13.67 16.04 15.42 13.89 13.20 15.89 12.87 15.87 12.95 11.38 15.58 15.06 12.29 14.29 13.36 16.86 10.41 14.42 14.83 13.60 15.82 13.07 14.25 11.96 14.62 14.55 11.79 15.79 14.02 15.06 12.47 14.45 13.72
VVLPKHILD 12.35 10.89 16.43 13.51 12.14 13.02 12.05 12.56 15.19 12.41 14.55 9.09 12.86 11.42 13.10 13.17 13.28 13.23 10.16 13.91 12.12 12.51 14.16 13.03 13.14 12.98 10.05 14.51 13.08 12.40 12.29 12.25 12.34 13.09 13.33 13.82 13.30 12.94 14.75 12.82 12.43 12.80 11.52 13.50 13.38 13.97 13.29 13.59 11.82 13.08 14.07 13.26 13.92 12.37 14.64 13.19 12.65 12.49 9.09 13.33 12.42 14.07 13.50 12.99 14.25 14.03 14.19 13.29 12.65 12.83 11.72 14.51 12.82 12.14 12.34 13.40 13.30 13.64 11.79 14.18 11.91 10.20 12.49 10.85 12.66 13.17 13.07
NVAKGIRSF 13.71 13.32 13.62 13.96 14.01 13.28 13.32 13.02 14.03 16.27 13.90 12.51 12.68 14.01 16.03 13.31 12.34 13.68 13.44 12.87 12.71 13.11 13.01 13.58 14.48 13.69 13.65 15.20 15.22 12.85 14.84 13.49 13.32 12.82 15.45 13.45 14.63 14.57 15.22 14.10 14.18 12.02 13.67 14.55 13.56 14.41 14.56 15.23 14.61 15.13 15.02 14.31 15.42 13.93 13.88 13.55 14.34 13.09 16.38 13.74 14.47 14.94 14.97 15.36 15.22 15.82 15.58 14.15 12.68 13.95 15.84 15.32 15.68 14.81 13.55 14.66 14.61 14.52 15.10 14.30 15.11 13.38 14.40 13.17 15.54 14.76 14.74
VLNLGPITR 14.43 16.57 14.60 15.46 15.10 15.29 15.79 14.42 15.41 14.98 15.69 15.76 15.12 14.47 15.86 15.03 15.41 15.86 15.15 15.15 15.37 15.15 13.84 12.39 14.71 15.17 16.44 15.21 15.34 15.23 15.97 14.02 14.61 13.53 13.46 14.45 14.83 16.24 15.60 15.63 15.76 14.44 12.84 14.06 16.05 15.16 15.69 16.93 13.42 16.03 15.73 14.40 16.26 13.50 15.90 16.53 15.98 16.06 13.41 16.78 15.49 16.00 16.26 15.48 15.71 14.59 15.06 15.38 14.98 15.57 16.10 15.93 17.02 15.29 13.89 13.47 15.55 16.09 15.46 15.78 16.12 16.24 15.63 14.04 16.20 16.99 14.52
PGKDGPRGPT 15.54 16.20 16.54 16.88 16.05 17.69 16.81 16.68 16.68 16.69 16.10 16.35 15.70 15.68 16.24 17.22 15.61 15.37 16.32 16.74 15.70 14.92 16.40 15.54 15.70 16.25 17.22 16.04 16.79 16.77 16.13 15.94 15.55 16.89 15.70 16.55 14.78 16.11 16.73 16.28 16.67 16.34 16.45 16.73 17.13 16.88 18.87 16.29 16.75 16.65 16.67 15.50 17.62 15.76 17.08 16.75 16.85 16.14 16.23 17.18 15.24 17.24 16.93 15.31 16.83 16.36 16.15 15.84 16.23 16.85 16.28 16.46 17.20 16.38 16.29 15.13 16.54 17.31 16.55 17.09 17.36 17.49 16.79 16.92 16.84 16.12 17.49
KELKFVTL 13.99 13.36 14.00 13.72 13.86 13.31 14.11 12.02 11.65 11.57 9.47 12.17 13.06 12.50 15.10 14.65 13.57 13.69 13.06 12.47 14.28 14.34 11.67 13.16 14.07 10.69 10.38 14.73 14.07 13.91 14.13 13.71 13.20 12.32 12.16 14.42 13.14 12.82 12.55 13.16 13.53 13.22 14.35 13.66 13.68 14.97 12.62 13.81 15.46 13.83 15.45 14.08 13.81 13.81 13.14 11.90 12.38 14.64 12.39 15.27 13.11 14.76 14.38 11.45 13.78 14.65 12.65 14.03 12.93 13.23 14.79 11.05 12.86 13.35 12.42 12.57 13.25 14.29 14.49 13.93 14.24 14.69 12.95 15.31 12.48 12.77 13.81
SKWSGPLSL 12.99 12.54 12.48 11.76 9.17 11.94 10.86 11.88 11.07 12.72 11.01 11.92 13.35 12.07 12.38 11.98 11.20 12.60 11.76 11.50 12.85 12.30 11.83 13.06 12.20 13.00 11.84 12.50 10.70 12.55 12.91 11.82 9.96 12.89 12.97 12.23 13.57 10.58 13.41 12.06 12.43 11.80 12.52 13.57 12.70 13.24 10.76 12.10 12.23 12.66 12.66 11.17 12.51 12.67 12.24 11.75 10.63 12.99 13.35 10.85 12.92 12.71 10.35 12.82 11.73 13.09 12.98 13.04 13.05 12.04 13.02 12.78 11.76 13.59 11.73 16.04 13.43 11.99 13.07 8.71 13.50 11.47 11.63 13.57 10.59 12.40 11.84
YKWKETL 14.18 13.60 13.72 13.29 16.45 14.85 14.47 14.40 15.03 15.20 15.00 14.12 14.17 12.46 13.69 13.74 13.97 12.17 11.82 13.63 14.99 11.04 14.43 15.09 14.08 15.33 15.78 16.22 13.65 12.83 12.60 14.98 12.91 14.63 14.21 13.12 14.87 14.16 15.41 15.23 13.22 14.44 16.32 14.18 14.12 15.74 18.04 13.56 15.45 15.88 14.27 15.10 15.36 15.86 14.43 14.75 14.21 13.91 13.44 16.04 15.56 14.19 15.20 12.20 13.56 15.82 16.00 14.91 14.84 16.28 15.07 15.21 13.85 15.48 13.61 15.69 15.12 14.66 15.01 14.35 14.53 14.99 14.85 14.85 15.46 13.65 14.73
PRYPVGKF 15.40 15.95 13.57 15.77 15.19 15.78 16.56 14.48 15.99 14.21 14.53 15.59 16.31 15.37 15.17 16.12 13.82 15.31 14.34 13.75 14.64 15.97 15.12 14.24 14.93 15.12 17.22 16.10 17.52 16.09 14.29 15.39 14.51 13.23 15.75 15.37 14.85 15.45 15.74 14.46 15.72 12.90 14.32 14.58 15.77 16.37 16.27 16.59 16.08 16.61 17.17 16.42 16.82 16.50 16.33 14.65 16.02 15.73 13.75 15.96 15.26 16.57 15.61 14.29 15.22 15.39 17.70 14.39 13.51 15.03 14.30 15.51 15.32 15.85 16.12 12.77 14.54 16.09 16.21 15.56 18.13 15.87 15.87 17.35 17.36 16.97 16.05
RPPGFSPF 14.19 13.68 13.73 14.29 13.68 14.71 14.32 10.37 13.16 14.11 13.30 14.53 13.94 14.90 14.22 14.00 13.65 12.83 13.73 13.19 15.48 13.54 12.05 12.90 14.08 13.15 14.57 14.54 13.81 14.53 14.23 12.83 15.18 12.95 14.73 12.63 14.24 13.30 13.96 13.87 13.61 13.18 11.92 13.89 14.87 14.44 15.32 14.04 13.09 12.24 15.78 13.13 13.92 15.33 13.92 14.36 13.83 14.74 13.19 14.43 15.23 14.11 13.91 8.89 13.78 14.69 15.85 13.81 14.83 10.83 14.63 15.18 14.20 15.40 12.97 13.25 14.32 14.89 14.05 14.23 15.26 12.62 14.56 14.68 13.56 14.03 14.16
LNLGPITR 15.86 16.56 15.31 15.14 15.55 15.99 15.17 16.06 14.91 15.40 15.19 15.71 16.47 14.90 16.36 16.05 14.24 17.94 15.89 16.14 15.93 17.25 16.37 14.40 15.04 16.29 15.55 15.20 16.40 17.09 14.56 15.06 15.09 14.07 15.92 15.63 17.44 15.58 16.58 14.58 16.75 16.38 15.43 16.20 17.28 16.56 15.84 18.37 16.65 16.47 16.46 14.37 16.42 16.68 17.16 15.33 16.24 16.21 15.65 16.58 16.36 16.85 16.28 16.33 16.28 15.52 14.54 15.89 16.76 15.74 15.75 15.88 16.29 16.59 14.75 13.05 17.22 15.68 17.18 15.16 17.86 16.87 16.01 15.60 16.13 17.61 16.42
FTVRMAL 12.62 13.06 12.57 14.64 14.15 12.83 13.15 12.51 12.49 13.34 12.40 13.08 12.47 13.48 14.80 14.46 12.59 12.82 11.56 14.71 12.58 13.54 14.84 13.42 13.30 13.04 14.38 13.92 14.56 16.07 12.28 12.55 14.80 12.29 15.31 13.03 14.72 12.59 13.13 14.78 14.72 14.25 12.24 13.74 14.34 14.13 13.07 14.49 13.85 15.47 13.35 14.46 14.23 13.29 13.75 13.49 13.66 14.55 14.28 14.36 15.17 13.02 13.99 13.15 14.31 13.77 14.64 13.27 13.55 12.69 15.12 12.83 13.90 13.31 14.48 12.61 14.56 14.13 15.03 13.23 13.77 13.59 12.57 14.13 13.63 15.32 13.68
MGPPGNPGP 15.68 17.31 15.91 18.23 15.02 17.79 17.01 16.52 17.30 11.15 16.67 16.21 16.60 17.45 16.20 16.68 15.48 15.06 18.41 12.18 16.38 16.09 16.12 16.14 14.49 16.34 16.59 15.73 16.40 17.80 15.69 15.56 14.87 15.88 14.96 17.01 14.67 11.96 15.59 17.60 17.60 15.60 14.91 15.32 17.25 15.26 18.27 16.66 17.12 17.54 17.61 15.75 16.83 17.70 16.92 16.64 16.70 17.54 16.34 16.61 16.24 17.93 17.30 16.82 15.82 17.30 15.71 14.25 16.26 16.65 15.80 16.61 17.61 18.10 17.15 17.03 17.50 16.70 16.76 16.52 18.90 16.72 15.38 19.01 15.80 12.99 19.10
HASLDKF 15.92 14.08 16.70 14.02 13.09 14.89 10.29 15.87 13.03 11.85 12.64 13.12 9.65 12.29 13.78 14.00 13.41 13.94 14.15 13.46 13.06 13.10 14.60 13.29 13.95 13.48 13.89 13.53 14.50 14.36 13.95 12.45 13.86 13.67 15.73 13.59 14.54 13.35 14.15 9.05 16.32 15.26 14.01 14.61 13.69 15.28 10.36 11.01 15.53 12.05 13.70 15.83 15.06 13.71 14.36 15.82 15.81 14.45 15.06 14.19 14.00 15.85 14.05 17.24 15.38 14.58 14.99 14.06 12.94 13.46 14.55 13.55 14.22 13.44 13.82 15.30 14.12 12.53 14.52 14.45 15.69 14.72 14.04 14.54 14.42 15.22 14.59
FESFGDL 12.42 8.90 10.95 10.48 9.63 11.55 12.49 12.64 10.22 11.47 8.49 12.33 9.31 10.09 11.53 12.48 9.83 11.27 12.02 13.29 12.88 9.63 9.67 11.50 12.54 13.16 8.12 11.52 10.95 11.62 12.81 10.53 10.56 13.51 10.20 9.78 13.68 12.46 13.09 10.20 11.17 11.42 11.02 13.78 13.00 13.28 10.41 11.31 12.18 12.95 12.39 10.65 12.53 13.29 9.98 10.82 11.61 8.32 15.68 11.62 9.62 10.33 12.88 13.29 13.67 11.40 10.38 12.77 11.25 10.06 11.01 12.90 9.58 10.76 10.87 11.62 13.03 13.85 10.87 13.22 10.61 12.65 14.99 14.35 11.39 8.94 10.09
PPPPPPPP 12.08 15.18 17.22 14.52 14.63 12.98 13.93 14.07 13.90 11.71 15.01 13.09 14.02 13.72 12.15 14.07 12.64 15.01 14.09 13.40 13.93 14.20 14.36 14.36 13.55 14.14 14.81 14.38 14.66 13.87 14.55 13.81 13.04 13.18 14.83 14.89 14.73 14.25 13.83 13.74 13.97 13.79 14.53 13.87 14.10 12.64 13.00 12.72 17.79 13.88 13.22 13.92 14.97 14.54 15.46 13.21 14.92 14.47 12.80 16.05 14.25 14.69 14.79 13.71 15.08 14.89 15.18 14.04 12.78 14.21 13.94 14.26 9.58 15.15 14.73 18.19 14.48 14.43 13.89 14.52 14.91 14.76 13.89 14.60 14.82 14.96 14.60
KLGHPDT 10.64 14.43 17.31 13.33 12.75 13.51 12.26 9.69 16.03 11.97 14.22 11.15 11.25 12.22 12.55 13.23 14.17 10.15 11.48 12.35 13.34 10.93 12.76 11.22 12.75 11.51 12.73 13.43 13.57 13.11 11.51 11.82 12.51 13.41 12.82 14.34 11.55 11.63 14.43 13.29 13.05 12.26 9.59 12.60 12.85 13.14 12.17 12.68 12.12 12.14 13.42 10.05 13.81 13.11 13.79 13.64 13.25 12.79 8.92 12.96 11.61 14.43 12.11 12.87 13.22 12.66 13.22 13.18 10.94 12.36 12.69 11.81 13.29 12.93 12.24 14.01 12.02 13.77 12.82 13.89 12.34 13.27 10.29 13.37 13.44 13.23 14.24
SDVFAAGT 15.07 16.65 15.60 12.93 14.56 17.07 16.19 13.44 17.77 15.26 15.16 11.22 14.18 16.69 16.34 16.23 17.77 13.96 15.96 15.63 15.26 15.18 12.63 14.94 12.13 15.35 12.97 16.02 15.42 16.95 11.40 17.44 15.32 14.78 15.03 14.92 15.83 14.83 15.32 18.10 16.95 18.01 14.70 12.38 16.45 10.42 17.81 16.27 16.19 14.79 16.86 14.51 12.01 15.85 14.14 13.13 16.52 15.71 15.22 15.02 13.76 15.18 14.77 13.94 16.10 16.01 16.36 17.21 14.99 13.18 15.72 13.40 16.72 17.58 16.07 15.37 13.32 17.72 17.74 11.29 15.60 13.94 17.04 12.06 15.84 14.60 15.44
APHGPGLI 13.10 13.23 12.69 13.18 13.99 13.84 10.02 10.60 14.29 14.39 13.42 12.07 12.89 13.00 14.37 12.94 13.73 14.12 9.49 14.44 12.92 14.66 13.00 12.09 13.83 12.20 14.32 14.71 13.44 13.11 12.84 14.78 12.80 14.21 12.71 13.70 14.05 12.04 13.41 12.80 12.68 13.25 14.81 12.77 14.11 13.92 14.08 13.37 11.40 9.01 13.26 14.41 13.44 13.12 13.76 11.81 14.42 13.85 13.50 15.00 13.31 13.61 14.93 13.16 13.09 12.88 12.29 13.16 13.78 12.61 12.38 12.95 12.46 13.05 13.72 11.80 14.80 13.34 13.37 13.09 13.26 12.90 14.13 10.06 12.43 12.65 12.93
PVVPVHL 13.35 13.09 13.42 13.16 11.62 12.45 12.99 11.42 13.27 13.79 12.21 14.31 12.34 14.82 14.54 13.46 10.95 13.10 12.96 12.89 12.00 10.11 14.80 14.55 12.37 13.36 13.15 11.02 14.97 13.04 14.54 12.13 11.72 12.32 12.88 12.63 13.47 14.90 14.01 13.39 14.70 13.74 12.82 11.27 13.11 12.05 10.81 13.17 12.22 12.93 12.99 13.48 12.43 12.68 14.06 15.40 11.59 13.39 12.73 13.95 11.11 14.99 15.14 13.04 11.69 15.17 13.06 15.67 12.04 12.73 12.34 11.65 15.16 11.88 13.06 15.06 12.98 13.20 15.09 13.58 11.98 14.48 11.18 14.06 13.25 13.57 12.34
KPALPAGT 12.82 10.54 11.91 13.63 10.80 12.62 13.12 12.55 11.45 12.80 12.93 12.80 10.61 10.76 12.82 11.54 10.00 12.82 13.53 13.79 13.59 12.19 14.66 12.58 13.78 12.43 11.92 12.21 13.27 11.86 13.55 11.04 12.25 13.33 13.14 13.46 13.64 12.79 10.97 11.13 13.04 11.46 13.20 13.50 13.78 14.90 11.78 13.78 12.67 11.54 14.63 14.01 13.93 13.21 12.18 14.56 12.26 11.51 13.50 13.46 12.66 14.04 13.65 12.33 11.52 11.50 11.65 13.27 13.92 12.87 13.02 13.35 11.50 12.20 13.77 13.56 12.83 10.19 13.77 13.79 14.13 12.23 13.62 13.93 12.87 13.12 12.18
APHGPGL 13.38 12.66 14.59 12.26 13.08 12.05 12.75 12.29 12.32 13.51 12.45 12.27 13.94 12.25 13.88 13.71 13.67 14.40 12.23 14.42 13.36 11.35 13.01 12.13 14.52 10.68 14.18 13.32 11.37 13.27 12.40 15.11 12.31 14.47 12.84 13.47 13.11 12.67 12.63 11.55 11.57 12.17 13.21 13.30 6.25 12.80 13.85 12.61 13.42 11.58 12.94 11.21 13.11 10.50 12.39 11.45 13.62 12.36 11.92 13.38 12.76 12.89 14.45 12.35 13.05 12.72 12.68 14.14 12.76 12.21 11.65 11.83 13.46 12.01 12.78 17.46 13.71 13.30 13.34 13.63 12.35 11.66 13.39 11.96 12.52 10.65 12.14
AGPSSPT 11.08 12.29 12.85 10.60 13.41 12.89 12.28 11.31 13.71 13.60 12.76 12.31 12.68 10.22 13.83 9.95 12.64 10.33 13.07 12.06 11.91 13.17 13.59 11.83 10.66 13.09 10.67 11.20 12.27 12.19 11.94 10.01 11.71 14.36 14.26 12.29 15.20 12.23 13.22 11.32 12.80 9.91 13.46 10.31 9.66 11.54 11.39 13.48 12.70 12.63 7.99 12.49 10.87 12.10 13.48 13.14 12.56 12.21 12.61 12.56 10.64 8.80 13.09 13.54 13.45 11.08 13.43 11.83 12.62 13.10 13.94 13.21 11.93 10.41 12.49 13.94 12.34 12.48 13.54 14.50 13.93 13.29 12.58 14.05 12.62 12.27 12.28

EigenMS removes sample-to-sample variability.

Code
Label = as.matrix(df[1,-1]) %>%
  t(.) %>%
  as.data.frame(.) %>%
  `colnames<-`(., "Label") %>%
  rownames_to_column(., var = "sample")

color_list = sample_annotation_to_colors(Label,sample_id_col = "sample", factor_columns = c("Label"), numeric_columns = NULL)

# after log2 transformation
log2_d1_long = matrix_to_long(log2_d1, sample_id_col = "sample")

plot_boxplot(log2_d1_long, Label, sample_id_col = "sample", batch_col = "Label", color_scheme = color_list[["Label"]], ylimits = c(-15,30)) + ylab("Intensity (log2 scale)") # y-range = 45 for comparison purpose

Code
#after normalization
norm_d1_long = matrix_to_long(norm_d1_mod, sample_id_col = "sample")

plot_boxplot(norm_d1_long, Label, sample_id_col = "sample", batch_col = "Label", color_scheme = color_list[["Label"]], ylimits = c(-15,30)) + ylab("Intensity (log2 scale, after normalization)") # y-range = 45 for comparison purpose

Univariate analysis

Univariate statistic analysis will proceed for each pairs of comparison. For each pair,

Step 1, differential analysis;

  • t-test

  • Wilcoxon rank-sum test

For all statistical tests, the Benjamini-Hochberg (BH) procedure was applied to correct for multiple hypothesis testing.

Step 2, fold change, both linear and log2;

Step 3, regulation shown in volcano plot.

  • A feature is considered unregulated when FC(log2) > 0.6 (or FC(lin) > 1.5);

  • A feature is considered downregulated when FC(log2) < -0.6 (or FC(lin) < -1.5).

Code
d5 <- rbind.data.frame(labels_d1, norm_d1_mod) 
d5_mod <- t(d5) %>%
  as.data.frame(.) %>%
  rownames_to_column(., var = "rowname") %>%
  as_tibble() %>%
  #dplyr::rename(., Label = class) %>%
  mutate(across(-c(Label,rowname), as.numeric)) %>%
  #rename_with(str_trim)
  column_to_rownames(., var = "rowname")
grps = as.factor(t(labels_d1))
Code
temp_d <- d5_mod %>%
        mutate(across(-Label, ~ 2^(.) )) %>% # d3_mod is log-scale number, this step will de-log and change data back to linear number
        group_by(Label) %>%
        summarise(across(everything(), mean))

print(paste("Order of Fold Change:", temp_d$Label[2], "over", temp_d$Label[1], sep = " "))
[1] "Order of Fold Change: IC/BPS over Control"
Code
uni_res <- do_univariate(d5_mod)

uni_res <- uni_res %>%
        rowwise() %>%
        mutate(padj = min(c(BHT, BHW))) %>%
        # get the lowest padj
        ungroup() %>%
        mutate(`-log10padj` = -log10(padj))

#uni_res_annotation = uni_res %>% left_join(., feature_meta, by = c("variable" = "Feature"))

#uni_res_annotation %>% create_dt()

uni_res %>% 
        knitr::kable(., digits = 3, "html") %>%
        kableExtra::kable_styling(bootstrap_options = c("striped", "hover", "condensed", "responsive")) %>%
        kableExtra::scroll_box(width = "100%", height = "500px")
variable pT BHT pW BHW FC(lin) FC(log2) padj -log10padj
AASLAGPHSIVGRA 0.000 0.000 0.000 0.000 2.020 1.014 0.000 3.699
AGKQLEDGRTLSD 0.895 0.921 0.863 0.933 0.951 -0.073 0.921 0.036
AGPSSPT 0.541 0.671 0.329 0.446 1.055 0.077 0.446 0.350
AIPVAQDLNAPSDWDSRGKDSYETSQL 0.887 0.917 0.475 0.592 1.186 0.246 0.592 0.227
AKADAAPDEKVLDSGF 0.060 0.124 0.015 0.041 1.338 0.420 0.041 1.390
AKADAAPDEKVLDSGFREIENK 0.002 0.011 0.000 0.002 1.745 0.803 0.002 2.677
AKVQWKVDNALQSGNSQE 0.031 0.076 0.024 0.058 1.191 0.252 0.058 1.239
ANKADRDQYEL 0.217 0.339 0.028 0.065 1.249 0.321 0.065 1.190
ANYPDLPSAYQPGIL 0.216 0.339 0.262 0.373 1.171 0.228 0.339 0.470
APHGPGL 0.183 0.303 0.218 0.323 1.133 0.180 0.303 0.518
APHGPGLI 0.770 0.850 0.803 0.892 0.942 -0.087 0.850 0.071
AQDLNAPSDWDSRGKDSYETSQL 0.032 0.077 0.037 0.079 1.777 0.829 0.077 1.116
AQLDEELGGTPVQSRVVQGKEPAHL 0.067 0.135 0.009 0.025 1.672 0.742 0.025 1.598
ASHTSDSDVPSGVTEVVVKL 0.239 0.363 0.255 0.370 0.922 -0.117 0.363 0.440
ASWDVEKTAI 0.279 0.397 0.621 0.744 1.728 0.789 0.397 0.401
ASWDVEKTAIF 0.068 0.136 0.179 0.280 1.433 0.519 0.136 0.867
AVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 0.042 0.095 0.075 0.142 1.359 0.442 0.095 1.021
AVALTKGGEARGEL 0.045 0.099 0.045 0.090 1.449 0.535 0.090 1.044
AVRLVFQDF 0.007 0.026 0.004 0.014 1.352 0.435 0.014 1.840
AWKADSSPVKAGVE 0.461 0.592 0.534 0.659 1.322 0.403 0.592 0.228
DADLADGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 0.000 0.000 0.000 0.000 2.265 1.179 0.000 11.401
DAHKSEVAHRFKDLGEEN 0.001 0.006 0.002 0.008 3.580 1.840 0.006 2.229
DAPGQYGAYFHDDGF 0.185 0.303 0.179 0.280 1.077 0.107 0.280 0.554
DDEKNWGLSF 0.278 0.397 0.391 0.518 0.740 -0.434 0.397 0.401
DDQSAETHSHKQSRLY 0.000 0.001 0.000 0.000 2.018 1.013 0.000 3.723
DEAGSEADHEGTHSTK 0.447 0.578 0.304 0.418 1.294 0.371 0.418 0.378
DEAGSEADHEGTHSTKR 0.786 0.858 1.000 1.000 0.756 -0.403 0.858 0.066
DEAGSEADHEGTHSTKRG 0.712 0.803 0.688 0.789 0.721 -0.472 0.789 0.103
DEELGGTPVQSRVVQGKEPAHL 0.000 0.000 0.000 0.000 1.886 0.915 0.000 3.840
DGQPGAKGEPGDAGAKGDAGPPGP 0.001 0.004 0.000 0.001 1.647 0.720 0.001 3.240
DGVPGKDGPRGPT 0.045 0.099 0.042 0.085 1.251 0.323 0.085 1.071
DGVPGKDGPRGPTGP 0.000 0.001 0.000 0.000 1.597 0.676 0.000 3.401
DGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 0.000 0.000 0.000 0.000 2.034 1.024 0.000 9.383
DHDVGSELPPEGVL 0.679 0.785 0.639 0.749 0.992 -0.012 0.749 0.126
DHDVGSELPPEGVLGAL 0.760 0.848 0.997 1.000 0.905 -0.145 0.848 0.071
DHDVGSELPPEGVLGALL 0.651 0.767 0.829 0.902 1.209 0.274 0.767 0.115
DLADGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 0.000 0.000 0.000 0.000 1.636 0.710 0.000 5.453
DQSRVLNLGPITR 0.004 0.017 0.002 0.009 2.032 1.023 0.009 2.051
DVQNVAAAPELAMGALEL 0.524 0.662 0.929 0.980 1.050 0.070 0.662 0.179
EAEDLQVGQVELGGGPGAGSLQP 0.410 0.546 0.194 0.297 1.231 0.300 0.297 0.527
EAEDLQVGQVELGGGPGAGSLQPLAL 0.008 0.026 0.006 0.019 1.746 0.804 0.019 1.716
EAEDLQVGQVELGGGPGAGSLQPLALEGS 0.004 0.017 0.005 0.017 1.611 0.688 0.017 1.767
EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ 0.274 0.397 0.312 0.427 1.065 0.091 0.397 0.401
EDPQGDAAQKTDTSHHDQDHPTF 0.000 0.000 0.000 0.000 2.057 1.040 0.000 4.434
EEAPSLRPAPPPISGGGY 0.000 0.003 0.000 0.002 1.749 0.807 0.002 2.677
EEKAVADTRDQADGSRASVDSGSSEEQGGSSRA 0.022 0.058 0.028 0.065 1.319 0.399 0.058 1.240
EEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 0.000 0.000 0.000 0.000 1.756 0.813 0.000 4.333
EETLTHTITKL 0.060 0.124 0.074 0.141 1.387 0.472 0.124 0.906
EVDETYVPKEFNAET 0.118 0.220 0.110 0.199 1.256 0.329 0.199 0.701
EVQVFAPANALPARSEA 0.806 0.872 0.963 0.996 0.817 -0.291 0.872 0.059
FAEEKAVADTRDQADGSR 0.007 0.026 0.008 0.025 1.465 0.551 0.025 1.603
FAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRA 0.013 0.040 0.018 0.047 1.330 0.411 0.040 1.403
FAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 0.000 0.000 0.000 0.001 1.799 0.847 0.000 3.536
FDSDPITVTVPVEV 0.850 0.897 0.627 0.747 0.983 -0.025 0.747 0.127
FESFGDL 0.152 0.269 0.221 0.326 1.691 0.758 0.269 0.570
FKQETLPSKSNESHDHMDD 0.003 0.017 0.008 0.025 1.475 0.561 0.017 1.771
FKQETLPSKSNESHDHMDDM 0.001 0.004 0.000 0.001 1.812 0.858 0.001 3.073
FKSLPGQNEDL 0.005 0.018 0.003 0.013 1.938 0.954 0.013 1.893
FQTPSYTQPYQGSSVTL 0.963 0.977 0.889 0.952 1.307 0.386 0.952 0.021
FQVRANSAGATRA 0.020 0.056 0.031 0.068 1.463 0.549 0.056 1.251
FRFAGNYDL 0.181 0.303 0.166 0.264 1.375 0.460 0.264 0.578
FRTQTAPGGQGAPWAEEL 0.245 0.365 0.158 0.258 1.471 0.557 0.258 0.588
FRVVAQGVGIPEDS 0.002 0.011 0.003 0.012 1.643 0.716 0.011 1.943
FRVVAQGVGIPEDSIF 0.148 0.264 0.008 0.025 1.452 0.538 0.025 1.607
FRVVAQGVGIPEDSIFT 0.277 0.397 0.112 0.199 1.279 0.355 0.199 0.701
FSSPHGKDLL 0.032 0.077 0.042 0.086 1.471 0.557 0.077 1.112
FTVRMAL 0.033 0.079 0.028 0.065 1.163 0.218 0.065 1.190
G(+42.01)DKPIWEQIGSSF 0.041 0.094 0.038 0.080 1.227 0.295 0.080 1.099
GPKWPEPVF 0.178 0.303 0.153 0.252 1.644 0.717 0.252 0.599
GRLASPGFPGE 0.014 0.040 0.034 0.073 1.849 0.887 0.040 1.394
GRLASPGFPGEY 0.947 0.965 0.983 1.000 1.198 0.260 0.965 0.015
GRPEAQPPPLSSEHKEPVAGDAVPGPKDGSAPEVRGA 0.000 0.003 0.001 0.006 2.169 1.117 0.003 2.582
HASLDKF 0.036 0.084 0.009 0.026 1.377 0.461 0.026 1.593
HQDWLNGKE 0.496 0.632 0.415 0.539 1.093 0.128 0.539 0.269
HSARPGAPPPQPLDL 0.006 0.023 0.003 0.014 1.843 0.882 0.014 1.861
IAVEWESNGQPENNYKTTPPVL 0.215 0.339 0.120 0.211 1.387 0.472 0.211 0.675
IAVEWESNGQPENNYKTTPPVLDSDGSF 0.540 0.671 0.651 0.757 0.890 -0.168 0.671 0.173
IDQSRVLNLGPITR 0.001 0.004 0.001 0.005 1.972 0.979 0.004 2.395
IDWTKIEPSVNF 0.015 0.044 0.010 0.029 1.315 0.395 0.029 1.538
IEVDGRVYHVGLGD 0.082 0.159 0.132 0.226 1.666 0.737 0.159 0.799
IILEHHVAQEPSPGQPSTF 0.000 0.000 0.000 0.000 1.900 0.926 0.000 3.955
IKFPEPGAIKVPEQG 0.029 0.072 0.026 0.062 1.738 0.797 0.062 1.205
IPGGLSEAKPATPEIQE 0.354 0.474 0.633 0.749 1.216 0.283 0.474 0.324
IPVKQADSGSSEEKQL 0.019 0.053 0.021 0.052 1.327 0.408 0.052 1.283
IPVKQADSGSSEEKQLYNKYPDA 0.006 0.023 0.005 0.018 1.538 0.621 0.018 1.754
IPVKQADSGSSEEKQLYNKYPDAVA 0.000 0.000 0.000 0.000 3.287 1.717 0.000 5.664
IPVKQADSGSSEEKQLYNKYPDAVAT 0.000 0.000 0.000 0.000 2.060 1.042 0.000 5.540
IQLQPLQEPESW 0.139 0.252 0.151 0.250 1.192 0.254 0.250 0.602
ISQDNALRDEMRA 0.823 0.878 0.896 0.954 0.985 -0.021 0.878 0.057
ISWDGLDSGKL 0.926 0.949 0.597 0.724 0.984 -0.024 0.724 0.140
IVDKVKPQL 0.882 0.917 0.803 0.892 1.001 0.001 0.892 0.050
IVLWQPVTADL 0.131 0.239 0.095 0.176 1.661 0.732 0.176 0.755
KANDESNEHSDVIDSQEL 0.111 0.209 0.095 0.176 1.335 0.417 0.176 0.755
KELKFVTL 0.066 0.135 0.124 0.217 1.363 0.446 0.135 0.870
KLGHPDT 0.691 0.785 0.341 0.461 0.677 -0.562 0.461 0.336
KPALPAGT 0.022 0.058 0.016 0.042 1.426 0.512 0.042 1.374
KTALQPMVSAL 0.247 0.366 0.058 0.113 1.239 0.309 0.113 0.947
LAQELPQQLTSPGYPEPYGKGQESSTD 0.000 0.000 0.000 0.000 2.328 1.219 0.000 3.401
LNAPSDWDSRGKDSYETSQL 0.000 0.001 0.000 0.001 1.779 0.831 0.001 2.972
LNLGPITR 0.026 0.065 0.008 0.025 1.372 0.457 0.025 1.603
LQDFRVVAQGVGIPEDS 0.050 0.108 0.032 0.069 1.627 0.702 0.069 1.161
LREGRRGSIQVDGEEL 0.187 0.303 0.135 0.226 1.670 0.740 0.226 0.645
LRLPEKVPSAPPQE 0.000 0.001 0.000 0.001 1.668 0.738 0.001 3.153
LRLTEPADTITDA 0.004 0.017 0.002 0.008 1.690 0.757 0.008 2.073
LRVAPEEHPVL 0.007 0.026 0.006 0.021 1.786 0.836 0.021 1.674
LSDPDKVTIGLL 0.970 0.979 0.949 0.987 1.142 0.191 0.979 0.009
LSDPEQGVEVTGQYEREKAGF 0.000 0.001 0.000 0.001 1.901 0.927 0.001 3.003
LSDPEQGVEVTGQYEREKAGFSW 0.048 0.104 0.013 0.037 1.372 0.456 0.037 1.437
LSRQELFPFGPGQGDLE 0.053 0.112 0.018 0.048 1.224 0.292 0.048 1.323
LSRQELFPFGPGQGDLELEDGDD 0.273 0.397 0.163 0.264 1.452 0.538 0.264 0.578
LVIKGARDSHAGL 0.000 0.001 0.000 0.001 1.687 0.754 0.001 3.235
LVLTGYQVDKNKDDELTGF 0.347 0.469 0.177 0.279 1.238 0.308 0.279 0.554
LWQGVEVGEAGQGKDF 0.431 0.563 0.419 0.539 1.301 0.380 0.539 0.269
LWVGTGASEAEKTGAQEL 0.831 0.881 0.639 0.749 0.926 -0.111 0.749 0.126
MGPPGNPGP 0.004 0.018 0.002 0.009 1.618 0.694 0.009 2.051
MVEHTPDEESIDWTKIEPSVNF 0.244 0.365 0.042 0.085 1.457 0.543 0.085 1.071
NKEIPAWVPFDPAAQ 0.183 0.303 0.108 0.197 0.980 -0.029 0.197 0.705
NVAKGIRSF 0.000 0.001 0.000 0.001 1.590 0.669 0.001 3.235
PENEKGPFPKNL 0.240 0.363 0.202 0.307 1.174 0.232 0.307 0.513
PGKDGPRGPT 0.008 0.026 0.005 0.017 1.360 0.443 0.017 1.758
PGKDGPRGPTGP 0.597 0.719 0.909 0.964 0.841 -0.249 0.719 0.143
PILRHGIQY 0.005 0.019 0.003 0.013 1.948 0.962 0.013 1.893
PPPPPPPP 0.181 0.303 0.051 0.101 1.606 0.683 0.101 0.995
PRGHSGEPGLPGPPGP 0.001 0.006 0.005 0.017 1.410 0.495 0.006 2.229
PRYPVGKF 0.004 0.018 0.002 0.008 1.632 0.707 0.008 2.078
PSDWDSRGKDSYETSQL 0.159 0.276 0.266 0.376 1.275 0.351 0.276 0.559
PVAEELSHHENL 0.023 0.058 0.030 0.066 1.201 0.264 0.058 1.240
PVVPVHL 0.625 0.741 0.797 0.892 1.202 0.266 0.741 0.130
Q(-17.03)GQYDLDPLPPFPDHV 0.007 0.026 0.020 0.050 1.311 0.391 0.026 1.593
QVGQVELGGGPGAGSLQPLAL 0.174 0.300 0.166 0.264 1.561 0.642 0.264 0.578
RAHGQESAIF 0.010 0.031 0.022 0.053 1.576 0.656 0.031 1.505
RAHGQESAIFNE 0.004 0.018 0.009 0.026 1.543 0.626 0.018 1.737
RAPEPALEPESL 0.001 0.006 0.001 0.006 3.039 1.603 0.006 2.229
RPPGFSPF 0.158 0.276 0.025 0.061 1.378 0.463 0.061 1.215
S(+42.01)ETAPAAPAAAPPAEKAPVKK 0.001 0.006 0.001 0.006 1.353 0.437 0.006 2.228
S(+42.01)ETAPAAPAAPAPAEKTPVK 0.261 0.385 0.459 0.580 0.984 -0.023 0.385 0.415
S(+42.01)ETAPAAPAAPAPAEKTPVKK 0.001 0.004 0.001 0.003 1.345 0.428 0.003 2.466
S(+42.01)SYQQKQTFTPPPQL 0.304 0.422 0.258 0.373 1.271 0.346 0.373 0.429
SDVFAAGT 0.878 0.917 0.997 1.000 0.950 -0.074 0.917 0.038
SEDPINDGEWHRVTA 0.498 0.632 0.603 0.727 0.829 -0.271 0.632 0.199
SGSVIDQSRVLNLGPI 0.187 0.303 0.080 0.149 1.884 0.914 0.149 0.826
SGSVIDQSRVLNLGPIT 0.005 0.018 0.006 0.019 1.683 0.751 0.018 1.733
SGSVIDQSRVLNLGPITR 0.000 0.000 0.000 0.000 2.600 1.378 0.000 4.289
SIDWTKIEPSVNF 0.227 0.348 0.196 0.300 1.931 0.949 0.300 0.523
SKWSGPLSL 0.324 0.446 0.262 0.373 1.401 0.487 0.373 0.428
SQDASDGLQRLHM 0.013 0.039 0.004 0.017 1.419 0.505 0.017 1.771
SQDASDGLQRLHMLQ 0.000 0.003 0.000 0.001 1.947 0.961 0.001 3.268
SSSERAHQVLRI 0.022 0.058 0.007 0.021 1.561 0.642 0.021 1.674
SVIDQSRVLNLGPIT 0.130 0.239 0.135 0.226 1.131 0.177 0.226 0.645
SVIDQSRVLNLGPITR 0.021 0.056 0.032 0.068 1.554 0.636 0.056 1.248
TAQLDEELGGTPVQSRVVQGKEPAHL 0.027 0.068 0.026 0.062 2.031 1.022 0.062 1.205
TGYQVDKNKDDELTGF 0.799 0.869 0.829 0.902 1.097 0.133 0.869 0.061
TPLGPKWPEPVF 0.281 0.398 0.296 0.410 1.522 0.606 0.398 0.400
TTTPSKQSNNKYAASSY 0.425 0.560 0.512 0.635 1.046 0.065 0.560 0.252
TVDKSRWQQGNV 0.007 0.026 0.001 0.006 1.239 0.309 0.006 2.221
TWLNPDPSQKQNL 0.048 0.104 0.021 0.053 1.246 0.317 0.053 1.278
TWLNPDPSQKQNLLAPQNAVSSEETND 0.100 0.190 0.139 0.232 1.418 0.504 0.190 0.720
TYVPKEFNAET 0.213 0.339 0.209 0.311 0.860 -0.218 0.311 0.507
VADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 0.416 0.551 0.132 0.226 1.081 0.112 0.226 0.645
VAWKADGSPVKAGVE 0.994 0.995 0.803 0.892 0.876 -0.191 0.892 0.050
VAWKADSSPVKAGVE 0.689 0.785 0.823 0.902 0.999 -0.001 0.785 0.105
VDALHEIPVKKGEGAEL 0.010 0.031 0.012 0.032 1.402 0.487 0.031 1.505
VDISQDNALRDEMRA 0.075 0.149 0.112 0.199 1.341 0.424 0.149 0.825
VFEIGSPATTNGVVPADVIL 0.000 0.001 0.000 0.002 2.193 1.133 0.001 3.006
VGGGEQPPPAPAPRRE 0.000 0.000 0.000 0.000 1.475 0.561 0.000 4.647
VHLTPEEKSAVTAL 0.000 0.003 0.000 0.002 22.704 4.505 0.002 2.786
VIDQSRVLNLGPIT 0.864 0.906 0.810 0.894 1.089 0.123 0.894 0.049
VIDQSRVLNLGPITR 0.003 0.017 0.007 0.021 2.009 1.007 0.017 1.771
VIKGARDSHAGL 0.007 0.026 0.003 0.014 1.675 0.744 0.014 1.857
VKQADSGSSEEKQLYNKYPDAVA 0.001 0.004 0.000 0.001 1.663 0.734 0.001 3.105
VKQADSGSSEEKQLYNKYPDAVAT 0.022 0.058 0.006 0.020 1.400 0.485 0.020 1.700
VKVWPQQPSGEL 0.612 0.729 0.377 0.502 0.821 -0.285 0.502 0.299
VKVWPQQPSGELFE 0.766 0.850 0.657 0.757 0.982 -0.026 0.757 0.121
VLNLGPITR 0.013 0.039 0.003 0.013 1.462 0.548 0.013 1.889
VLTGYQVDKNKDDELTGF 0.693 0.785 0.580 0.711 1.034 0.048 0.711 0.148
VNVDEVGGEALGRL 0.052 0.111 0.032 0.068 1.555 0.637 0.068 1.166
VQVFAPANALP 0.674 0.785 0.657 0.757 0.926 -0.111 0.757 0.121
VQVFAPANALPARSEA 0.440 0.572 0.470 0.589 1.072 0.100 0.572 0.242
VQVFAPANALPARSEAA 0.291 0.409 0.182 0.282 1.217 0.284 0.282 0.550
VQVFAPANALPARSEAAAVQP 0.005 0.018 0.002 0.009 1.791 0.840 0.009 2.051
VSEDPINDGEWHRVTA 0.042 0.095 0.066 0.128 1.518 0.603 0.095 1.021
VSEDPINDGEWHRVTAL 0.742 0.832 0.444 0.564 1.227 0.295 0.564 0.249
VSLGSPSGEVSHPR 0.079 0.155 0.070 0.134 1.258 0.331 0.134 0.871
VSLGSPSGEVSHPRKT 0.018 0.052 0.011 0.031 1.358 0.442 0.031 1.511
VSWVPPPAENHNGIIRG 0.000 0.000 0.000 0.000 1.955 0.967 0.000 4.981
VVENGESSQGRF 0.586 0.710 0.882 0.950 1.718 0.781 0.710 0.149
VVENGESSQGRFSVQM 0.575 0.705 1.000 1.000 1.410 0.496 0.705 0.152
VVKLFDSDPITVTVPVEV 0.995 0.995 0.745 0.845 1.152 0.204 0.845 0.073
VVLPKHILD 0.665 0.779 0.346 0.464 0.899 -0.154 0.464 0.334
VVSLGSPSGEVSHPRKT 0.201 0.322 0.205 0.309 1.071 0.099 0.309 0.510
VVVHAGEDDLGRGGNQ 0.095 0.183 0.135 0.226 1.886 0.916 0.183 0.738
VVVKLFDSDPITVTVPVEV 0.304 0.422 0.405 0.533 1.204 0.268 0.422 0.375
WGKVNVDEVGGEAL 0.003 0.015 0.003 0.012 9.480 3.245 0.012 1.916
WGSPAASDDGRRTL 0.014 0.041 0.006 0.019 1.500 0.585 0.019 1.716
WLNPDPSQKQNLLAPQNAVSSEETND 0.684 0.785 0.592 0.721 1.058 0.081 0.721 0.142
WQGVEVGEAGQGKDF 0.346 0.469 0.292 0.410 1.450 0.536 0.410 0.387
WRQVEGM(+15.99)ED 0.779 0.855 0.976 1.000 0.977 -0.034 0.855 0.068
WRQVEGMED 0.584 0.710 0.439 0.561 0.878 -0.188 0.561 0.251
YADKPETTKEQL 0.004 0.018 0.003 0.013 1.384 0.469 0.013 1.893
YADKPETTKEQLGEF 0.575 0.705 0.707 0.806 1.175 0.233 0.705 0.152
YEKTDTDGKF 0.607 0.727 0.419 0.539 0.793 -0.335 0.539 0.269
YGRAPQLRETL 0.008 0.027 0.000 0.003 1.831 0.873 0.003 2.570
YKAIPVAQDL 0.347 0.469 0.410 0.536 1.460 0.545 0.469 0.329
YKAIPVAQDLNAPSDW 0.008 0.027 0.007 0.021 1.560 0.642 0.021 1.669
YKWKETL 0.003 0.017 0.004 0.017 1.572 0.653 0.017 1.782
YLAPNNLKPVVAEF 0.223 0.346 0.248 0.362 1.456 0.542 0.346 0.461
YQAEWDDYVPKL 0.144 0.259 0.296 0.410 1.422 0.508 0.259 0.587
YRITEATKTVGSDT 0.114 0.214 0.029 0.065 1.334 0.415 0.065 1.185
YRITEATKTVGSDTF 0.000 0.000 0.000 0.000 2.272 1.184 0.000 5.283
YSRTQTPRAEL 0.821 0.878 0.949 0.987 0.999 -0.001 0.878 0.057
YVVHTNYDE 0.824 0.878 0.976 1.000 1.023 0.033 0.878 0.057
YVVHTNYDEY 0.534 0.669 0.936 0.982 1.495 0.580 0.669 0.174

Univariate analysis identified 71 peptides with a p-value less than 0.05 from both the BH-corrected t test and Wilcoxon rank-sum tests. These peptides exhibited a statistically significant differential abundance between IC/BPS and healthy controls. The 71 differential peptides were degradation products from a variety of proteins, including several previously associated with IC/BPS from prior proteomics studies.

Code
# get DE features only tibble
uni_res_filt <- uni_res %>%
        dplyr::filter(BHT < FDR & BHW < FDR) %>%
        mutate(status = case_when(`FC(log2)` < - 0.6 ~ "Down",
                                  `FC(log2)` > 0.6 ~ "Up") )

if (nrow(uni_res_filt) == 0){
        print(paste("There is no significant differentiated features between",
                    temp_d$Label[2], "and", temp_d$Label[1], sep = " "))
} else {
        uni_res_filt = uni_res_filt #%>%
                #left_join(., feature_meta, by = c("variable" = "Feature"))
        
        #write.csv(uni_res_filt, file = paste(combo_list[[i]][1], "vs", combo_list[[i]][2], ".csv", sep = ""))
        uni_res_filt %>% 
          knitr::kable(., digits = 3, "html") %>%
          kableExtra::kable_styling(bootstrap_options = c("striped", "hover", "condensed", "responsive")) %>%
          kableExtra::scroll_box(width = "100%", height = "500px")
}
variable pT BHT pW BHW FC(lin) FC(log2) padj -log10padj status
AASLAGPHSIVGRA 0.000 0.000 0.000 0.000 2.020 1.014 0.000 3.699 Up
AKADAAPDEKVLDSGFREIENK 0.002 0.011 0.000 0.002 1.745 0.803 0.002 2.677 Up
AVRLVFQDF 0.007 0.026 0.004 0.014 1.352 0.435 0.014 1.840 NA
DADLADGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 0.000 0.000 0.000 0.000 2.265 1.179 0.000 11.401 Up
DAHKSEVAHRFKDLGEEN 0.001 0.006 0.002 0.008 3.580 1.840 0.006 2.229 Up
DDQSAETHSHKQSRLY 0.000 0.001 0.000 0.000 2.018 1.013 0.000 3.723 Up
DEELGGTPVQSRVVQGKEPAHL 0.000 0.000 0.000 0.000 1.886 0.915 0.000 3.840 Up
DGQPGAKGEPGDAGAKGDAGPPGP 0.001 0.004 0.000 0.001 1.647 0.720 0.001 3.240 Up
DGVPGKDGPRGPTGP 0.000 0.001 0.000 0.000 1.597 0.676 0.000 3.401 Up
DGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 0.000 0.000 0.000 0.000 2.034 1.024 0.000 9.383 Up
DLADGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 0.000 0.000 0.000 0.000 1.636 0.710 0.000 5.453 Up
DQSRVLNLGPITR 0.004 0.017 0.002 0.009 2.032 1.023 0.009 2.051 Up
EAEDLQVGQVELGGGPGAGSLQPLAL 0.008 0.026 0.006 0.019 1.746 0.804 0.019 1.716 Up
EAEDLQVGQVELGGGPGAGSLQPLALEGS 0.004 0.017 0.005 0.017 1.611 0.688 0.017 1.767 Up
EDPQGDAAQKTDTSHHDQDHPTF 0.000 0.000 0.000 0.000 2.057 1.040 0.000 4.434 Up
EEAPSLRPAPPPISGGGY 0.000 0.003 0.000 0.002 1.749 0.807 0.002 2.677 Up
EEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 0.000 0.000 0.000 0.000 1.756 0.813 0.000 4.333 Up
FAEEKAVADTRDQADGSR 0.007 0.026 0.008 0.025 1.465 0.551 0.025 1.603 NA
FAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRA 0.013 0.040 0.018 0.047 1.330 0.411 0.040 1.403 NA
FAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 0.000 0.000 0.000 0.001 1.799 0.847 0.000 3.536 Up
FKQETLPSKSNESHDHMDD 0.003 0.017 0.008 0.025 1.475 0.561 0.017 1.771 NA
FKQETLPSKSNESHDHMDDM 0.001 0.004 0.000 0.001 1.812 0.858 0.001 3.073 Up
FKSLPGQNEDL 0.005 0.018 0.003 0.013 1.938 0.954 0.013 1.893 Up
FRVVAQGVGIPEDS 0.002 0.011 0.003 0.012 1.643 0.716 0.011 1.943 Up
GRPEAQPPPLSSEHKEPVAGDAVPGPKDGSAPEVRGA 0.000 0.003 0.001 0.006 2.169 1.117 0.003 2.582 Up
HSARPGAPPPQPLDL 0.006 0.023 0.003 0.014 1.843 0.882 0.014 1.861 Up
IDQSRVLNLGPITR 0.001 0.004 0.001 0.005 1.972 0.979 0.004 2.395 Up
IDWTKIEPSVNF 0.015 0.044 0.010 0.029 1.315 0.395 0.029 1.538 NA
IILEHHVAQEPSPGQPSTF 0.000 0.000 0.000 0.000 1.900 0.926 0.000 3.955 Up
IPVKQADSGSSEEKQLYNKYPDA 0.006 0.023 0.005 0.018 1.538 0.621 0.018 1.754 Up
IPVKQADSGSSEEKQLYNKYPDAVA 0.000 0.000 0.000 0.000 3.287 1.717 0.000 5.664 Up
IPVKQADSGSSEEKQLYNKYPDAVAT 0.000 0.000 0.000 0.000 2.060 1.042 0.000 5.540 Up
LAQELPQQLTSPGYPEPYGKGQESSTD 0.000 0.000 0.000 0.000 2.328 1.219 0.000 3.401 Up
LNAPSDWDSRGKDSYETSQL 0.000 0.001 0.000 0.001 1.779 0.831 0.001 2.972 Up
LRLPEKVPSAPPQE 0.000 0.001 0.000 0.001 1.668 0.738 0.001 3.153 Up
LRLTEPADTITDA 0.004 0.017 0.002 0.008 1.690 0.757 0.008 2.073 Up
LRVAPEEHPVL 0.007 0.026 0.006 0.021 1.786 0.836 0.021 1.674 Up
LSDPEQGVEVTGQYEREKAGF 0.000 0.001 0.000 0.001 1.901 0.927 0.001 3.003 Up
LVIKGARDSHAGL 0.000 0.001 0.000 0.001 1.687 0.754 0.001 3.235 Up
MGPPGNPGP 0.004 0.018 0.002 0.009 1.618 0.694 0.009 2.051 Up
NVAKGIRSF 0.000 0.001 0.000 0.001 1.590 0.669 0.001 3.235 Up
PGKDGPRGPT 0.008 0.026 0.005 0.017 1.360 0.443 0.017 1.758 NA
PILRHGIQY 0.005 0.019 0.003 0.013 1.948 0.962 0.013 1.893 Up
PRGHSGEPGLPGPPGP 0.001 0.006 0.005 0.017 1.410 0.495 0.006 2.229 NA
PRYPVGKF 0.004 0.018 0.002 0.008 1.632 0.707 0.008 2.078 Up
RAHGQESAIFNE 0.004 0.018 0.009 0.026 1.543 0.626 0.018 1.737 Up
RAPEPALEPESL 0.001 0.006 0.001 0.006 3.039 1.603 0.006 2.229 Up
S(+42.01)ETAPAAPAAAPPAEKAPVKK 0.001 0.006 0.001 0.006 1.353 0.437 0.006 2.228 NA
S(+42.01)ETAPAAPAAPAPAEKTPVKK 0.001 0.004 0.001 0.003 1.345 0.428 0.003 2.466 NA
SGSVIDQSRVLNLGPIT 0.005 0.018 0.006 0.019 1.683 0.751 0.018 1.733 Up
SGSVIDQSRVLNLGPITR 0.000 0.000 0.000 0.000 2.600 1.378 0.000 4.289 Up
SQDASDGLQRLHM 0.013 0.039 0.004 0.017 1.419 0.505 0.017 1.771 NA
SQDASDGLQRLHMLQ 0.000 0.003 0.000 0.001 1.947 0.961 0.001 3.268 Up
TVDKSRWQQGNV 0.007 0.026 0.001 0.006 1.239 0.309 0.006 2.221 NA
VDALHEIPVKKGEGAEL 0.010 0.031 0.012 0.032 1.402 0.487 0.031 1.505 NA
VFEIGSPATTNGVVPADVIL 0.000 0.001 0.000 0.002 2.193 1.133 0.001 3.006 Up
VGGGEQPPPAPAPRRE 0.000 0.000 0.000 0.000 1.475 0.561 0.000 4.647 NA
VHLTPEEKSAVTAL 0.000 0.003 0.000 0.002 22.704 4.505 0.002 2.786 Up
VIDQSRVLNLGPITR 0.003 0.017 0.007 0.021 2.009 1.007 0.017 1.771 Up
VIKGARDSHAGL 0.007 0.026 0.003 0.014 1.675 0.744 0.014 1.857 Up
VKQADSGSSEEKQLYNKYPDAVA 0.001 0.004 0.000 0.001 1.663 0.734 0.001 3.105 Up
VLNLGPITR 0.013 0.039 0.003 0.013 1.462 0.548 0.013 1.889 NA
VQVFAPANALPARSEAAAVQP 0.005 0.018 0.002 0.009 1.791 0.840 0.009 2.051 Up
VSWVPPPAENHNGIIRG 0.000 0.000 0.000 0.000 1.955 0.967 0.000 4.981 Up
WGKVNVDEVGGEAL 0.003 0.015 0.003 0.012 9.480 3.245 0.012 1.916 Up
WGSPAASDDGRRTL 0.014 0.041 0.006 0.019 1.500 0.585 0.019 1.716 NA
YADKPETTKEQL 0.004 0.018 0.003 0.013 1.384 0.469 0.013 1.893 NA
YGRAPQLRETL 0.008 0.027 0.000 0.003 1.831 0.873 0.003 2.570 Up
YKAIPVAQDLNAPSDW 0.008 0.027 0.007 0.021 1.560 0.642 0.021 1.669 Up
YKWKETL 0.003 0.017 0.004 0.017 1.572 0.653 0.017 1.782 Up
YRITEATKTVGSDTF 0.000 0.000 0.000 0.000 2.272 1.184 0.000 5.283 Up

Interestingly, all of the differential peptides were found in a higher abundance in IC/BPS relative to control samples.

Code
# volcano plot
volcano_plot(uni_res, feature_col = "variable", fdr = FDR, log2fc = LOG2FC, save = FALSE)

Code
# heatmap
anno <- data.frame(Label = as.factor(t(d5)[, "Label"])) 
hm <- d5[-1, d5[1,] %in% levels(grps) ] %>%
        rownames_to_column("variable") %>%
        mutate(across(-variable, as.numeric)) %>%
        dplyr::filter(., variable %in% uni_res_filt$variable)

#heatmap(hm, feature_col = "variable", sample_anno = anno, rowname_switch = TRUE, save = TRUE, filename = "heatmap.png", folder = getwd(), width = 15, height = 10)
knitr::include_graphics(path = "heatmap.png")

Multivariate analysis

Supervised PLS-DA is included to assist feature selection, as one of the goal of this study is to identifying putative peptide biomarkers to distinguish between IC/BPS patient urine samples from control urine samples.

Code
label = as.character(norm_d1[1, ])

plsda_full <- pls_da(norm_d1_mod, label, WORKING_DIR=getwd())

Code
plsda_full_res <- plsda_full[[1]]
plsda_full_plot <- plsda_full[[2]]
plsda_full_vip <- plsda_full[[3]]
Code
pls_da_score = plsda_full_res@scoreMN %>%
        as.data.frame(.) %>%
        rownames_to_column(., var = "name") %>%
        merge(rownames_to_column(as.data.frame(t(labels_d1)), var = "name"), by = "name")

#write.csv(pls_da_score, file = "after_norm_plsda_score.csv")
#plsda_merged <- merge(t(rbind.data.frame(labels_d1, norm_d1_mod)),
#                      plsda_full_res@scoreMN, by=0)
Code
vip = tibble("VIP" = names(plsda_full_vip),
        "score" = plsda_full_vip ) %>%
  mutate(across(c("score"), ~round(.x, 4))) 

vip %>% knitr::kable(., digits = 3, "html") %>%
        kableExtra::kable_styling(bootstrap_options = c("striped", "hover", "condensed", "responsive")) %>%
        kableExtra::scroll_box(width = "100%", height = "500px")
VIP score
DGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 2.586
DADLADGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 2.233
DLADGVSGGEGKGGSDGGGSHRKEGEEADAPGVIPGIVG 2.125
YRITEATKTVGSDTF 2.008
VGGGEQPPPAPAPRRE 2.006
VSWVPPPAENHNGIIRG 1.997
IPVKQADSGSSEEKQLYNKYPDAVAT 1.956
EDPQGDAAQKTDTSHHDQDHPTF 1.912
SGSVIDQSRVLNLGPITR 1.884
EEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 1.773
AASLAGPHSIVGRA 1.766
DEELGGTPVQSRVVQGKEPAHL 1.748
IPVKQADSGSSEEKQLYNKYPDAVA 1.746
FAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 1.711
IILEHHVAQEPSPGQPSTF 1.707
LAQELPQQLTSPGYPEPYGKGQESSTD 1.655
LVIKGARDSHAGL 1.614
DDQSAETHSHKQSRLY 1.607
NVAKGIRSF 1.600
LSDPEQGVEVTGQYEREKAGF 1.591
DGVPGKDGPRGPTGP 1.580
VFEIGSPATTNGVVPADVIL 1.575
LNAPSDWDSRGKDSYETSQL 1.565
LRLPEKVPSAPPQE 1.561
GRPEAQPPPLSSEHKEPVAGDAVPGPKDGSAPEVRGA 1.497
S(+42.01)ETAPAAPAAPAPAEKTPVKK 1.490
VHLTPEEKSAVTAL 1.458
SQDASDGLQRLHMLQ 1.449
EEAPSLRPAPPPISGGGY 1.449
PRGHSGEPGLPGPPGP 1.441
DGQPGAKGEPGDAGAKGDAGPPGP 1.438
FKQETLPSKSNESHDHMDDM 1.431
IDQSRVLNLGPITR 1.411
VKQADSGSSEEKQLYNKYPDAVA 1.411
DAHKSEVAHRFKDLGEEN 1.401
S(+42.01)ETAPAAPAAAPPAEKAPVKK 1.400
RAPEPALEPESL 1.365
AKADAAPDEKVLDSGFREIENK 1.282
FKQETLPSKSNESHDHMDD 1.278
FRVVAQGVGIPEDS 1.274
PRYPVGKF 1.253
RAHGQESAIFNE 1.251
WGKVNVDEVGGEAL 1.244
VQVFAPANALPARSEAAAVQP 1.222
YKWKETL 1.222
LRLTEPADTITDA 1.214
VIDQSRVLNLGPITR 1.212
YADKPETTKEQL 1.212
VSLGSPSGEVSHPRKT 1.208
DQSRVLNLGPITR 1.202
PGKDGPRGPT 1.199
MGPPGNPGP 1.190
EAEDLQVGQVELGGGPGAGSLQPLALEGS 1.189
FKSLPGQNEDL 1.181
TAQLDEELGGTPVQSRVVQGKEPAHL 1.179
PILRHGIQY 1.172
SGSVIDQSRVLNLGPIT 1.165
IPVKQADSGSSEEKQLYNKYPDA 1.151
TVDKSRWQQGNV 1.143
VIKGARDSHAGL 1.142
HSARPGAPPPQPLDL 1.139
YGRAPQLRETL 1.136
FAEEKAVADTRDQADGSR 1.131
PVAEELSHHENL 1.131
EAEDLQVGQVELGGGPGAGSLQPLAL 1.119
Q(-17.03)GQYDLDPLPPFPDHV 1.117
RAHGQESAIF 1.111
AVRLVFQDF 1.109
LRVAPEEHPVL 1.106
YKAIPVAQDLNAPSDW 1.102
SVIDQSRVLNLGPITR 1.076
VDALHEIPVKKGEGAEL 1.074
GRLASPGFPGE 1.038
VLNLGPITR 1.036
FAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRA 1.036
SQDASDGLQRLHM 1.032
WGSPAASDDGRRTL 1.028
SSSERAHQVLRI 1.024
IDWTKIEPSVNF 1.002
FQVRANSAGATRA 0.993
EVDETYVPKEFNAET 0.987
FSSPHGKDLL 0.985
IKFPEPGAIKVPEQG 0.980
IPVKQADSGSSEEKQL 0.977
VSLGSPSGEVSHPR 0.976
EEKAVADTRDQADGSRASVDSGSSEEQGGSSRA 0.974
VKQADSGSSEEKQLYNKYPDAVAT 0.959
KPALPAGT 0.958
AQLDEELGGTPVQSRVVQGKEPAHL 0.950
LNLGPITR 0.937
AQDLNAPSDWDSRGKDSYETSQL 0.913
HASLDKF 0.901
AKVQWKVDNALQSGNSQE 0.895
LSDPEQGVEVTGQYEREKAGFSW 0.887
VSEDPINDGEWHRVTA 0.884
FTVRMAL 0.882
G(+42.01)DKPIWEQIGSSF 0.871
AVADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 0.870
LQDFRVVAQGVGIPEDS 0.860
VVSLGSPSGEVSHPRKT 0.860
AVALTKGGEARGEL 0.854
TWLNPDPSQKQNL 0.854
DGVPGKDGPRGPT 0.845
YLAPNNLKPVVAEF 0.833
AKADAAPDEKVLDSGF 0.828
LSRQELFPFGPGQGDLE 0.814
ASWDVEKTAIF 0.809
VNVDEVGGEALGRL 0.808
KELKFVTL 0.804
SGSVIDQSRVLNLGPI 0.787
EETLTHTITKL 0.786
IAVEWESNGQPENNYKTTPPVL 0.779
PSDWDSRGKDSYETSQL 0.748
TWLNPDPSQKQNLLAPQNAVSSEETND 0.748
VDISQDNALRDEMRA 0.746
KANDESNEHSDVIDSQEL 0.744
IEVDGRVYHVGLGD 0.730
SVIDQSRVLNLGPIT 0.717
VVVHAGEDDLGRGGNQ 0.710
ANYPDLPSAYQPGIL 0.706
DAPGQYGAYFHDDGF 0.684
IVLWQPVTADL 0.675
YRITEATKTVGSDT 0.663
FRVVAQGVGIPEDSIF 0.656
IQLQPLQEPESW 0.652
APHGPGL 0.650
SEDPINDGEWHRVTA 0.644
GPKWPEPVF 0.628
MVEHTPDEESIDWTKIEPSVNF 0.628
VQVFAPANALPARSEAA 0.625
FESFGDL 0.619
YQAEWDDYVPKL 0.613
NKEIPAWVPFDPAAQ 0.606
RPPGFSPF 0.594
FRTQTAPGGQGAPWAEEL 0.591
FRFAGNYDL 0.585
PPPPPPPP 0.581
QVGQVELGGGPGAGSLQPLAL 0.577
WRQVEGMED 0.576
LREGRRGSIQVDGEEL 0.568
PENEKGPFPKNL 0.555
TPLGPKWPEPVF 0.552
FRVVAQGVGIPEDSIFT 0.539
LSRQELFPFGPGQGDLELEDGDD 0.539
SIDWTKIEPSVNF 0.538
VVVKLFDSDPITVTVPVEV 0.538
ANKADRDQYEL 0.537
LWQGVEVGEAGQGKDF 0.535
TYVPKEFNAET 0.526
HQDWLNGKE 0.521
S(+42.01)ETAPAAPAAPAPAEKTPVK 0.519
DDEKNWGLSF 0.513
VVENGESSQGRF 0.509
WQGVEVGEAGQGKDF 0.508
ASHTSDSDVPSGVTEVVVKL 0.504
IAVEWESNGQPENNYKTTPPVLDSDGSF 0.497
DHDVGSELPPEGVLGAL 0.496
KTALQPMVSAL 0.496
YADKPETTKEQLGEF 0.493
ASWDVEKTAI 0.490
VQVFAPANALPARSEA 0.486
EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ 0.484
AIPVAQDLNAPSDWDSRGKDSYETSQL 0.481
SKWSGPLSL 0.478
DEAGSEADHEGTHSTKRG 0.475
S(+42.01)SYQQKQTFTPPPQL 0.440
YVVHTNYDE 0.430
PGKDGPRGPTGP 0.427
TTTPSKQSNNKYAASSY 0.424
WRQVEGM(+15.99)ED 0.421
LVLTGYQVDKNKDDELTGF 0.421
VADTRDQADGSRASVDSGSSEEQGGSSRALVSTL 0.412
IPGGLSEAKPATPEIQE 0.403
PVVPVHL 0.401
YKAIPVAQDL 0.400
VKVWPQQPSGEL 0.400
LWVGTGASEAEKTGAQEL 0.381
DHDVGSELPPEGVLGALL 0.374
EVQVFAPANALPARSEA 0.374
EAEDLQVGQVELGGGPGAGSLQP 0.372
YVVHTNYDEY 0.365
VQVFAPANALP 0.324
DEAGSEADHEGTHSTK 0.320
VSEDPINDGEWHRVTAL 0.319
AWKADSSPVKAGVE 0.318
DVQNVAAAPELAMGALEL 0.310
VKVWPQQPSGELFE 0.300
FQTPSYTQPYQGSSVTL 0.292
AGPSSPT 0.274
VVENGESSQGRFSVQM 0.265
VLTGYQVDKNKDDELTGF 0.254
KLGHPDT 0.244
VAWKADGSPVKAGVE 0.239
VVKLFDSDPITVTVPVEV 0.229
LSDPDKVTIGLL 0.227
VAWKADSSPVKAGVE 0.220
VIDQSRVLNLGPIT 0.220
YEKTDTDGKF 0.218
FDSDPITVTVPVEV 0.217
DHDVGSELPPEGVL 0.210
GRLASPGFPGEY 0.208
ISQDNALRDEMRA 0.207
IVDKVKPQL 0.194
WLNPDPSQKQNLLAPQNAVSSEETND 0.193
APHGPGLI 0.192
VVLPKHILD 0.188
YSRTQTPRAEL 0.179
DEAGSEADHEGTHSTKR 0.154
AGKQLEDGRTLSD 0.125
SDVFAAGT 0.123
TGYQVDKNKDDELTGF 0.110
ISWDGLDSGKL 0.048
Code
#write.csv(vip, file = "after_norm_plsda_vip.csv")

AUROC

PLS-DA identified five peptides with a VIP coefficient greater than 2.00 and a p-value less than 0.05 from both a BH-corrected t test and a Wilcoxon rank-sum test. These five peptides were used as input to calculate a ROC curve, which yielded an AUC of 97.0% from a logistic regression model or an AUC of 92.4% from a random forest model.

Code
par(pty="s")
logistic_roc = roc(RF$Label,logistic.model$fitted.values, plot=TRUE, legacy.axes=TRUE, percent=TRUE, xlab="False Positive Percentage", ylab="True Postive Percentage", col="#377eb8", lwd=4, print.auc=TRUE,print.auc.cex=1.5 )
plot.roc(RF$Label, RF.model$votes[,1],percent=TRUE, col="#4daf4a", lwd=4, print.auc=TRUE, add=TRUE, print.auc.y=40, print.auc.cex=1.5)
legend(50, 20, legend=c("Logisitic Regression", "Random Forest"), col=c("#377eb8", "#4daf4a"), lwd=4, bty = 'n' )

Code
par(pty="m")

These results indicate that the five peptides provide a high predictive capability to distinguish urine from IC/BPS patients and healthy controls. ROC curves using the individual peptides generally showed a reduced predictive capability, demonstrating that the combination of peptide abundances is required for high predictive ability.

Code
# create list of combinations of all length from top.vip
list_top_vip = top.vip$VIP #rownames(top.vip)
roc_combo_list = do.call(c, lapply(seq_along(list_top_vip), combn, x = list_top_vip, simplify = FALSE))
Code
par(mfrow=c(2,3))

for (a in 1:5) {
  temp = data.frame(matrix(ncol = ncol(norm_d1), nrow = 0))
  colnames(temp) = colnames(norm_d1)

  for (i in 1:nrow(norm_d1)) {
    if (rownames(norm_d1)[i] == roc_combo_list[[a]]){
      temp = rbind(temp, norm_d1[i,])
    }
    i = i+1
  }
  temp = rbind(labels_d1,temp)

  # Random forest
  RF = as.data.frame(t(temp)) %>%
    rownames_to_column(.,var = "rowname")%>%
    mutate(across(-c(rowname,Label), as.numeric)) %>%
    column_to_rownames(., var = "rowname")%>%
    mutate_at(vars(Label), factor)
  set.seed(42)
  RF.model = randomForest::randomForest(Label ~ ., data = RF, importance=TRUE, proximity=TRUE)
  # Logistic regression
  logistic.model <- glm(Label ~ . , data = RF, family="binomial")

  #par(pty="s")
  roc(RF$Label,logistic.model$fitted.values,plot=TRUE, legacy.axes=TRUE, percent=TRUE, xlab="False Positive Percentage", ylab="True Postive Percentage", main = roc_combo_list[[a]], col="#377eb8", lwd=4, print.auc=TRUE, print.auc.cex=1.5)
  plot.roc(RF$Label, RF.model$votes[,1],percent=TRUE, col="#4daf4a", lwd=4, print.auc=TRUE, add=TRUE, print.auc.y=40, print.auc.cex=1.5)
  legend(50, 20, legend=c("Logisitic Regression", "Random Forest"), col=c("#377eb8", "#4daf4a"), lwd=4, bty = 'n' )
  #par(pty="m")
}

Reproducibility

The amount of time took to generate the report:

Code
Sys.time() - start_time
Time difference of 34.22251 secs

R session information:

Code
sessionInfo()
R version 4.2.1 (2022-06-23 ucrt)
Platform: x86_64-w64-mingw32/x64 (64-bit)
Running under: Windows 10 x64 (build 19045)

Matrix products: default

locale:
[1] LC_COLLATE=English_United States.utf8 
[2] LC_CTYPE=English_United States.utf8   
[3] LC_MONETARY=English_United States.utf8
[4] LC_NUMERIC=C                          
[5] LC_TIME=English_United States.utf8    

attached base packages:
[1] grid      stats     graphics  grDevices utils     datasets  methods  
[8] base     

other attached packages:
 [1] plotly_4.10.1       VennDiagram_1.7.3   futile.logger_1.4.3
 [4] wesanderson_0.3.6   RColorBrewer_1.1-3  extrafont_0.19     
 [7] pheatmap_1.0.12     ggrepel_0.9.3       ropls_1.28.2       
[10] ProteoMM_1.14.0     pROC_1.18.2         pcaMethods_1.88.0  
[13] Biobase_2.56.0      BiocGenerics_0.42.0 proBatch_1.11.0    
[16] cowplot_1.1.1       impute_1.70.0       knitr_1.43.1       
[19] janitor_2.2.0       openxlsx_4.2.5.2    lubridate_1.9.2    
[22] forcats_1.0.0       stringr_1.5.0       dplyr_1.1.2        
[25] purrr_1.0.1         readr_2.1.4         tidyr_1.3.0        
[28] tibble_3.2.1        ggplot2_3.4.2       tidyverse_2.0.0    

loaded via a namespace (and not attached):
  [1] backports_1.4.1             Hmisc_5.1-0                
  [3] qqman_0.1.8                 corrplot_0.92              
  [5] systemfonts_1.0.4           plyr_1.8.8                 
  [7] lazyeval_0.2.2              splines_4.2.1              
  [9] BiocParallel_1.30.4         GenomeInfoDb_1.32.4        
 [11] sva_3.44.0                  digest_0.6.31              
 [13] foreach_1.5.2               htmltools_0.5.5            
 [15] viridis_0.6.3               GO.db_3.15.0               
 [17] fansi_1.0.4                 ggfortify_0.4.16           
 [19] magrittr_2.0.3              checkmate_2.2.0            
 [21] memoise_2.0.1               cluster_2.1.4              
 [23] doParallel_1.0.17           tzdb_0.4.0                 
 [25] limma_3.52.4                fastcluster_1.2.3          
 [27] Biostrings_2.64.1           annotate_1.74.0            
 [29] matrixStats_0.63.0          svglite_2.1.1              
 [31] extrafontdb_1.0             timechange_0.2.0           
 [33] colorspace_2.1-0            rvest_1.0.3                
 [35] blob_1.2.4                  textshaping_0.3.6          
 [37] xfun_0.39                   crayon_1.5.2               
 [39] RCurl_1.98-1.12             jsonlite_1.8.4             
 [41] genefilter_1.78.0           lme4_1.1-33                
 [43] survival_3.5-5              iterators_1.0.14           
 [45] glue_1.6.2                  kableExtra_1.3.4           
 [47] gtable_0.3.3                zlibbioc_1.42.0            
 [49] XVector_0.36.0              webshot_0.5.4              
 [51] DelayedArray_0.22.0         Rttf2pt1_1.3.12            
 [53] scales_1.2.1                futile.options_1.0.1       
 [55] vsn_3.64.0                  DBI_1.1.3                  
 [57] edgeR_3.38.4                Rcpp_1.0.10                
 [59] MultiDataSet_1.24.0         viridisLite_0.4.2          
 [61] xtable_1.8-4                htmlTable_2.4.1            
 [63] foreign_0.8-84              bit_4.0.5                  
 [65] preprocessCore_1.58.0       Formula_1.2-5              
 [67] stats4_4.2.1                htmlwidgets_1.6.2          
 [69] httr_1.4.6                  calibrate_1.7.7            
 [71] farver_2.1.1                pkgconfig_2.0.3            
 [73] XML_3.99-0.14               nnet_7.3-19                
 [75] locfit_1.5-9.7              utf8_1.2.3                 
 [77] dynamicTreeCut_1.63-1       labeling_0.4.2             
 [79] tidyselect_1.2.0            rlang_1.1.1                
 [81] reshape2_1.4.4              AnnotationDbi_1.58.0       
 [83] munsell_0.5.0               tools_4.2.1                
 [85] cachem_1.0.8                cli_3.6.1                  
 [87] generics_0.1.3              RSQLite_2.3.1              
 [89] evaluate_0.21               fastmap_1.1.1              
 [91] ragg_1.2.5                  yaml_2.3.7                 
 [93] bit64_4.0.5                 zip_2.3.0                  
 [95] randomForest_4.7-1.1        KEGGREST_1.36.3            
 [97] nlme_3.1-162                formatR_1.14               
 [99] xml2_1.3.4                  compiler_4.2.1             
[101] rstudioapi_0.14             png_0.1-8                  
[103] affyio_1.66.0               stringi_1.7.12             
[105] highr_0.10                  lattice_0.21-8             
[107] Matrix_1.5-4                nloptr_2.0.3               
[109] vctrs_0.6.2                 pillar_1.9.0               
[111] lifecycle_1.0.3             BiocManager_1.30.20        
[113] pvca_1.36.0                 data.table_1.14.8          
[115] bitops_1.0-7                GenomicRanges_1.48.0       
[117] R6_2.5.1                    affy_1.74.0                
[119] gridExtra_2.3               IRanges_2.30.1             
[121] codetools_0.2-19            lambda.r_1.2.4             
[123] boot_1.3-28.1               MASS_7.3-60                
[125] SummarizedExperiment_1.26.1 withr_2.5.0                
[127] S4Vectors_0.34.0            GenomeInfoDbData_1.2.8     
[129] mgcv_1.8-42                 parallel_4.2.1             
[131] hms_1.1.3                   MultiAssayExperiment_1.22.0
[133] rpart_4.1.19                minqa_1.2.5                
[135] rmarkdown_2.21              snakecase_0.11.0           
[137] MatrixGenerics_1.8.1        WGCNA_1.72-1               
[139] base64enc_0.1-3            

Footnotes

  1. These authors contributed equally: Md Shadman Ridwan Abid and Haowen Qiu.↩︎

  2. These authors contributed equally: Md Shadman Ridwan Abid and Haowen Qiu.↩︎

  3. These authors contributed equally: Md Shadman Ridwan Abid and Haowen Qiu.↩︎